High potency and broad-spectrum antimicrobial peptides synthesized via ring-opening polymerization of α-Aminoacid-N-carboxyanhydrides

Biomacromolecules

Volumn 11, Issue 1, 2010, Pages 60-67

  Zhou, Chuncai ^a   Qi, Xiaobao ^a   Li, Peng ^a   Chen, Wei Ning ^a   Mouad, Lamrani ^b   Chang, Matthew W ^a   Leong, Susanna Su Jan ^a   Chan Park, Mary B ^a  

^a Nanyang Technological University   (Singapore)

^b MENICON Europe   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALBICANS; ANTIMICROBIAL PEPTIDE; CANDIDA ALBICANS; E. COLI; ESCHERICHIA COLI (E. COLI); GRAM-POSITIVE BACTERIUM; HIGH POTENCY; HIGH POTENTIAL; HYDROPHOBIC AMINO ACIDS; MEMBRANE DEPOLARIZATION; MEMBRANE DISRUPTION; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MINIMAL INHIBITORY CONCENTRATION; N-CARBOXYANHYDRIDES; NATURALLY OCCURRING; P.AERUGINOSA; PEPTIDE SYNTHESIS; PSEUDOMONAS AERUGINOSA; S. AUREUS; SEM; SEQUENTIAL SYNTHESIS; SERRATIA MARCESCENS; SOLID-PHASE;

ANTIBIOTICS; BACTERIA; ESCHERICHIA COLI; HYDROPHOBICITY; ORGANIC ACIDS; PEPTIDES; RING OPENING POLYMERIZATION; SYNTHESIS (CHEMICAL); TRANSITION METALS;

AMINO ACIDS;

ALANINE; ALPHA AMINO ACID; ALPHA AMINOACID N CARBOXYANHYDRIDE DERIVATIVE; LEUCINE; LYSINE; PHENYLALANINE; POLY(LYSINE CO ALANINE CO LEUCINE); POLY(LYSINE CO ALANINE); POLY(LYSINE CO LEUCINE); POLY(LYSINE CO PHENYLALANINE CO LEUCINE); POLY(LYSINE CO PHENYLALANINE); POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CANDIDA ALBICANS; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; HEMOLYSIS; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYMERIZATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RING OPENING; SERRATIA MARCESCENS;

AMINO ACIDS; ANHYDRIDES; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CIRCULAR DICHROISM; ERYTHROCYTES; FUNGI; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HEMOGLOBINS; HUMANS; MICROBIAL SENSITIVITY TESTS; POLYMERS;

CANDIDA ALBICANS; ESCHERICHIA COLI; FUNGI; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; POSIBACTERIA; PSEUDOMONAS AERUGINOSA; SERRATIA MARCESCENS; STAPHYLOCOCCUS AUREUS;

EID: 73949132404     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm900896h     Document Type: Article

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