메뉴 건너뛰기




Volumn 25, Issue 11, 2011, Pages 1835-1848

Minireview: Recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 55; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 80054987727     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1197     Document Type: Review
Times cited : (137)

References (121)
  • 1
    • 33646814424 scopus 로고    scopus 로고
    • Cannabinoid receptors and endocannabi-noids: Evidence for new players
    • Mackie K, Stella N 2006 Cannabinoid receptors and endocannabi-noids: evidence for new players. AAPS J 8:E298-E306
    • (2006) AAPS J , vol.8
    • Mackie, K.1    Stella, N.2
  • 2
    • 35748973885 scopus 로고    scopus 로고
    • Novel cannabinoid receptors
    • Brown AJ 2007 Novel cannabinoid receptors. Br J Pharmacol 152:567-575
    • (2007) Br J Pharmacol , vol.152 , pp. 567-575
    • Brown, A.J.1
  • 5
    • 67749114412 scopus 로고    scopus 로고
    • Is GPR55 an anandamide receptor?
    • Brown AJ, Robin Hiley C 2009 Is GPR55 an anandamide receptor? Vitam Horm 81:111-137
    • (2009) Vitam Horm , vol.81 , pp. 111-137
    • Brown, A.J.1    Robin Hiley, C.2
  • 7
    • 77950630872 scopus 로고    scopus 로고
    • GPR55: Current knowledge and future perspectives of a purported "type-3" cannabinoid receptor
    • Moriconi A, Cerbara I, Maccarrone M, Topai A 2010 GPR55: current knowledge and future perspectives of a purported "type-3" cannabinoid receptor. Curr Med Chem 17:1411-1429
    • (2010) Curr Med Chem , vol.17 , pp. 1411-1429
    • Moriconi, A.1    Cerbara, I.2    Maccarrone, M.3    Topai, A.4
  • 8
    • 78649689791 scopus 로고    scopus 로고
    • GPR55, a lysophosphatidylinositol receptor with cannabinoid sensitivity?
    • Nevalainen T, Irving AJ 2010 GPR55, a lysophosphatidylinositol receptor with cannabinoid sensitivity? Curr Top Med Chem 10: 799-813
    • (2010) Curr Top Med Chem , vol.10 , pp. 799-813
    • Nevalainen, T.1    Irving, A.J.2
  • 9
    • 61349143694 scopus 로고    scopus 로고
    • The enigmatic pharmacology of GPR55
    • Ross RA 2009 The enigmatic pharmacology of GPR55. Trends Pharmacol Sci 30:156-163
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 156-163
    • Ross, R.A.1
  • 10
    • 77952950690 scopus 로고    scopus 로고
    • Pharmacological characterization of GPR55, a putative cannabinoid receptor
    • Sharir H, Abood ME 2010 Pharmacological characterization of GPR55, a putative cannabinoid receptor. Pharmacol Ther 126: 301-313
    • (2010) Pharmacol Ther , vol.126 , pp. 301-313
    • Sharir, H.1    Abood, M.E.2
  • 11
    • 41649096069 scopus 로고
    • The identification of lysophosphatidylinositol and its enzymic conversion to phosphatidylinositol
    • Keenan RW, Hokin LE 1962 The identification of lysophosphatidylinositol and its enzymic conversion to phosphatidylinositol. Biochim Biophys Acta 60:428-430
    • (1962) Biochim Biophys Acta , vol.60 , pp. 428-430
    • Keenan, R.W.1    Hokin, L.E.2
  • 12
    • 41649121638 scopus 로고
    • The enzymatic acylation of lysophosphatidylinositol
    • Keenan RW, Hokin LE 1964 The enzymatic acylation of lysophosphatidylinositol. J Biol Chem 239:2123-2129
    • (1964) J Biol Chem , vol.239 , pp. 2123-2129
    • Keenan, R.W.1    Hokin, L.E.2
  • 13
    • 0022483069 scopus 로고
    • Lysophosphatidylinositol, but not lysophosphatidic acid, stimulates insulin release. A possible role for phospholipase A2 but not de novo synthesis of lysophospholipid in pancreatic islet function
    • Metz SA 1986 Lysophosphatidylinositol, but not lysophosphatidic acid, stimulates insulin release. A possible role for phospholipase A2 but not de novo synthesis of lysophospholipid in pancreatic islet function. Biochem Biophys Res Commun 138:720-727
    • (1986) Biochem Biophys Res Commun , vol.138 , pp. 720-727
    • Metz, S.A.1
  • 14
    • 0024294262 scopus 로고
    • Mobilization of cellular Ca2+ by lysophospholipids in rat islets of Langerhans
    • Metz SA 1988 Mobilization of cellular Ca2+ by lysophospholipids in rat islets of Langerhans. Biochim Biophys Acta 968:239-252
    • (1988) Biochim Biophys Acta , vol.968 , pp. 239-252
    • Metz, S.A.1
  • 15
    • 0023657246 scopus 로고
    • Accumulation of lysophosphatidylinositol in RAW 264.7 macrophage tumor cells stimulated by lipid A precursors
    • Zoeller RA, Wightman PD, Anderson MS, Raetz CR 1987 Accumulation of lysophosphatidylinositol in RAW 264.7 macrophage tumor cells stimulated by lipid A precursors. J Biol Chem 262: 17212-17220
    • (1987) J Biol Chem , vol.262 , pp. 17212-17220
    • Zoeller, R.A.1    Wightman, P.D.2    Anderson, M.S.3    Raetz, C.R.4
  • 16
    • 0023818187 scopus 로고
    • Lysophosphatidylinositol: A potential mediator of 1,25-dihydroxyvitamin D-induced increments in he-patocyte cytosolic calcium
    • Baran DT, Kelly AM 1988 Lysophosphatidylinositol: a potential mediator of 1,25-dihydroxyvitamin D-induced increments in he-patocyte cytosolic calcium. Endocrinology 122:930-934
    • (1988) Endocrinology , vol.122 , pp. 930-934
    • Baran, D.T.1    Kelly, A.M.2
  • 17
    • 0027087301 scopus 로고
    • Phosphatidylinositol hydrolysis by phospholipase A2 and C activities in human peripheral blood neutrophils
    • Smith DM, Waite M 1992 Phosphatidylinositol hydrolysis by phospholipase A2 and C activities in human peripheral blood neutrophils. J Leukoc Biol 52:670-678
    • (1992) J Leukoc Biol , vol.52 , pp. 670-678
    • Smith, D.M.1    Waite, M.2
  • 18
    • 0028202831 scopus 로고
    • Elevated levels and mitogenic activity of lysophosphatidylinositol in k-ras-transformed epithelial cells
    • Falasca M, Corda D 1994 Elevated levels and mitogenic activity of lysophosphatidylinositol in k-ras-transformed epithelial cells. Eur J Biochem 221:383-389
    • (1994) Eur J Biochem , vol.221 , pp. 383-389
    • Falasca, M.1    Corda, D.2
  • 20
    • 0034015340 scopus 로고    scopus 로고
    • Evaluation of plasma lysophospholipids for diagnostic significance using elec-trospray ionization mass spectrometry (ESI-MS) analyses
    • Xiao Y, Chen Y, Kennedy AW, Belinson J, Xu Y 2000 Evaluation of plasma lysophospholipids for diagnostic significance using elec-trospray ionization mass spectrometry (ESI-MS) analyses. Ann NY Acad Sci 905:242-259
    • (2000) Ann NY Acad Sci , vol.905 , pp. 242-259
    • Xiao, Y.1    Chen, Y.2    Kennedy, A.W.3    Belinson, J.4    Xu, Y.5
  • 21
    • 0034785693 scopus 로고    scopus 로고
    • Fatty acid composition of lysophosphatidic acid and lyso- phosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases
    • Shen Z, Wu M, Elson P, Kennedy AW, Belinson J, Casey G, Xu Y 2001 Fatty acid composition of lysophosphatidic acid and lyso- phosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases. Gynecol Oncol 83:25-30
    • (2001) Gynecol Oncol , vol.83 , pp. 25-30
    • Shen, Z.1    Wu, M.2    Elson, P.3    Kennedy, A.W.4    Belinson, J.5    Casey, G.6    Xu, Y.7
  • 23
    • 0036303682 scopus 로고    scopus 로고
    • A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cul tures
    • Blondeau N, Lauritzen I, Widmann C, Lazdunski M, Heurteaux C 2002 A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cul tures. J Cereb Blood Flow Metab 22:821-834
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 821-834
    • Blondeau, N.1    Lauritzen, I.2    Widmann, C.3    Lazdunski, M.4    Heurteaux, C.5
  • 24
    • 0034615923 scopus 로고    scopus 로고
    • Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK
    • Maingret F, Patel AJ, Lesage F, Lazdunski M, Honore E 2000 Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK. J Biol Chem 275:10128-10133
    • (2000) J Biol Chem , vol.275 , pp. 10128-10133
    • Maingret, F.1    Patel, A.J.2    Lesage, F.3    Lazdunski, M.4    Honore, E.5
  • 25
    • 0033524644 scopus 로고    scopus 로고
    • Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain
    • Sawzdargo M, Nguyen T, Lee DK, Lynch KR, Cheng R, Heng HH, George SR, O'Dowd BF 1999 Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain. Brain Res Mol Brain Res 64:193-198
    • (1999) Brain Res Mol Brain Res , vol.64 , pp. 193-198
    • Sawzdargo, M.1    Nguyen, T.2    Lee, D.K.3    Lynch, K.R.4    Cheng, R.5    Heng, H.H.6    George, S.R.7    O'Dowd, B.F.8
  • 28
    • 33947381686 scopus 로고    scopus 로고
    • The highly conserved DRY motif of class A G protein-coupled receptors: Beyond the ground state
    • Rovati GE, Capra V, Neubig RR 2007 The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol Pharmacol 71:959-964
    • (2007) Mol Pharmacol , vol.71 , pp. 959-964
    • Rovati, G.E.1    Capra, V.2    Neubig, R.R.3
  • 30
    • 33645323225 scopus 로고    scopus 로고
    • GPR55 as a new cannabinoid receptor: Still a long way to prove it
    • Petitet F, Donlan M, Michel A 2006 GPR55 as a new cannabinoid receptor: still a long way to prove it. Chem Biol Drug Des 67:252-253
    • (2006) Chem Biol Drug Des , vol.67 , pp. 252-253
    • Petitet, F.1    Donlan, M.2    Michel, A.3
  • 33
    • 56049101882 scopus 로고    scopus 로고
    • Ligand-binding architecture of human CB2 cannabinoid receptor: Evidence for receptor subtype-specific binding motif and modeling GPCR activation
    • Pei Y, Mercier RW, Anday JK, Thakur GA, Zvonok AM, Hurst D, Reggio PH, Janero DR, Makriyannis A 2008 Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation. Chem Biol 15:1207-1219
    • (2008) Chem Biol , vol.15 , pp. 1207-1219
    • Pei, Y.1    Mercier, R.W.2    Anday, J.K.3    Thakur, G.A.4    Zvonok, A.M.5    Hurst, D.6    Reggio, P.H.7    Janero, D.R.8    Makriyannis, A.9
  • 34
    • 27844505656 scopus 로고    scopus 로고
    • (-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahyd-rocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor
    • Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A 2005 (-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahyd-rocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor. Mol Pharmacol 68:1623-1635
    • (2005) Mol Pharmacol , vol.68 , pp. 1623-1635
    • Picone, R.P.1    Khanolkar, A.D.2    Xu, W.3    Ayotte, L.A.4    Thakur, G.A.5    Hurst, D.P.6    Abood, M.E.7    Reggio, P.H.8    Fournier, D.J.9    Makriyannis, A.10
  • 35
    • 79951515395 scopus 로고    scopus 로고
    • Lipid bi-layer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55
    • Kotsikorou E, Lynch DL, Abood ME, Reggio PH 2011 Lipid bi-layer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55. Chem Phys Lipids 164: 131-143
    • (2011) Chem Phys Lipids , vol.164 , pp. 131-143
    • Kotsikorou, E.1    Lynch, D.L.2    Abood, M.E.3    Reggio, P.H.4
  • 37
    • 77954334575 scopus 로고    scopus 로고
    • Endocannabinoid-like N-arachidonoyl serine is a novel pro-angio-genic mediator
    • Zhang X, Maor Y, Wang JF, Kunos G, Groopman JE 2010 Endocannabinoid-like N-arachidonoyl serine is a novel pro-angio-genic mediator. Br J Pharmacol 160:1583-1594
    • (2010) Br J Pharmacol , vol.160 , pp. 1583-1594
    • Zhang, X.1    Maor, Y.2    Wang, J.F.3    Kunos, G.4    Groopman, J.E.5
  • 39
    • 58249109364 scopus 로고    scopus 로고
    • The GPR55 ligand L-a-lysophosphatidylinositol promotes RhoA-dependent Ca2 + signaling and NFAT activation
    • Henstridge CM, Balenga NA, Ford LA, Ross RA, Waldhoer M, Irving AJ 2009 The GPR55 ligand L-a-lysophosphatidylinositol promotes RhoA-dependent Ca2 + signaling and NFAT activation. FASEB J 23:183-193
    • (2009) FASEB J , vol.23 , pp. 183-193
    • Henstridge, C.M.1    Balenga, N.A.2    Ford, L.A.3    Ross, R.A.4    Waldhoer, M.5    Irving, A.J.6
  • 44
    • 80054974781 scopus 로고    scopus 로고
    • The GPCR-associated sorting protein 1 regulates ligand-induced downregulation of GPR55
    • 30 June 2011, 10.1111/j.1476-5381.2011.01562.x
    • Kargl J, Balenga N, Platzer W, Martini L, Whistler J, Waldhoer M 30 June 2011 The GPCR-associated sorting protein 1 regulates ligand-induced downregulation of GPR55. Br J Pharmacol 10.1111/j.1476-5381.2011.01562.x
    • Br J Pharmacol
    • Kargl, J.1    Balenga, N.2    Platzer, W.3    Martini, L.4    Whistler, J.5    Waldhoer, M.6
  • 45
    • 35148832669 scopus 로고    scopus 로고
    • Regulation of [Ca2+]i oscillations in mouse pancreatic islets by adrenergic agonists
    • Baltrusch S, Lenzen S 2007 Regulation of [Ca2+]i oscillations in mouse pancreatic islets by adrenergic agonists. Biochem Biophys Res Commun 363:1038-1043
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 1038-1043
    • Baltrusch, S.1    Lenzen, S.2
  • 46
    • 0031883978 scopus 로고    scopus 로고
    • Cytosolic calcium oscillations and insulin release in pancreatic islets of Langerhans
    • Soria B, Martin F 1998 Cytosolic calcium oscillations and insulin release in pancreatic islets of Langerhans. Diabetes Metab 24: 37-40
    • (1998) Diabetes Metab , vol.24 , pp. 37-40
    • Soria, B.1    Martin, F.2
  • 50
    • 77952954092 scopus 로고    scopus 로고
    • Lysophosphatidylinositol induces rapid phosphorylation of p38 mitogen-activated protein kinase and activating transcription factor 2 in HEK293 cells expressing GPR55 and IM-9 lymphoblas-toid cells
    • Oka S, Kimura S, Toshida T, Ota R, Yamashita A, Sugiura T 2010 Lysophosphatidylinositol induces rapid phosphorylation of p38 mitogen-activated protein kinase and activating transcription factor 2 in HEK293 cells expressing GPR55 and IM-9 lymphoblas-toid cells. J Biochem 147:671-678
    • (2010) J Biochem , vol.147 , pp. 671-678
    • Oka, S.1    Kimura, S.2    Toshida, T.3    Ota, R.4    Yamashita, A.5    Sugiura, T.6
  • 52
    • 78651383853 scopus 로고    scopus 로고
    • The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation
    • Pineiro R, Maffucci T, Falasca M 2011 The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. Oncogene 30:142-152
    • (2011) Oncogene , vol.30 , pp. 142-152
    • Pineiro, R.1    Maffucci, T.2    Falasca, M.3
  • 53
    • 46249108439 scopus 로고    scopus 로고
    • Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression
    • Waldeck-Weiermair M, Zoratti C, Osibow K, Balenga N, Goess-nitzer E, Waldhoer M, Malli R, Graier WF 2008 Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression. J Cell Sci 121:1704-1717
    • (2008) J Cell Sci , vol.121 , pp. 1704-1717
    • Waldeck-Weiermair, M.1    Zoratti, C.2    Osibow, K.3    Balenga, N.4    Goess-Nitzer, E.5    Waldhoer, M.6    Malli, R.7    Graier, W.F.8
  • 54
    • 51349141952 scopus 로고    scopus 로고
    • Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
    • Katona I, Freund TF 2008 Endocannabinoid signaling as a synaptic circuit breaker in neurological disease. Nat Med 14:923-930
    • (2008) Nat Med , vol.14 , pp. 923-930
    • Katona, I.1    Freund, T.F.2
  • 55
    • 77957299242 scopus 로고    scopus 로고
    • Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes
    • Navarrete M, Araque A 2010 Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes. Neuron 68: 113-126
    • (2010) Neuron , vol.68 , pp. 113-126
    • Navarrete, M.1    Araque, A.2
  • 56
    • 77954406421 scopus 로고    scopus 로고
    • Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas
    • Stella N 2010 Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas. Glia 58:1017-1030
    • (2010) Glia , vol.58 , pp. 1017-1030
    • Stella, N.1
  • 57
    • 0034948614 scopus 로고    scopus 로고
    • Evidence for a new G protein-coupled cannabinoid receptor in mouse brain
    • Breivogel CS, Griffin G, Di Marzo V, Martin BR 2001 Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. Mol Pharmacol 60:155-163
    • (2001) Mol Pharmacol , vol.60 , pp. 155-163
    • Breivogel, C.S.1    Griffin, G.2    di Marzo, V.3    Martin, B.R.4
  • 58
    • 0042318499 scopus 로고    scopus 로고
    • Endocannabinoids contribute to short-term but not long-term mGluR-induced depression in the hippocampus
    • Rouach N, Nicoll RA 2003 Endocannabinoids contribute to short-term but not long-term mGluR-induced depression in the hippocampus. Eur J Neurosci 18:1017-1020
    • (2003) Eur J Neurosci , vol.18 , pp. 1017-1020
    • Rouach, N.1    Nicoll, R.A.2
  • 59
    • 0035801320 scopus 로고    scopus 로고
    • Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
    • Hajos N, Ledent C, Freund TF 2001 Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience United States 106:1-4
    • (2001) Neuroscience United States , vol.106 , pp. 1-4
    • Hajos, N.1    Ledent, C.2    Freund, T.F.3
  • 60
    • 0037207070 scopus 로고    scopus 로고
    • Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition
    • Hajos N, Freund TF 2002 Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition. Chem Phys Lipids 121:73-82
    • (2002) Chem Phys Lipids , vol.121 , pp. 73-82
    • Hajos, N.1    Freund, T.F.2
  • 61
    • 0345118964 scopus 로고    scopus 로고
    • Cannabinoids modulate neuronal firing in the rat basolateral amygdala: Evidence for CB1- and non-CB1-mediated actions
    • Pistis M, Perra S, Pillolla G, Melis M, Gessa GL, Muntoni AL 2004 Cannabinoids modulate neuronal firing in the rat basolateral amygdala: evidence for CB1- and non-CB1-mediated actions. Neuropharmacology 46:115-125
    • (2004) Neuropharmacology , vol.46 , pp. 115-125
    • Pistis, M.1    Perra, S.2    Pillolla, G.3    Melis, M.4    Gessa, G.L.5    Muntoni, A.L.6
  • 64
    • 54049144180 scopus 로고    scopus 로고
    • Wiring and firing neuronal networks: Endocannabinoids take center stage
    • Harkany T, Mackie K, Doherty P 2008 Wiring and firing neuronal networks: endocannabinoids take center stage. Curr Opin Neuro-biol 18:338-345
    • (2008) Curr Opin Neuro-biol , vol.18 , pp. 338-345
    • Harkany, T.1    Mackie, K.2    Doherty, P.3
  • 66
    • 77956420080 scopus 로고    scopus 로고
    • Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections
    • Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC 2010 Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci 32:693-706
    • (2010) Eur J Neurosci , vol.32 , pp. 693-706
    • Wu, C.S.1    Zhu, J.2    Wager-Miller, J.3    Wang, S.4    O'Leary, D.5    Monory, K.6    Lutz, B.7    Mackie, K.8    Lu, H.C.9
  • 67
    • 79954752203 scopus 로고    scopus 로고
    • A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells
    • Chiba T, Ueno S, Obara Y, Nakahata N 2011 A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. J Pharm Pharmacol 63:636-647
    • (2011) J Pharm Pharmacol , vol.63 , pp. 636-647
    • Chiba, T.1    Ueno, S.2    Obara, Y.3    Nakahata, N.4
  • 69
    • 79960330437 scopus 로고    scopus 로고
    • The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55
    • Schuelert N, McDougall JJ 2011 The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. Neurosci Lett 500: 72-76
    • (2011) Neurosci Lett , vol.500 , pp. 72-76
    • Schuelert, N.1    McDougall, J.J.2
  • 70
    • 22044454462 scopus 로고    scopus 로고
    • The effects of A9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide
    • O'Sullivan SE, Kendall DA, Randall MD 2005 The effects of A9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide. Br J Pharmacol 145:514-526
    • (2005) Br J Pharmacol , vol.145 , pp. 514-526
    • O'Sullivan, S.E.1    Kendall, D.A.2    Randall, M.D.3
  • 73
    • 0038561226 scopus 로고    scopus 로고
    • Vasodilator actions of abnormal-canna-bidiol in rat isolated small mesenteric artery
    • Ho WS, Hiley CR 2003 Vasodilator actions of abnormal-canna-bidiol in rat isolated small mesenteric artery. Br J Pharmacol 138: 1320-1332
    • (2003) Br J Pharmacol , vol.138 , pp. 1320-1332
    • Ho, W.S.1    Hiley, C.R.2
  • 74
    • 0032924113 scopus 로고    scopus 로고
    • Mesenteric vasodilation mediated by endothelial anandamide receptors
    • Wagner JA, Varga K, Jarai Z, Kunos G 1999 Mesenteric vasodilation mediated by endothelial anandamide receptors. Hypertension 33:429-434
    • (1999) Hypertension , vol.33 , pp. 429-434
    • Wagner, J.A.1    Varga, K.2    Jarai, Z.3    Kunos, G.4
  • 76
    • 77249118258 scopus 로고    scopus 로고
    • Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries
    • Daly CJ, Ross RA, Whyte J, Henstridge CM, Irving AJ, McGrath JC 2010 Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br J Pharmacol 159:787-796
    • (2010) Br J Pharmacol , vol.159 , pp. 787-796
    • Daly, C.J.1    Ross, R.A.2    Whyte, J.3    Henstridge, C.M.4    Irving, A.J.5    McGrath, J.C.6
  • 77
    • 0024522316 scopus 로고
    • Bradykinin-induced activation of phospholipase A2 is independent of the activation of poly-phosphoinositide-hydrolyzing phospholipase C
    • Kaya H, Patton GM, Hong SL 1989 Bradykinin-induced activation of phospholipase A2 is independent of the activation of poly-phosphoinositide-hydrolyzing phospholipase C. J Biol Chem 264: 4972-4977
    • (1989) J Biol Chem , vol.264 , pp. 4972-4977
    • Kaya, H.1    Patton, G.M.2    Hong, S.L.3
  • 79
    • 77956018359 scopus 로고    scopus 로고
    • GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells
    • Bondarenko A, Waldeck-Weiermair M, Naghdi S, Poteser M, Malli R, Graier WF 2010 GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells. Br J Pharmacol 161:308-320
    • (2010) Br J Pharmacol , vol.161 , pp. 308-320
    • Bondarenko, A.1    Waldeck-Weiermair, M.2    Naghdi, S.3    Poteser, M.4    Malli, R.5    Graier, W.F.6
  • 80
    • 78751650607 scopus 로고    scopus 로고
    • The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K+ channels in endothelial cells
    • Bondarenko AI, Malli R, Graier WF 2011 The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K+ channels in endothelial cells. Pflugers Arch 461:177-189
    • (2011) Pflugers Arch , vol.461 , pp. 177-189
    • Bondarenko, A.I.1    Malli, R.2    Graier, W.F.3
  • 81
    • 80051552586 scopus 로고    scopus 로고
    • The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca(2 +)-activated K (+) channels
    • Bondarenko AI, Malli R, Graier WF 2011 The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca(2 +)-activated K (+) channels. Pflugers Arch 462:245-255
    • (2011) Pflugers Arch , vol.462 , pp. 245-255
    • Bondarenko, A.I.1    Malli, R.2    Graier, W.F.3
  • 82
    • 79952198989 scopus 로고    scopus 로고
    • Is lipid signaling through cannabinoid 2 receptors part of a protective system?
    • Pacher P, Mechoulam R 2011 Is lipid signaling through cannabinoid 2 receptors part of a protective system? Prog Lipid Res 50: 193-211
    • (2011) Prog Lipid Res , vol.50 , pp. 193-211
    • Pacher, P.1    Mechoulam, R.2
  • 83
    • 77954177664 scopus 로고    scopus 로고
    • Cannabinoids and the immune system: An overview
    • Tanasescu R, Constantinescu CS 2010 Cannabinoids and the immune system: an overview. Immunobiology 215:588-597
    • (2010) Immunobiology , vol.215 , pp. 588-597
    • Tanasescu, R.1    Constantinescu, C.S.2
  • 84
    • 67651183650 scopus 로고    scopus 로고
    • Endogenous cannabinoids and neutrophil chemotaxis
    • McHugh D, Ross RA 2009 Endogenous cannabinoids and neutrophil chemotaxis. Vitam Horm 81:337-365
    • (2009) Vitam Horm , vol.81 , pp. 337-365
    • McHugh, D.1    Ross, R.A.2
  • 85
    • 77952731052 scopus 로고    scopus 로고
    • N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor
    • McHugh D, Hu SS, Rimmerman N, Juknat A, Vogel Z, Walker JM, Bradshaw HB 2010 N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor. BMC Neurosci 11:44
    • (2010) BMC Neurosci , vol.11 , pp. 44
    • McHugh, D.1    Hu, S.S.2    Rimmerman, N.3    Juknat, A.4    Vogel, Z.5    Walker, J.M.6    Bradshaw, H.B.7
  • 88
    • 53849106456 scopus 로고    scopus 로고
    • Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption
    • Sims NA, Gooi JH 2008 Bone remodeling: multiple cellular interactions required for coupling of bone formation and resorption. Semin Cell Dev Biol 19:444-451
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 444-451
    • Sims, N.A.1    Gooi, J.H.2
  • 90
    • 77950653576 scopus 로고    scopus 로고
    • Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists
    • Pertwee RG 2010 Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists. Curr Med Chem 17:1360-1381
    • (2010) Curr Med Chem , vol.17 , pp. 1360-1381
    • Pertwee, R.G.1
  • 91
    • 0142166330 scopus 로고    scopus 로고
    • Cannabinoids: Potential anticancer agents
    • Guzmán M 2003 Cannabinoids: potential anticancer agents. Nat Rev Cancer 3:745-755
    • (2003) Nat Rev Cancer , vol.3 , pp. 745-755
    • Guzmán, M.1
  • 97
    • 0035869447 scopus 로고    scopus 로고
    • Electrospray ionization mass spectrometry analysis of lysophospholipids in human ascitic fluids: Comparison of the lysophospholipid contents in malignant vs nonmalignant ascitic fluids
    • Xiao YJ, Schwartz B, Washington M, Kennedy A, Webster K, Belinson J, Xu Y 2001 Electrospray ionization mass spectrometry analysis of lysophospholipids in human ascitic fluids: comparison of the lysophospholipid contents in malignant vs nonmalignant ascitic fluids. Anal Biochem 290:302-313
    • (2001) Anal Biochem , vol.290 , pp. 302-313
    • Xiao, Y.J.1    Schwartz, B.2    Washington, M.3    Kennedy, A.4    Webster, K.5    Belinson, J.6    Xu, Y.7
  • 98
    • 58149138962 scopus 로고    scopus 로고
    • 2-Arachidonoyl-sn-glycero-3-phosphoinositol: A possible natural ligand for GPR55
    • Oka S, Toshida T, Maruyama K, Nakajima K, Yamashita A, Sugiura T 2009 2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55. J Biochem 145:13-20
    • (2009) Biochem , vol.145 , pp. 13-20
    • Oka, S.1    Toshida, T.2    Maruyama, K.3    Nakajima, K.4    Yamashita, A.5    Sugiura, T.6
  • 99
    • 0032493062 scopus 로고    scopus 로고
    • Release of the mitogen lysophosphatidylinositol from H-Ras-trans-formed fibroblasts; a possible mechanism of autocrine control of cell proliferation
    • Falasca M, Iurisci C, Carvelli A, Sacchetti A, Corda D 1998 Release of the mitogen lysophosphatidylinositol from H-Ras-trans-formed fibroblasts; a possible mechanism of autocrine control of cell proliferation. Oncogene 16:2357-2365
    • (1998) Oncogene , vol.16 , pp. 2357-2365
    • Falasca, M.1    Iurisci, C.2    Carvelli, A.3    Sacchetti, A.4    Corda, D.5
  • 101
    • 78650845707 scopus 로고    scopus 로고
    • G protein-coupled receptors: Novel targets for drug discovery in cancer
    • Lappano R, Maggiolini M 2011 G protein-coupled receptors: novel targets for drug discovery in cancer. Nat Rev Drug Discov 10:47-60
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 47-60
    • Lappano, R.1    Maggiolini, M.2
  • 107
    • 33845673559 scopus 로고    scopus 로고
    • Endocannabinoids and the control of energy balance
    • Matias I, Di Marzo V 2007 Endocannabinoids and the control of energy balance. Trends Endocrinol Metab 18:27-37
    • (2007) Trends Endocrinol Metab , vol.18 , pp. 27-37
    • Matias, I.1    di Marzo, V.2
  • 110
    • 78650141494 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature
    • Chun J, Hla T, Lynch KR, Spiegel S, Moolenaar WH 2010 International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature. Pharmacol Rev 62: 579-587
    • (2010) Pharmacol Rev , vol.62 , pp. 579-587
    • Chun, J.1    Hla, T.2    Lynch, K.R.3    Spiegel, S.4    Moolenaar, W.H.5
  • 111
    • 46949104885 scopus 로고    scopus 로고
    • Inside-out signaling of sphingosine-1-phosphate: Therapeutic targets
    • Takabe K, Paugh SW, Milstien S, Spiegel S 2008 "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol Rev 60:181-195
    • (2008) Pharmacol Rev , vol.60 , pp. 181-195
    • Takabe, K.1    Paugh, S.W.2    Milstien, S.3    Spiegel, S.4
  • 113
    • 77949504534 scopus 로고    scopus 로고
    • Lysophosphatidic acid production and action: Critical new players in breast cancer initiation and progression
    • Panupinthu N, Lee HY, Mills GB 2010 Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression. Br J Cancer 102:941-946
    • (2010) Br J Cancer , vol.102 , pp. 941-946
    • Panupinthu, N.1    Lee, H.Y.2    Mills, G.B.3
  • 114
    • 77949492248 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) receptors: Signaling properties and disease relevance
    • Lin ME, Herr DR, Chun J 2010 Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance. Prostaglandins Other Lipid Mediat 91:130-138
    • (2010) Prostaglandins Other Lipid Mediat , vol.91 , pp. 130-138
    • Lin, M.E.1    Herr, D.R.2    Chun, J.3
  • 116
    • 79955716430 scopus 로고    scopus 로고
    • L-a-Lysophosphatidylinositol meets GPR55: A deadly relationship
    • Ross RA 2011 L-a-Lysophosphatidylinositol meets GPR55: a deadly relationship. Trends Pharmacol Sci 32:265-269
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 265-269
    • Ross, R.A.1
  • 119
    • 1542704056 scopus 로고    scopus 로고
    • GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: Possible role in neuroimmune function
    • Moore DJ, Murdock PR, Watson JM, Faull RL, Waldvogel HJ, Szekeres PG, Wilson S, Freeman KB, Emson PC 2003 GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function. Brain Res Mol Brain Res 118:10-23
    • (2003) Brain Res Mol Brain Res , vol.118 , pp. 10-23
    • Moore, D.J.1    Murdock, P.R.2    Watson, J.M.3    Faull, R.L.4    Waldvogel, H.J.5    Szekeres, P.G.6    Wilson, S.7    Freeman, K.B.8    Emson, P.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.