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Volumn 27, Issue 20, 2007, Pages 7143-7160

Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 6; DEXAMETHASONE; DOXYCYCLINE; GLUCOCORTICOID RECEPTOR; GRANZYME A; ISOPROTEIN;

EID: 35148835555     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00253-07     Document Type: Article
Times cited : (140)

References (35)
  • 1
    • 0028034209 scopus 로고
    • Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme
    • Albiston, A. L., V. R. Obeyesekere, R. E. Smith, and Z. S. Krozowski. 1994. Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme. Mol. Cell. Endocrinol. 105:R11-R17.
    • (1994) Mol. Cell. Endocrinol , vol.105
    • Albiston, A.L.1    Obeyesekere, V.R.2    Smith, R.E.3    Krozowski, Z.S.4
  • 3
    • 0029757679 scopus 로고    scopus 로고
    • Bronnegard, M. 1996. Steroid receptor number. Individual variation and downregulation by treatment. Am. J. Respir. Crit. Care Med. 154:S28-S32, S32-S33.
    • Bronnegard, M. 1996. Steroid receptor number. Individual variation and downregulation by treatment. Am. J. Respir. Crit. Care Med. 154:S28-S32, S32-S33.
  • 4
    • 14244258303 scopus 로고    scopus 로고
    • Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3′-kinase signaling pathway
    • Chrysis, D., F. Zaman, A. S. Chagin, M. Takigawa, and L. Savendahl. 2005. Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3′-kinase signaling pathway. Endocrinology 146:1391-1397.
    • (2005) Endocrinology , vol.146 , pp. 1391-1397
    • Chrysis, D.1    Zaman, F.2    Chagin, A.S.3    Takigawa, M.4    Savendahl, L.5
  • 5
    • 0242380356 scopus 로고    scopus 로고
    • Dexamethasone induces caspase activation in murine osteoblastic MC3T3-E1 cells
    • Chua, C. C., B. H. Chua, Z. Chen, C. Landy, and R. C. Hamdy. 2003. Dexamethasone induces caspase activation in murine osteoblastic MC3T3-E1 cells. Biochim. Biophys. Acta 1642:79-85.
    • (2003) Biochim. Biophys. Acta , vol.1642 , pp. 79-85
    • Chua, C.C.1    Chua, B.H.2    Chen, Z.3    Landy, C.4    Hamdy, R.C.5
  • 6
    • 0025131067 scopus 로고
    • Novel antipeptide antibodies to the human glucocorticoid receptor: Recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptors
    • Cidlowski, J. A., D. L. Bellingham, F. E. Powell-Oliver, D. B. Lubahn, and M. Sar. 1990. Novel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vitro and distinct localization of cytoplasmic and nuclear receptors. Mol. Endocrinol. 4:1427-1437.
    • (1990) Mol. Endocrinol , vol.4 , pp. 1427-1437
    • Cidlowski, J.A.1    Bellingham, D.L.2    Powell-Oliver, F.E.3    Lubahn, D.B.4    Sar, M.5
  • 7
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar, R., M. Domrachev, and A. E. Lash. 2002. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 30:207-210.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 8
    • 8344271002 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: Updates
    • Frankfurt, O., and S. T. Rosen. 2004. Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates. Curr. Opin. Oncol. 16:553-563.
    • (2004) Curr. Opin. Oncol , vol.16 , pp. 553-563
    • Frankfurt, O.1    Rosen, S.T.2
  • 9
    • 0023743171 scopus 로고
    • Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
    • Funder, J. W., P. T. Pearce, R. Smith, and A. I. Smith. 1988. Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated. Science 242:583-585.
    • (1988) Science , vol.242 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, R.3    Smith, A.I.4
  • 11
    • 0034116143 scopus 로고    scopus 로고
    • A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen
    • Knutti, D., A. Kaul, and A. Kralli. 2000. A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen. Mol. Cell. Biol. 20:2411-2422.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 2411-2422
    • Knutti, D.1    Kaul, A.2    Kralli, A.3
  • 12
    • 0036132913 scopus 로고    scopus 로고
    • Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors
    • Ko, L., G. R. Cardona, A. Henrion-Caude, and W. W. Chin. 2002. Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors. Mol. Cell. Biol. 22:357-369.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 357-369
    • Ko, L.1    Cardona, G.R.2    Henrion-Caude, A.3    Chin, W.W.4
  • 14
    • 9344227341 scopus 로고    scopus 로고
    • TATA box binding protein induces structure in the recombinant glucocorticoid receptor AFI domain
    • Kumar, R., D. E. Volk, J. Li, J. C. Lee, D. G. Gorenstein, and E. B. Thompson. 2004. TATA box binding protein induces structure in the recombinant glucocorticoid receptor AFI domain. Proc. Natl. Acad. Sci. USA 101:16425-16430.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16425-16430
    • Kumar, R.1    Volk, D.E.2    Li, J.3    Lee, J.C.4    Gorenstein, D.G.5    Thompson, E.B.6
  • 16
    • 14744303696 scopus 로고    scopus 로고
    • Expanding functional diversity of the coactivators
    • Lonard, D. M., and B. W. O'Malley. 2005. Expanding functional diversity of the coactivators. Trends Biochem. Sci. 30:126-132.
    • (2005) Trends Biochem. Sci , vol.30 , pp. 126-132
    • Lonard, D.M.1    O'Malley, B.W.2
  • 17
    • 33745090483 scopus 로고    scopus 로고
    • Glucocorticoid receptor isoforms generate transcription specificity
    • Lu, N. Z., and J. A. Cidlowski. 2006. Glucocorticoid receptor isoforms generate transcription specificity. Trends Cell Biol. 16:301-307.
    • (2006) Trends Cell Biol , vol.16 , pp. 301-307
    • Lu, N.Z.1    Cidlowski, J.A.2
  • 18
    • 20844437424 scopus 로고    scopus 로고
    • Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes
    • Lu, N. Z., and J. A. Cidlowski. 2005. Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes. Mol. Cell 18:331-342.
    • (2005) Mol. Cell , vol.18 , pp. 331-342
    • Lu, N.Z.1    Cidlowski, J.A.2
  • 19
    • 4544237452 scopus 로고    scopus 로고
    • A single amino acid change in the first zinc finger of the DNA binding domain of the glucocorticoid receptor regulates differential promoter selectivity
    • Necela, B. M., and J. A. Cidlowski. 2004. A single amino acid change in the first zinc finger of the DNA binding domain of the glucocorticoid receptor regulates differential promoter selectivity. J. Biol. Chem. 279:39279-39288.
    • (2004) J. Biol. Chem , vol.279 , pp. 39279-39288
    • Necela, B.M.1    Cidlowski, J.A.2
  • 20
    • 0038441557 scopus 로고    scopus 로고
    • Development of a flow cytometric assay to study glucocorticoid receptor-mediated gene activation in living cells
    • Necela, B. M., and J. A. Cidlowski. 2003. Development of a flow cytometric assay to study glucocorticoid receptor-mediated gene activation in living cells. Steroids 68:341-350.
    • (2003) Steroids , vol.68 , pp. 341-350
    • Necela, B.M.1    Cidlowski, J.A.2
  • 21
    • 1642546419 scopus 로고    scopus 로고
    • Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength
    • O'Brien, C. A., D. Jia, L. I. Plotkin, T. Bellido, C. C. Powers, S. A. Stewart, S. C. Manolagas, and R. S. Weinstein. 2004. Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength. Endocrinology 145:1835-1841.
    • (2004) Endocrinology , vol.145 , pp. 1835-1841
    • O'Brien, C.A.1    Jia, D.2    Plotkin, L.I.3    Bellido, T.4    Powers, C.C.5    Stewart, S.A.6    Manolagas, S.C.7    Weinstein, R.S.8
  • 22
    • 0035205516 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid-induced osteoporosis
    • Patschan, D., K. Loddenkemper, and F. Buttgereit. 2001. Molecular mechanisms of glucocorticoid-induced osteoporosis. Bone 29:498-505.
    • (2001) Bone , vol.29 , pp. 498-505
    • Patschan, D.1    Loddenkemper, K.2    Buttgereit, F.3
  • 23
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids - new mechanisms for old drugs
    • Rhen, T., and J. A. Cidlowski. 2005. Antiinflammatory action of glucocorticoids - new mechanisms for old drugs. N. Engl. J. Med. 353:1711-1723.
    • (2005) N. Engl. J. Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 24
    • 0032999340 scopus 로고    scopus 로고
    • Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids
    • Rogatsky, I., A. B. Hittelman, D. Pearce, and M. J. Garabedian. 1999. Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids. Mol. Cell. Biol. 19: 5036-5049.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 5036-5049
    • Rogatsky, I.1    Hittelman, A.B.2    Pearce, D.3    Garabedian, M.J.4
  • 25
    • 0030974158 scopus 로고    scopus 로고
    • Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cell-specific transcriptional regulatory mechanisms
    • Rogatsky, I., J. M. Trowbridge, and M. J. Garabedian. 1997. Glucocorticoid receptor-mediated cell cycle arrest is achieved through distinct cell-specific transcriptional regulatory mechanisms. Mol. Cell. Biol. 17:3181-3193.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 3181-3193
    • Rogatsky, I.1    Trowbridge, J.M.2    Garabedian, M.J.3
  • 27
    • 0028831128 scopus 로고    scopus 로고
    • Scheinman, R. I., A. Gualberto, C. M. Jewell, J. A. Cidlowski, and A. S. Baldwin, Jr.1995. Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors. Mol. Cell. Biol. 15:943-953.
    • Scheinman, R. I., A. Gualberto, C. M. Jewell, J. A. Cidlowski, and A. S. Baldwin, Jr.1995. Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors. Mol. Cell. Biol. 15:943-953.
  • 28
    • 23044465261 scopus 로고    scopus 로고
    • Regulation of the expression of caspase-9 by the transcription factor activator protein-4 in glucocorticoid-induced apoptosis
    • Tsujimoto, K., T. Ono, M. Sato, T. Nishida, T. Oguma, and T. Tadakuma. 2005. Regulation of the expression of caspase-9 by the transcription factor activator protein-4 in glucocorticoid-induced apoptosis. J. Biol. Chem. 280: 27638-27644.
    • (2005) J. Biol. Chem , vol.280 , pp. 27638-27644
    • Tsujimoto, K.1    Ono, T.2    Sato, M.3    Nishida, T.4    Oguma, T.5    Tadakuma, T.6
  • 29
    • 18244397482 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis
    • Tuckermann, J. P., A. Kleiman, K. G. McPherson, and H. M. Reichardt. 2005. Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis. Crit. Rev. Clin. Lab. Sci. 42:71-104.
    • (2005) Crit. Rev. Clin. Lab. Sci , vol.42 , pp. 71-104
    • Tuckermann, J.P.1    Kleiman, A.2    McPherson, K.G.3    Reichardt, H.M.4
  • 30
    • 8844276831 scopus 로고    scopus 로고
    • Identification of novel direct transcriptional targets of glucocorticoid receptor
    • U, M., L. Shen, T. Oshida, J. Miyauchi, M. Yamada, and T. Miyashita. 2004. Identification of novel direct transcriptional targets of glucocorticoid receptor. Leukemia 18:1850-1856.
    • (2004) Leukemia , vol.18 , pp. 1850-1856
    • Shen, U.M.L.1    Oshida, T.2    Miyauchi, J.3    Yamada, M.4    Miyashita, T.5
  • 31
    • 0035900780 scopus 로고    scopus 로고
    • Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids
    • Wallace, A. D., and J. A. Cidlowski. 2001. Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids. J. Biol. Chem. 276:42714-42721.
    • (2001) J. Biol. Chem , vol.276 , pp. 42714-42721
    • Wallace, A.D.1    Cidlowski, J.A.2
  • 32
    • 0035224983 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis
    • Weinstein, R. S. 2001. Glucocorticoid-induced osteoporosis. Rev. Endocr. Metab. Disord. 2:65-73.
    • (2001) Rev. Endocr. Metab. Disord , vol.2 , pp. 65-73
    • Weinstein, R.S.1
  • 34
    • 13444291284 scopus 로고    scopus 로고
    • Regulation of apoptosis in osteoclasts and osteoblastic cells
    • Xing, L., and B. F. Boyce. 2005. Regulation of apoptosis in osteoclasts and osteoblastic cells. Biochem. Biophys. Res. Commun. 328:709-720.
    • (2005) Biochem. Biophys. Res. Commun , vol.328 , pp. 709-720
    • Xing, L.1    Boyce, B.F.2
  • 35
    • 0141818114 scopus 로고    scopus 로고
    • Granzyme A mediates glucocorticoid-induced apoptosis in leukemia cells
    • Yamada, M., A. Hirasawa, S. Shiojima, and G. Tsujimoto. 2003. Granzyme A mediates glucocorticoid-induced apoptosis in leukemia cells. FASEB J. 17:1712-1714.
    • (2003) FASEB J , vol.17 , pp. 1712-1714
    • Yamada, M.1    Hirasawa, A.2    Shiojima, S.3    Tsujimoto, G.4


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