Serotonergic 5-HT2B receptor controls tissue-nonspecific alkaline phosphatase activity in osteoblasts via eicosanoids and phosphatidylinositol-specific phospholipase C

Journal of Biological Chemistry

Volumn 285, Issue 34, 2010, Pages 26066-26073

  Baudry, Anne ^a   Bitard, Juliette ^a   Mouillet Richard, Sophie ^a   Locker, Morgane ^a   Poliard, Anne ^a   Launay, Jean Marie ^b,c   Kellermann, Odile ^a  

^a INSERM   (France)

^b HÔPITAL LARIBOISIÈRE   (France)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ALKALINE PHOSPHATASE ACTIVITY; BONE HOMEOSTASIS; DOWNSTREAM TARGET; EICOSANOIDS; EXTRACELLULAR MATRIX DEPOSITION; FUNCTIONAL LINKS; INTRINSIC ACTIVITIES; MINERAL DEPOSITIONS; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; OSTEOPROGENITOR CELLS; PHARMACOLOGICAL INHIBITION; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PHOSPHOLIPASES; TIME WINDOWS; WORK FOCUS;

CELL CULTURE; DEFECTS; ENDOTHELIAL CELLS; PRODUCTION; SILICATE MINERALS;

PHOSPHATASES;

ALKALINE PHOSPHATASE; ICOSANOID; LEVAMISOLE; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL LYASE; PHOSPHOLIPASE A2; PROSTAGLANDIN SYNTHASE; RITANSERIN; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN 2C RECEPTOR; SHORT HAIRPIN RNA; VANADIC ACID;

ANIMAL CELL; ARTICLE; BONE MINERALIZATION; CALVARIA; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; MOUSE; NEWBORN; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ALKALINE PHOSPHATASE; ANIMALS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELLS, CULTURED; EICOSANOIDS; LEUKOTRIENES; MICE; OSTEOBLASTS; OSTEOGENESIS; PHOSPHOINOSITIDE PHOSPHOLIPASE C; RECEPTOR, SEROTONIN, 5-HT2B; TIME FACTORS;

MUS;

EID: 77956198308     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.073791     Document Type: Article

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