Refolding of proteins from inclusion bodies: Rational design and recipes

Applied Microbiology and Biotechnology

Volumn 92, Issue 2, 2011, Pages 241-251

  Basu, Anindya ^a   Li, Xiang ^a   Leong, Susanna Su Jan ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

Chromatography; Dynamic light scattering; Inclusion bodies; Refolding; Static light scattering

Indexed keywords

BACTERIAL PRODUCTION; BIOMANUFACTURING; BIOPROCESS DESIGN; BIOTECH INDUSTRY; BUFFER SYSTEM; FASTER RATES; GENE FUNCTION; HIGH QUALITY; INCLUSION BODIES; MONITORING AND CONTROLLING; PROTEIN PRODUCTION; PROTEIN REFOLDING; QUANTITATIVE INFORMATION; RAPID RATE; RATIONAL DESIGN; RECOMBINANT PROTEIN; REFOLDING; REFOLDING PROCESS; STATIC LIGHT SCATTERING;

BIOTECHNOLOGY; CHROMATOGRAPHY; DESIGN; DYNAMIC LIGHT SCATTERING; GENES; LIGHT SCATTERING; PROCESS DESIGN; PRODUCTION PLATFORMS; SCATTERING;

PROTEINS;

BUFFER; RECOMBINANT PROTEIN;

BACTERIUM; CHROMATOGRAPHY; GENETIC ANALYSIS; LIGHT SCATTERING; PROTEIN; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS;

ANALYTIC METHOD; CELL INCLUSION; CHROMATOGRAPHY; DIALYSIS; DILUTION; DYNAMIC LIGHT SCATTERING; GENE OVEREXPRESSION; HIGH HYDROSTATIC PRESSURE TECHNOLOGY; HUMAN; LIGHT SCATTERING; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVIEW; STATIC LIGHT SCATTERING;

ANIMALS; BACTERIA; HUMANS; INCLUSION BODIES; INDUSTRIAL MICROBIOLOGY; KINETICS; PROTEIN REFOLDING; RECOMBINANT PROTEINS;

EID: 82455175647     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3513-y     Document Type: Review

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