Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men

Endocrinology

Volumn 152, Issue 12, 2011, Pages 4813-4824

  Thangavel, Chellappagounder ^a   Boopathi, Ettickan ^a   Shapiro, Bernard H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GROWTH HORMONE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LUCIFERASE; PREGNANE X RECEPTOR; RETINOID X RECEPTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; CELL STRAIN HEPG2; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA BINDING; FEMALE; GENE SILENCING; HORMONAL REGULATION; HORMONAL THERAPY; HUMAN; HUMAN CELL; LIVER CELL; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; SEX DIFFERENCE; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSIENT TRANSFECTION;

BIOLOGICAL TRANSPORT; CELLS, CULTURED; CYTOCHROME P-450 CYP3A; DEXAMETHASONE; GLUCOCORTICOIDS; GROWTH HORMONE; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; HUMAN GROWTH HORMONE; HUMANS; MALE; SEX CHARACTERISTICS; SEX FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 82355163418     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1274     Document Type: Article

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