-
1
-
-
77952424081
-
Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection
-
Faurez F, Dory D, Le Moigne V, et al. Biosafety of DNA vaccines: new generation of DNA vectors and current knowledge on the fate of plasmids after injection. Vaccine. 2010;28: 3888-3895.
-
(2010)
Vaccine
, vol.28
, pp. 3888-3895
-
-
Faurez, F.1
Dory, D.2
Le Moigne, V.3
-
2
-
-
56149122138
-
Molecular and cellular mechanisms of DNA vaccines
-
Coban C, Koyama S, Takeshita F, et al. Molecular and cellular mechanisms of DNA vaccines. Hum Vaccin. 2008; 4:453-456.
-
(2008)
Hum Vaccin
, vol.4
, pp. 453-456
-
-
Coban, C.1
Koyama, S.2
Takeshita, F.3
-
3
-
-
33646568454
-
Gene-based vaccines: Recent technical and clinical advances
-
DOI 10.1016/j.molmed.2006.03.007, PII S1471491406000657
-
Ulmer JB, Wahren B, Liu MA. Gene-based vaccines: recent technical and clinical advances. Trends Mol Med. 2006;12: 216-222. (Pubitemid 43728411)
-
(2006)
Trends in Molecular Medicine
, vol.12
, Issue.5
, pp. 216-222
-
-
Ulmer, J.B.1
Wahren, B.2
Liu, M.A.3
-
4
-
-
0037111483
-
Expression of programmed death 1 ligands by murine T cells and APC
-
Yamazaki T, Akiba H, Iwai H, et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol. 2002;169:5538-5545. (Pubitemid 35291652)
-
(2002)
Journal of Immunology
, vol.169
, Issue.10
, pp. 5538-5545
-
-
Yamazaki, T.1
Akiba, H.2
Iwai, H.3
Matsuda, H.4
Aoki, M.5
Tanno, Y.6
Shin, T.7
Tsuchiya, H.8
Pardoll, D.M.9
Okumura, K.10
Azuma, M.11
Yagita, H.12
-
6
-
-
47049083508
-
Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques
-
Hokey DA, Johnson FB, Smith J, et al. Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques. Eur J Immunol. 2008;38: 1435-1445.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1435-1445
-
-
Hokey, D.A.1
Johnson, F.B.2
Smith, J.3
-
7
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
DOI 10.1038/ni1443, PII NI1443
-
Sharpe AH, Wherry EJ, Ahmed R, et al. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol. 2007;8:239-245. (Pubitemid 46745373)
-
(2007)
Nature Immunology
, vol.8
, Issue.3
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
8
-
-
34547794178
-
PD-1 and PD-1 ligands: From discovery to clinical application
-
DOI 10.1093/intimm/dxm057
-
Okazaki T, Honjo T. PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol. 2007;19:813-824. (Pubitemid 47241890)
-
(2007)
International Immunology
, vol.19
, Issue.7
, pp. 813-824
-
-
Okazaki, T.1
Honjo, T.2
-
10
-
-
33847401888
-
Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: An update on implications for chronic infections and tumor evasion
-
DOI 10.1007/s00262-006-0272-1
-
Blank C, Mackensen A. Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion. Cancer Immunol Immunother. 2007;56:739-745. (Pubitemid 46348742)
-
(2007)
Cancer Immunology, Immunotherapy
, vol.56
, Issue.5
, pp. 739-745
-
-
Blank, C.1
Mackensen, A.2
-
11
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
DOI 10.1016/j.immuni.2007.05.016, PII S1074761307003287
-
Butte MJ, Keir ME, Phamduy TB, et al. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity. 2007;27: 111-122. (Pubitemid 47089023)
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
12
-
-
22544479154
-
+ T cell effector functions after antigen recognition in the liver
-
DOI 10.1016/j.immuni.2005.05.005, PII S1074761305001986
-
Isogawa M, Furuichi Y, Chisari FV. Oscillating CD8(+) T cell effector functions after antigen recognition in the liver. Immunity. 2005;23:53-63. (Pubitemid 41019657)
-
(2005)
Immunity
, vol.23
, Issue.1
, pp. 53-63
-
-
Isogawa, M.1
Furuichi, Y.2
Chisari, F.V.3
-
13
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
Velu V, Titanji K, Zhu B, et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature. 2009;458:206-210.
-
(2009)
Nature
, vol.458
, pp. 206-210
-
-
Velu, V.1
Titanji, K.2
Zhu, B.3
-
14
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
DOI 10.1038/nature04444, PII NATURE04444
-
Barber DL, Wherry EJ, Masopust D, et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature. 2006;439:682-687. (Pubitemid 43237609)
-
(2006)
Nature
, vol.439
, Issue.7077
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
15
-
-
13444270323
-
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
-
Hirano F, Kaneko K, Tamura H, et al. Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res. 2005;65:1089-1096. (Pubitemid 40216472)
-
(2005)
Cancer Research
, vol.65
, Issue.3
, pp. 1089-1096
-
-
Hirano, F.1
Kaneko, K.2
Tamura, H.3
Dong, H.4
Wang, S.5
Ichikawa, M.6
Rietz, C.7
Flies, D.B.8
Lau, J.S.9
Zhu, G.10
Tamada, K.11
Chen, L.12
-
16
-
-
33646345848
-
HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma
-
DOI 10.1002/ijc.21795
-
Geng H, Zhang GM, Xiao H, et al. HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma. Int J Cancer. 2006;118:2657-2664. (Pubitemid 43673341)
-
(2006)
International Journal of Cancer
, vol.118
, Issue.11
, pp. 2657-2664
-
-
Geng, H.1
Zhang, G.-M.2
Xiao, H.3
Yuan, Y.4
Li, P.5
Zhang, H.6
Qiu, H.7
He, Y.-F.8
Feng, Z.-H.9
-
17
-
-
49649114804
-
Phase i safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R, Rotem-Yehudar R, Slama G, et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin Cancer Res. 2008;14:3044-3051.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
-
18
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28:3167-3175.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
19
-
-
75149194434
-
Marked enhancement of antigen-specific T-cell responses by IL-7-fused nonlytic, but not lytic, Fc as a genetic adjuvant
-
Nam HJ, Song MY, Choi DH, et al. Marked enhancement of antigen-specific T-cell responses by IL-7-fused nonlytic, but not lytic, Fc as a genetic adjuvant. Eur J Immunol. 2009;40: 351-358.
-
(2009)
Eur J Immunol
, vol.40
, pp. 351-358
-
-
Nam, H.J.1
Song, M.Y.2
Choi, D.H.3
-
20
-
-
0041375540
-
Therapeutic effect of DNA vaccines combined with chemotherapy in a latent infection model after aerosol infection of mice with Mycobacterium tuberculosis
-
Ha SJ, Jeon BY, Kim SC, et al. Therapeutic effect of DNA vaccines combined with chemotherapy in a latent infection model after aerosol infection of mice with Mycobacterium tuberculosis. Gene Ther. 2003;10:1592-1599.
-
(2003)
Gene Ther
, vol.10
, pp. 1592-1599
-
-
Ha, S.J.1
Jeon, B.Y.2
Kim, S.C.3
-
21
-
-
16344371747
-
Enhancement of interleukin-12 gene-based tumor immunotherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor
-
Jin HT, Youn JI, Kim HJ, et al. Enhancement of interleukin-12 gene-based tumor immunotherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor. Hum Gene Ther. 2005;16:328-338.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 328-338
-
-
Jin, H.T.1
Youn, J.I.2
Kim, H.J.3
-
22
-
-
0034652784
-
Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene
-
Chen CH, Wang TL, Hung CF, et al. Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene. Cancer Res. 2000;60:1035-1042.
-
(2000)
Cancer Res
, vol.60
, pp. 1035-1042
-
-
Chen, C.H.1
Wang, T.L.2
Hung, C.F.3
-
23
-
-
0142185336
-
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
-
DOI 10.1016/S0022-1759(03)00265-5
-
+ T cells by a flow cytometric assay for degranulation. J Immunol Methods. 2003;281:65-78. (Pubitemid 37324571)
-
(2003)
Journal of Immunological Methods
, vol.281
, Issue.1-2
, pp. 65-78
-
-
Betts, M.R.1
Brenchley, J.M.2
Price, D.A.3
De Rosa, S.C.4
Douek, D.C.5
Roederer, M.6
Koup, R.A.7
-
24
-
-
0033012030
-
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
-
DOI 10.1016/S0022-1759(98)00204-X, PII S002217599800204X
-
Lutz MB, Kukutsch N, Ogilvie AL, et al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods. 1999;223:77-92. (Pubitemid 29096240)
-
(1999)
Journal of Immunological Methods
, vol.223
, Issue.1
, pp. 77-92
-
-
Lutz, M.B.1
Kukutsch, N.2
Ogilvie, A.L.J.3
Rossner, S.4
Koch, F.5
Romani, N.6
Schuler, G.7
-
25
-
-
51249119868
-
B7-H1 on hepatocytes facilitates priming of specific CD8 T cells but limits the specific recall of primed responses
-
Wahl C, Bochtler P, Chen L, et al. B7-H1 on hepatocytes facilitates priming of specific CD8 T cells but limits the specific recall of primed responses. Gastroenterology. 2008;135:980-988.
-
(2008)
Gastroenterology
, vol.135
, pp. 980-988
-
-
Wahl, C.1
Bochtler, P.2
Chen, L.3
-
26
-
-
64249088830
-
+ T cells are restricted by the up-regulation of PD-1
-
+ T cells are restricted by the up-regulation of PD-1. J Immunol. 2009;182:4244-4254.
-
(2009)
J Immunol
, vol.182
, pp. 4244-4254
-
-
Fuse, S.1
Tsai, C.Y.2
Molloy, M.J.3
-
27
-
-
3142688997
-
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
-
Chemnitz JM, Parry RV, Nichols KE, et al. SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol. 2004;173:945-954. (Pubitemid 38924267)
-
(2004)
Journal of Immunology
, vol.173
, Issue.2
, pp. 945-954
-
-
Chemnitz, J.M.1
Parry, R.V.2
Nichols, K.E.3
June, C.H.4
Riley, J.L.5
-
28
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
DOI 10.1128/MCB.25.21.9543-9553.2005
-
Parry RV, Chemnitz JM, Frauwirth KA, et al. CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol Cell Biol. 2005;25:9543-9553. (Pubitemid 41507854)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.21
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
Lanfranco, A.R.4
Braunstein, I.5
Kobayashi, S.V.6
Linsley, P.S.7
Thompson, C.B.8
Riley, J.L.9
-
29
-
-
33749009709
-
+ T cells leads to reversible immune dysfunction
-
DOI 10.1038/nm1482, PII NM1482
-
Trautmann L, Janbazian L, Chomont N, et al. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med. 2006;12:1198-1202. (Pubitemid 44527357)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
Boulassel, M.-R.7
Delwart, E.8
Sepulveda, H.9
Balderas, R.S.10
Routy, J.-P.11
Haddad, E.K.12
Sekaly, R.-P.13
-
30
-
-
33749338938
-
+ T cell survival in HIV infection
-
DOI 10.1084/jem.20061496
-
Petrovas C, Casazza JP, Brenchley JM, et al. PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med. 2006;203:2281-2292. (Pubitemid 44498363)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.10
, pp. 2281-2292
-
-
Petrovas, C.1
Casazza, J.P.2
Brenchley, J.M.3
Price, D.A.4
Gostick, E.5
Adams, W.C.6
Precopio, M.L.7
Schacker, T.8
Roederer, M.9
Douek, D.C.10
Koup, R.A.11
-
31
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
DOI 10.1038/nature05115, PII NATURE05115
-
Day CL, Kaufmann DE, Kiepiela P, et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006;443:350-354. (Pubitemid 44435155)
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.R.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
32
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Agata Y, Kawasaki A, Nishimura H, et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol. 1996;8:765-772. (Pubitemid 26148299)
-
(1996)
International Immunology
, vol.8
, Issue.5
, pp. 765-772
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
Ishida, Y.4
Tsubata, T.5
Yagita, H.6
Honjo, T.7
-
33
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med. 2000;192:1027-1034.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
-
35
-
-
33748428203
-
T-cell costimulation - Biology, therapeutic potential, and challenges
-
DOI 10.1056/NEJMp068087
-
Sharpe AH, Abbas AK. T-cell costimulation-biology, therapeutic potential, and challenges. N Engl J Med. 2006;355:973-975. (Pubitemid 44343539)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.10
, pp. 973-975
-
-
Sharpe, A.H.1
Abbas, A.K.2
-
36
-
-
11144230063
-
The CD28 family: A T-cell rheostat for therapeutic control of T-cell activation
-
DOI 10.1182/blood-2004-04-1596
-
Riley JL, June CH. The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation. Blood 2005; 105: 13-21. (Pubitemid 40053057)
-
(2005)
Blood
, vol.105
, Issue.1
, pp. 13-21
-
-
Riley, J.L.1
June, C.H.2
-
37
-
-
46749114315
-
Interaction of human PD-L1 and B7-1
-
Butte MJ, Pena-Cruz V, Kim MJ, et al. Interaction of human PD-L1 and B7-1. Mol Immunol. 2008;45:3567-3572.
-
(2008)
Mol Immunol
, vol.45
, pp. 3567-3572
-
-
Butte, M.J.1
Pena-Cruz, V.2
Kim, M.J.3
-
38
-
-
33748881940
-
+ cell activation
-
DOI 10.1002/eji.200635978
-
Kuipers H, Muskens F, Willart M, et al. Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation. Eur J Immunol. 2006;36:2472-2482. (Pubitemid 44420603)
-
(2006)
European Journal of Immunology
, vol.36
, Issue.9
, pp. 2472-2482
-
-
Kuipers, H.1
Muskens, F.2
Willart, M.3
Hijdra, D.4
Van Assema, F.B.J.5
Coyle, A.J.6
Hoogsteden, H.C.7
Lambrecht, B.N.8
-
39
-
-
58149339765
-
B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection
-
Wang X, Zhang Z, Zhang S, et al. B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection. Eur J Immunol. 2008;38:3226-3236.
-
(2008)
Eur J Immunol
, vol.38
, pp. 3226-3236
-
-
Wang, X.1
Zhang, Z.2
Zhang, S.3
-
40
-
-
0033104614
-
TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells
-
Josien R, Wong BR, Li HL, et al. TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells. J Immunol. 1999;162:2562-2568. (Pubitemid 29309274)
-
(1999)
Journal of Immunology
, vol.162
, Issue.5
, pp. 2562-2568
-
-
Josien, R.1
Wong, B.R.2
Li, H.-L.3
Steinman, R.M.4
Choi, Y.5
-
41
-
-
77954497180
-
Cutting edge: Granulocyte-macrophage colony-stimulating factor is the major CD8+ T cell-derived licensing factor for dendritic cell activation
-
Min L, Mohammad Isa SA, Shuai W, et al. Cutting edge: granulocyte-macrophage colony-stimulating factor is the major CD8+ T cell-derived licensing factor for dendritic cell activation. J Immunol. 2010;184:4625-4629.
-
(2010)
J Immunol
, vol.184
, pp. 4625-4629
-
-
Min, L.1
Mohammad Isa, S.A.2
Shuai, W.3
-
42
-
-
0033591679
-
CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivo
-
Ruedl C, Kopf M, Bachmann MF. CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivo. J Exp Med. 1999;189:1875-1884.
-
(1999)
J Exp Med
, vol.189
, pp. 1875-1884
-
-
Ruedl, C.1
Kopf, M.2
Bachmann, M.F.3
-
43
-
-
16544395818
-
The injection of plasmid DNA in mouse muscle results in lifelong persistence of DNA, gene expression, and humoral response
-
DOI 10.1385/MB:27:2:109
-
Armengol G, Ruiz LM, Orduz S. The injection of plasmid DNA in mouse muscle results in lifelong persistence of DNA, gene expression, and humoral response. Mol Biotechnol. 2004;27:109-118. (Pubitemid 41490596)
-
(2004)
Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology
, vol.27
, Issue.2
, pp. 109-118
-
-
Armengol, G.1
Ruiz, L.M.2
Orduz, S.3
-
44
-
-
32444446901
-
Multimeric soluble CB40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines
-
DOI 10.1128/JVI.80.4.1762-1772.2006
-
Stone GW, Barzee S, Snarsky V, et al. Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines. J Virol. 2006;80: 1762-1772. (Pubitemid 43228717)
-
(2006)
Journal of Virology
, vol.80
, Issue.4
, pp. 1762-1772
-
-
Stone, G.W.1
Barzee, S.2
Snarsky, V.3
Kee, K.4
Spina, C.A.5
Yu, X.-F.6
Kornbluth, R.S.7
|