Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization

Nature Immunology

Volumn 1, Issue 4, 2000, Pages 305-310

  Cella, Marina ^a   Facchetti, Fabio ^b   Lanzavecchia, Antonio ^c   Colonna, Marco ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^b UNIVERSITY OF BRESCIA   (Italy)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 LIGAND; VIRUS ANTIGEN;

ANTIGEN PRESENTATION; ARTICLE; DENDRITIC CELL; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INFLUENZA; LYMPHOCYTE ACTIVATION; ORTHOMYXOVIRUS; PLASMA CELL; TH1 CELL; VIROLOGY;

ANTIGEN PRESENTATION; ANTIGENS, VIRAL; CD40 LIGAND; DENDRITIC CELLS; HUMANS; IMMUNE TOLERANCE; INFLUENZA, HUMAN; LYMPHOCYTE ACTIVATION; ORTHOMYXOVIRIDAE; PLASMA CELLS; TH1 CELLS;

EID: 0034304003     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/79747     Document Type: Article

References (48)

1. Steinman, R. M. The dendridc cell system and its role in immunogenicity. Annu. Rev. Immunol. 9, 271-296 (1991).
2. Banehereau, J. & Steinman, R. M. Dendritic cells and the control of immunity. Nature 392, 245-252 (1998).
3. Sauter, B. M. et al. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J. Exp. Med. 191, 423-434 (2000).
4. Cyster, J. G. Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs. J. Exp. Med. 189, 447-450 (1999).
5. Grouard, G., Durand, I., Filgueira, L., Banehereau, J. & Liu, Y. J. Dendritic cells capable of stimulating T cells in germinal centres. Nature 384, 364-367 (1996).
6. Bjorck, P., Flores-Romo, L. & Liu, Y. J. Human interdigitating dendritic cells directly stimulate CD40-activated naive B cells. Eur. J. Immunol. 27, 1266-1274 (1997).
7. O'Doherty, U. et al. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. J. Exp. Med. 178, 1067-1076 (1993).
8. O'Doherty. U. et al. Human blood contains two subsets of dendritic cells, one immunologicatly mature and the other immature. Immunology 82, 487-493 (1994).
9. Grouard, G. et al. The enigmatic ptasmacytoid T cells develop into dendritic cells with interleukin (1L)-3 and CD40-ligand. J. Exp. Med. 185, 1101-1111 (1997).
10. Olweus, J. et al. Dendritic cell ontogeny: a human dendritic cell lineage of myeloid origin. Proc. Natl Acad Sci. USA 94, 12551-12556 (1997).
11. + peripheral blood cells with dendritic precursor characteristics.), Immunol. 161, 740-748 (1998).
12. Cella, M. et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type 1 interferon. Nature Med. 5, 919-923 (1999).
13. Robinson, S. P. et al. Human peripheral blood contains two distinct lineages of dendritic cells. Eur. J. Immunol. 29, 2769-2778 (1999).
14. + subset of human blood dendritic cells is a direct precursor of Langerhans cells. J. Immunol. 163, 1409-1419 (1999).
15. + peripheral blood dendritic cells are differentially regulated by cytokines. J. Immunol. 163, 3250-3259 (1999).
16. Vollenweider, R. & Lennert, K. Plasmacytoid T-cell clusters in non-specific lymphadenitis. Virchows Archiv. (Cell Pathol.) 44, 1-14 (1983).
17. Facchetti, F., De Wolf-Peeters, C, van den Oord, J. J., De vos, R. & Desmet, V. J. Plasmacytoid T cells: a cell population normally present in the reactive lymph node. An immunohistochemical and electron microscopic study. Hum. Pathol. 19, 1085-1092 (1988).
18. Facchetti, F. et al. Plasmacytoid T cells. Immunohistochemical evidence for their monocyte/macrophage origin. Am. J. Pathol. 133, 15-21 (1988).
19. Girard, J. P. & Springer, T. A. High endothelial venules (HEVs): specialized endothelium for lymphocyte migration, Immunol. Today 16, 449-457 (1995).
20. Piali, L. et al. The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig. Eur. J. Immunol. 28, 961-972 (1988).
21. Farber, J. M. Mig and IP-10: CXC chemokines that target lymphocytes. J. Leukoc. Biol. 61, 246-257 (1997).
22. Perussia, B., Fanning, V. & Trinchieri, G. A leukocyte subset bearing HLA-DR antigens is responsible for in vitro alpha interferon production in response to viruses. Nat. Immun. Cell Growth Regul. 4, 120-137 (1985).
23. + cell subsets in human peripheral blood. Immunology 68, 488-490 (1989).
24. Fitzgerald-Bocarsly, P., Feldman, M., Mendelsohn, M., Curl, S. & Lopez, C. Human mononuclear cells which produce interferon-α during NK(HSV-FS) assays are HLA-DR positive cells distinct from cytolytic natural killer effectors. J. Leukoc. Biol. 43, 323-334 (1988).
25. Feldman, M. & Fitzgerald-Bocarsly, P. Sequential enrichment and immunocytochemical visualization of human interferon-α producing cells. J. Interferon Res. 10, 435-446 (1990).
26. Fitzgerald-Bocarsly, P. Human natural interferon-α producing cells. Pharmocol. Ther. 60, 39-62 (1993).
27. Siegal, F. P. et al. The nature of the principal type 1 interferon-producing cells in human blood. Science 284, 1835-1837 (1999).
28. Rissoan, M. C. et al. Reciprocal control of T helper cell and dendritic cell differentiation. Science 283, 1183-1186 (1999).
29. Liu, Y. J. & Blom, B. Introduction: Th2-inducing DC2 for immunotherapy. Blood 95, 2482-2483 (2000).
30. Parronchi, P. et al. Effects of interferon-α on cytokine profile.T cell receptor repertoire and peptide reactivity of human allergen-specific T cells. Eur. J. Immunol. 26, 697-703 (1996).
31. Rogge, L. et al. Selective expression of an interleukin-12 receptor component by human T helper 1 cells. J. Exp. Med. 185, 825-831 (1997).
32. Cella, M. et al. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189, 821-829 (1999).
33. Arpinati, M., Green, C. L., Heimfeld, S., Heuser, J. E. & Anasetti, C. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood 95, 2484-2490 (2000).
34. Trinchieri. G. Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv. Immunol. 70, 83-243 (1998).
35. Gerosa, F. et al. CD4(+) T cell clones producing both interferon-gamma and interleukin-10 predominate in bronchoalveolar lavages of active pulmonary tuberculosis patients. Clin. Immunol. 92, 224-234 (1999).
36. Groux, R. et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389, 737-742 (1997).
37. Gerosa, F. et al. Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-γ and interleukin-10. J. Exp. Med. 183, 2559-2569 (1996).
38. Ridge, J. P., Di Rosa, F. & Matzinger, P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 393, 474-478 (1998).
39. Facchetti, F. et al. Plasmacytoid monocytes (so-called plasmacytoid T cells) in granulomatous lymphadenitis. Hum. Pathol. 20, 588-593 (1989).
40. Facchetti, F., De Wolf-Peters, C., Marocolo, D. & De Vos, R. Plasmacytoid monocytes in granulomatous lymphadenitis and in histiocytic necrotizing lymphadenitis. Sorcoidosis 8, 170-171 (1991).
41. Facchetti, F. et al. Expression of inducible nitric oxide synthase in human granulomas and histiocytic reactions. Am. J. Pathol. 154, 45-52 (1999).
42. H2 and unpolarized T cells. Nature Immunol. 1, 311-316 (2000).
43. Iwasaki, A. & Kelsall, B. L. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 190, 229-239 (1999).
44. Stumbles, P.A et al. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th 1 immunity. J. Exp. Med. 188, 2019-2031 (1998).
45. Khanna, A. et al. Effects of liver-derived dendritic cell progenitors onTh1-andTh2-like cytokine responses in vitro and in vivo. J. Immunol. 164, 1346-1354 (2000).
46. Res, P. C., Couwenberg, F., Vyth-Dreese, F.A. & Spits, H. Expression of pTα mRNA in a committed dendritic cell precursor in the human thymus. Blood 94, 2647-2657 (1999).
47. Steinman, M. R., Turley, S., Melmann, I. & Inaba, K. The induction of tolerance by dendritic cells that have captured apoptotic cells. J. Exp. Med. 191, 411-416 (2000).
48. Sallusto, F., Cella, M., Danieli, C. & Lanzavecchia, A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment; downregulation by cytokines and bacterial products. J. Exp. Med. 182, 389-100 (1995).