Comparative prion disease gene expression profiling using the prion disease mimetic, cuprizone

Prion

Volumn 3, Issue 2, 2009, Pages 99-109

  Moody, Laura R ^a   Herbst, Allen J ^a,b   Han, Sang Yoo ^c   Vanderloo, Joshua P ^a   Aiken, Judd M ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c Seoul National University   (South Korea)

Author keywords

Comparative profiling; Cuprizone; Gene expression; Microarray; RML infection

Indexed keywords

CUPRIZONE; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN TISSUE; CELL POPULATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; MICROANALYSIS; MOUSE; NONHUMAN; PRION DISEASE; TRANSCRIPTION INITIATION; UPREGULATION;

ANIMALIA; MUS;

EID: 67649352679     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.3.2.9059     Document Type: Article

References (47)

1. Collinge J. Prion diseases of humans and animals: Their causes and molecular basis. Annu Rev Neurosci 2001; 24:519-550 (Pubitemid 32695238)
2. Duguid JR, Rohwer RG, Seed B. Isolation of cDNAs of scrapie-modulated RNAs by subtractive hybridization of a cDNA library. Proc Natl Acad Sci USA 1988; 85:5738-5742 (Pubitemid 18207110)
3. Duguid JR, Bohmont CW, Liu NG, Tourtellotte WW. Changes in brain gene expression shared by scrapie and alzheimer disease. Proc Natl Acad Sci USA 1989; 86:7260-7264 (Pubitemid 19240906)
4. Duguid JR, Dinauer MC. Library subtraction of in vitro cDNA libraries to identify differentially expressed genes in scrapie infection. Nucleic Acids Res 1990; 18:2789-2792 (Pubitemid 20150630)
5. Diedrich JF, Minnigan H, Carp RI, Whitaker JN, Race R, Frey W, 2nd, Haase AT. Neuropathological changes in scrapie and alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J Virol 1991; 65:4759-4768
6. Duguid J, Trzepacz C. Major histocompatibility complex genes have an increased brain expression after scrapie infection. Proc Natl Acad Sci USA 1993; 90:114-117 (Pubitemid 23010260)
7. Diedrich JF, Carp RI, Haase AT. Increased expression of heat shock protein, transferrin and beta 2-microglobulin in astrocytes during scrapie. Microb Pathog 1993; 15:1-6. (Pubitemid 23273076)
8. Dandoy-Dron F, Guillo F, Benboudjema L, Deslys JP, Lasmezas C, Dormont D, et al. Gene expression in scrapie. cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J Biol Chem 1998; 273:7691-7697 (Pubitemid 28152798)
9. Baker CA, Manuelidis L. Unique inflammatory RNA profiles of microglia in creutzfeldtjakob disease. Proc Natl Acad Sci USA 2003; 100:675-679 (Pubitemid 36126111)
10. Booth S, Bowman C, Baumgartner R, Dolenko B, Sorensen G, Robertson C, et al. Molecular classification of scrapie strains in mice using gene expression profiling. Biochem Biophys Res Commun 2004; 325:1339-1345 (Pubitemid 39535910)
11. Booth S, Bowman C, Baumgartner R, Sorensen G, Robertson C, Coulthart M, et al. Identification of central nervous system genes involved in the host response to the scrapie agent during preclinical and clinical infection. J Gen Virol 2004; 85:3459-3471 (Pubitemid 39445467)
12. Brown AR, Webb J, Rebus S, Williams A, Fazakerley JK. Identification of upregulated genes by array analysis in scrapie-infected mouse brains. Neuropathol Appl Neurobiol 2004; 30:555-567 (Pubitemid 39423043)
13. Riemer C, Neidhold S, Burwinkel M, Schwarz A, Schultz J, Kratzschmar J, et al. Gene expression profiling of scrapie-infected brain tissue. Biochem Biophys Res Commun 2004; 323:556-564 (Pubitemid 39221133)
14. Xiang W, Windl O, Wunsch G, Dugas M, Kohlmann A, Dierkes N, et al. Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology. J Virol 2004; 78:11051-11060 (Pubitemid 39299645)
15. Brown AR, Rebus S, McKimmie CS, Robertson K, Williams A, Fazakerley JK. Gene expression profiling of the preclinical scrapie-infected hippocampus. Biochem Biophys Res Commun 2005; 334:86-95. (Pubitemid 40978510)
16. Skinner PJ, Abbassi H, Chesebro B, Race RE, Reilly C, Haase AT. Gene expression alterations in brains of mice infected with three strains of scrapie. BMC Genomics 2006; 7:114. (Pubitemid 43881125)
17. Xiang W, Hummel M, Mitteregger G, Pace C, Windl O, Mansmann U, Kretzschmar HA. Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model. J Neurochem 2007; 102:834-847 (Pubitemid 47057283)
18. Williams AE, Lawson LJ, Perry VH, Fraser H. Characterization of the microglial response in murine scrapie. Neuropathol Appl Neurobiol 1994; 20:47-55. (Pubitemid 24078165)
19. DeArmond SJ, Kristensson K, Bowler RP. PrPSc causes nerve cell death and stimulates astrocyte proliferation: A paradox. Prog Brain Res 1992; 94:437-446 (Pubitemid 23026668)
20. Eikelenboom P, Bate C, Van Gool WA, Hoozemans JJ, Rozemuller JM, Veerhuis R, Williams A. Neuroinflammation in alzheimer's disease and prion disease. Glia 2002; 40:232-239 (Pubitemid 35337380)
21. McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLADR in the substantia nigra of parkinson's and alzheimer's disease brains. Neurology 1988; 38:1285-1291 (Pubitemid 18218619)
22. Martino G, Adorini L, Rieckmann P, Hillert J, Kallmann B, Comi G, Filippi M. Inflammation in multiple sclerosis: The good, the bad and the complex. Lancet Neurol 2002; 1:499-509. (Pubitemid 37159141)
23. Greenwood AD, Horsch M, Stengel A, Vorberg I, Lutzny G, Maas E, et al. Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells. J Mol Biol 2005; 349:487-500. (Pubitemid 40724560)
24. Blakemore WF. Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice. J Neurocytol 1972; 1:413-426
25. Ludwin SK. Central nervous system demyelination and remyelination in the mouse: An ultrastructural study of cuprizone toxicity. Lab Invest 1978; 39:597-612. (Pubitemid 9080664)
26. Pattison IH, Jebbett JN. Histopathological similarities between scrapie and cuprizone toxicity in mice. Nature 1971; 230:115-117
27. Hiremath MM, Saito Y, Knapp GW, Ting JP, Suzuki K, Matsushima GK. Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice. J Neuroimmunol 1998; 92:38-49. (Pubitemid 29015988)
28. Bakker DA, Ludwin SK. Blood-brain barrier permeability during cuprizone-induced demyelination. implications for the pathogenesis of immune-mediated demyelinating diseases. J Neurol Sci 1987; 78:125-137 (Pubitemid 17031707)
29. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP. Exploration, normalization and summaries of high density oligonucleotide array probe level data. Biostatistics 2003; 4:249-264
30. Dennis G Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, Lempicki RA. DAVID: Database for annotation, visualization and integrated discovery. Genome Biol 2003; 4:3.
31. Hoefert VB, Aiken JM, McKenzie D, Johnson CJ. Labeling of the scrapie-associated prion protein in vitro and in vivo. Neurosci Lett 2004; 371:176-180 (Pubitemid 39440766)
32. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29:45.
33. Lee CK, Weindruch R, Prolla TA. Gene-expression profile of the ageing brain in mice. Nat Genet 2000; 25:294-297 (Pubitemid 30437315)
34. Lewicki H, Tishon A, Homann D, Mazarguil H, Laval F, Asensio VC, et al. T cells infiltrate the brain in murine and human transmissible spongiform encephalopathies. J Virol 2003; 77:3799-3808 (Pubitemid 36297298)
35. Porter DD, Porter HG, Cox NA. Failure to demonstrate a humoral immune response to scrapie infection in mice. J Immunol 1973; 111:1407-1410
36. Roberts ES, Zandonatti MA, Watry DD, Madden LJ, Henriksen SJ, Taffe MA, Fox HS. Induction of pathogenic sets of genes in macrophages and neurons in NeuroAIDS. Am J Pathol 2003; 162:2041-2057 (Pubitemid 36613060)
37. Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW. A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid. J Biol Chem 2002; 277:47373-47379 (Pubitemid 36163374)
38. Morell P, Barrett CV, Mason JL, Toews AD, Hostettler JD, Knapp GW, Matsushima GK. Gene expression in brain during cuprizone-induced demyelination and remyelination. Mol Cell Neurosci 1998; 12:220-227 (Pubitemid 28536075)
39. Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP. Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. J Neurosci 2003; 23:9824-9832 (Pubitemid 37371596)
40. Jurevics H, Largent C, Hostettler J, Sammond DW, Matsushima GK, Kleindienst A, et al. Alterations in metabolism and gene expression in brain regions during cuprizoneinduced demyelination and remyelination. J Neurochem 2002; 82:126-136 (Pubitemid 34755257)
41. Bedard A, Tremblay P, Chernomoretz A, Vallieres L. Identification of genes preferentially expressed by microglia and upregulated during cuprizone-induced inflammation. Glia 2007; 55:777-789 (Pubitemid 46787189)
42. Lopez I, Mak EC, Ding J, Hamm HE, Lomasney JW. A novel bifunctional phospholipase c that is regulated by galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway. J Biol Chem 2001; 276:2758-2765 (Pubitemid 37376654)
43. Shutter JR, Graham M, Kinsey AC, Scully S, Luthy R, Stark KL. Hypothalamic expression of ART, a novel gene related to agouti, is upregulated in obese and diabetic mutant mice. Genes Dev 1997; 11:593-602. (Pubitemid 27133379)
44. Ollmann MM, Wilson BD, Yang YK, Kerns JA, Chen Y, Gantz I, Barsh GS. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 1997; 278:135-138 (Pubitemid 27446294)
45. Guzik TJ, Mangalat D, Korbut R. Adipocytokines-novel link between inflammation and vascular function? J Physiol Pharmacol 2006; 57:505-528
46. Watson RT, Khan AH, Furukawa M, Hou JC, Li L, Kanzaki M, et al. Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent. EMBO J 2004; 23:2059-2070 (Pubitemid 38737733)
47. Emanuelli B, Peraldi P, Filloux C, Sawka-Verhelle D, Hilton D, Van Obberghen E. SOCS-3 is an insulin-induced negative regulator of insulin signaling. J Biol Chem 2000; 275:15985-15991 (Pubitemid 30366903)