메뉴 건너뛰기




Volumn 12, Issue 5, 2010, Pages 415-424

Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of β-catenin-dependent signaling

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; CYCLIN C; CYCLIN D1; CYCLIN DEPENDENT KINASE 8; CYCLINE; MYC PROTEIN; SILIBININ; T CELL FACTOR PROTEIN; T CELL FACTOR PROTEIN 4; UNCLASSIFIED DRUG;

EID: 77951679964     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.10188     Document Type: Article
Times cited : (95)

References (49)
  • 3
    • 36049020580 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1975-2004, featuring cancer in American Indians and Alaska Natives
    • Espey DK, Wu XC, Swan J, Wiggins C, Jim MA, Ward E, Wingo PA, Howe HL, Ries LA, Miller BA, et al. (2007). Annual report to the nation on the status of cancer, 1975-2004, featuring cancer in American Indians and Alaska Natives. Cancer 110, 2119-2152.
    • (2007) Cancer , vol.110 , pp. 2119-2152
    • Espey, D.K.1    Wu, X.C.2    Swan, J.3    Wiggins, C.4    Jim, M.A.5    Ward, E.6    Wingo, P.A.7    Howe, H.L.8    Ries, L.A.9    Miller, B.A.10
  • 4
    • 58849129818 scopus 로고    scopus 로고
    • Colorectal cancer: A summary of the evidence for screening and prevention
    • Wilkins T and Reynolds PL (2008). Colorectal cancer: a summary of the evidence for screening and prevention. Am Fam Physician 78, 1385-1392.
    • (2008) Am Fam Physician , vol.78 , pp. 1385-1392
    • Wilkins, T.1    Reynolds, P.L.2
  • 5
    • 65649106947 scopus 로고    scopus 로고
    • Colon cancer: Preventive agents and the present status of chemoprevention
    • Half E and Arber N (2009). Colon cancer: preventive agents and the present status of chemoprevention. Expert Opin Pharmacother 10, 211-219.
    • (2009) Expert Opin Pharmacother , vol.10 , pp. 211-219
    • Half, E.1    Arber, N.2
  • 6
    • 26944502030 scopus 로고    scopus 로고
    • Colorectal cancer: Lifestyle and dietary factors
    • Corrêa Lima MP and Gomes-da-Silva MH (2005). Colorectal cancer: lifestyle and dietary factors. Nutr Hosp 20, 235-241.
    • (2005) Nutr Hosp , vol.20 , pp. 235-241
    • Corrêa Lima, M.P.1    Gomes-da-Silva, M.H.2
  • 7
    • 58149463602 scopus 로고    scopus 로고
    • Lifestyle, genes, and cancer
    • Coyle YM (2009). Lifestyle, genes, and cancer. Methods Mol Biol 472, 25-56.
    • (2009) Methods Mol Biol , vol.472 , pp. 25-56
    • Coyle, Y.M.1
  • 10
    • 36849016287 scopus 로고    scopus 로고
    • Fruit and vegetable intake and prevalence of colorectal adenoma in a cancer screening trial
    • PLCO Cancer Screening Trial Project Team
    • Millen AF, Subar AF, Graubard BI, Peters U, Hayes RB, Weissfeld JL, Yokochi LA, Ziegler RG, and PLCO Cancer Screening Trial Project Team (2007). Fruit and vegetable intake and prevalence of colorectal adenoma in a cancer screening trial. Am J Clin Nutr 86, 1754-1764.
    • (2007) Am J Clin Nutr , vol.86 , pp. 1754-1764
    • Millen, A.F.1    Subar, A.F.2    Graubard, B.I.3    Peters, U.4    Hayes, R.B.5    Weissfeld, J.L.6    Yokochi, L.A.7    Ziegler, R.G.8
  • 11
    • 58149247844 scopus 로고    scopus 로고
    • Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis
    • Mann CD, Neal CP, Garcea G, Manson MM, Dennison AR, and Berry DP (2009). Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis. Eur J Cancer Prev 18, 13-25.
    • (2009) Eur J Cancer Prev , vol.18 , pp. 13-25
    • Mann, C.D.1    Neal, C.P.2    Garcea, G.3    Manson, M.M.4    Dennison, A.R.5    Berry, D.P.6
  • 12
    • 56249107263 scopus 로고    scopus 로고
    • Dietary cancer chemopreventive agents-targeting inflammation and Nrf2 signaling pathway
    • Khor TO, Yu S, and Kong AN (2008). Dietary cancer chemopreventive agents-targeting inflammation and Nrf2 signaling pathway. Planta Med 74, 1540-1547.
    • (2008) Planta Med , vol.74 , pp. 1540-1547
    • Khor, T.O.1    Yu, S.2    Kong, A.N.3
  • 13
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ (2003). Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3, 768-780.
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 14
    • 33750719426 scopus 로고    scopus 로고
    • Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells
    • Kaur M, Singh RP, Gu M, Agarwal R, and Agarwal C (2006). Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells. Clin Cancer Res 12, 6194-6202.
    • (2006) Clin Cancer Res , vol.12 , pp. 6194-6202
    • Kaur, M.1    Singh, R.P.2    Gu, M.3    Agarwal, R.4    Agarwal, C.5
  • 15
    • 61549128686 scopus 로고    scopus 로고
    • Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats
    • Velmurugan B, Singh RP, Tyagi A, and Agarwal R (2008). Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats. Cancer Prev Res (Phila Pa) 1, 376-384.
    • (2008) Cancer Prev Res (Phila Pa) , vol.1 , pp. 376-384
    • Velmurugan, B.1    Singh, R.P.2    Tyagi, A.3    Agarwal, R.4
  • 16
    • 40949106128 scopus 로고    scopus 로고
    • Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis
    • Singh RP, Gu M, and Agarwal R (2008). Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis. Cancer Res 68, 2043-2050.
    • (2008) Cancer Res , vol.68 , pp. 2043-2050
    • Singh, R.P.1    Gu, M.2    Agarwal, R.3
  • 17
    • 33745002041 scopus 로고    scopus 로고
    • Prostate cancer chemoprevention by silibinin: Bench to bedside
    • Singh RP and Agarwal R (2006). Prostate cancer chemoprevention by silibinin: bench to bedside. Mol Carcinog 45, 436-442.
    • (2006) Mol Carcinog , vol.45 , pp. 436-442
    • Singh, R.P.1    Agarwal, R.2
  • 18
    • 27644439523 scopus 로고    scopus 로고
    • Mechanisms and preclinical efficacy of silibinin in preventing skin cancer
    • Singh RPand Agarwal R (2005). Mechanisms and preclinical efficacy of silibinin in preventing skin cancer. Eur J Cancer 41, 1969-1979.
    • (2005) Eur J Cancer , vol.41 , pp. 1969-1979
    • Singh, R.P.1    Agarwal, R.2
  • 19
    • 0344827261 scopus 로고    scopus 로고
    • Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells
    • Agarwal C, Singh RP, Dhanalakshmi S, Tyagi AK, Tecklenburg M, Sclafani RA, and Agarwal R (2003). Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene 22, 8271-8282.
    • (2003) Oncogene , vol.22 , pp. 8271-8282
    • Agarwal, C.1    Singh, R.P.2    Dhanalakshmi, S.3    Tyagi, A.K.4    Tecklenburg, M.5    Sclafani, R.A.6    Agarwal, R.7
  • 20
    • 37549017366 scopus 로고    scopus 로고
    • Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice
    • Tyagi A, Raina K, Singh RP, Gu M, Agarwal C, Harrison G, Glode LM, and Agarwal R (2007). Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Mol Cancer Ther 6, 3248-3255.
    • (2007) Mol Cancer Ther , vol.6 , pp. 3248-3255
    • Tyagi, A.1    Raina, K.2    Singh, R.P.3    Gu, M.4    Agarwal, C.5    Harrison, G.6    Glode, L.M.7    Agarwal, R.8
  • 21
    • 36348976518 scopus 로고    scopus 로고
    • Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model
    • Raina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, et al. (2007). Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model. Cancer Res 67, 11083-11091.
    • (2007) Cancer Res , vol.67 , pp. 11083-11091
    • Raina, K.1    Blouin, M.J.2    Singh, R.P.3    Majeed, N.4    Deep, G.5    Varghese, L.6    Glodé, L.M.7    Greenberg, N.M.8    Hwang, D.9    Cohen, P.10
  • 24
    • 0035797897 scopus 로고    scopus 로고
    • Adhesion signaling: How β-catenin interacts with its partners
    • Gottardi CJ and Gumbiner BM (2001). Adhesion signaling: how β-catenin interacts with its partners. Curr Biol 11, R792-R794.
    • (2001) Curr Biol , vol.11
    • Gottardi, C.J.1    Gumbiner, B.M.2
  • 25
    • 58749097656 scopus 로고    scopus 로고
    • The canonical Wnt/β-catenin signalling pathway
    • Barker NV (2008). The canonical Wnt/β-catenin signalling pathway. Methods Mol Biol 468, 5-15.
    • (2008) Methods Mol Biol , vol.468 , pp. 5-15
    • Barker, N.V.1
  • 26
    • 49049107812 scopus 로고    scopus 로고
    • An oncogenic hub: β-catenin as a molecular target for cancer therapeutics
    • Takemaru KI, Ohmitsu M, and Li FQ (2008). An oncogenic hub: β-catenin as a molecular target for cancer therapeutics. Handb Exp Pharmacol 186, 261-284.
    • (2008) Handb Exp Pharmacol , vol.186 , pp. 261-284
    • Takemaru, K.I.1    Ohmitsu, M.2    Li, F.Q.3
  • 27
    • 0036224749 scopus 로고    scopus 로고
    • The APC gene in colorectal cancer
    • Fodde R (2002). The APC gene in colorectal cancer. Eur J Cancer 38, 867-871.
    • (2002) Eur J Cancer , vol.38 , pp. 867-871
    • Fodde, R.1
  • 31
    • 0037034863 scopus 로고    scopus 로고
    • Silibinin inhibits constitutiveand TNFα-induced activationofNF-κBand sensitizes human prostate carcinoma DU145 cells to TNFα-induced apoptosis
    • Dhanalakshmi S, Singh RP, Agarwal C, and Agarwal R (2002). Silibinin inhibits constitutiveand TNFα-induced activationofNF-κBand sensitizes human prostate carcinoma DU145 cells to TNFα-induced apoptosis. Oncogene 21, 1759-1767.
    • (2002) Oncogene , vol.21 , pp. 1759-1767
    • Dhanalakshmi, S.1    Singh, R.P.2    Agarwal, C.3    Agarwal, R.4
  • 33
    • 20144372639 scopus 로고    scopus 로고
    • Milk thistle and prostate cancer: Differential effects of pure flavonolignans from Silybum marianum on anti-proliferative end points in human prostate carcinoma cells
    • Davis-Searles PR, Nakanishi Y, Kim NC, Graf TN, Oberlies NH, Wani MC, Wall ME, Agarwal R, and Kroll DJ (2005). Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on anti-proliferative end points in human prostate carcinoma cells. Cancer Res 65, 4448-4457.
    • (2005) Cancer Res , vol.65 , pp. 4448-4457
    • Davis-Searles, P.R.1    Nakanishi, Y.2    Kim, N.C.3    Graf, T.N.4    Oberlies, N.H.5    Wani, M.C.6    Wall, M.E.7    Agarwal, R.8    Kroll, D.J.9
  • 34
    • 0032239998 scopus 로고    scopus 로고
    • A review of plants used in the treatment of liver disease: Part 1
    • Luper S (1998). A review of plants used in the treatment of liver disease: part 1. Altern Med Rev 3, 410-421.
    • (1998) Altern Med Rev , vol.3 , pp. 410-421
    • Luper, S.1
  • 35
    • 33847397617 scopus 로고    scopus 로고
    • The canonical Wnt signalling pathway and its APC partner in colon cancer development
    • Schneikert J and Behrens J (2007). The canonical Wnt signalling pathway and its APC partner in colon cancer development. Gut 56, 417-425.
    • (2007) Gut , vol.56 , pp. 417-425
    • Schneikert, J.1    Behrens, J.2
  • 36
    • 33845351956 scopus 로고    scopus 로고
    • β-Catenin destruction complex: Insights and questions from a structural perspective
    • Kimelman D and Xu W (2006). β-Catenin destruction complex: insights and questions from a structural perspective. Oncogene 25, 7482-7491.
    • (2006) Oncogene , vol.25 , pp. 7482-7491
    • Kimelman, D.1    Xu, W.2
  • 37
    • 0035947083 scopus 로고    scopus 로고
    • Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein
    • Liu J, Stevens J, Rote CA, Yost HJ, Hu Y, Neufeld KL, White RL, and Matsunami N (2001). Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol Cell 7, 927-936.
    • (2001) Mol Cell , vol.7 , pp. 927-936
    • Liu, J.1    Stevens, J.2    Rote, C.A.3    Yost, H.J.4    Hu, Y.5    Neufeld, K.L.6    White, R.L.7    Matsunami, N.8
  • 38
    • 34247267659 scopus 로고    scopus 로고
    • Retinol decreases β-catenin protein levels in retinoic acid-resistant colon cancer cell lines
    • Dillard AC and Lane MA (2007). Retinol decreases β-catenin protein levels in retinoic acid-resistant colon cancer cell lines. Mol Carcinog 46, 315-329.
    • (2007) Mol Carcinog , vol.46 , pp. 315-329
    • Dillard, A.C.1    Lane, M.A.2
  • 39
    • 0027146559 scopus 로고
    • Mutations of the APC (adenomatous polyposis coli) gene
    • Nagase H and Nakamura Y (1993). Mutations of the APC (adenomatous polyposis coli) gene. Hum Mutat 2, 425-434.
    • (1993) Hum Mutat , vol.2 , pp. 425-434
    • Nagase, H.1    Nakamura, Y.2
  • 40
    • 0030948623 scopus 로고    scopus 로고
    • The APC tumor suppressor protein in development and cancer
    • Moon RT and Miller JR (1997). The APC tumor suppressor protein in development and cancer. Trends Genet 13, 256-258.
    • (1997) Trends Genet , vol.13 , pp. 256-258
    • Moon, R.T.1    Miller, J.R.2
  • 43
    • 0033913603 scopus 로고    scopus 로고
    • Control of β-catenin signaling in tumor development
    • Behrens J (2000). Control of β-catenin signaling in tumor development. Ann N Y Acad Sci 910, 21-33.
    • (2000) Ann N Y Acad Sci , vol.910 , pp. 21-33
    • Behrens, J.1
  • 44
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: Cyclin D1: Normal and abnormal functions
    • Fu M, Wang C, Li Z, Sakamaki T, and Pestell RG (2004). Minireview: cyclin D1: normal and abnormal functions. Endocrinology 145, 5439-5447.
    • (2004) Endocrinology , vol.145 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 46
    • 48549099080 scopus 로고    scopus 로고
    • C-Myc is a critical mediator of the phenotypes of APC loss in the intestine
    • Wilkins JA and Sansom OJ (2008). C-Myc is a critical mediator of the phenotypes of APC loss in the intestine. Cancer Res 68, 4963-4966.
    • (2008) Cancer Res , vol.68 , pp. 4963-4966
    • Wilkins, J.A.1    Sansom, O.J.2
  • 48
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • Reagan-Shaw S, Nihal M, and Ahmad N (2008). Dose translation from animal to human studies revisited. FASEB J 22, 659-661.
    • (2008) FASEB J , vol.22 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 49
    • 33646739493 scopus 로고    scopus 로고
    • Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: Silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences
    • Hoh C, Boocock D, Marczylo T, Singh R, Berry DP, Dennison AR, Hemingway D, Miller A, West K, Euden S, et al. (2006). Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences. Clin Cancer Res 12, 2944-2950.
    • (2006) Clin Cancer Res , vol.12 , pp. 2944-2950
    • Hoh, C.1    Boocock, D.2    Marczylo, T.3    Singh, R.4    Berry, D.P.5    Dennison, A.R.6    Hemingway, D.7    Miller, A.8    West, K.9    Euden, S.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.