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Volumn 1069, Issue 1, 2006, Pages 39-46

Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs

Author keywords

Cranial window; Global cerebral ischemia; Hypercapnia; Kainate; Quinolinic acid

Indexed keywords

AMPA RECEPTOR; KAINIC ACID; KAINIC ACID RECEPTOR; KYNURENIC ACID; KYNURENINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; QUINOLINIC ACID; TRYPTOPHAN;

EID: 31344463756     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.11.033     Document Type: Article
Times cited : (14)

References (60)
  • 1
    • 1642296618 scopus 로고    scopus 로고
    • Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro
    • A. Alt, B. Weiss, A.M. Ogden, J.L. Knauss, J. Oler, K. Ho, T.H. Large, and D. Bleakman Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro Neuropharmacology 46 2004 793 806
    • (2004) Neuropharmacology , vol.46 , pp. 793-806
    • Alt, A.1    Weiss, B.2    Ogden, A.M.3    Knauss, J.L.4    Oler, J.5    Ho, K.6    Large, T.H.7    Bleakman, D.8
  • 2
    • 0023934896 scopus 로고
    • The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection
    • P. Andinë, A. Lehmann, K. Ellren, E. Wennberg, I. Kjellmer, T. Nielsen, and H. Hagberg The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection Neurosci. Lett. 90 1988 208 212
    • (1988) Neurosci. Lett. , vol.90 , pp. 208-212
    • Andinë, P.1    Lehmann, A.2    Ellren, K.3    Wennberg, E.4    Kjellmer, I.5    Nielsen, T.6    Hagberg, H.7
  • 3
    • 0037111481 scopus 로고    scopus 로고
    • Age dependent NMDA contribution to impaired hypotensive cerebral hemodynamics following brain injury
    • W.M. Armstead Age dependent NMDA contribution to impaired hypotensive cerebral hemodynamics following brain injury Brain Res. Dev. Brain Res. 139 2002 19 28
    • (2002) Brain Res. Dev. Brain Res. , vol.139 , pp. 19-28
    • Armstead, W.M.1
  • 4
    • 8444235445 scopus 로고    scopus 로고
    • NMDA and age dependent cerebral hemodynamics after traumatic brain injury
    • W.M. Armstead NMDA and age dependent cerebral hemodynamics after traumatic brain injury Exp. Toxicol. Pathol. 56 2004 75 81
    • (2004) Exp. Toxicol. Pathol. , vol.56 , pp. 75-81
    • Armstead, W.M.1
  • 6
    • 0032529087 scopus 로고    scopus 로고
    • Temporal and spatial changes of quinolinic acid immunoreactivity in the gerbil hippocampus following transient cerebral ischemia
    • S. Baratte, A. Molinari, O. Veneroni, C. Speciale, L. Benatti, and P. Salvati Temporal and spatial changes of quinolinic acid immunoreactivity in the gerbil hippocampus following transient cerebral ischemia Brain Res. Mol. Brain Res. 59 1998 50 57
    • (1998) Brain Res. Mol. Brain Res. , vol.59 , pp. 50-57
    • Baratte, S.1    Molinari, A.2    Veneroni, O.3    Speciale, C.4    Benatti, L.5    Salvati, P.6
  • 7
    • 0029822958 scopus 로고    scopus 로고
    • Differential effects of short-term hypoxia and hypercapnia on N-methyl-d-aspartate-induced cerebral vasodilatation in piglets
    • F. Bari, R.A. Errico, T.M. Louis, and D.W. Busija Differential effects of short-term hypoxia and hypercapnia on N-methyl-d-aspartate-induced cerebral vasodilatation in piglets Stroke 27 1996 1634 1639 (discussion 1639-1640)
    • (1996) Stroke , vol.27 , pp. 1634-1639
    • Bari, F.1    Errico, R.A.2    Louis, T.M.3    Busija, D.W.4
  • 8
    • 0030955925 scopus 로고    scopus 로고
    • Kainate-induced cerebrovascular dilation is resistant to ischemia in piglets
    • F. Bari, T.M. Louis, and D.W. Busija Kainate-induced cerebrovascular dilation is resistant to ischemia in piglets Stroke 28 1997 1272 1276 (discussion 1277)
    • (1997) Stroke , vol.28 , pp. 1272-1276
    • Bari, F.1    Louis, T.M.2    Busija, D.W.3
  • 9
    • 0031984365 scopus 로고    scopus 로고
    • Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets
    • F. Bari, T.M. Louis, and D.W. Busija Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets Stroke 29 1998 222 227 (discussion 227-228)
    • (1998) Stroke , vol.29 , pp. 222-227
    • Bari, F.1    Louis, T.M.2    Busija, D.W.3
  • 10
    • 0032509789 scopus 로고    scopus 로고
    • Inhibitory effects of hypoxia and adenosine on N-methyl-d-aspartate- induced pial arteriolar dilation in piglets
    • F. Bari, C.R. Thore, T.M. Louis, and D.W. Busija Inhibitory effects of hypoxia and adenosine on N-methyl-d-aspartate-induced pial arteriolar dilation in piglets Brain Res. 780 1998 237 244
    • (1998) Brain Res. , vol.780 , pp. 237-244
    • Bari, F.1    Thore, C.R.2    Louis, T.M.3    Busija, D.W.4
  • 11
    • 0031975011 scopus 로고    scopus 로고
    • Cerebral ischemia/reperfusion increases endothelial nitric oxide synthase levels by an indomethacin-sensitive mechanism
    • T.C. Beasley, F. Bari, C. Thore, N. Thrikawala, T. Louis, and D. Busija Cerebral ischemia/reperfusion increases endothelial nitric oxide synthase levels by an indomethacin-sensitive mechanism J. Cereb. Blood Flow Metab. 18 1998 88 96
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 88-96
    • Beasley, T.C.1    Bari, F.2    Thore, C.3    Thrikawala, N.4    Louis, T.5    Busija, D.6
  • 12
    • 0024544716 scopus 로고
    • Kynurenic acid inhibits the activation of kainic and N-methyl-d-aspartic acid-sensitive ionotropic receptors by a different mechanism
    • M. Bertolino, S. Vicini, and E. Costa Kynurenic acid inhibits the activation of kainic and N-methyl-d-aspartic acid-sensitive ionotropic receptors by a different mechanism Neuropharmacology 28 1989 453 457
    • (1989) Neuropharmacology , vol.28 , pp. 453-457
    • Bertolino, M.1    Vicini, S.2    Costa, E.3
  • 13
    • 1942420878 scopus 로고    scopus 로고
    • Animal models of obstetric complications in relation to schizophrenia
    • P. Boksa Animal models of obstetric complications in relation to schizophrenia Brain Res. Brain Res. Rev. 45 2004 1 17
    • (2004) Brain Res. Brain Res. Rev. , vol.45 , pp. 1-17
    • Boksa, P.1
  • 14
    • 0024436325 scopus 로고
    • Dilator effects of amino acid neurotransmitters on piglet pial arterioles
    • D.W. Busija, and C.W. Leffler Dilator effects of amino acid neurotransmitters on piglet pial arterioles Am. J. Physiol. 257 1989 H1200 H1203
    • (1989) Am. J. Physiol. , vol.257
    • Busija, D.W.1    Leffler, C.W.2
  • 17
    • 0033805549 scopus 로고    scopus 로고
    • Perinatal kynurenine pathway metabolism in the normal and asphyctic rat brain
    • G. Ceresoli-Borroni, and R. Schwarcz Perinatal kynurenine pathway metabolism in the normal and asphyctic rat brain Amino Acids 19 2000 311 323
    • (2000) Amino Acids , vol.19 , pp. 311-323
    • Ceresoli-Borroni, G.1    Schwarcz, R.2
  • 18
    • 0034915008 scopus 로고    scopus 로고
    • Neonatal asphyxia in rats: Acute effects on cerebral kynurenine metabolism
    • G. Ceresoli-Borroni, and R. Schwarcz Neonatal asphyxia in rats: acute effects on cerebral kynurenine metabolism Pediatr. Res. 50 2001 231 235
    • (2001) Pediatr. Res. , vol.50 , pp. 231-235
    • Ceresoli-Borroni, G.1    Schwarcz, R.2
  • 19
    • 0028799654 scopus 로고
    • Calcium: Still center-stage in hypoxic-ischemic neuronal death
    • D.W. Choi Calcium: still center-stage in hypoxic-ischemic neuronal death Trends Neurosci. 18 1995 58 60
    • (1995) Trends Neurosci. , vol.18 , pp. 58-60
    • Choi, D.W.1
  • 20
    • 0033502043 scopus 로고    scopus 로고
    • Kynurenine hydroxylase inhibitors reduce ischemic brain damage: Studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl) thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia
    • A. Cozzi, R. Carpenedo, and F. Moroni Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia J. Cereb. Blood Flow Metab. 19 1999 771 777
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 771-777
    • Cozzi, A.1    Carpenedo, R.2    Moroni, F.3
  • 23
  • 25
    • 0027514356 scopus 로고
    • Nitric oxide mediates vasodilatation in response to activation of N-methyl-d-aspartate receptors in brain
    • F.M. Faraci, and K.R. Breese Nitric oxide mediates vasodilatation in response to activation of N-methyl-d-aspartate receptors in brain Circ. Res. 72 1993 476 480
    • (1993) Circ. Res. , vol.72 , pp. 476-480
    • Faraci, F.M.1    Breese, K.R.2
  • 26
    • 0028128219 scopus 로고
    • Responses of cerebral arterioles to kainate
    • F.M. Faraci, K.R. Breese, and D.D. Heistad Responses of cerebral arterioles to kainate Stroke 25 1994 2080 2083 (discussion 2084)
    • (1994) Stroke , vol.25 , pp. 2080-2083
    • Faraci, F.M.1    Breese, K.R.2    Heistad, D.D.3
  • 27
    • 0030890433 scopus 로고    scopus 로고
    • Regulation of cerebral microvessels by glutamatergic mechanisms
    • A. Fergus, and K.S. Lee Regulation of cerebral microvessels by glutamatergic mechanisms Brain Res. 754 1997 35 45
    • (1997) Brain Res. , vol.754 , pp. 35-45
    • Fergus, A.1    Lee, K.S.2
  • 28
    • 0025606651 scopus 로고
    • Results of N-methyl-d-aspartate antagonists in perinatal cerebral asphyxia therapy
    • L.M. Ford Results of N-methyl-d-aspartate antagonists in perinatal cerebral asphyxia therapy Pediatr. Neurol. 6 1990 363 366
    • (1990) Pediatr. Neurol. , vol.6 , pp. 363-366
    • Ford, L.M.1
  • 29
    • 0021186590 scopus 로고
    • Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid
    • A.C. Foster, A. Vezzani, E.D. French, and R. Schwarcz Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid Neurosci. Lett. 48 1984 273 278
    • (1984) Neurosci. Lett. , vol.48 , pp. 273-278
    • Foster, A.C.1    Vezzani, A.2    French, E.D.3    Schwarcz, R.4
  • 30
    • 9644270316 scopus 로고    scopus 로고
    • Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease
    • P. Guidetti, R.E. Luthi-Carter, S.J. Augood, and R. Schwarcz Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease Neurobiol. Dis. 17 2004 455 461
    • (2004) Neurobiol. Dis. , vol.17 , pp. 455-461
    • Guidetti, P.1    Luthi-Carter, R.E.2    Augood, S.J.3    Schwarcz, R.4
  • 31
    • 15844427653 scopus 로고    scopus 로고
    • Involvement of quinolinic acid in AIDS dementia complex
    • G.J. Guillemin, S.J. Kerr, and B.J. Brew Involvement of quinolinic acid in AIDS dementia complex Neurotox. Res. 7 2005 103 123
    • (2005) Neurotox. Res. , vol.7 , pp. 103-123
    • Guillemin, G.J.1    Kerr, S.J.2    Brew, B.J.3
  • 32
    • 0028143946 scopus 로고
    • Hypoxia-ischemia in the neonatal rat brain: Histopathology after post-treatment with NMDA and non-NMDA receptor antagonists
    • H. Hagberg, E. Gilland, N.H. Diemer, and P. Andine Hypoxia-ischemia in the neonatal rat brain: histopathology after post-treatment with NMDA and non-NMDA receptor antagonists Biol. Neonate 66 1994 205 213
    • (1994) Biol. Neonate , vol.66 , pp. 205-213
    • Hagberg, H.1    Gilland, E.2    Diemer, N.H.3    Andine, P.4
  • 34
    • 0030930823 scopus 로고    scopus 로고
    • Species heterogeneity between gerbils and rats: Quinolinate production by microglia and astrocytes and accumulations in response to ischemic brain injury and systemic immune activation
    • M.P. Heyes, K. Saito, C.Y. Chen, M.G. Proescholdt, T.S. Nowak Jr., J. Li, K.E. Beagles, M.A. Proescholdt, M.A. Zito, K. Kawai, and S.P. Markey Species heterogeneity between gerbils and rats: quinolinate production by microglia and astrocytes and accumulations in response to ischemic brain injury and systemic immune activation J. Neurochem. 69 1997 1519 1529
    • (1997) J. Neurochem. , vol.69 , pp. 1519-1529
    • Heyes, M.P.1    Saito, K.2    Chen, C.Y.3    Proescholdt, M.G.4    Nowak Jr., T.S.5    Li, J.6    Beagles, K.E.7    Proescholdt, M.A.8    Zito, M.A.9    Kawai, K.10    Markey, S.P.11
  • 35
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: Physiopathological implications
    • C. Hilmas, E.F. Pereira, M. Alkondon, A. Rassoulpour, R. Schwarcz, and E.X. Albuquerque The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications J. Neurosci. 21 2001 7463 7473
    • (2001) J. Neurosci. , vol.21 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 36
    • 0034991340 scopus 로고    scopus 로고
    • Neurobiology of hypoxic-ischemic injury in the developing brain
    • M.V. Johnston, W.H. Trescher, A. Ishida, and W. Nakajima Neurobiology of hypoxic-ischemic injury in the developing brain Pediatr. Res. 49 2001 735 741
    • (2001) Pediatr. Res. , vol.49 , pp. 735-741
    • Johnston, M.V.1    Trescher, W.H.2    Ishida, A.3    Nakajima, W.4
  • 38
    • 0026725686 scopus 로고
    • Topical arachidonic acid restores pial arteriolar dilation to hypercapnia of postischemic newborn pig brain
    • C.W. Leffler, R. Mirro, W.M. Armstead, and M. Shibata Topical arachidonic acid restores pial arteriolar dilation to hypercapnia of postischemic newborn pig brain Am. J. Physiol. 263 1992 H746 H751
    • (1992) Am. J. Physiol. , vol.263
    • Leffler, C.W.1    Mirro, R.2    Armstead, W.M.3    Shibata, M.4
  • 39
    • 0041529913 scopus 로고    scopus 로고
    • Endogenous level of kynurenic acid and activities of kynurenine aminotransferases following transient global ischemia in the gerbil hippocampus
    • E. Luchowska, P. Luchowski, A. Sarnowska, M. Wielosz, W.A. Turski, and E.M. Urbanska Endogenous level of kynurenic acid and activities of kynurenine aminotransferases following transient global ischemia in the gerbil hippocampus Pol. J. Pharmacol. 55 2003 443 447
    • (2003) Pol. J. Pharmacol. , vol.55 , pp. 443-447
    • Luchowska, E.1    Luchowski, P.2    Sarnowska, A.3    Wielosz, M.4    Turski, W.A.5    Urbanska, E.M.6
  • 40
    • 0028902120 scopus 로고
    • Glutamate-induced cerebral vasodilation is mediated by nitric oxide through N-methyl-d-aspartate receptors
    • W. Meng, J.R. Tobin, and D.W. Busija Glutamate-induced cerebral vasodilation is mediated by nitric oxide through N-methyl-d-aspartate receptors Stroke 26 1995 857 862 (discussion 863)
    • (1995) Stroke , vol.26 , pp. 857-862
    • Meng, W.1    Tobin, J.R.2    Busija, D.W.3
  • 41
    • 0033056044 scopus 로고    scopus 로고
    • Tryptophan metabolism and brain function: Focus on kynurenine and other indole metabolites
    • F. Moroni Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites Eur. J. Pharmacol. 375 1999 87 100
    • (1999) Eur. J. Pharmacol. , vol.375 , pp. 87-100
    • Moroni, F.1
  • 42
    • 0029263410 scopus 로고
    • Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry
    • D.B. Naritsin, R.L. Boni, and S.P. Markey Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry Anal. Chem. 67 1995 863 870
    • (1995) Anal. Chem. , vol.67 , pp. 863-870
    • Naritsin, D.B.1    Boni, R.L.2    Markey, S.P.3
  • 43
    • 0034852744 scopus 로고    scopus 로고
    • Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies
    • G.C. Palmer Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies Curr. Drug Targets 2 2001 241 271
    • (2001) Curr. Drug Targets , vol.2 , pp. 241-271
    • Palmer, G.C.1
  • 44
    • 0025456905 scopus 로고
    • Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-d-aspartate and quisqualate receptors
    • D.K. Patneau, and M.L. Mayer Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-d-aspartate and quisqualate receptors J. Neurosci. 10 1990 2385 2399
    • (1990) J. Neurosci. , vol.10 , pp. 2385-2399
    • Patneau, D.K.1    Mayer, M.L.2
  • 45
    • 0026709272 scopus 로고
    • Some animal models for the study of perinatal asphyxia
    • T.N. Raju Some animal models for the study of perinatal asphyxia Biol. Neonate 62 1992 202 214
    • (1992) Biol. Neonate , vol.62 , pp. 202-214
    • Raju, T.N.1
  • 46
    • 0027319584 scopus 로고
    • Long-term follow-up of term neonates with perinatal asphyxia
    • C.M. Robertson, and N.N. Finer Long-term follow-up of term neonates with perinatal asphyxia Clin. Perinatol. 20 1993 483 500
    • (1993) Clin. Perinatol. , vol.20 , pp. 483-500
    • Robertson, C.M.1    Finer, N.N.2
  • 47
    • 0036083293 scopus 로고    scopus 로고
    • Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles
    • J.S. Robinson, A.L. Fedinec, and C.W. Leffler Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles Am. J. Physiol.: Heart Circ. Physiol. 282 2002 H2371 H2376
    • (2002) Am. J. Physiol.: Heart Circ. Physiol. , vol.282
    • Robinson, J.S.1    Fedinec, A.L.2    Leffler, C.W.3
  • 48
    • 0027459915 scopus 로고
    • Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia
    • K. Saito, T.S. Nowak Jr., S.P. Markey, and M.P. Heyes Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia J. Neurochem. 60 1993 180 192
    • (1993) J. Neurochem. , vol.60 , pp. 180-192
    • Saito, K.1    Nowak Jr., T.S.2    Markey, S.P.3    Heyes, M.P.4
  • 49
    • 0031834430 scopus 로고    scopus 로고
    • Effects of central and peripheral administration of kynurenic acid on hippocampal evoked responses in vivo and in vitro
    • H.E. Scharfman, and J.H. Goodman Effects of central and peripheral administration of kynurenic acid on hippocampal evoked responses in vivo and in vitro Neuroscience 86 1998 751 764
    • (1998) Neuroscience , vol.86 , pp. 751-764
    • Scharfman, H.E.1    Goodman, J.H.2
  • 50
    • 4544386279 scopus 로고    scopus 로고
    • Neuroprotection against ischemic/hypoxic brain damage: Blockers of ionotropic glutamate receptor and voltage sensitive calcium channels
    • A. Schurr Neuroprotection against ischemic/hypoxic brain damage: blockers of ionotropic glutamate receptor and voltage sensitive calcium channels Curr. Drug Targets 5 2004 603 618
    • (2004) Curr. Drug Targets , vol.5 , pp. 603-618
    • Schurr, A.1
  • 51
    • 0036784518 scopus 로고    scopus 로고
    • Manipulation of brain kynurenines: Glial targets, neuronal effects, and clinical opportunities
    • R. Schwarcz, and R. Pellicciari Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities J. Pharmacol. Exp. Ther. 303 2002 1 10
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 1-10
    • Schwarcz, R.1    Pellicciari, R.2
  • 52
    • 0020702374 scopus 로고
    • Quinolinic acid: An endogenous metabolite that produces axon-sparing lesions in rat brain
    • R. Schwarcz, W.O. Whetsell Jr., and R.M. Mangano Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain Science 219 1983 316 318
    • (1983) Science , vol.219 , pp. 316-318
    • Schwarcz, R.1    Whetsell Jr., W.O.2    Mangano, R.M.3
  • 53
    • 0034743617 scopus 로고    scopus 로고
    • Presynaptic alpha7-nicotinic acetylcholine receptors mediate nicotine-induced nitric oxidergic neurogenic vasodilation in porcine basilar arteries
    • M.L. Si, and T.J. Lee Presynaptic alpha7-nicotinic acetylcholine receptors mediate nicotine-induced nitric oxidergic neurogenic vasodilation in porcine basilar arteries J. Pharmacol. Exp. Ther. 298 2001 122 128
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 122-128
    • Si, M.L.1    Lee, T.J.2
  • 54
    • 0037067314 scopus 로고    scopus 로고
    • Alpha7-nicotinic acetylcholine receptors on cerebral perivascular sympathetic nerves mediate choline-induced nitrergic neurogenic vasodilation
    • M.L. Si, and T.J. Lee Alpha7-nicotinic acetylcholine receptors on cerebral perivascular sympathetic nerves mediate choline-induced nitrergic neurogenic vasodilation Circ. Res. 91 2002 62 69
    • (2002) Circ. Res. , vol.91 , pp. 62-69
    • Si, M.L.1    Lee, T.J.2
  • 55
    • 0023039309 scopus 로고
    • Inhibition of excitatory neurotransmission with kynurenate reduces brain edema in neonatal anoxia
    • R.P. Simon, R.S. Young, S. Stout, and J. Cheng Inhibition of excitatory neurotransmission with kynurenate reduces brain edema in neonatal anoxia Neurosci. Lett. 71 1986 361 364
    • (1986) Neurosci. Lett. , vol.71 , pp. 361-364
    • Simon, R.P.1    Young, R.S.2    Stout, S.3    Cheng, J.4
  • 57
    • 0025220952 scopus 로고
    • Sensitivity of hippocampal neurones to kainic acid, and antagonism by kynurenate
    • T.W. Stone Sensitivity of hippocampal neurones to kainic acid, and antagonism by kynurenate Br. J. Pharmacol. 101 1990 847 852
    • (1990) Br. J. Pharmacol. , vol.101 , pp. 847-852
    • Stone, T.W.1
  • 58
    • 0034176154 scopus 로고    scopus 로고
    • Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection
    • T.W. Stone Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection Trends Pharmacol. Sci. 21 2000 149 154
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 149-154
    • Stone, T.W.1
  • 59
    • 0019440926 scopus 로고
    • Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS
    • T.W. Stone, and M.N. Perkins Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS Eur. J. Pharmacol. 72 1981 411 412
    • (1981) Eur. J. Pharmacol. , vol.72 , pp. 411-412
    • Stone, T.W.1    Perkins, M.N.2


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