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Volumn 10, Issue 2, 2009, Pages 139-147

Cannabinoid Receptor Type 1 Protects against Age- Related Osteoporosis by Regulating Osteoblast and Adipocyte Differentiation in Marrow Stromal Cells

Author keywords

HUMDISEASE; SIGNALING

Indexed keywords

CANNABINOID 1 RECEPTOR; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 67849129193     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2009.07.006     Document Type: Article
Times cited : (148)

References (32)
  • 1
    • 14244250617 scopus 로고    scopus 로고
    • Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation
    • Ali A.A., Weinstein R.S., Stewart S.A., Parfitt A.M., Manolagas S.C., and Jilka R.L. Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology 146 (2005) 1226-1235
    • (2005) Endocrinology , vol.146 , pp. 1226-1235
    • Ali, A.A.1    Weinstein, R.S.2    Stewart, S.A.3    Parfitt, A.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 2
    • 0029880186 scopus 로고    scopus 로고
    • Genetic variability in adult bone density among inbred strains of mice
    • Beamer W.G., Donahue L.R., Rosen C.J., and Baylink D.J. Genetic variability in adult bone density among inbred strains of mice. Bone 18 (1996) 397-403
    • (1996) Bone , vol.18 , pp. 397-403
    • Beamer, W.G.1    Donahue, L.R.2    Rosen, C.J.3    Baylink, D.J.4
  • 3
    • 0026050219 scopus 로고
    • Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
    • Cao Z., Umek R.M., and McKnight S.L. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5 (1991) 1538-1552
    • (1991) Genes Dev. , vol.5 , pp. 1538-1552
    • Cao, Z.1    Umek, R.M.2    McKnight, S.L.3
  • 4
    • 28944453205 scopus 로고    scopus 로고
    • Cannabinoid signalling
    • Demuth D.G., and Molleman A. Cannabinoid signalling. Life Sci. 78 (2006) 549-563
    • (2006) Life Sci. , vol.78 , pp. 549-563
    • Demuth, D.G.1    Molleman, A.2
  • 5
    • 0021840267 scopus 로고
    • Trabecular bone resorption depth decreases with age: differences between normal males and females
    • Eriksen E.F., Mosekilde L., and Melsen F. Trabecular bone resorption depth decreases with age: differences between normal males and females. Bone 6 (1985) 141-146
    • (1985) Bone , vol.6 , pp. 141-146
    • Eriksen, E.F.1    Mosekilde, L.2    Melsen, F.3
  • 6
    • 33846005868 scopus 로고    scopus 로고
    • Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2
    • Fox K.E., Fankell D.M., Erickson P.F., Majka S.M., Crossno Jr. J.T., and Klemm D.J. Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2. J. Biol. Chem. 281 (2006) 40341-40353
    • (2006) J. Biol. Chem. , vol.281 , pp. 40341-40353
    • Fox, K.E.1    Fankell, D.M.2    Erickson, P.F.3    Majka, S.M.4    Crossno Jr., J.T.5    Klemm, D.J.6
  • 10
    • 41049084067 scopus 로고    scopus 로고
    • Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro
    • Idris A.I., Rojas J., Greig I.R., Van't Hof R.J., and Ralston S.H. Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro. Calcif. Tissue Int. 82 (2008) 191-201
    • (2008) Calcif. Tissue Int. , vol.82 , pp. 191-201
    • Idris, A.I.1    Rojas, J.2    Greig, I.R.3    Van't Hof, R.J.4    Ralston, S.H.5
  • 11
    • 54349124546 scopus 로고    scopus 로고
    • Regulation of bone mass, osteoclast function and ovariectomy-induced bone loss by the type 2 cannabinoid receptor
    • Idris A.I., Sophocleous A., Landao-Bassonga E., van't Hof R.J., and Ralston S.H. Regulation of bone mass, osteoclast function and ovariectomy-induced bone loss by the type 2 cannabinoid receptor. Endocrinology 149 (2008) 5619-5626
    • (2008) Endocrinology , vol.149 , pp. 5619-5626
    • Idris, A.I.1    Sophocleous, A.2    Landao-Bassonga, E.3    van't Hof, R.J.4    Ralston, S.H.5
  • 12
    • 0034842784 scopus 로고    scopus 로고
    • Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
    • Justesen J., Stenderup K., Ebbesen E.N., Mosekilde L., Steiniche T., and Kassem M. Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2 (2001) 165-171
    • (2001) Biogerontology , vol.2 , pp. 165-171
    • Justesen, J.1    Stenderup, K.2    Ebbesen, E.N.3    Mosekilde, L.4    Steiniche, T.5    Kassem, M.6
  • 13
    • 0036651815 scopus 로고    scopus 로고
    • Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures
    • Justesen J., Stenderup K., Eriksen E.F., and Kassem M. Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures. Calcif. Tissue Int. 71 (2002) 36-44
    • (2002) Calcif. Tissue Int. , vol.71 , pp. 36-44
    • Justesen, J.1    Stenderup, K.2    Eriksen, E.F.3    Kassem, M.4
  • 16
    • 0018222773 scopus 로고
    • Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age
    • Lips P., Courpron P., and Meunier P.J. Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif. Tissue Res. 26 (1978) 13-17
    • (1978) Calcif. Tissue Res. , vol.26 , pp. 13-17
    • Lips, P.1    Courpron, P.2    Meunier, P.J.3
  • 17
    • 0030826355 scopus 로고    scopus 로고
    • Regulation of spontaneous activity of the delta-opioid receptor: studies of inverse agonism in intact cells
    • Merkouris M., Mullaney I., Georgoussi Z., and Milligan G. Regulation of spontaneous activity of the delta-opioid receptor: studies of inverse agonism in intact cells. J. Neurochem. 69 (1997) 2115-2122
    • (1997) J. Neurochem. , vol.69 , pp. 2115-2122
    • Merkouris, M.1    Mullaney, I.2    Georgoussi, Z.3    Milligan, G.4
  • 18
    • 0015137446 scopus 로고
    • Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies
    • Meunier P., Aaron J., Edouard C., and Vignon G. Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies. Clin. Orthop. Relat. Res. 80 (1971) 147-154
    • (1971) Clin. Orthop. Relat. Res. , vol.80 , pp. 147-154
    • Meunier, P.1    Aaron, J.2    Edouard, C.3    Vignon, G.4
  • 20
    • 0032802188 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid receptor ligands
    • Pertwee R.G. Pharmacology of cannabinoid receptor ligands. Curr. Med. Chem. 6 (1999) 635-664
    • (1999) Curr. Med. Chem. , vol.6 , pp. 635-664
    • Pertwee, R.G.1
  • 21
    • 31044432767 scopus 로고    scopus 로고
    • Pathogenesis of osteoporosis: concepts, conflicts, and prospects
    • Raisz L.G. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J. Clin. Invest. 115 (2005) 3318-3325
    • (2005) J. Clin. Invest. , vol.115 , pp. 3318-3325
    • Raisz, L.G.1
  • 22
    • 1842866963 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
    • Ravinet T.C., Delgorge C., Menet C., Arnone M., and Soubrié P. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int. J. Obes. Relat. Metab. Disord. 28 (2004) 640-648
    • (2004) Int. J. Obes. Relat. Metab. Disord. , vol.28 , pp. 640-648
    • Ravinet, T.C.1    Delgorge, C.2    Menet, C.3    Arnone, M.4    Soubrié, P.5
  • 23
    • 0033982177 scopus 로고    scopus 로고
    • CREB activation induces adipogenesis in 3T3-L1 cells
    • Reusch J.E., Colton L.A., and Klemm D.J. CREB activation induces adipogenesis in 3T3-L1 cells. Mol. Cell. Biol. 20 (2000) 1008-1020
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1008-1020
    • Reusch, J.E.1    Colton, L.A.2    Klemm, D.J.3
  • 24
    • 0019942628 scopus 로고
    • Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes
    • Riggs B.L., Wahner H.W., Seeman E., Offord K.P., Dunn W.L., Mazess R.B., Johnson K.A., and Melton III L.J. Changes in bone mineral density of the proximal femur and spine with aging. Differences between the postmenopausal and senile osteoporosis syndromes. J. Clin. Invest. 70 (1982) 716-723
    • (1982) J. Clin. Invest. , vol.70 , pp. 716-723
    • Riggs, B.L.1    Wahner, H.W.2    Seeman, E.3    Offord, K.P.4    Dunn, W.L.5    Mazess, R.B.6    Johnson, K.A.7    Melton III, L.J.8
  • 28
    • 0032849244 scopus 로고    scopus 로고
    • Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation
    • Tintut Y., Parhami F., Le V., Karsenty G., and Demer L.L. Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation. J. Biol. Chem. 274 (1999) 28875-28879
    • (1999) J. Biol. Chem. , vol.274 , pp. 28875-28879
    • Tintut, Y.1    Parhami, F.2    Le, V.3    Karsenty, G.4    Demer, L.L.5
  • 29
    • 0038725728 scopus 로고    scopus 로고
    • Osteoclast formation in the mouse coculture assay
    • Helfrich M.H., and Ralston S.H. (Eds), Humana Press, Totowa
    • van't Hof R.J. Osteoclast formation in the mouse coculture assay. In: Helfrich M.H., and Ralston S.H. (Eds). Bone Research Protocols (2003), Humana Press, Totowa 145-152
    • (2003) Bone Research Protocols , pp. 145-152
    • van't Hof, R.J.1
  • 30
    • 0036724870 scopus 로고    scopus 로고
    • Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis
    • Verma S., Rajaratnam J.H., Denton J., Hoyland J.A., and Byers R.J. Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis. J. Clin. Pathol. 55 (2002) 693-698
    • (2002) J. Clin. Pathol. , vol.55 , pp. 693-698
    • Verma, S.1    Rajaratnam, J.H.2    Denton, J.3    Hoyland, J.A.4    Byers, R.J.5
  • 31
    • 0023033281 scopus 로고
    • Pertussis toxin blocks the inhibitory effects of somatostatin on cAMP-dependent vasoactive intestinal peptide and cAMP-independent thyrotropin releasing hormone-stimulated prolactin secretion of GH3 cells
    • Yajima Y., Akita Y., and Saito T. Pertussis toxin blocks the inhibitory effects of somatostatin on cAMP-dependent vasoactive intestinal peptide and cAMP-independent thyrotropin releasing hormone-stimulated prolactin secretion of GH3 cells. J. Biol. Chem. 261 (1986) 2684-2689
    • (1986) J. Biol. Chem. , vol.261 , pp. 2684-2689
    • Yajima, Y.1    Akita, Y.2    Saito, T.3
  • 32
    • 45249122818 scopus 로고    scopus 로고
    • cAMP/PKA regulates osteogenesis, adipogenesis and ratio of RANKL/OPG mRNA expression in mesenchymal stem cells by suppressing leptin
    • Yang D.C., Tsay H.J., Lin S.Y., Chiou S.H., Li M.J., Chang T.J., and Hung S.C. cAMP/PKA regulates osteogenesis, adipogenesis and ratio of RANKL/OPG mRNA expression in mesenchymal stem cells by suppressing leptin. PLoS ONE 3 (2008) e1540
    • (2008) PLoS ONE , vol.3
    • Yang, D.C.1    Tsay, H.J.2    Lin, S.Y.3    Chiou, S.H.4    Li, M.J.5    Chang, T.J.6    Hung, S.C.7


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