Mutations in the phosphatidylinositol 3-kinase pathway: Role in tumor progression and therapeutic implications in breast cancer

Breast Cancer Research

Volumn 13, Issue 6, 2011, Pages

  Miller, Todd W ^a   Rexer, Brent N ^a   Garrett, Joan T ^a   Arteaga, Carlos L ^a,b  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; 2 (1H INDAZOL 4 YL) 6 (4 METHANESULFONYL 1 PIPERAZINYLMETHYL) 4 MORPHOLINOTHIENO[3,2 D]PYRIMIDINE; 4 DIALLYLAMINOMETHYLENE 1,3,4,7,10,11,12,13,14,15,16,17 DODECAHYDRO 6 HYDROXY 1 METHOXYMETHYL 10,13 DIMETHYL 3,7,17 TRIOXO 2 OXACYCLOPENTA[A]PHENANTHREN 11 YL ACETATE; [1 (4 OXO 8 PHENYL 4H 1 BENZOPYRAN 2 YL)MORPHOLINIO]METHOXYSUCCINYLARGINYLGLYCYLASPARTYLSERINE ACETATE; ANTINEOPLASTIC AGENT; AZD 8005; AZD 8055; BGT 226; BKM 120; BYL 719; CAL 101; CH 5132799; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; EVEROLIMUS; GDC 0032; GDC 0980; GSK 1059615; INK 1117; INK 117; INK 128; MAMMALIAN TARGET OF RAPAMYCIN; OSI 027; PF 4691502; PHOSPHATIDYLINOSITOL 3 KINASE; PKI 587; PROTEIN KINASE B; RIDAFOROLIMUS; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; TEMSIROLIMUS; UNCLASSIFIED DRUG; XL 147; XL 765; ENZYME INHIBITOR; PROGESTERONE RECEPTOR;

BREAST CANCER; CELL CYCLE PROGRESSION; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; MOLECULARLY TARGETED THERAPY; MUTATIONAL ANALYSIS; NONHUMAN; REVIEW; TUMOR GROWTH; ANIMAL; BREAST TUMOR; DISEASE COURSE; DRUG EFFECT; FEMALE; GENETICS; MUTATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DISEASE PROGRESSION; ENZYME INHIBITORS; FEMALE; HUMANS; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; SIGNAL TRANSDUCTION;

EID: 80755127903     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3039     Document Type: Review

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