The human drug metabolizing cytochromes P450

Journal of Pharmacokinetics and Biopharmaceutics

Volumn 24, Issue 5, 1996, Pages 461-473

  Wrighton, Steven A ^a   VandenBranden, Mark ^a   Ring, Barbara J ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Cytochrome P450; Drug metabolism; Hepatic; Human; In vitro models

Indexed keywords

4 METHYLPYRAZOLE; BARBITURIC ACID DERIVATIVE; CYTOCHROME P450; DEXAMETHASONE; DISULFIRAM; GESTODENE; ISONIAZID; MEPHENYTOIN; QUERCETIN; QUINIDINE; RETINOIC ACID; RIFAMPICIN; SULFAPHENAZOLE; TOLBUTAMIDE; TRANYLCYPROMINE; TROLEANDOMYCIN; ZATOSETRON;

DRUG CLEARANCE; DRUG DEVELOPMENT; DRUG INDUSTRY; DRUG METABOLISM; ENZYME ACTIVITY; HUMAN; LIVER MICROSOME; PHENOTYPE; PRIORITY JOURNAL; REVIEW;

BENZOFURANS; BICYCLO COMPOUNDS, HETEROCYCLIC; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DESIGN; ENZYME INDUCTION; HUMANS; LIVER; METABOLIC CLEARANCE RATE; MICROSOMES, LIVER; PHARMACEUTICAL PREPARATIONS; PHENOTYPE; SEROTONIN ANTAGONISTS; VARIATION (GENETICS);

EID: 0030428255     PISSN: 0090466X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02353474     Document Type: Review

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