Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes

Virology

Volumn 332, Issue 1, 2005, Pages 16-19

  Yang, Otto O ^a,b   Lin, Holly ^a   Dagarag, Mirabelle ^a   Ng, Hwee L ^a   Effros, Rita B ^a,b   Uittenbogaart, Christel H ^a,b  

^a UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytotoxic T lymphocytes; Granzyme B; Perforin

Indexed keywords

GRANZYME B; PERFORIN; TELOMERASE;

ARTICLE; CELL AGING; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; LYMPHOCYTE FUNCTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE;

AGING; CELL AGING; CHRONIC DISEASE; GRANZYMES; HIV-1; HUMANS; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; SERINE ENDOPEPTIDASES; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 12344301910     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2004.11.028     Document Type: Article

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