Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line

Diabetologia

Volumn 54, Issue 6, 2011, Pages 1567-1578

  El Remessy, A B ^a,b   Rajesh, M ^c   Mukhopadhyay, P ^c   Horvath B ^c,d   Patel, V ^c   Al Gayyar, M M H ^a,b   Pillai, B A ^a,b   Pacher, P ^c  

^a UNIVERSITY OF GEORGIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Apoptosis; Cannabinoid; CB 1; ICAM 1; NF B; Rimonabant; SR141716; VCAM 1

Indexed keywords

3 NITROTYROSINE; CANNABINOID 1 RECEPTOR; CASPASE 3; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; RIMONABANT; STREPTOZOCIN; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; DRUG ACTIVITY; ENZYME ACTIVATION; GENE DELETION; HUMAN; HUMAN CELL; NITRATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RETINA CELL; TISSUE ADHESION; VASCULITIS; ANIMAL; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GENETICS; MALE; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA; RETINA VASCULITIS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; GLUCOSE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTOR, CANNABINOID, CB1; RETINA; RETINAL VASCULITIS; SIGNAL TRANSDUCTION; STREPTOZOCIN;

EID: 80052547791     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2061-4     Document Type: Article

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