메뉴 건너뛰기




Volumn 13, Issue 18, 2007, Pages 5271-5279

The B7 family and cancer therapy: Costimulation and coinhibition

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD86 ANTIGEN; CP 675206; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GLYCOPROTEIN GP 100; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; INTERLEUKIN 2; IPILIMUMAB; MAMMALIAN TARGET OF RAPAMYCIN; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN PD L1; T LYMPHOCYTE RECEPTOR; TUMOR CELL VACCINE; UNCLASSIFIED DRUG;

EID: 34848831575     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-1030     Document Type: Review
Times cited : (300)

References (97)
  • 1
    • 0023143676 scopus 로고
    • Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
    • Jenkins MK, Schwartz RH. Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J Exp Med 1987;165:302-19.
    • (1987) J Exp Med , vol.165 , pp. 302-319
    • Jenkins, M.K.1    Schwartz, R.H.2
  • 2
    • 0023514599 scopus 로고
    • Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system
    • Aruffo A, Seed B. Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc Natl Acad Sci U S A 1987;84:8573-7.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 8573-8577
    • Aruffo, A.1    Seed, B.2
  • 3
    • 0023270567 scopus 로고
    • A new member of the immunoglobulin superfamil - ECTLA-4
    • Brunet JF, Denizot F, Luciani MF, et al. A new member of the immunoglobulin superfamil - ECTLA-4. Nature 1987;328:267-70.
    • (1987) Nature , vol.328 , pp. 267-270
    • Brunet, J.F.1    Denizot, F.2    Luciani, M.F.3
  • 4
    • 0024444165 scopus 로고
    • B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells
    • Freeman GJ, Freedman AS, Segil JM, Lee G, Whitman JF, Nadler LM. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J Immunol 1989;143:2714-22.
    • (1989) J Immunol , vol.143 , pp. 2714-2722
    • Freeman, G.J.1    Freedman, A.S.2    Segil, J.M.3    Lee, G.4    Whitman, J.F.5    Nadler, L.M.6
  • 5
    • 0025322552 scopus 로고
    • T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1
    • Linsley PS, Clark EA, Ledbetter JA. T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Proc Natl Acad Sci U S A 1990;87:5031-5.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5031-5035
    • Linsley, P.S.1    Clark, E.A.2    Ledbetter, J.A.3
  • 7
    • 0025963594 scopus 로고
    • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
    • Linsley PS, Brady W, Grosmaire L, Aruffo A, Damle NK, Ledbetter JA. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J Exp Med 1991;173:721-30.
    • (1991) J Exp Med , vol.173 , pp. 721-730
    • Linsley, P.S.1    Brady, W.2    Grosmaire, L.3    Aruffo, A.4    Damle, N.K.5    Ledbetter, J.A.6
  • 8
    • 0025947446 scopus 로고
    • B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2
    • Gimmi CD, Freeman GJ, Gribben JG, et al. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc Natl Acad Sci U S A 1991;88:6575-9.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 6575-6579
    • Gimmi, C.D.1    Freeman, G.J.2    Gribben, J.G.3
  • 9
    • 0025971681 scopus 로고
    • The CD28 ligand B7/BB1provides costimulatory signal for alloactivation of CD4+ T cells
    • Koulova L, Clark EA, Shu G, Dupont B. The CD28 ligand B7/BB1provides costimulatory signal for alloactivation of CD4+ T cells. J Exp Med 1991;173:759-62.
    • (1991) J Exp Med , vol.173 , pp. 759-762
    • Koulova, L.1    Clark, E.A.2    Shu, G.3    Dupont, B.4
  • 10
    • 0026537347 scopus 로고
    • CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP. CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 1992;356:607-9.
    • (1992) Nature , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 11
    • 0027767762 scopus 로고
    • Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation
    • Freeman GJ, Gribben JG, Boussiotis VA, et al. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 1993;262:909-11.
    • (1993) Science , vol.262 , pp. 909-911
    • Freeman, G.J.1    Gribben, J.G.2    Boussiotis, V.A.3
  • 12
    • 0027362823 scopus 로고
    • B70 antigen is a second ligand for CTLA-4 and CD28
    • Azuma M, Ito D, Yagita H, et al. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 1993;366:76-9.
    • (1993) Nature , vol.366 , pp. 76-79
    • Azuma, M.1    Ito, D.2    Yagita, H.3
  • 13
    • 0033212778 scopus 로고    scopus 로고
    • B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFα
    • Swallow MM, Wallin JJ, Sha WC. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFα. Immunity 1999;11:423-32.
    • (1999) Immunity , vol.11 , pp. 423-432
    • Swallow, M.M.1    Wallin, J.J.2    Sha, W.C.3
  • 14
    • 0032736029 scopus 로고    scopus 로고
    • B7-1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
    • Dong H, Zhu G, Tamada K, Chen L. B7-1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med 1999;5:1365-9.
    • (1999) Nat Med , vol.5 , pp. 1365-1369
    • Dong, H.1    Zhu, G.2    Tamada, K.3    Chen, L.4
  • 15
    • 0033590502 scopus 로고    scopus 로고
    • ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
    • Hutloff A, Dittrich AM, Beier KC, et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999;397:263-6.
    • (1999) Nature , vol.397 , pp. 263-266
    • Hutloff, A.1    Dittrich, A.M.2    Beier, K.C.3
  • 16
    • 0033576707 scopus 로고    scopus 로고
    • T-cell co-stimulation through B7RP-1 and ICOS
    • Yoshinaga SK, Whoriskey JS, Khare SD, et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature 1999;402:827-32.
    • (1999) Nature , vol.402 , pp. 827-832
    • Yoshinaga, S.K.1    Whoriskey, J.S.2    Khare, S.D.3
  • 17
    • 0034651694 scopus 로고    scopus 로고
    • Cutting edge: Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor
    • Ling V, Wu PW, Finnerty HF, et al. Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor. J Immunol 2000;164:1653-7.
    • (2000) J Immunol , vol.164 , pp. 1653-1657
    • Ling, V.1    Wu, P.W.2    Finnerty, H.F.3
  • 18
    • 0034667688 scopus 로고    scopus 로고
    • Costimulation of T cells by B7-2, a B7-like molecule that binds ICOS
    • Wang S, Zhu G, Chapoval AI, et al. Costimulation of T cells by B7-2, a B7-like molecule that binds ICOS. Blood 2000;96:2808-13.
    • (2000) Blood , vol.96 , pp. 2808-2813
    • Wang, S.1    Zhu, G.2    Chapoval, A.I.3
  • 19
    • 0034704760 scopus 로고    scopus 로고
    • LICOS, a primordial costimulatory ligand?
    • Brodie D, Collins AV, Iaboni A, et al. LICOS, a primordial costimulatory ligand? Curr Biol 2000;10:333-6.
    • (2000) Curr Biol , vol.10 , pp. 333-336
    • Brodie, D.1    Collins, A.V.2    Iaboni, A.3
  • 20
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • Freeman GJ, Long AJ, Iwai Y, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000;192:1027-34.
    • (2000) J Exp Med , vol.192 , pp. 1027-1034
    • Freeman, G.J.1    Long, A.J.2    Iwai, Y.3
  • 21
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992;11:3887-95.
    • (1992) EMBO J , vol.11 , pp. 3887-3895
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3    Honjo, T.4
  • 22
    • 5844264920 scopus 로고    scopus 로고
    • PD-L2 is a second ligand for PD-1 and inhibits T cell activation
    • Latchman Y, Wood CR, Chernova T, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001;2:261-8.
    • (2001) Nat Immunol , vol.2 , pp. 261-268
    • Latchman, Y.1    Wood, C.R.2    Chernova, T.3
  • 23
    • 0035794314 scopus 로고    scopus 로고
    • B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
    • Tseng SY, Otsuji M, Gorski K, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med 2001;193:839-46.
    • (2001) J Exp Med , vol.193 , pp. 839-846
    • Tseng, S.Y.1    Otsuji, M.2    Gorski, K.3
  • 24
    • 5844252552 scopus 로고    scopus 로고
    • B7-H3: A costimulatory molecule for T cell activation and IFN-γ production
    • Chapoval AI, Ni J, Lau JS, et al. B7-H3: a costimulatory molecule for T cell activation and IFN-γ production. Nat Immunol 2001;2:269-74.
    • (2001) Nat Immunol , vol.2 , pp. 269-274
    • Chapoval, A.I.1    Ni, J.2    Lau, J.S.3
  • 25
    • 0042337394 scopus 로고    scopus 로고
    • Zang X, Loke P, Kim J, Murphy K, Waitz R, Allison JP. B7x: a widely expressed B7 family member that inhibits T cell activation. Proc Natl Acad Sci U S A 2003;100:10388-92.
    • Zang X, Loke P, Kim J, Murphy K, Waitz R, Allison JP. B7x: a widely expressed B7 family member that inhibits T cell activation. Proc Natl Acad Sci U S A 2003;100:10388-92.
  • 26
    • 0038094524 scopus 로고    scopus 로고
    • B7-H4, a molecule of the B7 family, negatively regulates T cell immunity
    • Sica GL, Choi IH, Zhu G, et al. B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. Immunity 2003;18:849-61.
    • (2003) Immunity , vol.18 , pp. 849-861
    • Sica, G.L.1    Choi, I.H.2    Zhu, G.3
  • 27
    • 0038433329 scopus 로고    scopus 로고
    • B7S1, a novel B7 family member that negatively regulates T cell activation
    • Prasad DV, Richards S, Mai XM, Dong C. B7S1, a novel B7 family member that negatively regulates T cell activation. Immunity 2003;18:863-73.
    • (2003) Immunity , vol.18 , pp. 863-873
    • Prasad, D.V.1    Richards, S.2    Mai, X.M.3    Dong, C.4
  • 28
    • 33749443579 scopus 로고    scopus 로고
    • To be or not to be B7
    • Zang X, Allison JP. To be or not to be B7. J Clin Invest 2006;116:2590-3.
    • (2006) J Clin Invest , vol.116 , pp. 2590-2593
    • Zang, X.1    Allison, J.P.2
  • 29
    • 0027281691 scopus 로고
    • Differential T cell costimulatory requirements in CD28-deficient mice
    • Shahinian A, Pfeffer K, Lee KP, et al. Differential T cell costimulatory requirements in CD28-deficient mice. Science 1993;261:609-12.
    • (1993) Science , vol.261 , pp. 609-612
    • Shahinian, A.1    Pfeffer, K.2    Lee, K.P.3
  • 30
    • 0028791059 scopus 로고
    • Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
    • Waterhouse P, Penninger JM, Timms E, et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995;270:985-8.
    • (1995) Science , vol.270 , pp. 985-988
    • Waterhouse, P.1    Penninger, J.M.2    Timms, E.3
  • 31
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995;3:541-7.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 32
    • 0031405867 scopus 로고    scopus 로고
    • Chambers CA, Sullivan TJ, Allison JP. Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells. Immunity 1997;7:885-95.
    • Chambers CA, Sullivan TJ, Allison JP. Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells. Immunity 1997;7:885-95.
  • 33
    • 0035804268 scopus 로고    scopus 로고
    • IC OS is critical for CD40-mediated antibody class switching
    • McAdam AJ, Greenwald RJ, Levin MA, et al. IC OS is critical for CD40-mediated antibody class switching. Nature 2001;409:102-5.
    • (2001) Nature , vol.409 , pp. 102-105
    • McAdam, A.J.1    Greenwald, R.J.2    Levin, M.A.3
  • 34
    • 0035804254 scopus 로고    scopus 로고
    • ICOS costimulatory receptor is essential for T-cell activation and function
    • Dong C, Juedes AE, Temann UA, et al. ICOS costimulatory receptor is essential for T-cell activation and function. Nature 2001;409:97-101.
    • (2001) Nature , vol.409 , pp. 97-101
    • Dong, C.1    Juedes, A.E.2    Temann, U.A.3
  • 35
    • 0035804269 scopus 로고    scopus 로고
    • ICOS is essential for effective T-helper-cell responses
    • Tafuri A, Shahinian A, Bladt F, et al. ICOS is essential for effective T-helper-cell responses. Nature 2001;409:105-9.
    • (2001) Nature , vol.409 , pp. 105-109
    • Tafuri, A.1    Shahinian, A.2    Bladt, F.3
  • 36
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • Barber DL, Wherry EJ, Masopust D, et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006;439:682-7.
    • (2006) Nature , vol.439 , pp. 682-687
    • Barber, D.L.1    Wherry, E.J.2    Masopust, D.3
  • 37
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999;11:141-51.
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 38
    • 0035846991 scopus 로고    scopus 로고
    • Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
    • Nishimura H, Okazaki T, Tanaka Y, et al. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 2001;291:319-22.
    • (2001) Science , vol.291 , pp. 319-322
    • Nishimura, H.1    Okazaki, T.2    Tanaka, Y.3
  • 39
    • 33645846313 scopus 로고    scopus 로고
    • Tissue expression of PD-L1mediates peripheral T cell tolerance
    • Keir ME, Liang SC, Guleria I, et al. Tissue expression of PD-L1mediates peripheral T cell tolerance. J Exp Med 2006;203:883-95.
    • (2006) J Exp Med , vol.203 , pp. 883-895
    • Keir, M.E.1    Liang, S.C.2    Guleria, I.3
  • 40
    • 0043123303 scopus 로고    scopus 로고
    • Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: Divergent history of functional redundancy and exonloss
    • Ling V, Wu PW, Spaulding V, et al. Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exonloss. Genomics 2003;82:365-77.
    • (2003) Genomics , vol.82 , pp. 365-377
    • Ling, V.1    Wu, P.W.2    Spaulding, V.3
  • 41
    • 4043099691 scopus 로고    scopus 로고
    • Murine B7-H3 is a negative regulator of T cells
    • Prasad DV, Nguyen T, Li Z, et al. Murine B7-H3 is a negative regulator of T cells. J Immunol 2004;173:2500-6.
    • (2004) J Immunol , vol.173 , pp. 2500-2506
    • Prasad, D.V.1    Nguyen, T.2    Li, Z.3
  • 42
    • 0041381300 scopus 로고    scopus 로고
    • The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses
    • Suh WK, Gajewska BU, Okada H, et al. The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses. Nat Immunol 2003;4:899-906.
    • (2003) Nat Immunol , vol.4 , pp. 899-906
    • Suh, W.K.1    Gajewska, B.U.2    Okada, H.3
  • 43
    • 0027392843 scopus 로고
    • Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells
    • Townsend SE, Allison JP. Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells. Science 1993;259:368-70.
    • (1993) Science , vol.259 , pp. 368-370
    • Townsend, S.E.1    Allison, J.P.2
  • 44
    • 0027078670 scopus 로고
    • Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
    • Chen L, Ashe S, Brady WA, et al. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 1992;71:1093-102.
    • (1992) Cell , vol.71 , pp. 1093-1102
    • Chen, L.1    Ashe, S.2    Brady, W.A.3
  • 45
    • 0027211058 scopus 로고
    • Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules
    • Baskar S, Ostrand-Rosenberg S, Nabavi N, Nadler LM, Freeman GJ, Glimcher LH. Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules. Proc Natl Acad Sci U S A 1993;90:5687-90.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5687-5690
    • Baskar, S.1    Ostrand-Rosenberg, S.2    Nabavi, N.3    Nadler, L.M.4    Freeman, G.J.5    Glimcher, L.H.6
  • 46
    • 0028036728 scopus 로고
    • Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1or B7-2 costimulatory molecules
    • Hodge JW, Abrams S, Schlom J, Kantor JA. Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1or B7-2 costimulatory molecules. Cancer Res 1994;54:5552-5.
    • (1994) Cancer Res , vol.54 , pp. 5552-5555
    • Hodge, J.W.1    Abrams, S.2    Schlom, J.3    Kantor, J.A.4
  • 47
    • 0035399581 scopus 로고    scopus 로고
    • Enhancement of CD8+ T cell responses by ICOS/B7h costimulation
    • Wallin JJ, Liang L, Bakardjiev A, Sha WC. Enhancement of CD8+ T cell responses by ICOS/B7h costimulation. JImmunol 2001;167:132-9.
    • (2001) JImmunol , vol.167 , pp. 132-139
    • Wallin, J.J.1    Liang, L.2    Bakardjiev, A.3    Sha, W.C.4
  • 49
    • 0027982995 scopus 로고
    • Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity
    • Chen L, McGowan P, Ashe S, et al. Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity. J Exp Med 1994;179:523-32.
    • (1994) J Exp Med , vol.179 , pp. 523-532
    • Chen, L.1    McGowan, P.2    Ashe, S.3
  • 50
    • 0036223749 scopus 로고    scopus 로고
    • Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma
    • Antonia SJ, Seigne J, Diaz J, et al. Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma. J Urol 2002;167:1995-2000.
    • (2002) J Urol , vol.167 , pp. 1995-2000
    • Antonia, S.J.1    Seigne, J.2    Diaz, J.3
  • 51
    • 4344559720 scopus 로고    scopus 로고
    • Allogeneic vaccination with a B7.1 HLA-A gene-modified adenocarcinoma cell line in patients with advanced non-small-cell lung cancer
    • Raez LE, Cassileth PA, Schlesselman JJ, et al. Allogeneic vaccination with a B7.1 HLA-A gene-modified adenocarcinoma cell line in patients with advanced non-small-cell lung cancer. J Clin Oncol 2004;22:2800-7.
    • (2004) J Clin Oncol , vol.22 , pp. 2800-2807
    • Raez, L.E.1    Cassileth, P.A.2    Schlesselman, J.J.3
  • 52
    • 33646347162 scopus 로고    scopus 로고
    • An immune edited tumour versus a tumour edited immune system: Prospects for immune therapy of acute myeloid leukaemia
    • Chan L, Hardwick NR, Guinn BA, et al. An immune edited tumour versus a tumour edited immune system: prospects for immune therapy of acute myeloid leukaemia. C ancer Immunol Immunother 2006;55:1017-24.
    • (2006) C ancer Immunol Immunother , vol.55 , pp. 1017-1024
    • Chan, L.1    Hardwick, N.R.2    Guinn, B.A.3
  • 53
    • 33644520242 scopus 로고    scopus 로고
    • Lowsurface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma
    • Tirapu I, Huarte E, Guiducci C, et al. Lowsurface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma. Cancer Res 2006;66:2442-50.
    • (2006) Cancer Res , vol.66 , pp. 2442-2450
    • Tirapu, I.1    Huarte, E.2    Guiducci, C.3
  • 54
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang AY, Golumbek P, Ahmadzadeh M, Jaffee E, Pardoll D, Levitsky H. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science 1994;264:961-5.
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.Y.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 55
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996;271:1734-6.
    • (1996) Science , vol.271 , pp. 1734-1736
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 56
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen JG, Kuhns MS, Allison JP. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat Immunol 2002;3:611- 8.
    • (2002) Nat Immunol , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 57
    • 0344341626 scopus 로고    scopus 로고
    • Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
    • Hodi FS, Mihm MC, Soiffer RJ, et al. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci U S A 2003;100:4712-7.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4712-4717
    • Hodi, F.S.1    Mihm, M.C.2    Soiffer, R.J.3
  • 58
    • 34250223096 scopus 로고    scopus 로고
    • A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer
    • Small EJ, Tchekmedyian NS, Rini BI, Fong L, Lowy I, Allison JP. A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer. Clin Cancer Res 2007;13:1810-5.
    • (2007) Clin Cancer Res , vol.13 , pp. 1810-1815
    • Small, E.J.1    Tchekmedyian, N.S.2    Rini, B.I.3    Fong, L.4    Lowy, I.5    Allison, J.P.6
  • 59
    • 32644467549 scopus 로고    scopus 로고
    • Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
    • Ribas A, Camacho LH, Lopez-Berestein G, et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol 2005;23:8968-77.
    • (2005) J Clin Oncol , vol.23 , pp. 8968-8977
    • Ribas, A.1    Camacho, L.H.2    Lopez-Berestein, G.3
  • 60
    • 24944459890 scopus 로고    scopus 로고
    • Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
    • Attia P, Phan GQ, Maker AV, et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 2005;23:6043-53.
    • (2005) J Clin Oncol , vol.23 , pp. 6043-6053
    • Attia, P.1    Phan, G.Q.2    Maker, A.V.3
  • 61
    • 0038153907 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
    • Phan GQ, Yang JC, Sherry RM, et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A 2003;100:8372-7.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8372-8377
    • Phan, G.Q.1    Yang, J.C.2    Sherry, R.M.3
  • 62
    • 20044395957 scopus 로고    scopus 로고
    • Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and montanide ISA 51 for patients with resected stages III and IV melanoma
    • Sanderson K, Scotland R, Lee P, et al. Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and montanide ISA 51 for patients with resected stages III and IV melanoma. J Clin Oncol 2005;23:741-50.
    • (2005) J Clin Oncol , vol.23 , pp. 741-750
    • Sanderson, K.1    Scotland, R.2    Lee, P.3
  • 63
    • 33847407907 scopus 로고    scopus 로고
    • A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy
    • O'Mahony D, Morris JC, Quinn C, et al. A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy. Clin Cancer Res 2007;13:958-64.
    • (2007) Clin Cancer Res , vol.13 , pp. 958-964
    • O'Mahony, D.1    Morris, J.C.2    Quinn, C.3
  • 64
    • 33744792341 scopus 로고    scopus 로고
    • Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
    • Beck KE, Blansfield JA, Tran KQ, et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol 2006;24:2283-9.
    • (2006) J Clin Oncol , vol.24 , pp. 2283-2289
    • Beck, K.E.1    Blansfield, J.A.2    Tran, K.Q.3
  • 65
    • 27844458057 scopus 로고    scopus 로고
    • Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: A phase I/II study
    • Maker AV, Phan GQ, Attia P, et al. Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study. Ann Surg Oncol 2005;12:1005-16.
    • (2005) Ann Surg Oncol , vol.12 , pp. 1005-1016
    • Maker, A.V.1    Phan, G.Q.2    Attia, P.3
  • 71
    • 20744432041 scopus 로고    scopus 로고
    • Tumor immunotherapy: Preclinical and clinical activity of anti-CTLA4 antibodies
    • Korman A, Yellin M, Keler T. Tumor immunotherapy: preclinical and clinical activity of anti-CTLA4 antibodies. Curr Opin Investig Drugs 2005;6:582-91.
    • (2005) Curr Opin Investig Drugs , vol.6 , pp. 582-591
    • Korman, A.1    Yellin, M.2    Keler, T.3
  • 72
    • 28244492012 scopus 로고    scopus 로고
    • Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
    • Maker AV, Attia P, Rosenberg SA. Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade. J Immunol 2005;175:7746-54.
    • (2005) J Immunol , vol.175 , pp. 7746-7754
    • Maker, A.V.1    Attia, P.2    Rosenberg, S.A.3
  • 73
    • 33745851479 scopus 로고    scopus 로고
    • CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
    • Quezada SA, Peggs KS, Curran MA, Allison JP. CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells. J Clin Invest 2006;116:1935-45.
    • (2006) J Clin Invest , vol.116 , pp. 1935-1945
    • Quezada, S.A.1    Peggs, K.S.2    Curran, M.A.3    Allison, J.P.4
  • 74
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • van Elsas A, Hurwitz AA, Allison JP. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 1999;190:355-66.
    • (1999) J Exp Med , vol.190 , pp. 355-366
    • van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 75
    • 0035903324 scopus 로고    scopus 로고
    • + regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • + regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 2001;194:823-32.
    • (2001) J Exp Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3
  • 76
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E, Lazenby A, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A 1993;90:3539-43.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3
  • 77
    • 33846852187 scopus 로고    scopus 로고
    • Implications of B7-1expression in clear cell carcinoma of the kidney for prognostication and therapy
    • s
    • Thompson RH, Dong H, Kwon ED. Implications of B7-1expression in clear cell carcinoma of the kidney for prognostication and therapy. Clin Cancer Res 2007;13:709-15s.
    • (2007) Clin Cancer Res , vol.13 , pp. 709-715
    • Thompson, R.H.1    Dong, H.2    Kwon, E.D.3
  • 78
    • 10344220548 scopus 로고    scopus 로고
    • Costimulatory B7-1in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target
    • Thompson RH, Gillett MD, Cheville JC, et al. Costimulatory B7-1in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target. Proc Natl Acad Sci U S A 2004;101:17174-9.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17174-17179
    • Thompson, R.H.1    Gillett, M.D.2    Cheville, J.C.3
  • 79
    • 4243096258 scopus 로고    scopus 로고
    • B7-1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression
    • Konishi J, Yamazaki K, Azuma M, Kinoshita I, Dosaka-Akita H, Nishimura M. B7-1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression. Clin Cancer Res 2004;10:5094-100.
    • (2004) Clin Cancer Res , vol.10 , pp. 5094-5100
    • Konishi, J.1    Yamazaki, K.2    Azuma, M.3    Kinoshita, I.4    Dosaka-Akita, H.5    Nishimura, M.6
  • 80
    • 33646367200 scopus 로고    scopus 로고
    • The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: Correlation with important high-risk prognostic factors
    • Ghebeh H, Mohammed S, Al-Omair A, et al. The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors. Neoplasia 2006;8:190-8.
    • (2006) Neoplasia , vol.8 , pp. 190-198
    • Ghebeh, H.1    Mohammed, S.2    Al-Omair, A.3
  • 81
    • 33847611968 scopus 로고    scopus 로고
    • Programmed cell death1 ligand1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
    • Hamanishi J, Mandai M, Iwasaki M, et al. Programmed cell death1 ligand1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer. Proc Natl Acad Sci U S A 2007;104:3360-5.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3360-3365
    • Hamanishi, J.1    Mandai, M.2    Iwasaki, M.3
  • 82
    • 33745491116 scopus 로고    scopus 로고
    • Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance
    • Wu C , Zhu Y, Jiang J, Zhao J, Zhang XG, Xu N. Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance. Acta Histochem 2006;108:19-24.
    • (2006) Acta Histochem , vol.108 , pp. 19-24
    • Wu, C.1    Zhu, Y.2    Jiang, J.3    Zhao, J.4    Zhang, X.G.5    Xu, N.6
  • 83
    • 34247113727 scopus 로고    scopus 로고
    • PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: Associations with localized stage progression
    • Inman BA, Sebo TJ, Frigola X, et al. PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression. Cancer 2007;109:1499-505.
    • (2007) Cancer , vol.109 , pp. 1499-1505
    • Inman, B.A.1    Sebo, T.J.2    Frigola, X.3
  • 84
    • 34248586083 scopus 로고    scopus 로고
    • Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and post-operative prognosis in human urothelial cancers
    • Nakanishi J, Wada Y, Matsumoto K, Azuma M, Kikuchi K, Ueda S. Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and post-operative prognosis in human urothelial cancers. Cancer Immunol Immunother 2007;56:1173-82.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1173-1182
    • Nakanishi, J.1    Wada, Y.2    Matsumoto, K.3    Azuma, M.4    Kikuchi, K.5    Ueda, S.6
  • 85
    • 34247532726 scopus 로고    scopus 로고
    • Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer
    • Nomi T, Sho M, Akahori T, et al. Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer. Clin Cancer Res 2007;13:2151-7.
    • (2007) Clin Cancer Res , vol.13 , pp. 2151-2157
    • Nomi, T.1    Sho, M.2    Akahori, T.3
  • 86
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002;8:793-800.
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3
  • 87
    • 33846118474 scopus 로고    scopus 로고
    • Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
    • Parsa AT, Waldron JS, Panner A, et al. Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med 2007;13:84-8.
    • (2007) Nat Med , vol.13 , pp. 84-88
    • Parsa, A.T.1    Waldron, J.S.2    Panner, A.3
  • 88
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1blockade
    • Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1blockade. Proc Natl Acad Sci U S A 2002;99:12293-7.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 89
    • 0141953992 scopus 로고    scopus 로고
    • B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma
    • Strome SE, Dong H, Tamura H, et al. B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma. Cancer Res 2003;63:6501-5.
    • (2003) Cancer Res , vol.63 , pp. 6501-6505
    • Strome, S.E.1    Dong, H.2    Tamura, H.3
  • 90
    • 13444270323 scopus 로고    scopus 로고
    • Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
    • Hirano F, Kaneko K, Tamura H, et al. Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res 2005;65:1089-96.
    • (2005) Cancer Res , vol.65 , pp. 1089-1096
    • Hirano, F.1    Kaneko, K.2    Tamura, H.3
  • 91
    • 13844294372 scopus 로고    scopus 로고
    • PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells
    • Iwai Y, Terawaki S, Honjo T. PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. Int Immunol 2005;17:133-44.
    • (2005) Int Immunol , vol.17 , pp. 133-144
    • Iwai, Y.1    Terawaki, S.2    Honjo, T.3
  • 92
    • 0842325739 scopus 로고    scopus 로고
    • PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells
    • Blank C, Brown I, Peterson AC, et al. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res 2004;64:1140-5.
    • (2004) Cancer Res , vol.64 , pp. 1140-1145
    • Blank, C.1    Brown, I.2    Peterson, A.C.3
  • 93
    • 30044437872 scopus 로고    scopus 로고
    • Breaking down the barriers to cancer immunotherapy
    • Pure E, Allison JP, Schreiber RD. Breaking down the barriers to cancer immunotherapy. Nat Immunol 2005;6:1207-10.
    • (2005) Nat Immunol , vol.6 , pp. 1207-1210
    • Pure, E.1    Allison, J.P.2    Schreiber, R.D.3
  • 94
    • 33745605153 scopus 로고    scopus 로고
    • B7-H3 and B7-H4 expression in non-small-cell lung cancer
    • Sun Y, Wang Y, Zhao J, et al. B7-H3 and B7-H4 expression in non-small-cell lung cancer. Lung Cancer 2006;53:143-51.
    • (2006) Lung Cancer , vol.53 , pp. 143-151
    • Sun, Y.1    Wang, Y.2    Zhao, J.3
  • 95
    • 18844373949 scopus 로고    scopus 로고
    • The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation
    • Salceda S, Tang T, Kmet M, et al. The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation. Exp Cell Res 2005;306:128-41.
    • (2005) Exp Cell Res , vol.306 , pp. 128-141
    • Salceda, S.1    Tang, T.2    Kmet, M.3
  • 96
    • 16344391363 scopus 로고    scopus 로고
    • B7-H4 is highly expressed in ductal and lobular breast cancer
    • Tringler B, Zhuo S, Pilkington G, et al. B7-H4 is highly expressed in ductal and lobular breast cancer. Clin Cancer Res 2005;11:1842-8.
    • (2005) Clin Cancer Res , vol.11 , pp. 1842-1848
    • Tringler, B.1    Zhuo, S.2    Pilkington, G.3
  • 97
    • 33745886516 scopus 로고    scopus 로고
    • B7-H4 expression in renal cell carcinoma and tumor vasculature: Associations with cancer progression and survival
    • Krambeck AE, Thompson RH, Dong H, et al. B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival. Proc Natl Acad Sci U S A 2006;103:10391-6.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 10391-10396
    • Krambeck, A.E.1    Thompson, R.H.2    Dong, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.