-
1
-
-
0026521412
-
Endoproteolytic processing of a farnesylated peptide in vitro
-
Ashby M. N., King D. S., Rine J. Endoproteolytic processing of a farnesylated peptide in vitro. Proc. Natl. Acad. Sci. USA. 89:1992;4613-4617.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4613-4617
-
-
Ashby, M.N.1
King, D.S.2
Rine, J.3
-
3
-
-
0031983131
-
A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis
-
Barrington R. E., Subler M. A., Rands E., Omer C. A., Miller P. J., Hundley J. E., Koester S. K., Troyer D. A., Bearss D. J., Conner M. W., Gibbs J. B., Hamilton K., Koblan K. S., Mosser S. D., O'Neill T. J., Schaber M. D., Senderak E. T., Windle J. J., Oliff A., Kohl N. E. A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Mol. Cell. Biol. 18:1998;85-92.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 85-92
-
-
Barrington, R.E.1
Subler, M.A.2
Rands, E.3
Omer, C.A.4
Miller, P.J.5
Hundley, J.E.6
Koester, S.K.7
Troyer, D.A.8
Bearss, D.J.9
Conner, M.W.10
Gibbs, J.B.11
Hamilton, K.12
Koblan, K.S.13
Mosser, S.D.14
O'Neill, T.J.15
Schaber, M.D.16
Senderak, E.T.17
Windle, J.J.18
Oliff, A.19
Kohl, N.E.20
more..
-
4
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos J. L. ras oncogenes in human cancer: A review. Cancer Res. 49:1989;4682-4689.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
5
-
-
0030909336
-
Modulation of Ras and a-factor function by carboxyl-terminal proteolysis
-
Boyartchuk V. L., Ashby M. N., Rine J. Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science. 275:1997;1796-1800.
-
(1997)
Science
, vol.275
, pp. 1796-1800
-
-
Boyartchuk, V.L.1
Ashby, M.N.2
Rine, J.3
-
6
-
-
0029990398
-
Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease
-
Chen Y., Ma Y. T., Rando R. R. Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease. Biochemistry. 35:1996;3227-3237.
-
(1996)
Biochemistry
, vol.35
, pp. 3227-3237
-
-
Chen, Y.1
Ma, Y.T.2
Rando, R.R.3
-
7
-
-
0026735063
-
Protein isoprenylation and methylation at carboxyl-terminal cysteine residues
-
Clarke S. Protein isoprenylation and methylation at carboxyl-terminal cysteine residues. Annu. Rev. Biochem. 61:1992;355-386.
-
(1992)
Annu. Rev. Biochem.
, vol.61
, pp. 355-386
-
-
Clarke, S.1
-
8
-
-
0032511057
-
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
-
Dai Q., Choy E., Chiu V., Romano J., Slivka S. R., Steitz S. A., Michaelis S., Philips M. R. Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum. J. Biol. Chem. 273:1998;15030-15034.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15030-15034
-
-
Dai, Q.1
Choy, E.2
Chiu, V.3
Romano, J.4
Slivka, S.R.5
Steitz, S.A.6
Michaelis, S.7
Philips, M.R.8
-
9
-
-
0021760092
-
A comprehensive set of sequence analysis programs for the VAX
-
Devereux J., Haeberli P., Smithies O. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:1984;387-395.
-
(1984)
Nucleic Acids Res.
, vol.12
, pp. 387-395
-
-
Devereux, J.1
Haeberli, P.2
Smithies, O.3
-
11
-
-
9044240048
-
A radiation hybrid map of the human genome
-
Gyapay G., Schmitt K., Fizames C., Jones H., Vega Czarny N., Spillett D., Muselet D., PrudHomme J. F., Dib C., Auffray C., Morissette J., Weissenbach J., Goodfellow P. N. A radiation hybrid map of the human genome. Hum. Mol. Genet. 5:1996;339-346.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 339-346
-
-
Gyapay, G.1
Schmitt, K.2
Fizames, C.3
Jones, H.4
Vega Czarny, N.5
Spillett, D.6
Muselet, D.7
Prudhomme, J.F.8
Dib, C.9
Auffray, C.10
Morissette, J.11
Weissenbach, J.12
Goodfellow, P.N.13
-
12
-
-
0026021456
-
Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B)
-
Hancock J. F., Cadwallader K., Marshall C. J. Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B). EMBO J. 10:1991;641-646.
-
(1991)
EMBO J.
, vol.10
, pp. 641-646
-
-
Hancock, J.F.1
Cadwallader, K.2
Marshall, C.J.3
-
13
-
-
0027941838
-
Families of zinc metalloproteases
-
Hooper N. M. Families of zinc metalloproteases. FEBS Lett. 354:1994;1-6.
-
(1994)
FEBS Lett.
, vol.354
, pp. 1-6
-
-
Hooper, N.M.1
-
14
-
-
0026779707
-
Maturation of isoprenylated proteins in Saccharomyces cerevisiae: Multiple activities catalyze the cleavage of the three carboxyl-terminal amino acids from farnesylated substrates in vitro
-
Hrycyna C. A., Clarke S. Maturation of isoprenylated proteins in Saccharomyces cerevisiae: Multiple activities catalyze the cleavage of the three carboxyl-terminal amino acids from farnesylated substrates in vitro. J. Biol. Chem. 267:1992;10457-10464.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 10457-10464
-
-
Hrycyna, C.A.1
Clarke, S.2
-
15
-
-
0032584323
-
Substrate specificity of mammalian prenyl protein-specific endoprotease activity
-
Jang G. F., Gelb M. H. Substrate specificity of mammalian prenyl protein-specific endoprotease activity. Biochemistry. 37:1998;4473-4481.
-
(1998)
Biochemistry
, vol.37
, pp. 4473-4481
-
-
Jang, G.F.1
Gelb, M.H.2
-
16
-
-
0027527703
-
A prenylated protein-specific endoprotease in rat liver microsomes that produces a carboxyl-terminal tripeptide
-
Jang G. F., Yokoyama K., Gelb M. H. A prenylated protein-specific endoprotease in rat liver microsomes that produces a carboxyl-terminal tripeptide. Biochemistry. 32:1993;9500-9507.
-
(1993)
Biochemistry
, vol.32
, pp. 9500-9507
-
-
Jang, G.F.1
Yokoyama, K.2
Gelb, M.H.3
-
17
-
-
0031050738
-
Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment
-
Lebowitz P. F., Sakamuro D., Prendergast G. C. Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment. Cancer Res. 57:1997;708-713.
-
(1997)
Cancer Res.
, vol.57
, pp. 708-713
-
-
Lebowitz, P.F.1
Sakamuro, D.2
Prendergast, G.C.3
-
18
-
-
0030952552
-
Inhibition of the prenylation of K-Ras, but not H- Or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines
-
Lerner E. C., Zhang T. T., Knowles D. B., Qian Y., Hamilton A. D., Sebti S. M. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines. Oncogene. 15:1997;1283-1288.
-
(1997)
Oncogene
, vol.15
, pp. 1283-1288
-
-
Lerner, E.C.1
Zhang, T.T.2
Knowles, D.B.3
Qian, Y.4
Hamilton, A.D.5
Sebti, S.M.6
-
20
-
-
0026680433
-
A microsomal endoprotease that specifically cleaves isoprenylated peptides
-
Ma Y. T., Rando R. R. A microsomal endoprotease that specifically cleaves isoprenylated peptides. Proc. Natl. Acad. Sci. USA. 89:1992;6275-6279.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6275-6279
-
-
Ma, Y.T.1
Rando, R.R.2
-
21
-
-
0032521211
-
Antitumor effect of a farnesyl protein transferase inhibitor in mammary and lymphoid tumors overexpressing N-ras in transgenic mice
-
Mangues R., Corral T., Kohl N. E., Symmans W. F., Lu S., Malumbres M., Gibbs J. B., Oliff A., Pellicer A. Antitumor effect of a farnesyl protein transferase inhibitor in mammary and lymphoid tumors overexpressing N-ras in transgenic mice. Cancer Res. 58:1998;1253-1259.
-
(1998)
Cancer Res.
, vol.58
, pp. 1253-1259
-
-
Mangues, R.1
Corral, T.2
Kohl, N.E.3
Symmans, W.F.4
Lu, S.5
Malumbres, M.6
Gibbs, J.B.7
Oliff, A.8
Pellicer, A.9
-
22
-
-
0030999555
-
A breakpoint map of recurrent chromosomal rearrangements in human neoplasia
-
Mitelman F., Mertens F., Johansson B. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nature Genet. 15:1997;417-474.
-
(1997)
Nature Genet.
, vol.15
, pp. 417-474
-
-
Mitelman, F.1
Mertens, F.2
Johansson, B.3
-
23
-
-
0028178289
-
Mapping of the human Zn-alpha 2-glycoprotein gene (AZGP1) to chromosome 7q22 by in situ hybridization
-
Pendás A. M., Matilla T., Uría J. A., Freije J. P., Fueyo A., Estivill X., López-Otín C. Mapping of the human Zn-alpha 2-glycoprotein gene (AZGP1) to chromosome 7q22 by in situ hybridization. Cytogenet. Cell Genet. 66:1994;263-266.
-
(1994)
Cytogenet. Cell Genet.
, vol.66
, pp. 263-266
-
-
Pendás, A.M.1
Matilla, T.2
Uría, J.A.3
Freije, J.P.4
Fueyo, A.5
Estivill, X.6
López-Otín, C.7
-
24
-
-
0029036451
-
Evolutionary families of metallopeptidases
-
Rawlings N. D., Barrett A. J. Evolutionary families of metallopeptidases. Methods Enzymol. 248:1995;183-228.
-
(1995)
Methods Enzymol.
, vol.248
, pp. 183-228
-
-
Rawlings, N.D.1
Barrett, A.J.2
-
25
-
-
0031301274
-
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
-
Rawson R. B., Zelenski N. G., Nijhawan D., Ye J., Sakai J., Hasan M. T., Chang T. Y., Brown M. S., Goldstein J. L. Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs. Mol. Cell. 1:1997;47-57.
-
(1997)
Mol. Cell
, vol.1
, pp. 47-57
-
-
Rawson, R.B.1
Zelenski, N.G.2
Nijhawan, D.3
Ye, J.4
Sakai, J.5
Hasan, M.T.6
Chang, T.Y.7
Brown, M.S.8
Goldstein, J.L.9
-
26
-
-
0028125792
-
Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export
-
Sapperstein S., Berkower C., Michaelis S. Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export. Mol. Cell. Biol. 14:1994;1438-1449.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1438-1449
-
-
Sapperstein, S.1
Berkower, C.2
Michaelis, S.3
-
27
-
-
0026744608
-
Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer
-
Schuuring E., Verhoeven E., van Tinteren H., Peterse J. L., Nunnink B., Thunnissen F. B., Devilee P., Cornelisse C. J., van de Vijver M. J., Mooi W. J., Rob J. A., Michalides J. A. M. Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer. Cancer Res. 52:1992;5229-5234.
-
(1992)
Cancer Res.
, vol.52
, pp. 5229-5234
-
-
Schuuring, E.1
Verhoeven, E.2
Van Tinteren, H.3
Peterse, J.L.4
Nunnink, B.5
Thunnissen, F.B.6
Devilee, P.7
Cornelisse, C.J.8
Van De Vijver, M.J.9
Mooi, W.J.10
Rob, J.A.11
Michalides, J.A.M.12
-
28
-
-
0029795076
-
The gene for Schnyder's crystalline corneal dystrophy maps to human chromosome 1p34.1-p36
-
Shearman A. M., Hudson T. J., Andresen J. M., Wu X., Sohn R. L., Haluska F., Housman D. E., Weiss J. S. The gene for Schnyder's crystalline corneal dystrophy maps to human chromosome 1p34.1-p36. Hum. Mol. Genet. 5:1996;1667-1672.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1667-1672
-
-
Shearman, A.M.1
Hudson, T.J.2
Andresen, J.M.3
Wu, X.4
Sohn, R.L.5
Haluska, F.6
Housman, D.E.7
Weiss, J.S.8
-
30
-
-
0024344940
-
Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: Hst-1/int-2 and c-erbB-2/ear-1
-
Tsuda H., Hirohashi S., Shimosato Y., Hirota T., Tsugane S., Yamamoto H., Miyajima N., Toyoshima K., Yamamoto T., Yokota J., Yoshida T., Sakamoto H., Terada M., Sugimura T. Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1. Cancer Res. 49:1989;3104-3108.
-
(1989)
Cancer Res.
, vol.49
, pp. 3104-3108
-
-
Tsuda, H.1
Hirohashi, S.2
Shimosato, Y.3
Hirota, T.4
Tsugane, S.5
Yamamoto, H.6
Miyajima, N.7
Toyoshima, K.8
Yamamoto, T.9
Yokota, J.10
Yoshida, T.11
Sakamoto, H.12
Terada, M.13
Sugimura, T.14
-
31
-
-
0031127215
-
Linkage analysis of progressive hearing loss in five extended families maps the DFNA2 gene to a 1.25-Mb region on chromosome 1p
-
Van Camp G., Coucke P. J., Kunst H., Schatteman I., Van Velzen D., Marres H., van Ewijk M., Declau F., Van Hauwe P., Meyers J., Kenyon J., Smith S. D., Smith R. J., Djelantik B., Cremers C. W., Van de Heyning P. H., Willems P. J. Linkage analysis of progressive hearing loss in five extended families maps the DFNA2 gene to a 1.25-Mb region on chromosome 1p. Genomics. 41:1997;70-74.
-
(1997)
Genomics
, vol.41
, pp. 70-74
-
-
Van Camp, G.1
Coucke, P.J.2
Kunst, H.3
Schatteman, I.4
Van Velzen, D.5
Marres, H.6
Van Ewijk, M.7
Declau, F.8
Van Hauwe, P.9
Meyers, J.10
Kenyon, J.11
Smith, S.D.12
Smith, R.J.13
Djelantik, B.14
Cremers, C.W.15
Van De Heyning, P.H.16
Willems, P.J.17
-
32
-
-
0031002660
-
The redistribution of cortactin into cell-matrix contact sites in human carcinoma cells with 11q13 amplification is associated with both overexpression and post-translational modification
-
Van Damme H., Brok H., Schuuring-Scholtes E., Schuuring E. The redistribution of cortactin into cell-matrix contact sites in human carcinoma cells with 11q13 amplification is associated with both overexpression and post-translational modification. J. Biol. Chem. 272:1997;7374-7380.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7374-7380
-
-
Van Damme, H.1
Brok, H.2
Schuuring-Scholtes, E.3
Schuuring, E.4
-
33
-
-
0027970068
-
Identification of two active site residues in human angiotensin I-converting enzyme
-
Williams T. A., Corvol P., Soubrier F. Identification of two active site residues in human angiotensin I-converting enzyme. J. Biol. Chem. 269:1994;29430-29434.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29430-29434
-
-
Williams, T.A.1
Corvol, P.2
Soubrier, F.3
-
34
-
-
0029898894
-
Protein prenylation: Molecular mechanisms and functional consequences
-
Zhang F. L., Casey P. J. Protein prenylation: Molecular mechanisms and functional consequences. Annu. Rev. Biochem. 65:1996;241-269.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 241-269
-
-
Zhang, F.L.1
Casey, P.J.2
|