Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?

FEBS Letters

Volumn 585, Issue 23, 2011, Pages 3689-3698

  Burn, Garth L ^a   Svensson, Lena ^a   Sanchez Blanco, Cristina ^a   Saini, Manoj ^a   Cope, Andrew P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Autoimmunity; Genetics; Lyp; Phosphatase; PTPN22

Indexed keywords

ARGININE; ISOPROTEIN; MUTANT PROTEIN; PROLINE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR; TRYPTOPHAN;

ADDISON DISEASE; AMINO ACID SUBSTITUTION; AUTOIMMUNE DISEASE; AUTOIMMUNITY; B LYMPHOCYTE; DISEASE ACTIVITY; ENZYME ACTIVITY; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; GRAVES DISEASE; HASHIMOTO DISEASE; HETEROZYGOTE; HLA SYSTEM; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOPATHOGENESIS; INSULIN DEPENDENT DIABETES MELLITUS; JUVENILE RHEUMATOID ARTHRITIS; MYASTHENIA GRAVIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PSORIATIC ARTHRITIS; PTPN22 GENE; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS; T LYMPHOCYTE; VITILIGO;

ANIMALS; AUTOIMMUNE DISEASES; AUTOIMMUNITY; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MUTANT PROTEINS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22;

EID: 81755179431     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.04.032     Document Type: Review

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