-
1
-
-
45849117967
-
Wnt signal transduction pathways
-
Komiya Y, Habas R. Wnt signal transduction pathways. Organogenesis 2008; 4: 68-75. (Pubitemid 351881302)
-
(2008)
Organogenesis
, vol.4
, Issue.2
, pp. 68-75
-
-
Komiya, Y.1
Habas, R.2
-
2
-
-
67449150167
-
A Wnt survival guide: From flies to human disease
-
Chien AJ, Conrad WH, Moon RT. A Wnt survival guide: from flies to human disease. J Invest Dermatol 2009; 129: 1614-1627.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1614-1627
-
-
Chien, A.J.1
Conrad, W.H.2
Moon, R.T.3
-
3
-
-
43049117151
-
The Wnt/frizzled pathway in cardiovascular development and disease: Friend or foe?
-
Van de Schans VA, Smits JF, Blankesteijn WM. The Wnt/frizzled pathway in cardiovascular development and disease: friend or foe? Eur J Pharmacol 2008; 585: 338-345.
-
(2008)
Eur J Pharmacol
, vol.585
, pp. 338-345
-
-
Van De Schans, V.A.1
Smits, J.F.2
Blankesteijn, W.M.3
-
4
-
-
77955155919
-
The multiple phases and faces of Wnt signaling during cardiac differentiation and development
-
Gessert S, Kühl M. The multiple phases and faces of Wnt signaling during cardiac differentiation and development. Circ Res 2010; 107: 186-199.
-
(2010)
Circ Res
, vol.107
, pp. 186-199
-
-
Gessert, S.1
Kühl, M.2
-
5
-
-
77958450885
-
The role of Wnt signaling in physiological and pathological angiogenesis
-
Dejana E. The role of Wnt signaling in physiological and pathological angiogenesis. Circ Res 2010; 107: 943-952.
-
(2010)
Circ Res
, vol.107
, pp. 943-952
-
-
Dejana, E.1
-
6
-
-
53049088426
-
WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny
-
Schmidt-Ott KM, Barasch J. WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny. Kidney Int 2008; 74: 1004-1008.
-
(2008)
Kidney Int
, vol.74
, pp. 1004-1008
-
-
Schmidt-Ott, K.M.1
Barasch, J.2
-
7
-
-
0037309239
-
You Wnt some, you lose some: Oncogenes in the Wnt signaling pathway
-
DOI 10.1016/S0959-437X(02)00012-6
-
Van Es JH, Barker N, Clevers H. You Wnt some, you lose some: oncogenes in the Wnt signaling pathway. Curr Opin Genet Dev 2003; 13: 28-33. (Pubitemid 36143924)
-
(2003)
Current Opinion in Genetics and Development
, vol.13
, Issue.1
, pp. 28-33
-
-
Van Es, J.H.1
Barker, N.2
Clevers, H.3
-
8
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009; 17: 9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
10
-
-
77956918119
-
Multifarious molecular signaling cascades of cardiac hypertrophy: Can the muddy waters be cleared?
-
Balakumar P, Jagadeesh G. Multifarious molecular signaling cascades of cardiac hypertrophy: can the muddy waters be cleared? Pharmacol Res 2010; 62: 365-383.
-
(2010)
Pharmacol Res
, vol.62
, pp. 365-383
-
-
Balakumar, P.1
Jagadeesh, G.2
-
11
-
-
34748812548
-
The Frizzled family of unconventional G-protein-coupled receptors
-
DOI 10.1016/j.tips.2007.09.001, PII S0165614707002088
-
Schulte G, Bryja V. The frizzled family of unconventional G-protein-coupled receptors. Trends Pharmacol Sci 2007; 28: 518-525. (Pubitemid 47488504)
-
(2007)
Trends in Pharmacological Sciences
, vol.28
, Issue.10
, pp. 518-525
-
-
Schulte, G.1
Bryja, V.2
-
12
-
-
33747339465
-
Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
-
Gordon MD, Nusse R. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem 2006; 281: 22429-22433.
-
(2006)
J Biol Chem
, vol.281
, pp. 22429-22433
-
-
Gordon, M.D.1
Nusse, R.2
-
13
-
-
33847019563
-
Multiplicity of the interactions of Wnt proteins and their receptors
-
DOI 10.1016/j.cellsig.2006.11.001, PII S0898656806002956
-
Kikuchi A, Yamamoto H, Kishida S. Multiplicity of the interactions of Wnt proteins and their receptors. Cell Signal 2007; 19: 659-671. (Pubitemid 46275377)
-
(2007)
Cellular Signalling
, vol.19
, Issue.4
, pp. 659-671
-
-
Kikuchi, A.1
Yamamoto, H.2
Kishida, S.3
-
15
-
-
0037439138
-
Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
-
DOI 10.1101/gad.1022203
-
Habas R, Dawid IB, Xi He. Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev 2003; 17: 295-309. (Pubitemid 36105900)
-
(2003)
Genes and Development
, vol.17
, Issue.2
, pp. 295-309
-
-
Habas, R.1
Dawid, I.B.2
He, X.3
-
16
-
-
27144449757
-
Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism
-
Povelones M, Howes R, Fish M, Nusse R. Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism. Genetics 2005; 171: 1643-1654.
-
(2005)
Genetics
, vol.171
, pp. 1643-1654
-
-
Povelones, M.1
Howes, R.2
Fish, M.3
Nusse, R.4
-
17
-
-
0031456672
-
Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
-
DOI 10.1038/37138
-
Slusarski DC, Corces VG, Moon RT. Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 1997; 390: 410-413. (Pubitemid 28027323)
-
(1997)
Nature
, vol.390
, Issue.6658
, pp. 410-413
-
-
Slusarski, D.C.1
Corces, V.G.2
Moon, R.T.3
-
18
-
-
33644635213
-
Beta-catenin, cancer, and G proteins: Not just for frizzleds anymore
-
Malbon CC. Beta-catenin, cancer, and G proteins: not just for frizzleds anymore. Sci STKE 2005; 2005: pe35.
-
(2005)
Sci STKE 2005
-
-
Malbon, C.C.1
-
19
-
-
33846474121
-
G-protein-coupled receptors and cancer
-
DOI 10.1038/nrc2069, PII NRC2069
-
Dorsam RT, Gutkind JS. G-protein-coupled receptors and cancer. Nat Rev Cancer 2007; 7: 79-94. (Pubitemid 46164746)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.2
, pp. 79-94
-
-
Dorsam, R.T.1
Gutkind, J.S.2
-
20
-
-
33845802651
-
Noncanonical Wnt Signaling through G Protein-Linked PKCδ Activation Promotes Bone Formation
-
DOI 10.1016/j.devcel.2006.11.003, PII S1534580706005089
-
Tu X, Joeng KS, Nakayama KI, Nakayama K, Rajagopal J, Carroll TJ, McMahon AP, Long F. Noncanonical Wnt signaling through G protein-linked PKCd activation promotes bone formation. Dev Cell 2007; 12: 113-127. (Pubitemid 46002598)
-
(2007)
Developmental Cell
, vol.12
, Issue.1
, pp. 113-127
-
-
Tu, X.1
Joeng, K.S.2
Nakayama, K.I.3
Nakayama, K.4
Rajagopal, J.5
Carroll, ThomasJ.6
McMahon, A.P.7
Long, F.8
-
21
-
-
77953814474
-
G beta gamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity
-
Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E. G beta gamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Sci Signal 2010; 3: ra37.
-
(2010)
Sci Signal
, vol.3
-
-
Jernigan, K.K.1
Cselenyi, C.S.2
Thorne, C.A.3
Hanson, A.J.4
Tahinci, E.5
Hajicek, N.6
Oldham, W.M.7
Lee, L.A.8
Hamm, H.E.9
Hepler, J.R.10
Kozasa, T.11
Linder, M.E.12
Lee, E.13
-
22
-
-
0037229938
-
Runnin' with the Dvl: Proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
-
DOI 10.1006/dbio.2002.0869
-
Wharton Jr KA. Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction. Dev Biol 2003; 253: 1-17. (Pubitemid 36068000)
-
(2003)
Developmental Biology
, vol.253
, Issue.1
, pp. 1-17
-
-
Wharton Jr., K.A.1
-
23
-
-
67649470380
-
Proximal events in Wnt signal transduction
-
Angers S, Moon RT. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 2009; 10: 468-477.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 468-477
-
-
Angers, S.1
Moon, R.T.2
-
25
-
-
0036266596
-
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
-
DOI 10.1172/JCI200214276
-
Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer J-D. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002; 109: 1417-1427. (Pubitemid 34596167)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.11
, pp. 1417-1427
-
-
Nguyen, G.1
Delarue, F.2
Burckle, C.3
Bouzhir, L.4
Giller, T.5
Sraer, J.-D.6
-
26
-
-
78649362445
-
Cardiovascular and renal pathological implications of prorenin, renin and the prorenin receptor: Promising young players from the old renin angiotensin aldosterone system
-
Balakumar P, Jagadeesh G. Cardiovascular and renal pathological implications of prorenin, renin and the prorenin receptor: Promising young players from the old renin angiotensin aldosterone system. J Cardiovasc Pharmacol 2010; 56: 570-579.
-
(2010)
J Cardiovasc Pharmacol
, vol.56
, pp. 570-579
-
-
Balakumar, P.1
Jagadeesh, G.2
-
27
-
-
75149152420
-
The biology of the prorenin receptor
-
Nguyen G, Muller DN. The biology of the prorenin receptor. J Am Soc Nephrol 2010; 21: 18-23.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 18-23
-
-
Nguyen, G.1
Muller, D.N.2
-
28
-
-
75649120756
-
Requirement of prorenin receptor and vacuolar H+-ATPasemediated acidification for Wnt signaling
-
Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, Ingelfinger D, Boutros M, Niehrs C. Requirement of prorenin receptor and vacuolar H+-ATPasemediated acidification for Wnt signaling. Science 2010; 327: 459-463.
-
(2010)
Science
, vol.327
, pp. 459-463
-
-
Cruciat, C.M.1
Ohkawara, B.2
Acebron, S.P.3
Karaulanov, E.4
Reinhard, C.5
Ingelfinger, D.6
Boutros, M.7
Niehrs, C.8
-
29
-
-
77956635784
-
Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor
-
Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol 2010; 20: 1263-1268.
-
(2010)
Curr Biol
, vol.20
, pp. 1263-1268
-
-
Buechling, T.1
Bartscherer, K.2
Ohkawara, B.3
Chaudhary, V.4
Spirohn, K.5
Niehrs, C.6
Boutros, M.7
-
30
-
-
77956635633
-
Regulation of Frizzleddependent planar polarity signaling by a V-ATPase subunit
-
Hermle T, Saltukoglu D, Grünewald J, Walz G, Simons M. Regulation of Frizzleddependent planar polarity signaling by a V-ATPase subunit. Curr Biol 2010; 20: 1269-1276.
-
(2010)
Curr Biol
, vol.20
, pp. 1269-1276
-
-
Hermle, T.1
Saltukoglu, D.2
Grünewald, J.3
Walz, G.4
Simons, M.5
-
31
-
-
79551560598
-
Renin and prorenin receptor in hypertension: What's new?
-
Nguyen G. Renin and prorenin receptor in hypertension: what's new? Curr Hypertens Rep 2011; 13: 79-85.
-
(2011)
Curr Hypertens Rep
, vol.13
, pp. 79-85
-
-
Nguyen, G.1
-
32
-
-
0032967755
-
Dishevelled: At the crossroads of divergent intracellular signaling pathways
-
DOI 10.1016/S0925-4773(99)00046-5, PII S0925477399000465
-
Boutros M, Mlodzik M. Dishevelled: at the crossroads of divergent intracellular signaling pathways. Mech Dev 1999; 83: 27-37. (Pubitemid 29302079)
-
(1999)
Mechanisms of Development
, vol.83
, Issue.1-2
, pp. 27-37
-
-
Boutros, M.1
Mlodzik, M.2
-
33
-
-
0035989413
-
A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin
-
Penton A, Wodarz A, Nusse R. A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin. Genetics 2002; 161: 747-762. (Pubitemid 34705414)
-
(2002)
Genetics
, vol.161
, Issue.2
, pp. 747-762
-
-
Penton, A.1
Wodarz, A.2
Nusse, R.3
-
34
-
-
0029683606
-
The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
-
Yost C, Torres M, Miller JR, Huang E, Kimelman D, Moon RT. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev 1996; 10: 1443-1454. (Pubitemid 26260702)
-
(1996)
Genes and Development
, vol.10
, Issue.12
, pp. 1443-1454
-
-
Yost, C.1
Torres, M.2
Miller, J.R.3
Huang, E.4
Kimelman, D.5
Moon, R.T.6
-
35
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way
-
DOI 10.1242/dev.01117
-
He X, Semenov M, Tamai K, Zeng X. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 2004; 131: 1663-1677. (Pubitemid 38559836)
-
(2004)
Development
, vol.131
, Issue.8
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
36
-
-
38949194936
-
Initiation of Wnt signaling: Control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
-
DOI 10.1242/dev.013540
-
Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development 2008; 135: 367-375. (Pubitemid 351228428)
-
(2008)
Development
, vol.135
, Issue.2
, pp. 367-375
-
-
Zeng, X.1
Huang, H.2
Tamai, K.3
Zhang, X.4
Harada, Y.5
Yokota, C.6
Almeida, K.7
Wang, J.8
Doble, B.9
Woodgett, J.10
Wynshaw-Boris, A.11
Hsieh, J.-C.12
He, X.13
-
37
-
-
58149185151
-
Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling
-
Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Lee SJ, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC. Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling. PLoS One 2008; 3: e4046.
-
(2008)
PLoS One
, vol.3
-
-
Piao, S.1
Lee, S.H.2
Kim, H.3
Yum, S.4
Stamos, J.L.5
Xu, Y.6
Lee, S.J.7
Lee, J.8
Oh, S.9
Han, J.K.10
Park, B.J.11
Weis, W.I.12
Ha, N.C.13
-
38
-
-
20944435474
-
Wnt signaling: Multiple functions in neural development
-
DOI 10.1007/s00018-005-4552-2
-
Ille F, Sommer L. Wnt signaling: multiple functions in neural development. Cell Mol Life Sci 2005; 62: 1100-1108. (Pubitemid 40868528)
-
(2005)
Cellular and Molecular Life Sciences
, vol.62
, Issue.10
, pp. 1100-1108
-
-
Ille, F.1
Sommer, L.2
-
39
-
-
0032916351
-
WNT targets: Repression and activation
-
DOI 10.1016/S0168-9525(98)01634-5, PII S0168952598016345
-
Nusse R. WNT targets: repression and activation. Trends Genet 1999; 15: 1-3. (Pubitemid 29207333)
-
(1999)
Trends in Genetics
, vol.15
, Issue.1
, pp. 1-3
-
-
Nusse, R.1
-
40
-
-
33845355511
-
Diversity of LEF/TCF action in development and disease
-
DOI 10.1038/sj.onc.1210056, PII 1210056
-
Arce L, Yokoyama NN, Waterman ML. Diversity of LEF/TCF action in development and disease. Oncogene 2006; 25: 7492-7504. (Pubitemid 44885748)
-
(2006)
Oncogene
, vol.25
, Issue.57
, pp. 7492-7504
-
-
Arce, L.1
Yokoyama, N.N.2
Waterman, M.L.3
-
41
-
-
77954210220
-
An updated overview on Wnt signaling pathways: A prelude for more
-
Rao TP, Kü hl M. An updated overview on Wnt signaling pathways: a prelude for more. Circ Res 2010; 106: 1798-1806.
-
(2010)
Circ Res
, vol.106
, pp. 1798-1806
-
-
Rao, T.P.1
Kühl, M.2
-
42
-
-
0036837672
-
Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin mediated cardiac hypertrophic growth
-
Wilkins BJ, De Windt LJ, Bueno OF, Braz JC, Glascock BJ, Kimball TF, Molkentin JD. Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin mediated cardiac hypertrophic growth. Mol Cell Biol 2002; 22: 7603-7613.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7603-7613
-
-
Wilkins, B.J.1
De Windt, L.J.2
Bueno, O.F.3
Braz, J.C.4
Glascock, B.J.5
Kimball, T.F.6
Molkentin, J.D.7
-
43
-
-
55849135237
-
Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation
-
Kerkela R, Kockeritz L, Macaulay K, Zhou J, Doble BW, Beahm C, Greytak S, Woulfe K, Trivedi CM, Woodgett JR, Epstein JA, Force T, Huggins GS. Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation. J Clin Invest 2008; 118: 3609-3618.
-
(2008)
J Clin Invest
, vol.118
, pp. 3609-3618
-
-
Kerkela, R.1
Kockeritz, L.2
MacAulay, K.3
Zhou, J.4
Doble, B.W.5
Beahm, C.6
Greytak, S.7
Woulfe, K.8
Trivedi, C.M.9
Woodgett, J.R.10
Epstein, J.A.11
Force, T.12
Huggins, G.S.13
-
44
-
-
0037169557
-
2
-
DOI 10.1074/jbc.M109440200
-
Fujino H, West KA, Regan JW. Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. J Biol Chem 2002; 277: 2614-2619. (Pubitemid 34953286)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.4
, pp. 2614-2619
-
-
Fujino, H.1
West, K.A.2
Regan, J.W.3
-
45
-
-
17844382139
-
G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the β-catenin pathway
-
DOI 10.1073/pnas.0501535102
-
Yang M, Zhong WW, Srivastava N, Slavin A, Yang J, Hoey T, An S. G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the b-catenin pathway. Proc Natl Acad Sci USA 2005; 102: 6027-6032. (Pubitemid 40594249)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.17
, pp. 6027-6032
-
-
Yang, M.1
Zhong, W.W.2
Srivastava, N.3
Slavin, A.4
Yang, J.5
Hoey, T.6
An, S.7
-
46
-
-
36849056116
-
Nuclear stabilization of β-catenin and inactivation of glycogen synthase kinase-3β by gonadotropin-releasing hormone: Targeting Wnt signaling in the pituitary gonadotrope
-
DOI 10.1210/me.2007-0268
-
Gardner S, Maudsley S, Millar RP, Pawson AJ. Nuclear stabilization of beta-catenin and inactivation of glycogen synthase kinase-3beta by gonadotropin-releasing hormone: targeting Wnt signaling in the pituitary gonadotrope. Mol Endocrinol 2007; 21: 3028-3038. (Pubitemid 350223512)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.12
, pp. 3028-3038
-
-
Gardner, S.1
Maudsley, S.2
Millar, R.P.3
Pawson, A.J.4
-
47
-
-
55749091843
-
Parathyroid hormone signaling through low-density lipoprotein-related protein 6
-
Wan M, Yang C, Li J, Wu X, Yuan H, Ma H, He X, Nie S, Chang C, Cao X. Parathyroid hormone signaling through low-density lipoprotein-related protein 6. Genes Dev 2008; 22: 2968-2979.
-
(2008)
Genes Dev
, vol.22
, pp. 2968-2979
-
-
Wan, M.1
Yang, C.2
Li, J.3
Wu, X.4
Yuan, H.5
Ma, H.6
He, X.7
Nie, S.8
Chang, C.9
Cao, X.10
-
48
-
-
69049083343
-
Rho GTPase activity modulates Wnt3a/beta-catenin signaling
-
Rossol-Allison J, Stemmle LN, Swenson-Fields KI, Kelly P, Fields PE, McCall SJ, Casey PJ, Fields TA. Rho GTPase activity modulates Wnt3a/beta-catenin signaling. Cell Signal 2009; 21: 1559-1568.
-
(2009)
Cell Signal
, vol.21
, pp. 1559-1568
-
-
Rossol-Allison, J.1
Stemmle, L.N.2
Swenson-Fields, K.I.3
Kelly, P.4
Fields, P.E.5
McCall, S.J.6
Casey, P.J.7
Fields, T.A.8
-
49
-
-
0035954281
-
Head inducer dickkopf-1 is a ligand for Wnt coreceptor LRP6
-
DOI 10.1016/S0960-9822(01)00290-1
-
Semenov MV, Tamai K, Brott BK, Kuhl M, Sokol S, He X. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol 2001; 11: 951-961. (Pubitemid 32589186)
-
(2001)
Current Biology
, vol.11
, Issue.12
, pp. 951-961
-
-
Semenov, M.V.1
Tamai, K.2
Brott, B.K.3
Kuhl, M.4
Sokol, S.5
He, X.6
-
50
-
-
33845359084
-
Function and biological roles of the Dickkopf family of Wnt modulators
-
DOI 10.1038/sj.onc.1210054, PII 1210054
-
Niehrs C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 2006; 25: 7469-7481. (Pubitemid 44885746)
-
(2006)
Oncogene
, vol.25
, Issue.57
, pp. 7469-7481
-
-
Niehrs, C.1
-
51
-
-
0142136734
-
The Wnt/β-catenin pathway regulates cardiac valve formation
-
DOI 10.1038/nature02028
-
Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature 2003; 425: 633-637. (Pubitemid 37280148)
-
(2003)
Nature
, vol.425
, Issue.6958
, pp. 633-637
-
-
Hurlstone, A.F.L.1
Haramis, A.-P.G.2
Wienholds, E.3
Begthel, H.4
Korving, J.5
Van Eeden, F.6
Cuppen, E.7
Zivkovic, D.8
Plasterk, R.H.A.9
Clevers, H.10
-
52
-
-
79960614123
-
Current and emerging therapies for the treatment of osteoporosis
-
Waalen J. Current and emerging therapies for the treatment of osteoporosis. J Expt Pharmacol 2010; 2: 121-134.
-
(2010)
J Expt Pharmacol
, vol.2
, pp. 121-134
-
-
Waalen, J.1
-
53
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
DOI 10.1242/jcs.00623
-
Kawano Y, Kypta R. Secreted antagonists of the Wnt signalling pathway. J Cell Sci 2003; 116: 2627-2634. (Pubitemid 36857216)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.13
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
55
-
-
77951915105
-
The Hippo pathway regulates Wnt/beta-catenin signaling
-
Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L. The Hippo pathway regulates Wnt/beta-catenin signaling. Dev Cell 2010; 18: 579-591.
-
(2010)
Dev Cell
, vol.18
, pp. 579-591
-
-
Varelas, X.1
Miller, B.W.2
Sopko, R.3
Song, S.4
Gregorieff, A.5
Fellouse, F.A.6
Sakuma, R.7
Pawson, T.8
Hunziker, W.9
McNeill, H.10
Wrana, J.L.11
Attisano, L.12
-
56
-
-
0037043688
-
Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis
-
Pandur P, Lasche M, Eisenberg LM, Kuhl M. Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature 2002; 418: 636-641.
-
(2002)
Nature
, vol.418
, pp. 636-641
-
-
Pandur, P.1
Lasche, M.2
Eisenberg, L.M.3
Kuhl, M.4
-
57
-
-
33847217907
-
Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta-catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek
-
Canapero L, Huang YL, Staudt N, Masasumi T, Ahrendt R, Kazanskaya O, Niehrs C, Houart C. Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta-catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes Dev 2007; 21: 465-480.
-
(2007)
Genes Dev
, vol.21
, pp. 465-480
-
-
Canapero, L.1
Huang, Y.L.2
Staudt, N.3
Masasumi, T.4
Ahrendt, R.5
Kazanskaya, O.6
Niehrs, C.7
Houart, C.8
-
58
-
-
2642582621
-
Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway
-
DOI 10.1074/jbc.M311724200
-
Maye P, Zheng J, Li L, Wu D. Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway. J Biol Chem 2004; 279: 24659-24665. (Pubitemid 38725333)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.23
, pp. 24659-24665
-
-
Maye, P.1
Zheng, J.2
Li, L.3
Wu, D.4
-
59
-
-
0041695485
-
A second canon: Functions and mechanisms of β-catenin-independent Wnt signaling
-
DOI 10.1016/S1534-5807(03)00266-1, PII S1534580703002661
-
Veeman MT, Axelrod JD, Moon RT. A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell 2003; 5: 367-377. (Pubitemid 37107667)
-
(2003)
Developmental Cell
, vol.5
, Issue.3
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
60
-
-
0344413477
-
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
-
DOI 10.1016/S1097-2765(03)00427-1
-
Wong HC, Bourdelas A, Krauss A, Lee HJ, Shao Y, Wu D, Mlodzik M, Shi DL, Zheng J. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol Cell 2003; 12: 1251-1260. (Pubitemid 37487932)
-
(2003)
Molecular Cell
, vol.12
, Issue.5
, pp. 1251-1260
-
-
Wong, H.-C.1
Bourdelas, A.2
Krauss, A.3
Lee, H.-J.4
Shao, Y.5
Wu, D.6
Mlodzik, M.7
Shi, D.-L.8
Zheng, J.9
-
61
-
-
61849116777
-
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization
-
Simons M, Gault WJ, Gotthardt D, Rohatgi R, Klein TJ, Shao Y, Lee HJ, Wu AL, Fang Y, Satlin LM, Dow JT, Chen J, Zheng J, Boutros M, Mlodzik M. Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization. Nat Cell Biol 2009; 11: 286-294.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 286-294
-
-
Simons, M.1
Gault, W.J.2
Gotthardt, D.3
Rohatgi, R.4
Klein, T.J.5
Shao, Y.6
Lee, H.J.7
Wu, A.L.8
Fang, Y.9
Satlin, L.M.10
Dow, J.T.11
Chen, J.12
Zheng, J.13
Boutros, M.14
Mlodzik, M.15
-
62
-
-
27744535862
-
The developmental biology of Dishevelled: An enigmatic protein governing cell fate and cell polarity
-
DOI 10.1242/dev.02068
-
Wallingford JB, Habas R. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development 2005; 132: 4421-4436. (Pubitemid 41632222)
-
(2005)
Development
, vol.132
, Issue.20
, pp. 4421-4436
-
-
Wallingford, J.B.1
Habas, R.2
-
63
-
-
0035966322
-
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel formin homology protein Daam1
-
DOI 10.1016/S0092-8674(01)00614-6
-
Habas R, Kato Y, He X. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 2001; 107: 843-854. (Pubitemid 34084976)
-
(2001)
Cell
, vol.107
, Issue.7
, pp. 843-854
-
-
Habas, R.1
Kato, Y.2
He, X.3
-
64
-
-
39449101237
-
WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation
-
DOI 10.1038/emboj.2008.9, PII EMBOJ20089
-
Tanegashima K, Zhao H, Dawid IB. WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation. EMBO J 2008; 27: 606-617. (Pubitemid 351273131)
-
(2008)
EMBO Journal
, vol.27
, Issue.4
, pp. 606-617
-
-
Tanegashima, K.1
Zhao, H.2
Dawid, I.B.3
-
65
-
-
38349117987
-
Mechanism of activation of the Formin protein Daam1
-
Liu W, Sato A, Khadka D, Bharti R, Diaz H, Runnels LW, Habas R. Mechanism of activation of the Formin protein Daam1. Proc Natl Acad Sci USA 2008; 105: 210-215.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 210-215
-
-
Liu, W.1
Sato, A.2
Khadka, D.3
Bharti, R.4
Diaz, H.5
Runnels, L.W.6
Habas, R.7
-
66
-
-
0032898364
-
Dishevelled proteins lead to two signaling pathways: Regulation of LEF- 1 and c-Jun N-terminal kinase in mammalian cells
-
DOI 10.1074/jbc.274.1.129
-
Li L, Yuan H, Xie W, Mao J, Caruso AM, McMahon A, Sussman DJ, Wu D. Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. J Biol Chem 1999; 274: 129-134. (Pubitemid 29035039)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.1
, pp. 129-134
-
-
Li, L.1
Yuan, H.2
Xie, W.3
Mao, J.4
Caruso, A.M.5
McMahon, A.6
Sussman, D.J.7
Wu, D.8
-
67
-
-
16644381829
-
Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development
-
DOI 10.1038/nn1374
-
Rosso SB, Sussman D, Wynshaw-Boris A, Salinas PC. Wnt signaling through dishevelled, Rac and JNK regulates dendritic development. Nat Neurosci 2005; 8: 34-42. (Pubitemid 41236729)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.1
, pp. 34-42
-
-
Rosso, S.B.1
Sussman, D.2
Wynshaw-Boris, A.3
Salinas, P.C.4
-
68
-
-
24644499046
-
Wnt and calcium signaling: β-Catenin-independent pathways
-
DOI 10.1016/j.ceca.2005.06.022, PII S0143416005001090
-
Kohn AD, Moon RT. Wnt and calcium signaling: beta-catenin-independent pathways. Cell Calcium 2005; 38: 439-446. (Pubitemid 41283282)
-
(2005)
Cell Calcium
, vol.38
, Issue.SPEC. ISS. 3-4
, pp. 439-446
-
-
Kohn, A.D.1
Moon, R.T.2
-
69
-
-
34250000004
-
Calcium signaling in vertebrate embryonic patterning and morphogenesis
-
DOI 10.1016/j.ydbio.2007.04.043, PII S0012160607008664
-
Slusarski DC, Pelegri F. Calcium signaling in vertebrate embryonic patterning and morphogenesis. Dev Biol 2007; 307: 1-13. (Pubitemid 46890853)
-
(2007)
Developmental Biology
, vol.307
, Issue.1
, pp. 1-13
-
-
Slusarski, D.C.1
Pelegri, F.2
-
70
-
-
0343293801
-
2+/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus
-
DOI 10.1074/jbc.275.17.12701
-
Kuhl M, Sheldahl LC, Malbon CC, Moon RT. Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and frizzled homologs and promotes ventral cell fates in Xenopus. J Biol Chem 2000; 275: 12701-12711. (Pubitemid 30241421)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.17
, pp. 12701-12711
-
-
Kuhl, M.1
Sheldahl, L.C.2
Malbon, C.C.3
Moon, R.T.4
-
71
-
-
0038360821
-
2+ flux, PKC, and CamKII in vertebrate embryos
-
DOI 10.1083/jcb.200211094
-
Sheldahl LC, Slusarski DC, Pandur P, Miller JR, Kuhl M, Moon RT. Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos. J Cell Biol 2003; 161: 769-777. (Pubitemid 36648760)
-
(2003)
Journal of Cell Biology
, vol.161
, Issue.4
, pp. 769-777
-
-
Sheldahl, L.C.1
Slusarski, D.C.2
Pandur, P.3
Miller, J.R.4
Kuhl, M.5
Moon, R.T.6
-
72
-
-
33947319817
-
Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation
-
DOI 10.1152/ajpcell.00590.2005
-
Nilsson LM, Sun ZW, Nilsson J, Nordström I, Chen YW, Molkentin JD, Wide-Swensson D, Hellstrand P, Lydrup ML, Gomez MF. Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation. Am J Physiol Cell Physiol 2007; 292: C1167-C1178. (Pubitemid 46440403)
-
(2007)
American Journal of Physiology - Cell Physiology
, vol.292
, Issue.3
-
-
Nilsson, L.M.1
Sun, Z.-W.2
Nilsson, J.3
Nordstrom, I.4
Chen, Y.-W.5
Molkentin, J.D.6
Wide-Swensson, D.7
Hellstrand, P.8
Lydrup, M.-L.9
Gomez, M.F.10
-
73
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
DOI 10.1038/nrm1983, PII NRM1983
-
Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006; 7: 589-600. (Pubitemid 44325350)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.8
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
74
-
-
33751295132
-
Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion
-
DOI 10.1158/0008-5472.CAN-06-2359
-
Kurayoshi M, Oue N, Yamamoto H, Kishida M, Inoue A, Asahara T, Yasui W, Kikuchi A. Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. Cancer Res 2006; 66: 10439-10448. (Pubitemid 44799765)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10439-10448
-
-
Kurayoshi, M.1
Oue, N.2
Yamamoto, H.3
Kishida, M.4
Inoue, A.5
Asahara, T.6
Yasui, W.7
Kikuchi, A.8
-
75
-
-
36249004436
-
Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration
-
DOI 10.1016/j.bbrc.2007.10.166, PII S0006291X07023467
-
Cheng C, Yeh J, Fan T-P, Smith SK, Charnock-Jones DS. Wnt5a-mediated noncanonical Wnt signalling regulates human endothelial cell proliferation and migration. Biochem Biophys Res Commun 2008; 365: 285-290. (Pubitemid 350137286)
-
(2008)
Biochemical and Biophysical Research Communications
, vol.365
, Issue.2
, pp. 285-290
-
-
Cheng, C.-w.1
Yeh, J.-c.2
Fan, T.-P.3
Smith, S.K.4
Charnock-Jones, D.S.5
-
76
-
-
58049202120
-
Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis
-
Kwon C, Cordes KR, Srivastava D. Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. Cell Cycle 2008; 7: 3815-3818.
-
(2008)
Cell Cycle
, vol.7
, pp. 3815-3818
-
-
Kwon, C.1
Cordes, K.R.2
Srivastava, D.3
-
77
-
-
33847023085
-
Interruption of Wnt signaling attenuates the onset of pressure overload-induced cardiac hypertrophy
-
Van de Schans VA, Van den Borne SW, Strzelecka AE, Janssen BJ, Van der Velden JL, Langen RC, Wynshaw-Boris A, Smits JF, Blankesteijn WM. Interruption of Wnt signaling attenuates the onset of pressure overload-induced cardiac hypertrophy. Hypertension 2007; 49: 473-480.
-
(2007)
Hypertension
, vol.49
, pp. 473-480
-
-
Van De Schans, V.A.1
Van Den Borne, S.W.2
Strzelecka, A.E.3
Janssen, B.J.4
Van Der Velden, J.L.5
Langen, R.C.6
Wynshaw-Boris, A.7
Smits, J.F.8
Blankesteijn, W.M.9
-
78
-
-
78549292104
-
WNT signaling in adult cardiac hypertrophy and remodeling: Lessons learned from cardiac development
-
Bergmann MW. WNT signaling in adult cardiac hypertrophy and remodeling: lessons learned from cardiac development. Circ Res 2010; 107: 1198-1208.
-
(2010)
Circ Res
, vol.107
, pp. 1198-1208
-
-
Bergmann, M.W.1
-
79
-
-
34248363982
-
β-catenin downregulation is required for adaptive cardiac remodeling
-
DOI 10.1161/01.RES.0000266605.63681.5a
-
Baurand A, Zelarayan L, Betney R, Gehrke C, Dunger S, Noack C, Busjahn A, Huelsken J, Taketo MM, Birchmeier W, Dietz R, Bergmann MW. Betacatenin downregulation is required for adaptive cardiac remodeling. Circ Res 2007; 100: 1353-1362. (Pubitemid 46742926)
-
(2007)
Circulation Research
, vol.100
, Issue.9
, pp. 1353-1362
-
-
Baurand, A.1
Zelarayan, L.2
Betney, R.3
Gehrke, C.4
Dunger, S.5
Noack, C.6
Busjahn, A.7
Huelsken, J.8
Taketo, M.M.9
Birchmeier, W.10
Dietz, R.11
Bergmann, M.W.12
-
80
-
-
58149384424
-
Beta-catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation
-
Zelarayán LC, Noack C, Sekkali B, Kmecova J, Gehrke C, Renger A, Zafiriou MP, Van der Nagel R, Dietz R, de Windt LJ, Balligand JL, Bergmann MW. Beta-catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation. Proc Natl Acad Sci USA 2008; 105: 19762-19767.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19762-19767
-
-
Zelarayán, L.C.1
Noack, C.2
Sekkali, B.3
Kmecova, J.4
Gehrke, C.5
Renger, A.6
Zafiriou, M.P.7
Van Der Nagel, R.8
Dietz, R.9
De Windt, L.J.10
Balligand, J.L.11
Bergmann, M.W.12
-
81
-
-
77952296505
-
Association between wnt signal pathway and post-infarction cardiac remodeling/rupture in aged mice
-
Huang Y, Ma YT, Yang YN, Liu F, Chen BD, Li XM. Association between wnt signal pathway and post-infarction cardiac remodeling/rupture in aged mice. Zhonghua Xin Xue Guan Bing Za Zhi. 2009; 37: 826-831.
-
(2009)
Zhonghua Xin Xue Guan Bing Za Zhi.
, vol.37
, pp. 826-831
-
-
Huang, Y.1
Ma, Y.T.2
Yang, Y.N.3
Liu, F.4
Chen, B.D.5
Li, X.M.6
-
82
-
-
70350125871
-
Beta catenin/TCF/LEF1 can directly regulate phenylephrine-induced cell hypertrophy and Anf transcription in cardiomyocytes
-
Zhang CG, Jia ZQ, Li BH, Zhang H, Liu YN, Chen P, Ma KT, Zhou CY. Beta catenin/TCF/LEF1 can directly regulate phenylephrine-induced cell hypertrophy and Anf transcription in cardiomyocytes. Biochem Biophys Res Commun 2009; 390: 258-262.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 258-262
-
-
Zhang, C.G.1
Jia, Z.Q.2
Li, B.H.3
Zhang, H.4
Liu, Y.N.5
Chen, P.6
Ma, K.T.7
Zhou, C.Y.8
-
83
-
-
77950470199
-
Wnt signaling is critical for maladaptive cardiac hypertrophy and accelerates myocardial remodeling
-
Malekar P, Hagenmueller M, Anyanwu A, Buss S, Streit MR, Weiss CS, Wolf D, Riffel J, Bauer A, Katus HA, Hardt SE. Wnt signaling is critical for maladaptive cardiac hypertrophy and accelerates myocardial remodeling. Hypertension 2010; 55: 939-945.
-
(2010)
Hypertension
, vol.55
, pp. 939-945
-
-
Malekar, P.1
Hagenmueller, M.2
Anyanwu, A.3
Buss, S.4
Streit, M.R.5
Weiss, C.S.6
Wolf, D.7
Riffel, J.8
Bauer, A.9
Katus, H.A.10
Hardt, S.E.11
-
84
-
-
0034993731
-
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension
-
DOI 10.1016/S0895-7061(00)01317-0, PII S0895706100013170
-
Laragh J. Laragh's lessons in pathophysiology and clinical pearls for treating hypertension. Am J Hypertens 2001; 14: 186-194. (Pubitemid 32171573)
-
(2001)
American Journal of Hypertension
, vol.14
, Issue.2
, pp. 186-194
-
-
Laragh, J.1
-
85
-
-
25444454353
-
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats
-
DOI 10.1161/01.HYP.0000179573.91016.3f
-
Pilz B, Shagdarsuren E, Wellner M, Fiebeler A, Dechend R, Gratze P, Meiners S, Feldman DL, Webb RL, Garrelds IM, Jan Danser AH, Luft FC, Mü ller DN. Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension 2005; 46: 569-576. (Pubitemid 41376839)
-
(2005)
Hypertension
, vol.46
, Issue.3
, pp. 569-576
-
-
Pilz, B.1
Shagdarsuren, E.2
Wellner, M.3
Fiebeler, A.4
Dechend, R.5
Gratze, P.6
Meiners, S.7
Feldman, D.L.8
Webb, R.L.9
Garrelds, I.M.10
Danser, A.H.J.11
Luft, F.C.12
Muller, D.N.13
-
86
-
-
33646160993
-
Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
-
DOI 10.1161/01.HYP.0000215838.48170.0b, PII 0000426820060500000019
-
Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, Nishiyama A, Inagami T, Hayashi M. Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 2006; 47: 894-900. (Pubitemid 44297561)
-
(2006)
Hypertension
, vol.47
, Issue.5
, pp. 894-900
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
Nakagawa, T.6
Nishiyama, A.7
Inagami, T.8
Hayashi, M.9
-
87
-
-
75149122361
-
The (pro) renin receptor in health and disease
-
Nguyen, G. The prorenin receptor in health and disease. Ann Med 2010; 42: 3-18.
-
(2010)
Ann Med
, vol.42
, pp. 3-18
-
-
Nguyen, G.1
-
88
-
-
33745824649
-
Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
-
DOI 10.1681/ASN.2006010029
-
Ichihara A, Suzuki F, Nakagawa T, Kaneshiro Y, Takemitsu T, Sakoda M, Nabi AH, Nishiyama A, Sugaya T, Hayashi M, Inagami T. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor deficient mice. J Am Soc Nephrol 2006; 17: 1950-1961. (Pubitemid 44036179)
-
(2006)
Journal of the American Society of Nephrology
, vol.17
, Issue.7
, pp. 1950-1961
-
-
Ichihara, A.1
Suzuki, F.2
Nakagawa, T.3
Kaneshiro, Y.4
Takemitsu, T.5
Sakoda, M.6
Nurun Nabi, A.H.M.7
Nishiyama, A.8
Sugaya, T.9
Hayashi, M.10
Inagami, T.11
-
89
-
-
33750271641
-
The prorenin receptor: Therapeutic consequences
-
Nguyen G, Danser AH. The prorenin receptor: therapeutic consequences. Expert Opin Investig Drugs 2006; 15: 1131-1135.
-
(2006)
Expert Opin Investig Drugs
, vol.15
, pp. 1131-1135
-
-
Nguyen, G.1
Danser, A.H.2
-
90
-
-
30944469631
-
Renin increases mesangial cell transforming growth factor-β1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
-
DOI 10.1038/sj.ki.5000011, PII 5000011
-
Huang Y, Wongamorntham S, Kasting J, McQuillan D, Owens RT, Yu L, Noble NA, Border W. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 2006; 69: 105-113. (Pubitemid 43117745)
-
(2006)
Kidney International
, vol.69
, Issue.1
, pp. 105-113
-
-
Huang, Y.1
Wongamorntham, S.2
Kasting, J.3
McQuillan, D.4
Owens, R.T.5
Yu, L.6
Noble, N.A.7
Border, W.8
-
91
-
-
33750266798
-
Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II
-
DOI 10.1161/01.HYP.0000240064.19301.1b, PII 0000426820061000000013
-
Saris JJ, Hoen PA, Garrelds IM, Dekkers DH, den Dunnen JT, Lamers JM, Jan Danser AH. Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II. Hypertension 2006; 48: 564-571. (Pubitemid 44843857)
-
(2006)
Hypertension
, vol.48
, Issue.4
, pp. 564-571
-
-
Saris, J.J.1
'T Hoen, P.A.C.2
Garrelds, I.M.3
Dekkers, D.H.W.4
Den Dunnen, J.T.5
Lamers, J.M.J.6
Danser, A.H.J.7
-
92
-
-
76349122414
-
Signal transduction of the prorenin receptor as a novel therapeutic target for preventing end organ damage
-
Funke-Kaiser H, Zollmann FS, Schefe JH, Unger T. Signal transduction of the prorenin receptor as a novel therapeutic target for preventing end organ damage. Hypertens Res 2010; 33: 98-104.
-
(2010)
Hypertens Res
, vol.33
, pp. 98-104
-
-
Funke-Kaiser, H.1
Zollmann, F.S.2
Schefe, J.H.3
Unger, T.4
-
93
-
-
37849044605
-
Prorenin receptor-mediated activation of mitogenactivated protein kinases in human vascular smooth muscle cells
-
Sakoda M, Ichihara A, Kaneshiro Y, Takemitsu T, Nakazato Y, Nabi AH, Nakagawa T, Suzuki F, Inagami T, Itoh H. Prorenin receptor-mediated activation of mitogenactivated protein kinases in human vascular smooth muscle cells. Hypertens Res 2007; 30: 1139-1146.
-
(2007)
Hypertens Res
, vol.30
, pp. 1139-1146
-
-
Sakoda, M.1
Ichihara, A.2
Kaneshiro, Y.3
Takemitsu, T.4
Nakazato, Y.5
Nabi, A.H.6
Nakagawa, T.7
Suzuki, F.8
Inagami, T.9
Itoh, H.10
-
94
-
-
60949099315
-
Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release
-
He M, Zhang L, Shao Y, Wang X, Huang Y, Yao T, Lu L. Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release. Eur J Pharmacol 2009; 606: 155-161.
-
(2009)
Eur J Pharmacol
, vol.606
, pp. 155-161
-
-
He, M.1
Zhang, L.2
Shao, Y.3
Wang, X.4
Huang, Y.5
Yao, T.6
Lu, L.7
-
95
-
-
77649171183
-
Prorenin receptor contributes to diabetic nephropathy through enhancing renal inflammation
-
Matavelli LC, Huang J, Siragy HM. Prorenin receptor contributes to diabetic nephropathy through enhancing renal inflammation. Clin Exp Pharmacol Physiol 2010; 37: 277-282.
-
(2010)
Clin Exp Pharmacol Physiol
, vol.37
, pp. 277-282
-
-
Matavelli, L.C.1
Huang, J.2
Siragy, H.M.3
-
96
-
-
67650236573
-
Prorenin receptor-mediated signal transduction and tissue reninangiotensin system contribute to diabetes-induced retinal inflammation
-
Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S. Prorenin receptor-mediated signal transduction and tissue reninangiotensin system contribute to diabetes-induced retinal inflammation. Diabetes 2009; 58: 1625-1633.
-
(2009)
Diabetes
, vol.58
, pp. 1625-1633
-
-
Satofuka, S.1
Ichihara, A.2
Nagai, N.3
Noda, K.4
Ozawa, Y.5
Fukamizu, A.6
Tsubota, K.7
Itoh, H.8
Oike, Y.9
Ishida, S.10
-
97
-
-
39749098706
-
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
-
DOI 10.1161/HYPERTENSIONAHA.107.101444
-
Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, Dechend R, Fiebeler A, Burckle C, Contrepas A, Jan Danser AH, Bader M, Nguyen G, Luft FC, Muller DN. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension 2008; 51: 682-688. (Pubitemid 351301521)
-
(2008)
Hypertension
, vol.51
, Issue.3
, pp. 682-688
-
-
Feldt, S.1
Batenburg, W.W.2
Mazak, I.3
Maschke, U.4
Wellner, M.5
Kvakan, H.6
Dechend, R.7
Fiebeler, A.8
Burckle, C.9
Contrepas, A.10
Danser, A.H.J.11
Bader, M.12
Nguyen, G.13
Luft, F.C.14
Muller, D.N.15
-
98
-
-
56749090710
-
Prorenin engages the prorenin receptor like renin and both ligand activities are unopposed by aliskiren
-
Schefe JH, Neumann C, Goebel M, Danser J, Kirsch S, Gust R, Kintscher U, Unger T, Funke-Kaiser H. Prorenin engages the prorenin receptor like renin and both ligand activities are unopposed by aliskiren. J Hypertens 2008; 26: 1787-1794.
-
(2008)
J Hypertens
, vol.26
, pp. 1787-1794
-
-
Schefe, J.H.1
Neumann, C.2
Goebel, M.3
Danser, J.4
Kirsch, S.5
Gust, R.6
Kintscher, U.7
Unger, T.8
Funke-Kaiser, H.9
-
99
-
-
35848948398
-
Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
-
DOI 10.1097/HJH.0b013e3282f05bae, PII 0000487220071200000013
-
Batenburg WW, Krop M, Garrelds IM, de Vries R, de Bruin RJA, Burcklé CA, Mü ller DN, Bader M, Nguyen G, Danser AH. Prorenin is the endogenous agonist of the prorenin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human prorenin receptor. J Hypertens 2007; 25: 2441-2453. (Pubitemid 350060383)
-
(2007)
Journal of Hypertension
, vol.25
, Issue.12
, pp. 2441-2453
-
-
Batenburg, W.W.1
Krop, M.2
Garrelds, I.M.3
De Vries, R.4
De Bruin, R.J.A.5
Burckle, C.A.6
Muller, D.N.7
Bader, M.8
Nguyen, G.9
Danser, A.H.J.10
-
100
-
-
54049106595
-
Cardiovascular effects of prorenin blockade in genetically hypertensive rats (SHR) on normal and high salt diet
-
Susic D, Zhou X, Frohlich ED, Lippton H, Knight M. Cardiovascular effects of prorenin blockade in genetically hypertensive rats (SHR) on normal and high salt diet. Am J Physiol Heart Circ Physiol 2008; 295: H1117-H1121.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Susic, D.1
Zhou, X.2
Frohlich, E.D.3
Lippton, H.4
Knight, M.5
-
101
-
-
9644283069
-
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the 'handle' region for nonproteolytic activation of prorenin
-
DOI 10.1172/JCI200421398
-
Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, Koura Y, Nishiyama A, Okada H, Uddin MN, Nabi AH, Ishida Y, Inagami T, Saruta T. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the handle region for nonproteolytic activation of prorenin. J Clin Invest 2004; 114: 1128-1135. (Pubitemid 39578702)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.8
, pp. 1128-1135
-
-
Ichihara, A.1
Hayashi, M.2
Kaneshiro, Y.3
Suzuki, F.4
Nakagawa, T.5
Tada, Y.6
Koura, Y.7
Nishiyama, A.8
Okada, H.9
Uddin, M.N.10
Nabi, A.H.M.N.11
Ishida, Y.12
Inagami, T.13
Saruta, T.14
-
102
-
-
34447272037
-
Regression of nephropathy developed in diabetes by (pro)renin receptor blockade
-
DOI 10.1681/ASN.2006080820
-
Takahashi H, Ichihara A, Kaneshiro Y, Inomata K, Sakoda M, Takemitsu T, Nishiyama A, Itoh H. Regression of nephropathy developed in diabetes by prorenin receptor blockade. J Am Soc Nephrol 2007; 18: 2054-2061. (Pubitemid 47041071)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.7
, pp. 2054-2061
-
-
Takahashi, H.1
Ichihara, A.2
Kaneshiro, Y.3
Inomata, K.4
Sakoda, M.5
Takemitsu, T.6
Nishiyama, A.7
Itoh, H.8
-
104
-
-
33644789557
-
Renin inhibition with aliskiren: Where are we now, and where are we going?
-
DOI 10.1097/01.hjh.0000202812.72341.99, PII 0000487220060200000004
-
Azizi M, Webb R, Nussberger J, Hollenberg NK. Renin inhibition with aliskiren: where are we now, and where are we going? J Hypertens 2006; 24: 243-256. (Pubitemid 43348229)
-
(2006)
Journal of Hypertension
, vol.24
, Issue.2
, pp. 243-256
-
-
Azizi, M.1
Webb, R.2
Nussberger, J.3
Hollenberg, N.K.4
-
105
-
-
73349109829
-
Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver
-
Campbell DJ, Karam H, Ménard J, Bruneval P, Mullins JJ. Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver. Hypertension 2009; 54: 1248-1253.
-
(2009)
Hypertension
, vol.54
, pp. 1248-1253
-
-
Campbell, D.J.1
Karam, H.2
Ménard, J.3
Bruneval, P.4
Mullins, J.J.5
-
106
-
-
37349054998
-
Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: Absence of prorenin-induced glomerulosclerosis
-
DOI 10.1097/HJH.0b013e3282f0ab66, PII 0000487220080100000017
-
Peters B, Grisk O, Becher B, Wanka H, Kuttler B, Ludemann J, Lorenz G, Rettig R, Mullins JJ, Peters J. Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis. J Hypertens 2008; 26: 102-109. (Pubitemid 350301935)
-
(2008)
Journal of Hypertension
, vol.26
, Issue.1
, pp. 102-109
-
-
Peters, B.1
Grisk, O.2
Becher, B.3
Wanka, H.4
Kuttler, B.5
Ludemann, J.6
Lorenz, G.7
Rettig, R.8
Mullins, J.J.9
Peters, J.10
-
107
-
-
77749239824
-
Possible roles of human prorenin receptor suggested by recent clinical and experimental findings
-
Ichihara A, Sakoda M, Kurauchi-Mito A, Narita T, Kinouchi K, Murohashi-Bokuda K, Itoh H. Possible roles of human prorenin receptor suggested by recent clinical and experimental findings. Hypertens Res 2010; 33: 177-180.
-
(2010)
Hypertens Res
, vol.33
, pp. 177-180
-
-
Ichihara, A.1
Sakoda, M.2
Kurauchi-Mito, A.3
Narita, T.4
Kinouchi, K.5
Murohashi-Bokuda, K.6
Itoh, H.7
-
108
-
-
33845608395
-
A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
-
DOI 10.1161/01.RES.0000251700.00994.0d, PII 0000301220061222000011
-
Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP, Ruiz P, Unger T, Funke-Kaiser H. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 2006; 99: 1355-1366. (Pubitemid 44949671)
-
(2006)
Circulation Research
, vol.99
, Issue.12
, pp. 1355-1366
-
-
Schefe, J.H.1
Menk, M.2
Reinemund, J.3
Effertz, K.4
Hobbs, R.M.5
Pandolfi, P.P.6
Ruiz, P.7
Unger, T.8
Funke-Kaiser, H.9
-
109
-
-
67049144916
-
Soluble form of the prorenin receptor generated by intracellular cleavage by furin is secreted in plasma
-
Cousin C, Bracquart D, Contrepas A, Corvol P, Muller L, Nguyen G. Soluble form of the prorenin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension 2009; 53: 1077-1082.
-
(2009)
Hypertension
, vol.53
, pp. 1077-1082
-
-
Cousin, C.1
Bracquart, D.2
Contrepas, A.3
Corvol, P.4
Muller, L.5
Nguyen, G.6
-
110
-
-
78149267757
-
A redox switch in angiotensinogen modulates angiotensin release
-
Zhou A, Carrell RW, Murphy MP, Wei Z, Yan Y, Stanley PL, Stein PE, Broughton Pipkin F, Read RJ. A redox switch in angiotensinogen modulates angiotensin release. Nature 2010; 468: 108-111.
-
(2010)
Nature
, vol.468
, pp. 108-111
-
-
Zhou, A.1
Carrell, R.W.2
Murphy, M.P.3
Wei, Z.4
Yan, Y.5
Stanley, P.L.6
Stein, P.E.7
Broughton Pipkin, F.8
Read, R.J.9
-
111
-
-
33750592956
-
Prorenin and its ancient receptor
-
DOI 10.1161/01.HYP.0000241132.48495.df, PII 0000426820061000000007
-
Burcklé C, Bader M. Prorenin and its ancient receptor. Hypertension 2006; 48: 549-551. (Pubitemid 44843851)
-
(2006)
Hypertension
, vol.48
, Issue.4
, pp. 549-551
-
-
Burckle, C.1
Bader, M.2
-
112
-
-
77954762963
-
The prorenin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes
-
Kinouchi K, Ichihara A, Sano M, Sun-Wada GH, Wada Y, Kurauchi-Mito A, Bokuda K, Narita T, Oshima Y, Sakoda M, Tamai Y, Sato H, Fukuda K, Itoh H. The prorenin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes. Circ Res 2010; 107: 30-34.
-
(2010)
Circ Res
, vol.107
, pp. 30-34
-
-
Kinouchi, K.1
Ichihara, A.2
Sano, M.3
Sun-Wada, G.H.4
Wada, Y.5
Kurauchi-Mito, A.6
Bokuda, K.7
Narita, T.8
Oshima, Y.9
Sakoda, M.10
Tamai, Y.11
Sato, H.12
Fukuda, K.13
Itoh, H.14
-
113
-
-
68549111147
-
The prorenin receptor: Site-specific and functional linkage to the vacuolar H-ATPase in the kidney
-
Advani A, Kelly DJ, Cox AJ, White KE, Advani SL, Thai K, Connelly KA, Yuen D, Trogadis J, Herzenberg AM, Kuliszewski MA, Leong-Poi H, Gilbert RE. The prorenin receptor: site-specific and functional linkage to the vacuolar H-ATPase in the kidney. Hypertension 2009; 54: 261-269.
-
(2009)
Hypertension
, vol.54
, pp. 261-269
-
-
Advani, A.1
Kelly, D.J.2
Cox, A.J.3
White, K.E.4
Advani, S.L.5
Thai, K.6
Connelly, K.A.7
Yuen, D.8
Trogadis, J.9
Herzenberg, A.M.10
Kuliszewski, M.A.11
Leong-Poi, H.12
Gilbert, R.E.13
-
114
-
-
33644935227
-
The V-type H+ ATPase: Molecular structure and function, physiological roles and regulation
-
Beyenbach KW, Wieczorek H. The V-type H+ ATPase: molecular structure and function, physiological roles and regulation. J Exp Biol 2006; 209: 577-589.
-
(2006)
J Exp Biol
, vol.209
, pp. 577-589
-
-
Beyenbach, K.W.1
Wieczorek, H.2
-
115
-
-
4444220604
-
Identification of 315 genes essential for early zebrafish development
-
DOI 10.1073/pnas.0403929101
-
Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, Hopkins N. Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci USA 2004; 101: 12792-12797. (Pubitemid 39167537)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.35
, pp. 12792-12797
-
-
Amsterdam, A.1
Nissen, R.M.2
Sun, Z.3
Swindell, E.C.4
Farrington, S.5
Hopkins, N.6
-
116
-
-
42649098660
-
Expression of prorenin receptor in mouse embryonic and newborn kidney and proliferative effect of soluble (P)RR on mesangial cells [Abstract]
-
Contrepas A, Praizovic N, Duong Van Huyen JP, Lelievre-Pegorier M, Corvol P, Nguyen G. Expression of prorenin receptor in mouse embryonic and newborn kidney and proliferative effect of soluble (P)RR on mesangial cells [Abstract]. Hypertension 2007; 50: e145.
-
(2007)
Hypertension
, vol.50
-
-
Contrepas, A.1
Praizovic, N.2
Duong Van Huyen, J.P.3
Lelievre-Pegorier, M.4
Corvol, P.5
Nguyen, G.6
-
117
-
-
20244369597
-
A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor
-
DOI 10.1093/hmg/ddi094
-
Ramser J, Abidi FE, Burckle CA, Lenski C, Toriello H, Wen G, Lubs HA, Engert S, Stevenson RE, Meindl A, Schwartz CE, Nguyen G. A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor. Hum Mol Genet 2005; 14: 1019-1027. (Pubitemid 40575877)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.8
, pp. 1019-1027
-
-
Ramser, J.1
Abidi, F.E.2
Burckle, C.A.3
Lenski, C.4
Toriello, H.5
Wen, G.6
Lubs, H.A.7
Engert, S.8
Stevenson, R.E.9
Meindl, A.10
Schwartz, C.E.11
Nguyen, G.12
-
118
-
-
77954756914
-
Physiology of the prorenin receptor: Wnt of change?
-
Sihn G, Rousselle A, Vilianovitch L, Burckle C, Bader M. Physiology of the prorenin receptor: Wnt of change? Kidney Int 2010; 78: 246-256.
-
(2010)
Kidney Int
, vol.78
, pp. 246-256
-
-
Sihn, G.1
Rousselle, A.2
Vilianovitch, L.3
Burckle, C.4
Bader, M.5
-
119
-
-
0036341207
-
Signal transduction and endocytosis: Close encounters of many kinds
-
Sorkin A, Von Zastrow M. Signal transduction and endocytosis: close encounters of many kinds. Nat Rev Mol Cell Biol 2002; 3: 600-614.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 600-614
-
-
Sorkin, A.1
Von Zastrow, M.2
-
120
-
-
0030832059
-
Direct measurement of endosomal pH in living cells of the rat yolk sac epithelium by laser confocal microscopy
-
Ichimura T, Hatae T, Ishida T. Direct measurement of endosomal pH in living cells of the rat yolk sac epithelium by laser confocal microscopy. Eur J Cell Biol 1997; 74: 41-48. (Pubitemid 27416893)
-
(1997)
European Journal of Cell Biology
, vol.74
, Issue.1
, pp. 41-48
-
-
Ichimura, T.1
Hatae, T.2
Ishida, T.3
-
121
-
-
33947242782
-
The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling
-
DOI 10.1016/j.nbd.2006.12.004, PII S0969996106003160
-
George A, Leahy H, Zhou J, Morin PJ. The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling. Neurobiol Dis 2007; 26: 125-133. (Pubitemid 46436492)
-
(2007)
Neurobiology of Disease
, vol.26
, Issue.1
, pp. 125-133
-
-
George, A.1
Leahy, H.2
Zhou, J.3
Morin, P.J.4
-
122
-
-
0041470133
-
Dishevelled 2 recruits β-arrestin 2 to mediate Wnt5A-stimulated endocytosis of frizzled 4
-
DOI 10.1126/science.1082808
-
Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 2003; 301: 1391-1394. (Pubitemid 37075817)
-
(2003)
Science
, vol.301
, Issue.5638
, pp. 1391-1394
-
-
Chen, W.1
Ten Berge, D.2
Brown, J.3
Ahn, S.4
Hu, L.A.5
Miller, W.E.6
Caron, M.G.7
Barak, L.S.8
Nusse, R.9
Lefkowitz, R.J.10
-
123
-
-
42249089770
-
The putative prorenin receptor blocker HRP fails to prevent prorenin signaling
-
Feldt S, Maschke U, Dechend R, Luft FC, Muller DN. The putative prorenin receptor blocker HRP fails to prevent prorenin signaling. J Am Soc Nephrol 2008; 19: 743-748.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 743-748
-
-
Feldt, S.1
Maschke, U.2
Dechend, R.3
Luft, F.C.4
Muller, D.N.5
-
124
-
-
39749098706
-
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
-
DOI 10.1161/HYPERTENSIONAHA.107.101444
-
Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, Dechend R, Fiebeler A, Burckle C, Contrepas A, Jan Danser AH, Bader M, Nguyen G, Luft FC, Muller DN. Prorenin and renin induced extracellular signal regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension 2008; 51: 682-688. (Pubitemid 351301521)
-
(2008)
Hypertension
, vol.51
, Issue.3
, pp. 682-688
-
-
Feldt, S.1
Batenburg, W.W.2
Mazak, I.3
Maschke, U.4
Wellner, M.5
Kvakan, H.6
Dechend, R.7
Fiebeler, A.8
Burckle, C.9
Contrepas, A.10
Danser, A.H.J.11
Bader, M.12
Nguyen, G.13
Luft, F.C.14
Muller, D.N.15
-
125
-
-
39749088803
-
(Pro)renin receptor peptide inhibitor 'Handle-region' peptide does not affect hypertensive nephrosclerosis in Goldblatt rats
-
DOI 10.1161/HYPERTENSIONAHA.107.101493
-
Muller DN, Klanke B, Feldt S, Cordasic N, Hartner A, Schmieder RE, Luft FC, Hilgers KF. prorenin receptor peptide inhibitor 'handle-region' peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. Hypertension 2008; 51: 676-681. (Pubitemid 351301520)
-
(2008)
Hypertension
, vol.51
, Issue.3
, pp. 676-681
-
-
Muller, D.N.1
Klanke, B.2
Feldt, S.3
Cordasic, N.4
Hartner, A.5
Schmieder, R.E.6
Luft, F.C.7
Hilgers, K.F.8
-
126
-
-
4644245032
-
Renal vacuolar H+-ATPase
-
Wagner CA, Finberg KE, Breton S, Marshansky V, Brown D, Geibel JP. Renal vacuolar H+-ATPase. Physiol Rev 2004; 84: 1263-1314.
-
(2004)
Physiol Rev
, vol.84
, pp. 1263-1314
-
-
Wagner, C.A.1
Finberg, K.E.2
Breton, S.3
Marshansky, V.4
Brown, D.5
Geibel, J.P.6
-
127
-
-
45849111800
-
Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip goldblatt hypertensive rats
-
Prieto-Carrasquero MC, Botros FT, Pagan J, Kobori H, Seth DM, Casarini DE, Navar LG. Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip goldblatt hypertensive rats. Hypertension 2008; 51: 1590-1596.
-
(2008)
Hypertension
, vol.51
, pp. 1590-1596
-
-
Prieto-Carrasquero, M.C.1
Botros, F.T.2
Pagan, J.3
Kobori, H.4
Seth, D.M.5
Casarini, D.E.6
Navar, L.G.7
-
128
-
-
34447262612
-
+-ATPase activity in renal acid-secretory intercalated cells from the outer medullary collecting duct
-
DOI 10.1681/ASN.2006070753
-
Rothenberger F, Velic A, Stehberger PA, Kovacikova J, Wagner CA. Angiotensin II stimulates vacuolar H+-ATPase activity in renal acid secretory intercalated cells from the outer medullary collecting duct. J Am Soc Nephrol 2007; 18: 2085-2093. (Pubitemid 47041074)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.7
, pp. 2085-2093
-
-
Rothenberger, F.1
Velic, A.2
Stehberger, P.A.3
Kovacikova, J.4
Wagner, C.A.5
-
129
-
-
38149120571
-
Angiotensin II activates H+-ATPase in type A intercalated cells
-
Pech V, Zheng W, Pham TD, Verlander JW, Wall SM. Angiotensin II activates H+-ATPase in type A intercalated cells. J Am Soc Nephrol 2008; 19: 84-91.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 84-91
-
-
Pech, V.1
Zheng, W.2
Pham, T.D.3
Verlander, J.W.4
Wall, S.M.5
-
130
-
-
34249881320
-
Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats
-
DOI 10.1681/ASN.2006091062
-
Kaneshiro Y, Ichihara A, Sakoda M, Takemitsu T, Nabi AH, Uddin MN, Nakagawa T, Nishiyama A, Suzuki F, Inagami T, Itoh H. Slowly progressive, angiotensin IIindependent glomerulosclerosis in human prorenin receptor-transgenic rats. J Am Soc Nephrol 2007; 18: 1789-1795. (Pubitemid 46870315)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.6
, pp. 1789-1795
-
-
Kaneshiro, Y.1
Ichihara, A.2
Sakoda, M.3
Takemitsu, T.4
Nabi, A.H.M.N.5
Uddin, M.N.6
Nakagawa, T.7
Nishiyama, A.8
Suzuki, F.9
Inagami, T.10
Itoh, H.11
-
131
-
-
69849089270
-
Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria
-
Dai C, Stolz DB, Kiss LP, Monga SP, Holzman LB, Liu Y. Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria. J Am Soc Nephrol 2009; 20: 1997-2008.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1997-2008
-
-
Dai, C.1
Stolz, D.B.2
Kiss, L.P.3
Monga, S.P.4
Holzman, L.B.5
Liu, Y.6
-
132
-
-
69949172478
-
Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy
-
Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG. Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Nat Med 2009; 15: 1046-1054.
-
(2009)
Nat Med
, vol.15
, pp. 1046-1054
-
-
Lancaster, M.A.1
Louie, C.M.2
Silhavy, J.L.3
Sintasath, L.4
Decambre, M.5
Nigam, S.K.6
Willert, K.7
Gleeson, J.G.8
-
133
-
-
65249134946
-
Wnt/beta-catenin signaling promotes renal interstitial fibrosis
-
He W, Dai C, Li Y, Zeng G, Monga SP, Liu Y. Wnt/beta-catenin signaling promotes renal interstitial fibrosis. J Am Soc Nephrol 2009; 20: 765-776.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 765-776
-
-
He, W.1
Dai, C.2
Li, Y.3
Zeng, G.4
Monga, S.P.5
Liu, Y.6
-
134
-
-
33749435799
-
The role of Wnt signalling in cardiac development and tissue remodelling in the mature heart
-
DOI 10.1016/j.cardiores.2006.06.025, PII S0008636306002975
-
Brade T, Männer J, Kühl M. The role of Wnt signalling in cardiac development and tissue remodelling in the mature heart. Cardiovasc Res 2006; 72: 198-209. (Pubitemid 44511910)
-
(2006)
Cardiovascular Research
, vol.72
, Issue.2
, pp. 198-209
-
-
Brade, T.1
Manner, J.2
Kuhl, M.3
-
135
-
-
33846966331
-
Differences between pathological and physiological cardiac hypertrophy: Novel therapeutic strategies to treat heart failure
-
McMullen JR, Jennings GL. Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure. Clin Exp Pharmacol Physiol 2007; 34: 255-262.
-
(2007)
Clin Exp Pharmacol Physiol
, vol.34
, pp. 255-262
-
-
McMullen, J.R.1
Jennings, G.L.2
-
136
-
-
0034597147
-
Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy
-
Haq S, Choukroun G, Kang ZB, Ranu H, Matsui T, Rosenzweig A, Molkentin JD, Alessandrini A, Woodgett J, Hajjar R, Michael A, Force T. Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy. J Cell Biol 2000; 151: 117-130.
-
(2000)
J Cell Biol
, vol.151
, pp. 117-130
-
-
Haq, S.1
Choukroun, G.2
Kang, Z.B.3
Ranu, H.4
Matsui, T.5
Rosenzweig, A.6
Molkentin, J.D.7
Alessandrini, A.8
Woodgett, J.9
Hajjar, R.10
Michael, A.11
Force, T.12
-
137
-
-
33750452307
-
Molecular mechanisms in heart failure: focus on cardiac hypertrophy, inflammation, angiogenesis, and apoptosis
-
DOI 10.1016/j.jacc.2006.07.007, PII S0735109706018080
-
Hilfiker-Kleiner D, Landmesser U, Drexler H. Molecular mechanisms in heart failure: focus on cardiac hypertrophy, inflammation, angiogenesis, and apoptosis. J Am Coll Cardiol 2006; 48: A56-A66. (Pubitemid 44648642)
-
(2006)
Journal of the American College of Cardiology
, vol.48
, Issue.SUPPL. 9
-
-
Hilfiker-Kleiner, D.1
Landmesser, U.2
Drexler, H.3
-
138
-
-
33745029734
-
The β-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy
-
DOI 10.1128/MCB.02157-05
-
Chen X, Shevtsov SP, Hsich E, Cui L, Haq S, Aronovitz M, Kerkelä R, Molkentin JD, Liao R, Salomon RN, Patten R, Force T. The beta-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy. Mol Cell Biol 2006; 26: 4462-4473. (Pubitemid 43877567)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.12
, pp. 4462-4473
-
-
Chen, X.1
Shevtsov, S.P.2
Hsich, E.3
Cui, L.4
Haq, S.5
Aronovitz, M.6
Kerkela, R.7
Molkentin, J.D.8
Liao, R.9
Salomon, R.N.10
Patten, R.11
Force, T.12
-
139
-
-
77951499583
-
Prorenin, renin, and their receptor: Moving targets
-
Reudelhuber TL. Prorenin, renin, and their receptor: moving targets. Hypertension 2010; 55: 1071-1074.
-
(2010)
Hypertension
, vol.55
, pp. 1071-1074
-
-
Reudelhuber, T.L.1
-
140
-
-
38649119156
-
The second life of the prorenin receptor
-
Bader M. The second life of the prorenin receptor. J Renin Angiotensin Aldosterone Syst 2007; 8: 205-208.
-
(2007)
J Renin Angiotensin Aldosterone Syst
, vol.8
, pp. 205-208
-
-
Bader, M.1
-
141
-
-
12144289950
-
Vascular development in the retina and inner ear: Control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair
-
DOI 10.1016/S0092-8674(04)00216-8, PII S0092867404002168
-
Xu Q, Wang Y, Dabdoub A, Smallwood PM, Williams J, Woods C, Kelley MW, Jiang L, Tasman W, Zhang K, Nathans J. Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell 2004; 116: 883-895. (Pubitemid 38410732)
-
(2004)
Cell
, vol.116
, Issue.6
, pp. 883-895
-
-
Xu, Q.1
Wang, Y.2
Dabdoub, A.3
Smallwood, P.M.4
Williams, J.5
Woods, C.6
Kelley, M.W.7
Jiang, L.8
Tasman, W.9
Zhang, K.10
Nathans, J.11
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