Suppressor of cytokine signaling-1 (SOCS1) inhibits lymphocyte recruitment into the retina and protects SOCS1 transgenic rats and mice from ocular inflammation

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 9, 2011, Pages 6978-6986

  Yu, Cheng Rong ^a   Mahdi, Rashid R ^a   Oh, Hyun Mee ^a   Amadi Obi, Ahjoku ^a   Levy Clarke, Grace ^a   Burton, Jenna ^a   Eseonu, Amarachi ^b   Lee, YongJun ^a   Chan, Chi Chao ^a   Egwuagu, Charles E ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b HARVARD COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CXCL9 CHEMOKINE; GAMMA INTERFERON ANTIBODY; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 17; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; RECOMBINANT INTERLEUKIN 2; RETINOID BINDING PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; THYMUS AND ACTIVATION REGULATED CHEMOKINE; CYTOKINE; EYE PROTEIN; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; INTERSTITIAL RETINOL-BINDING PROTEIN; RETINOL BINDING PROTEIN; SOCS1 PROTEIN, MOUSE; SOCS1 PROTEIN, RAT; SUPPRESSOR OF CYTOKINE SIGNALING;

ACTIVE IMMUNIZATION; ADOPTIVE TRANSFER; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL EXPANSION; CELL ISOLATION; CELL PROTECTION; CLINICAL ARTICLE; CONTROLLED STUDY; EXPERIMENTAL AUTOIMMUNE UVEORETINITIS; FEMALE; FLOW CYTOMETRY; HISTOLOGY; HUMAN; HUMAN CELL; LYMPH NODE CELL; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY; SCLERITIS; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TRANSGENIC MOUSE; TRANSGENIC RAT; UVEITIS; UVEORETINITIS; WESTERN BLOTTING; ANIMAL; AUTOIMMUNE DISEASE; C57BL MOUSE; CELL MOTION; FISCHER 344 RAT; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PHYSIOLOGY; RETINITIS;

ADOPTIVE TRANSFER; ADULT; AGED, 80 AND OVER; ANIMALS; APOPTOSIS; AUTOIMMUNE DISEASES; BLOTTING, WESTERN; CELL MOVEMENT; CYTOKINES; EYE PROTEINS; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE AGED; RATS; RATS, INBRED F344; RATS, TRANSGENIC; RETINITIS; RETINOL-BINDING PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCLERITIS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; T-LYMPHOCYTES; UVEITIS; YOUNG ADULT;

EID: 80054933795     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7688     Document Type: Article

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