Cannabinoid receptor 1 regulates ERK and GSK-3β-dependent glucocorticoid inhibition of osteoblast differentiation in murine MC3T3-E1 cells

Bone

Volumn 49, Issue 6, 2011, Pages 1255-1263

  Wu, Re Wen ^a,b   Lin, Tzu Ping ^a,b   Ko, Jih Yang ^a,b   Yeh, Da Wei ^a   Chen, Ming Wen ^a   Ke, Huei Ching ^a   Wu, Shin Long ^a   Wang, Feng Sheng ^a,b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Cannabinoid receptor 1; ERK; Glucocorticoid; Osteoblast differentiation; Runx2

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; FORMAZAN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCALCIN; PROTEIN KINASE B; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; BONE MATRIX; BONE MINERAL; CELL ACTIVITY; CELL DIFFERENTIATION; CELL LOSS; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME REPRESSION; MOUSE; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

ANIMALS; APOPTOSIS; BENZOXAZINES; BONE MATRIX; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE KNOCKDOWN TECHNIQUES; GLUCOCORTICOIDS; GLYCOGEN SYNTHASE KINASE 3; MICE; MODELS, BIOLOGICAL; MORPHOLINES; MUTANT PROTEINS; NAPHTHALENES; OSTEOBLASTS; PIPERIDINES; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; RECEPTORS, CANNABINOID; RNA INTERFERENCE;

EID: 81355146697     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.08.022     Document Type: Article

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