Down-regulation of shadoo in prion infections traces a pre-clinical event inversely related to PrP sc accumulation

PLoS Pathogens

Volumn 7, Issue 11, 2011, Pages

  Westaway, David ^a,b   Genovesi, Sacha ^a   Daude, Nathalie ^a   Brown, Rebecca ^c   Lau, Agnes ^a   Lee, Inyoul ^d   Mays, Charles E ^a   Coomaraswamy, Janaky ^e   Canine, Brenda ^c   Pitstick, Rose ^c   Herbst, Allen ^a   Yang, Jing ^a   Ko, Kerry W S ^a   Schmitt Ulms, Gerold ^f,g   DeArmond, Stephen J ^h   McKenzie, Debbie ^a   Hood, Leroy ^d   Carlson, George A ^c  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c MCLAUGHLIN RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e UNIVERSITY OF TÜBINGEN   (Germany)

^f UNIVERSITY OF TORONTO   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAN AMYLOID PEPTIDE; AMYLOID PROTEIN; CUPRIZONE; GLYCOPROTEIN; MESSENGER RNA; PRION PROTEIN; PROTEINASE; SHADOO PROTEIN; SPRN PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; NERVE PROTEIN; SHADOO PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATION; DEMENTIA; EXTRACELLULAR MATRIX; GENE EXPRESSION; HISTOPATHOLOGY; HOMOZYGOSITY; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVE CELL LESION; NONHUMAN; PRION; PRION DISEASE; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TAUOPATHY; TRANSGENE; VIRUS GENE; VIRUS STRAIN; ANIMAL; BIOSYNTHESIS; BRAIN; DOWN REGULATION; GENETICS; METABOLISM; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS; RODENTIA;

ANIMALS; BRAIN; DOWN-REGULATION; GPI-LINKED PROTEINS; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; PRION DISEASES; PRPC PROTEINS; PRPSC PROTEINS; RNA, MESSENGER;

EID: 81755177709     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002391     Document Type: Article

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