Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 5, 1997, Pages 1680-1685

  Flint, Andrew J ^a,c   Tiganis, Tony ^a   Barford, David ^b   Tonks, Nicholas K ^a  

^a Watson School of Biological Sciences   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Charybdis Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MUTANT PROTEIN; PROTEIN TYROSINE PHOSPHATASE; VANADIC ACID;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BINDING SITE; CELL LINE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ASPARTIC ACID; BINDING SITES; BINDING, COMPETITIVE; BLOTTING, WESTERN; CELLS, CULTURED; COS CELLS; EPIDERMAL GROWTH FACTOR; HUMANS; KINETICS; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; PHOSPHOTYROSINE; PLATELET-DERIVED GROWTH FACTOR; POINT MUTATION; PROTEIN BINDING; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SUBSTRATE SPECIFICITY; TRANSFECTION;

ANIMALIA;

EID: 0031055324     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.5.1680     Document Type: Article

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