-
1
-
-
18844450441
-
The search for safer glucocorticoid receptor ligands
-
DOI 10.1210/er.2005-0002
-
Rosen, J., and Miner, J. N. (2005) The search for safer glucocorticoid receptor ligands. Endocr. Rev. 26, 452-464 (Pubitemid 40691300)
-
(2005)
Endocrine Reviews
, vol.26
, Issue.3
, pp. 452-464
-
-
Rosen, J.1
Miner, J.N.2
-
2
-
-
36748999972
-
Glucocorticoid-induced osteoporosis
-
DOI 10.1097/MED.0b013e3282f15407, PII 0126602920071200000005
-
Berris, K. K., Repp, A. L., and Kleerekoper, M. (2007) Glucocorticoid-induced osteoporosis. Curr. Opin. Endocrinol. Diabetes Obes. 14, 446-450 (Pubitemid 350214011)
-
(2007)
Current Opinion in Endocrinology, Diabetes and Obesity
, vol.14
, Issue.6
, pp. 446-450
-
-
Berris, K.K.1
Repp, A.L.2
Kleerekoper, M.3
-
3
-
-
77955445061
-
From bone biology to clinical outcome: State of the art and future perspectives
-
Schett, G., Saag, K. G., and Bijlsma, J. W. J. (2010) From bone biology to clinical outcome: state of the art and future perspectives. Ann. Rheum. Dis. 69, 1415-1419
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 1415-1419
-
-
Schett, G.1
Saag, K.G.2
Bijlsma, J.W.J.3
-
4
-
-
0030925683
-
Steroid receptor interactions with heat shock protein and immunophilin chaperones
-
DOI 10.1210/er.18.3.306
-
Pratt, W. B., and Toft, D. O. (1997) Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 18, 306-360 (Pubitemid 27246880)
-
(1997)
Endocrine Reviews
, vol.18
, Issue.3
, pp. 306-360
-
-
Pratt, W.B.1
Toft, D.O.2
-
5
-
-
73249115366
-
Crosstalk in inflammation: The interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases
-
Beck, I. M., Vanden Berghe, W., Vermeulen, L., Yamamoto, K. R., Haegeman, G., and De Bosscher, K. (2009) Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. Endocr. Rev. 30, 830-882
-
(2009)
Endocr. Rev.
, vol.30
, pp. 830-882
-
-
Beck, I.M.1
Vanden Berghe, W.2
Vermeulen, L.3
Yamamoto, K.R.4
Haegeman, G.5
De Bosscher, K.6
-
6
-
-
0031459881
-
Glucocorticoid-mediated repression of nuclear factor-κB-dependent transcription involves direct interference with transactivation
-
DOI 10.1073/pnas.94.25.13504
-
De Bosscher, K., Schmitz, M. L., Vanden Berghe, W., Plaisance, S., Fiers, W., and Haegeman, G. (1997) Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation. Proc. Natl. Acad. Sci. U. S. A. 94, 13504-13509 (Pubitemid 28009612)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.25
, pp. 13504-13509
-
-
De Bosscher, K.1
Schmitz, M.L.2
Vanden Berghe, W.3
Plaisance, S.4
Fiers, W.5
Haegeman, G.6
-
7
-
-
0034665748
-
The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
-
Nissen, R. M., and Yamamoto, K. R. (2000) The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev. 14, 2314-2329
-
(2000)
Genes Dev.
, vol.14
, pp. 2314-2329
-
-
Nissen, R.M.1
Yamamoto, K.R.2
-
8
-
-
0041324898
-
The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: Molecular mechanisms for gene repression
-
DOI 10.1210/er.2002-0006
-
De Bosscher, K., Vanden Berghe, W., and Haegeman, G. (2003) The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. Endocr. Rev. 24, 488-522 (Pubitemid 37059110)
-
(2003)
Endocrine Reviews
, vol.24
, Issue.4
, pp. 488-522
-
-
De Bosscher, K.1
Vanden Berghe, W.2
Haegeman, G.3
-
9
-
-
42649143599
-
Therapeutic implications of the nuclear factor-kappaB/nuclear receptor cross-talk
-
DOI 10.2741/2997
-
Gossye, V., Haegeman, G., and De Bosscher, K. (2008) Therapeutic implications of the nuclear factor-kappaB/nuclear receptor cross-talk. Front. Biosci. 13, 4122-4143 (Pubitemid 351599679)
-
(2008)
Frontiers in Bioscience
, vol.13
, Issue.11
, pp. 4122-4143
-
-
Gossye, V.1
Haegeman, G.2
De Bosscher, K.3
-
10
-
-
34548554688
-
Glucocorticoid-induced osteoporosis: Pathophysiology and therapy
-
DOI 10.1007/s00198-007-0394-0
-
Canalis, E., Mazziotti, G., Giustina, A., and Bilezikian, J. P. (2007) Glucocorticoid-induced osteoporosis: pathophysiology and therapy. Osteoporos. Int. 18, 1319-1328 (Pubitemid 47389469)
-
(2007)
Osteoporosis International
, vol.18
, Issue.10
, pp. 1319-1328
-
-
Canalis, E.1
Mazziotti, G.2
Giustina, A.3
Bilezikian, J.P.4
-
11
-
-
33751501004
-
Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density
-
DOI 10.1210/en.2006-0459
-
Jia, D., O'Brien, C. A., Stewart, S. A., Manolagas, S. C., and Weinstein, R. S. (2006) Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density. Endocrinology 147, 5592-5599 (Pubitemid 44833476)
-
(2006)
Endocrinology
, vol.147
, Issue.12
, pp. 5592-5599
-
-
Jia, D.1
O'Brien, C.A.2
Stewart, S.A.3
Manolagas, S.C.4
Weinstein, R.S.5
-
12
-
-
33745138231
-
Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-κB (NF-κB) ligand, osteoprotegerin, and receptor activator of NF-κB in mouse calvarial bones
-
DOI 10.1210/en.2005-0717
-
Swanson, C., Lorentzon, M., Conaway, H. H., and Lerner, U. H. (2006) Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvarial bones. Endocrinology 147, 3613-3622 (Pubitemid 43901154)
-
(2006)
Endocrinology
, vol.147
, Issue.7
, pp. 3613-3622
-
-
Swanson, C.1
Lorentzon, M.2
Conaway, H.H.3
Lerner, U.H.4
-
13
-
-
0032528180
-
Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts end osteocytes by glucocorticoids potential mechanisms of their deleterious effects on bone
-
Weinstein, R. S., Jilka, R. L., Parfitt, A. M., and Manolagas, S. C. (1998) Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J. Clin. Invest. 102, 274-282 (Pubitemid 28335186)
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.2
, pp. 274-282
-
-
Weinstein, R.S.1
Jilka, R.L.2
Michael Parfitt, A.3
Manolagas, S.C.4
-
14
-
-
0034733664
-
Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle: Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes
-
DOI 10.1074/jbc.M001758200
-
Smith, E., Redman, R. A., Logg, C. R., Coetzee, G. A., Kasahara, N., and Frenkel, B. (2000) Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes. J. Biol. Chem. 275, 19992-20001 (Pubitemid 30441607)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.26
, pp. 19992-20001
-
-
Smith, E.1
Redman, R.A.2
Logg, C.R.3
Coetzee, G.A.4
Kasahara, N.5
Frenkel, B.6
-
15
-
-
77956277161
-
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor
-
Rauch, A., Seitz, S., Baschant, U., Schilling, A. F., Illing, A., Stride, B., Kirilov, M., Mandic, V., Takacz, A., Schmidt-Ullrich, R., Ostermay, S., Schinke, T., Spanbroek, R., Zaiss, M. M., Angel, P. E., Lerner, U. H., David, J.-P., Reichardt, H. M., Amling, M., Schütz, G., and Tuckermann, J. P. (2010) Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor. Cell Metab. 11, 517-531
-
(2010)
Cell. Metab.
, vol.11
, pp. 517-531
-
-
Rauch, A.1
Seitz, S.2
Baschant, U.3
Schilling, A.F.4
Illing, A.5
Stride, B.6
Kirilov, M.7
Mandic, V.8
Takacz, A.9
Schmidt-Ullrich, R.10
Ostermay, S.11
Schinke, T.12
Spanbroek, R.13
Zaiss, M.M.14
Angel, P.E.15
Lerner, U.H.16
David, J.-P.17
Reichardt, H.M.18
Amling, M.19
Schütz, G.20
Tuckermann, J.P.21
more..
-
16
-
-
18144444807
-
DNA binding of the glucocorticoid receptor is not essential for survival
-
DOI 10.1016/S0092-8674(00)81183-6
-
Reichardt, H. M., Kaestner, K. H., Tuckermann, J., Kretz, O., Wessely, O., Bock, R., Gass, P., Schmid, W., Herrlich, P., Angel, P., and Schutz, G. (1998) DNA binding of the glucocorticoid receptor is not essential for survival. Cell 93, 531-541 (Pubitemid 28240715)
-
(1998)
Cell
, vol.93
, Issue.4
, pp. 531-541
-
-
Reichardt, H.M.1
Kaestner, K.H.2
Tuckermann, J.3
Kretz, O.4
Wessely, O.5
Bock, R.6
Gass, P.7
Schmid, W.8
Herrlich, P.9
Angel, P.10
Schutz, G.11
-
17
-
-
77953063043
-
Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor
-
Frijters, R., Fleuren, W., Toonen, E. J. M., Tuckermann, J. P., Reichardt, H. M., van der Maaden, H., van Elsas, A., van Lierop, M.-J., Dokter, W., de Vlieg, J., and Alkema, W. (2010) Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor. BMC Genomics 11, 359
-
(2010)
BMC Genomics
, vol.11
, pp. 359
-
-
Frijters, R.1
Fleuren, W.2
Toonen, E.J.M.3
Tuckermann, J.P.4
Reichardt, H.M.5
Van Der Maaden, H.6
Van Elsas, A.7
Van Lierop, M.-J.8
Dokter, W.9
De Vlieg, J.10
Alkema, W.11
-
18
-
-
77952951936
-
The role of the glucocorticoid receptor in inflammation and immunity
-
Baschant, U., and Tuckermann, J. (2010) The role of the glucocorticoid receptor in inflammation and immunity. J. Steroid Biochem. Mol. Biol. 120, 69-75
-
(2010)
J. Steroid Biochem. Mol. Biol.
, vol.120
, pp. 69-75
-
-
Baschant, U.1
Tuckermann, J.2
-
19
-
-
40849142555
-
A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis
-
Dewint, P., Gossye, V., De Bosscher, K., Vanden Berghe, W., Van Beneden, K., Deforce, D., Van Calenbergh, S., Müller-Ladner, U., Vander Cruyssen, B., Verbruggen, G., Haegeman, G., and Elewaut, D. (2008) A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis. J. Immunol. 180, 2608-2615
-
(2008)
J. Immunol.
, vol.180
, pp. 2608-2615
-
-
Dewint, P.1
Gossye, V.2
De Bosscher, K.3
Vanden Berghe, W.4
Van Beneden, K.5
Deforce, D.6
Van Calenbergh, S.7
Müller-Ladner, U.8
Vander Cruyssen, B.9
Verbruggen, G.10
Haegeman, G.11
Elewaut, D.12
-
20
-
-
27644492383
-
A fully dissociated compound of plant origin for inflammatory gene repression
-
DOI 10.1073/pnas.0505554102
-
De Bosscher, K., Vanden Berghe, W., Beck, I. M., Van Molle, W., Hennuyer, N., Hapgood, J., Libert, C., Staels, B., Louw, A., and Haegeman, G. (2005) A fully dissociated compound of plant origin for inflammatory gene repression. Proc. Natl. Acad. Sci. U. S. A. 102, 15827-15832 (Pubitemid 41552827)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.44
, pp. 15827-15832
-
-
De Bosscher, K.1
Berghe, W.V.2
Beck, I.M.E.3
Van Molle, W.4
Hennuyer, N.5
Hapgood, J.6
Libert, C.7
Staels, B.8
Louw, A.9
Haegeman, G.10
-
21
-
-
77949524864
-
Therapeutic and adverse effects of a nonsteroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis
-
Wüst, S., Tischner, D., John, M., Tuckermann, J. P., Menzfeld, C., Hanisch, U.-K., van den Brandt, J., Lühder, F., and Reichardt, H. M. (2009) Therapeutic and adverse effects of a nonsteroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis. PLoS ONE 4, e8202
-
(2009)
PLoS ONE
, vol.4
-
-
Wüst, S.1
Tischner, D.2
John, M.3
Tuckermann, J.P.4
Menzfeld, C.5
Hanisch, U.-K.6
Van Den Brandt, J.7
Lühder, F.8
Reichardt, H.M.9
-
22
-
-
75149156175
-
Anti-inflammatory properties of a plantderived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis
-
Van Loo, G., Sze, M., Bougarne, N., Praet, J., McGuire, C., Ullrich, A., Haegeman, G., Prinz, M., Beyaert, R., and De Bosscher, K. (2009) Anti-inflammatory properties of a plantderived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis. Mol. Endocrinol., 24, 1-13
-
(2009)
Mol. Endocrinol.
, vol.24
, pp. 1-13
-
-
Van Loo, G.1
Sze, M.2
Bougarne, N.3
Praet, J.4
McGuire, C.5
Ullrich, A.6
Haegeman, G.7
Prinz, M.8
Beyaert, R.9
De Bosscher, K.10
-
23
-
-
70349247894
-
Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects
-
Zhang, Z., Zhang, Z. Y., and Schluesener, H. J. (2009) Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects. J. Immunol. 183, 3081-3091
-
(2009)
J. Immunol.
, vol.183
, pp. 3081-3091
-
-
Zhang, Z.1
Zhang, Z.Y.2
Schluesener, H.J.3
-
24
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett, F. C., Edworthy, S. M., Bloch, D. A., McShane, D. J., Fries, J. F., Cooper, N. S., Healey, L. A., Kaplan, S. R., Liang, M. H., Luthra, H. S., Medsger, T. A., Jr., Mitchell, D. M., Neustadt, D. H., Pinals, R. S., Schaller, J. G., Sharp, J. T., Wilder, R. L., and Hunder, G. G. (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31, 315-324 (Pubitemid 18091653)
-
(1988)
Arthritis and Rheumatism
, vol.31
, Issue.3
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
McShane, D.J.4
Fries, J.F.5
Cooper, N.S.6
Healey, L.A.7
Kaplan, S.R.8
Liang, M.H.9
Luthra, H.S.10
Medsger Jr., T.A.11
Mitchell, D.M.12
Neustadt, D.H.13
Pinals, R.S.14
Schaller, J.G.15
Sharp, J.T.16
Wilder, R.L.17
Hunder, G.G.18
-
25
-
-
70350523976
-
Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts
-
Gossye, V., Elewaut, D., Bougarne, N., Bracke, D., Van Calenbergh, S., Haegeman, G., and De Bosscher, K. (2009) Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum. 60, 3241-3250
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 3241-3250
-
-
Gossye, V.1
Elewaut, D.2
Bougarne, N.3
Bracke, D.4
Van Calenbergh, S.5
Haegeman, G.6
De Bosscher, K.7
-
26
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
28
-
-
42549123138
-
Dissociated non-steroidal glucocorticoid receptor modulators: An update on new compounds
-
DOI 10.1517/13543776.18.3.339
-
Schäcke, H., Berger, M., Hansson, T. G., McKerrecher, D., and Rehwinkel, H. (2008) Dissociated non-steroidal glucocorticoid receptor modulators: an update on new compounds. Expert Opin. Ther. Patents 18, 339-352 (Pubitemid 351577865)
-
(2008)
Expert Opinion on Therapeutic Patents
, vol.18
, Issue.3
, pp. 339-352
-
-
Schacket, H.1
Berger, M.2
Hansson, T.G.3
McKerrecher, D.4
Rehwinkel, H.5
-
29
-
-
34547887674
-
Selective glucocorticoid receptor agonists (SEGRAs): Novel ligands with an improved therapeutic index
-
DOI 10.1016/j.mce.2007.05.014, PII S0303720707002134
-
Schäcke, H., Berger, M. H. R., and Asadullah, K. (2007) Selective Glucocorticoid Receptor Agonists (SEGRAs): Novel ligands with an improved therapeutic index. Mol. Cell. Endocrinol. 275, 109-117 (Pubitemid 47259282)
-
(2007)
Molecular and Cellular Endocrinology
, vol.275
, Issue.1-2
, pp. 109-117
-
-
Schacke, H.1
Berger, M.2
Rehwinkel, H.3
Asadullah, K.4
-
30
-
-
0029855587
-
Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice
-
Müller-Ladner, U., Kriegsmann, J., Franklin, B. N., Matsumoto, S., Geiler, T., Gay, R. E., and Gay, S. (1996) Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. Am. J. Pathol. 149, 1607-1615 (Pubitemid 26363967)
-
(1996)
American Journal of Pathology
, vol.149
, Issue.5
, pp. 1607-1615
-
-
Muller-Ladner, U.1
Kriegsmann, J.2
Franklin, B.N.3
Matsumoto, S.4
Geiler, T.5
Gay, R.E.6
Gay, S.7
-
31
-
-
23044448407
-
Insights into the role of fibroblasts in human autoimmune diseases
-
DOI 10.1111/j.1365-2249.2005.02824.x
-
Smith, T. J. (2005) Insights into the role of fibroblasts in human autoimmune diseases. Clin. Exp. Immunol. 141, 388-397 (Pubitemid 41075861)
-
(2005)
Clinical and Experimental Immunology
, vol.141
, Issue.3
, pp. 388-397
-
-
Smith, T.J.1
-
32
-
-
0034050781
-
Activation of synoviocytes
-
DOI 10.1097/00002281-200005000-00005
-
Müller-Ladner, U., Gay, R. E., and Gay, S. (2000) Activation of synoviocytes. Curr. Opin. Rheumatol. 12, 186-194 (Pubitemid 30238386)
-
(2000)
Current Opinion in Rheumatology
, vol.12
, Issue.3
, pp. 186-194
-
-
Muller-Ladner, U.1
Gay, R.E.2
Gay, S.3
-
33
-
-
27444446925
-
Are fibroblasts involved in joint destruction?
-
DOI 10.1136/ard.2005.042424
-
Pap, T., Meinecke, I., Müller-Ladner, U., and Gay, S. (2005) Are fibroblasts involved in joint destruction? Ann. Rheum. Dis. 64 (Suppl. 4), iv52-iv54 (Pubitemid 41532019)
-
(2005)
Annals of the Rheumatic Diseases
, vol.64
, Issue.SUPPL. 4
-
-
Pap, T.1
Meinecke, I.2
Muller-Ladner, U.3
Gay, S.4
-
34
-
-
0035185895
-
Cathepsin K is a critical protease in synovial fibroblast-mediated collagen degradation
-
Hou, W. S., Li, Z., Gordon, R. E., Chan, K., Klein, M. J., Levy, R., Keysser, M., Keyszer, G., and Bromme, D. (2001) Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation. Am. J. Pathol. 159, 2167-2177 (Pubitemid 33104271)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.6
, pp. 2167-2177
-
-
Hou, W.-S.1
Li, Z.2
Gordon, R.E.3
Chan, K.4
Klein, M.J.5
Levy, R.6
Keysser, M.7
Keyszer, G.8
Bromme, D.9
-
35
-
-
0028358343
-
Constitutive mRNA and protein production of macrophage colony-stimulating factor but not of other cytokines by synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients
-
Seitz, M., Loetscher, P., Fey, M. F., and Tobler, A. (1994) Constitutive mRNA and protein production of macrophage colony-stimulating factor but not of other cytokines by synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients. Br. J. Rheumatol. 33, 613-619 (Pubitemid 24222111)
-
(1994)
British Journal of Rheumatology
, vol.33
, Issue.7
, pp. 613-619
-
-
Seitz, M.1
Loetscher, P.2
Fey, M.F.3
Tobler, A.4
-
36
-
-
0033768507
-
Expression of osteoclast differentiation factor in rheumatoid arthritis
-
Shigeyama, Y., Pap, T., Kunzler, P., Simmen, B. R., Gay, R. E., and Gay, S. (2000) Expression of osteoclast differentiation factor in rheumatoid arthritis. Arthritis Rheum. 43, 2523-2530
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 2523-2530
-
-
Shigeyama, Y.1
Pap, T.2
Kunzler, P.3
Simmen, B.R.4
Gay, R.E.5
Gay, S.6
-
37
-
-
73449098948
-
A plant-derived glucocorticoid receptor modulator attenuates inflammation without provoking ligand-induced resistance
-
Gossye, V., Elewaut, D., Van Beneden, K., Dewint, P., Haegeman, G., and De Bosscher, K. (2010) A plant-derived glucocorticoid receptor modulator attenuates inflammation without provoking ligand-induced resistance. Ann. Rheum. Dis. 69, 291-296
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 291-296
-
-
Gossye, V.1
Elewaut, D.2
Van Beneden, K.3
Dewint, P.4
Haegeman, G.5
De Bosscher, K.6
-
38
-
-
38149088611
-
Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels
-
Kondo, T., Kitazawa, R., Yamaguchi, A., and Kitazawa, S. (2008) Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels. J. Cell. Biochem. 103, 335-345
-
(2008)
J. Cell. Biochem.
, vol.103
, pp. 335-345
-
-
Kondo, T.1
Kitazawa, R.2
Yamaguchi, A.3
Kitazawa, S.4
-
39
-
-
0033029291
-
Osteopetrosis in cathepsin K-deficient mice
-
DOI 10.1530/eje.0.1400376
-
Hofbauer, L. C., and Heufelder, A. E. (1999) Osteopetrosis in cathepsin K-deficient mice. Eur. J. Endocrinol. 140, 376-377 (Pubitemid 29254000)
-
(1999)
European Journal of Endocrinology
, vol.140
, Issue.5
, pp. 376-377
-
-
Hofbauer, L.C.1
Heufelder, A.E.2
-
40
-
-
33746715059
-
Glucocorticoids suppress bone formation via the osteoclast
-
DOI 10.1172/JCI28084
-
Kim, H. J., Zhao, H., Kitaura, H., Bhattacharyya, S., Brewer, J. A., Muglia, L. J., Ross, F. P., and Teitelbaum, S. L. (2006) Glucocorticoids suppress bone formation via the osteoclast. J. Clin. Invest. 116, 2152-2160 (Pubitemid 44162324)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.8
, pp. 2152-2160
-
-
Kim, H.-J.1
Zhao, H.2
Kitaura, H.3
Bhattacharyya, S.4
Brewer, J.A.5
Muglia, L.J.6
Ross, F.P.7
Teitelbaum, S.L.8
-
41
-
-
12444276298
-
A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects
-
DOI 10.1210/me.2002-0355
-
Coghlan, M. J., Jacobson, P. B., Lane, B., Nakane, M., Lin, C. W., Elmore, S. W., Kym, P. R., Luly, J. R., Carter, G. W., Turner, R., Tyree, C. M., Hu, J., Elgort, M., Rosen, J., and Miner, J. N. (2003) A novel anti-inflammatory maintains glucocorticoid efficacy with reduced side effects. Mol. Endocrinol. 17, 860-869 (Pubitemid 36546214)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.5
, pp. 860-869
-
-
Coghlan, M.J.1
Jacobson, P.B.2
Lane, B.3
Nakane, M.4
Lin, C.W.5
Elmore, S.W.6
Kym, P.R.7
Luly, J.R.8
Carter, G.W.9
Turner, R.10
Tyree, C.M.11
Hu, J.12
Elgort, M.13
Rosen, J.14
Miner, J.N.15
-
42
-
-
33646113165
-
Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells
-
Humphrey, E. L., Williams, J. H., Davie, M. W., and Marshall, M. J. (2006) Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells. Bone 38, 652-661
-
(2006)
Bone
, vol.38
, pp. 652-661
-
-
Humphrey, E.L.1
Williams, J.H.2
Davie, M.W.3
Marshall, M.J.4
-
43
-
-
78650850288
-
Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells
-
Rauner, M., Goettsch, C., Stein, N., Thiele, S., Bornhaeuser, M., De Bosscher, K., Haegeman, G., Tuckermann, J., and Hofbauer, L. C. (2011) Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells. Endocrinology 152, 103-112
-
(2011)
Endocrinology
, vol.152
, pp. 103-112
-
-
Rauner, M.1
Goettsch, C.2
Stein, N.3
Thiele, S.4
Bornhaeuser, M.5
De Bosscher, K.6
Haegeman, G.7
Tuckermann, J.8
Hofbauer, L.C.9
-
44
-
-
38349184205
-
Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling
-
Zhou, H., Mak, W., Zheng, Y., Dunstan, C. R., and Seibel, M. J. (2008) Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling. J. Biol. Chem. 283, 1936-1945
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1936-1945
-
-
Zhou, H.1
Mak, W.2
Zheng, Y.3
Dunstan, C.R.4
Seibel, M.J.5
-
45
-
-
67349094534
-
Endogenous glucocorticoid signaling in osteoblasts is necessary to maintain normal bone structure in mice
-
Kalak, R., Zhou, H., Street, J., Day, R. E., Modzelewski, J. R., Spies, C. M., Liu, P. Y., Li, G., Dunstan, C. R., and Seibel, M. J. (2009) Endogenous glucocorticoid signaling in osteoblasts is necessary to maintain normal bone structure in mice. Bone 45, 61-67
-
(2009)
Bone
, vol.45
, pp. 61-67
-
-
Kalak, R.1
Zhou, H.2
Street, J.3
Day, R.E.4
Modzelewski, J.R.5
Spies, C.M.6
Liu, P.Y.7
Li, G.8
Dunstan, C.R.9
Seibel, M.J.10
-
46
-
-
33746599062
-
A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation
-
DOI 10.1016/j.bone.2006.02.074, PII S8756328206003516
-
Itoh, S., Udagawa, N., Takahashi, N., Yoshitake, F., Narita, H., Ebisu, S., and Ishihara, K. (2006) A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation. Bone 39, 505-512 (Pubitemid 44149269)
-
(2006)
Bone
, vol.39
, Issue.3
, pp. 505-512
-
-
Itoh, S.1
Udagawa, N.2
Takahashi, N.3
Yoshitake, F.4
Narita, H.5
Ebisu, S.6
Ishihara, K.7
-
47
-
-
2142650270
-
Decreased AP-1 activity and interleukin-11 expression by bone marrow stromal cells may be associated with impaired bone formation in aged mice
-
DOI 10.1359/jbmr.2003.18.8.1461
-
Tohjima, E., Inoue, D., Yamamoto, N., Kido, S., Ito, Y., Kato, S., Takeuchi, Y., Fukumoto, S., and Matsumoto, T. (2003) Decreased AP-1 activity and interleukin-11 expression by bone marrow stromal cells may be associated with impaired bone formation in aged mice. J. Bone Miner. Res. 18, 1461-1470 (Pubitemid 41070800)
-
(2003)
Journal of Bone and Mineral Research
, vol.18
, Issue.8
, pp. 1461-1470
-
-
Tohjima, E.1
Inoue, D.2
Yamamoto, N.3
Kido, S.4
Ito, Y.5
Kato, S.6
Takeuchi, Y.7
Fukumoto, S.8
Matsumoto, T.9
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