메뉴 건너뛰기




Volumn 39, Issue 6, 2011, Pages 1710-1714

Cell autonomous and systemic factors in progeria development

Author keywords

Alternative splicing; Laminopathy; microRNA (miRNA); Progeria; Senescence; Tumour suppressor

Indexed keywords

BANF1 PROTEIN; MICRORNA; MICRORNA 29; NUCLEAR PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; ZINC METALLOPROTEASE STE24 HOMOLOGUE PROTEIN;

EID: 81855220930     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20110677     Document Type: Conference Paper
Times cited : (17)

References (58)
  • 1
    • 41649097238 scopus 로고    scopus 로고
    • Nuclear lamins: Major factors in the structural organization and function of the nucleus and chromatin
    • DOI 10.1101/gad.1652708
    • Dechat, T., Pfleghaar, K., Sengupta, K., Shimi, T., Shumaker, D.K., Solimando, L. and Goldman, R.D. (2008) Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. Genes Dev. 22, 832-853 (Pubitemid 351482836)
    • (2008) Genes and Development , vol.22 , Issue.7 , pp. 832-853
    • Dechat, T.1    Pfleghaar, K.2    Sengupta, K.3    Shimi, T.4    Shumaker, D.K.5    Solimando, L.6    Goldman, R.D.7
  • 2
    • 77951616674 scopus 로고    scopus 로고
    • The nuclear envelope in genome organization, expression and stability
    • Mekhail, K. and Moazed, D. (2010) The nuclear envelope in genome organization, expression and stability. Nat. Rev. Mol. Cell Biol. 11, 317-328
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 317-328
    • Mekhail, K.1    Moazed, D.2
  • 3
    • 76449089008 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport in yeast: A few roles for many actors
    • Fiserova, J. and Goldberg, M.W. (2010) Nucleocytoplasmic transport in yeast: a few roles for many actors. Biochem. Soc. Trans. 38, 273-277
    • (2010) Biochem. Soc. Trans. , vol.38 , pp. 273-277
    • Fiserova, J.1    Goldberg, M.W.2
  • 6
    • 33846484332 scopus 로고    scopus 로고
    • Human progeroid syndromes, aging and cancer: New genetic and epigenetic insights into old questions
    • DOI 10.1007/s00018-006-6349-3
    • Ramirez, C.L., Cadiñanos, J., Varela, I., Freije, J.M. and López-Otín, C. (2007) Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions. Cell. Mol. Life Sci. 64, 155-170 (Pubitemid 46156885)
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.2 , pp. 155-170
    • Ramirez, C.L.1    Cadinanos, J.2    Varela, I.3    Freije, J.M.P.4    Lopez-Otin, C.5
  • 7
    • 77954950116 scopus 로고    scopus 로고
    • Progeria syndromes and ageing: What is the connection?
    • Burtner, C.R. and Kennedy, B.K. (2010) Progeria syndromes and ageing: what is the connection? Nat. Rev. Mol. Cell Biol. 11, 567-578
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 567-578
    • Burtner, C.R.1    Kennedy, B.K.2
  • 8
    • 33845269544 scopus 로고    scopus 로고
    • Hutchinson-Gilford progeria syndrome: Review of the phenotype
    • Hennekam, R.C. (2006) Hutchinson-Gilford progeria syndrome: review of the phenotype. Am. J. Med. Genet. A 140, 2603-2624
    • (2006) Am. J. Med. Genet. A , vol.140 , pp. 2603-2624
    • Hennekam, R.C.1
  • 13
    • 0033564670 scopus 로고    scopus 로고
    • Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins
    • DOI 10.1006/geno.1999.5834
    • Freije, J.M., Blay, P., Pendás, A.M., Cadiñanos, J., Crespo, P. and López-Otín, C. (1999) Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins. Genomics 58, 270-280 (Pubitemid 29300310)
    • (1999) Genomics , vol.58 , Issue.3 , pp. 270-280
    • Freije, J.M.P.1    Blay, P.2    Pendas, A.M.3    Cadinanos, J.4    Crespo, P.5    Lopez-Otin, C.6
  • 18
    • 48049117058 scopus 로고    scopus 로고
    • Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: Effects on keratinocytes, hair and skin
    • Wang, Y., Panteleyev, A.A., Owens, D.M., Djabali, K., Stewart, C.L. and Worman, H.J. (2008) Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin. Hum. Mol. Genet. 17, 2357-2369
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 2357-2369
    • Wang, Y.1    Panteleyev, A.A.2    Owens, D.M.3    Djabali, K.4    Stewart, C.L.5    Worman, H.J.6
  • 19
    • 43149117884 scopus 로고    scopus 로고
    • Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease
    • DOI 10.1242/jcs.022913
    • Sagelius, H., Rosengardten, Y., Hanif, M., Erdos, M.R., Rozell, B., Collins, F.S. and Eriksson, M. (2008) Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease. J. Cell Sci. 121, 969-978 (Pubitemid 351639416)
    • (2008) Journal of Cell Science , vol.121 , Issue.7 , pp. 969-978
    • Sagelius, H.1    Rosengardten, Y.2    Hanif, M.3    Erdos, M.R.4    Rozell, B.5    Collins, F.S.6    Eriksson, M.7
  • 23
    • 68849119046 scopus 로고    scopus 로고
    • Laminopathies and the long strange trip from basic cell biology to therapy
    • Worman, H.J., Fong, L.G., Muchir, A. and Young, S.G. (2009) Laminopathies and the long strange trip from basic cell biology to therapy. J. Clin. Invest. 119, 1825-1836
    • (2009) J. Clin. Invest. , vol.119 , pp. 1825-1836
    • Worman, H.J.1    Fong, L.G.2    Muchir, A.3    Young, S.G.4
  • 25
    • 17644373758 scopus 로고    scopus 로고
    • Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
    • DOI 10.1038/nm1204
    • Scaffidi, P. and Misteli, T. (2005) Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat. Med. 11, 440-445 (Pubitemid 40562336)
    • (2005) Nature Medicine , vol.11 , Issue.4 , pp. 440-445
    • Scaffidi, P.1    Misteli, T.2
  • 27
    • 79959776029 scopus 로고    scopus 로고
    • Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
    • Cao, K., Graziotto, J.J., Blair, C.D., Mazzulli, J.R., Erdos, M.R., Krainc, D. and Collins, F.S. (2011) Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Sci. Transl. Med. 3, 89ra58
    • (2011) Sci. Transl. Med. , vol.3
    • Cao, K.1    Graziotto, J.J.2    Blair, C.D.3    Mazzulli, J.R.4    Erdos, M.R.5    Krainc, D.6    Collins, F.S.7
  • 28
    • 77957981121 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function
    • Mariño, G., Ugalde, A.P., Fernández, A.F., Osorio, F.G., Fueyo, A., Freije, J.M. and López-Otín, C. (2010) Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function. Proc. Natl. Acad. Sci. U.S.A. 107, 16268-16273
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 16268-16273
    • Mariño, G.1    Ugalde, A.P.2    Fernández, A.F.3    Osorio, F.G.4    Fueyo, A.5    Freije, J.M.6    López-Otín, C.7
  • 31
    • 13944262937 scopus 로고    scopus 로고
    • Understanding the odd science of aging
    • Kirkwood, T.B. (2005) Understanding the odd science of aging. Cell 120, 437-447
    • (2005) Cell , vol.120 , pp. 437-447
    • Kirkwood, T.B.1
  • 32
    • 79960046164 scopus 로고    scopus 로고
    • Cellular stress response pathways and ageing: Intricate molecular relationships
    • Kourtis, N. and Tavernarakis, N. (2011) Cellular stress response pathways and ageing: intricate molecular relationships. EMBO J. 30, 2520-2531
    • (2011) EMBO J. , vol.30 , pp. 2520-2531
    • Kourtis, N.1    Tavernarakis, N.2
  • 35
    • 29244437192 scopus 로고    scopus 로고
    • From immature lamin to premature aging: Molecular pathways and therapeutic opportunities
    • Cadiñanos, J., Varela, I., López-Otín, C. and Freije, J.M. (2005) From immature lamin to premature aging: molecular pathways and therapeutic opportunities. Cell Cycle 4, 1732-1735 (Pubitemid 41827315)
    • (2005) Cell Cycle , vol.4 , Issue.12 , pp. 1732-1735
    • Cadinanos, J.1    Varela, I.2    Lopez-Otin, C.3    Freije, J.M.P.4
  • 36
    • 43049128122 scopus 로고    scopus 로고
    • The type 2C phosphatase Wip1: An oncogenic regulator of tumour suppressor and DNA damage response pathways
    • Lu, X., Nguyen, T.A., Moon, S.H., Darlington, Y., Sommer, M. and Donehower, L.A. (2008) The type 2C phosphatase Wip1: an oncogenic regulator of tumour suppressor and DNA damage response pathways. Cancer Metastasis Rev. 27, 123-135
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 123-135
    • Lu, X.1    Nguyen, T.A.2    Moon, S.H.3    Darlington, Y.4    Sommer, M.5    Donehower, L.A.6
  • 38
    • 10944272639 scopus 로고    scopus 로고
    • Aging, tumour suppression and cancer: High wire-act!
    • Campisi, J. (2005) Aging, tumour suppression and cancer: high wire-act! Mech. Ageing Dev. 126, 51-58
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 51-58
    • Campisi, J.1
  • 39
  • 40
    • 68149169938 scopus 로고    scopus 로고
    • Signals of youth: Endocrine regulation of aging in Caenorhabditis elegans
    • Panowski, S.H. and Dillin, A. (2009) Signals of youth: endocrine regulation of aging in Caenorhabditis elegans. Trends Endocrinol. Metab. 20, 259-264
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 259-264
    • Panowski, S.H.1    Dillin, A.2
  • 41
    • 78649350746 scopus 로고    scopus 로고
    • The aging stress response
    • Haigis, M.C. and Yankner, B.A. (2010) The aging stress response. Mol. Cell 40, 333-344
    • (2010) Mol. Cell , vol.40 , pp. 333-344
    • Haigis, M.C.1    Yankner, B.A.2
  • 42
  • 44
    • 70349859881 scopus 로고    scopus 로고
    • DNA damage, aging, and cancer
    • Hoeijmakers, J.H. (2009) DNA damage, aging, and cancer. N. Engl. J. Med. 361, 1475-1485
    • (2009) N. Engl. J. Med. , vol.361 , pp. 1475-1485
    • Hoeijmakers, J.H.1
  • 45
    • 79952255626 scopus 로고    scopus 로고
    • Rejuvenating somatotropic signaling: A therapeutical opportunity for premature aging?
    • Ugalde, A.P., Marino, G. and López-Otín, C. (2010) Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging? Aging 2, 1017-1022
    • (2010) Aging , vol.2 , pp. 1017-1022
    • Ugalde, A.P.1    Marino, G.2    López-Otín, C.3
  • 46
    • 1642401437 scopus 로고    scopus 로고
    • Laron syndrome (primary growth hormone resistance or insensitivity): The personal experience 1958-2003
    • Laron, Z. (2004) Laron syndrome (primary growth hormone resistance or insensitivity): the personal experience 1958-2003. J. Clin. Endocrinol. Metab. 89, 1031-1044
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 1031-1044
    • Laron, Z.1
  • 47
    • 79953221503 scopus 로고    scopus 로고
    • Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies
    • Steuerman, R., Shevah, O. and Laron, Z. (2011) Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies. Eur. J. Endocrinol. 164, 485-489
    • (2011) Eur. J. Endocrinol. , vol.164 , pp. 485-489
    • Steuerman, R.1    Shevah, O.2    Laron, Z.3
  • 52
    • 2342463022 scopus 로고    scopus 로고
    • BAF: Roles in chromatin, nuclear structure and retrovirus integration
    • DOI 10.1016/j.tcb.2004.03.004, PII S0962892404000777
    • Segura-Totten, M. and Wilson, K.L. (2004) BAF: roles in chromatin, nuclear structure and retrovirus integration. Trends Cell Biol. 14, 261-266 (Pubitemid 38591330)
    • (2004) Trends in Cell Biology , vol.14 , Issue.5 , pp. 261-266
    • Segura-Totten, M.1    Wilson, K.L.2
  • 53
    • 33947715599 scopus 로고    scopus 로고
    • Barrier-to-autointegration factor - A BAFfling little protein
    • DOI 10.1016/j.tcb.2007.02.004, PII S0962892407000311
    • Margalit, A., Brachner, A., Gotzmann, J., Foisner, R. and Gruenbaum, Y. (2007) Barrier-to-autointegration factor: a BAFfling little protein. Trends Cell Biol. 17, 202-208 (Pubitemid 46507807)
    • (2007) Trends in Cell Biology , vol.17 , Issue.4 , pp. 202-208
    • Margalit, A.1    Brachner, A.2    Gotzmann, J.3    Foisner, R.4    Gruenbaum, Y.5
  • 54
    • 0036330001 scopus 로고    scopus 로고
    • Barrier-to-autointegration factor: Major roles in chromatin decondensation and nuclear assembly
    • DOI 10.1083/jcb.200202019
    • Segura-Totten, M., Kowalski, A.K., Craigie, R. and Wilson, K.L. (2002) Barrier-to-autointegration factor: major roles in chromatin decondensation and nuclear assembly. J. Cell Biol. 158, 475-485 (Pubitemid 34851706)
    • (2002) Journal of Cell Biology , vol.158 , Issue.3 , pp. 475-485
    • Segura-Totten, M.1    Kowalski, A.K.2    Craigie, R.3    Wilson, K.L.4
  • 55
    • 58349098943 scopus 로고    scopus 로고
    • Accelerated ageing: From mechanism to therapy through animal models
    • Osorio, F.G., Obaya, A.J., López-Otín, C. and Freije, J.M. (2009) Accelerated ageing: from mechanism to therapy through animal models. Transgenic Res. 18, 7-15
    • (2009) Transgenic Res. , vol.18 , pp. 7-15
    • Osorio, F.G.1    Obaya, A.J.2    López-Otín, C.3    Freije, J.M.4
  • 56
    • 33646745137 scopus 로고    scopus 로고
    • Lamin A-dependent nuclear defects in human aging
    • Scaffidi, P. and Misteli, T. (2006) Lamin A-dependent nuclear defects in human aging. Science 312, 1059-1063
    • (2006) Science , vol.312 , pp. 1059-1063
    • Scaffidi, P.1    Misteli, T.2
  • 57


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.