Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens

Developmental Biology

Volumn 210, Issue 1, 1999, Pages 44-55

  Wenmei, Li ^a   Nagineni, Chandrasekharam N ^a   Efiok, Bassey ^b   Chepelinsky, Ana B ^c   Egwuagu, Charles E ^a,c  

^a Laboratory of Immunology   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c NATIONAL EYE INSTITUTE   (United States)

Author keywords

ICSBP; IFN ; IRF 1; IRF 2; Lens differentiation; LSIRF Pip; STAT1

Indexed keywords

CYTOPLASM PROTEIN; GAMMA INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; STAT1 PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CONTROLLED STUDY; CYTOPLASM; ELECTROPHORETIC MOBILITY; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LENS; LENS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENE; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS; VERTEBRATA;

EID: 0033151967     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9267     Document Type: Article

References (46)

1. Alonso, S., Minty, A., Bourlet, Y., and Buckingham, M. (1986). Comparison of three actin-coding sequences in the mouse: Evolutionary relationships between the actin genes of warm blooded vertebrates. J. Mol. Evol. 23, 11-22.
2. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Stuhl, K. (1995). "Current Protocols in Molecular Biology." Wiley, New York.
3. Boehm, U., Klamp, T., and Howard, J. C. (1997). Cellular responses to interferon-γ. Annu. Rev. Immunol. 15, 749-795.
4. Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
5. Darnell, J. E., Jr. (1997). STATs and gene regulation. Science 277, 1630-1635.
6. Decker, T., Kovarik, P., and Meinke, A. (1997). GAS elements: A few nucleotides with a major impact on cytokine-induced gene expression. J. Interferon Cytol. Res. 17, 121-134.
7. Drew, P. D., Franzoso, G., Becker, K. G., Bours, V., Carlson, L. M., Siebenlist, U., and Ozato, K. (1995a). NF kappa B and interferon regulatory factor 1 physically interact and synergistically induce major histocompatibility class I gene expression. J. Interferon Cytol. Res. 15, 1037-1045
8. Drew, P. D., Franzoso, G., Carlson, L. M., Biddison, W. E., SiebenList, U., and Ozato, K. (1995b). Interferon regulatory factor-2 physically interacts with NF-kappa B in vitro and inhibits NF-kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells. J. Neuroimmunol. 63, 157-62.
9. Driggers, P. H., Ennist, D. L., Gleason, S. L., Mak, W.-H., Marks, M. S., Levi, B.-Z., Flanagan, J. R., Appella, E., and Ozato, K. (1990). An interferon γ-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes. Proc. Natl. Acad. Sci. USA 87, 3743-3747.
10. Egwuagu, C. E., Sztein, J., Chan, C. C., Reid, W., Mahdi, R., Nussenblatt, R. B., and Chepelinsky, A. B. (1994a). Ectopic expression of gamma interferon in the eyes of transgenic mice induces ocular pathology and MHC class II gene expression. Invest. Ophthalmol. Visual Sci. 35, 332-341.
11. Egwuagu, C. E., Sztein, J., Chan, C. C., Mahdi, R., Nussenblatt, R. B., and Chepelinsky, A. B. (1994b). γInterferon expression disrupts lens and retinal differentiation in transgenic mice. Dev. Biol. 166, 557-568.
12. Egwuagu, C. E., Sztein, J., Mahdi, R. M., Li, W., Chan, C. C., Smith, J. A., Charukamnoetkanok, P., and Chepelinsky, A. B. (1999). Interferon-γ (IFNγ) increases the severity and accelerates the onset of experimental autoimmune uveitis in transgenic rats. J. Immunol. 162, 510-517.
13. Eisenbeis, C. F., Singh, H., and Storb, U. (1995). Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator. Genes Dev. 9, 1377-1387.
14. cdc2, and H1-kinase activity in terminally differentiating lens fiber cells. Dev. Biol. 169, 185-194.
15. Gao, C. Y., Zakeri, Z., Zhu, Y., He, H., and Zelenka, P. S. (1997). Expression of cdk5, p35, and cdk5-associated kinases activity in the developing rat lens. Dev. Genet. 20, 267-275.
16. Harada, H., Fujita, T., Miyamoto, M., Kimura, Y., Maruyama, M., Furia, A., Miyata, T., and Taniguchi, T. (1989). Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58, 729-739.
17. Harada, H., Willison, K., Sakakibara, J., Miyamoto, M., Fujita, T., and Taniguchi, T. (1990). Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated. Cell 63, 303-312.
18. Holtschke, E., Lohler, J., Kanno, Y., Fehr, T., Giese, N., Rosenbauer, F., Lou, J., Knobeloch, K., Gabriele, L., Waring, J. F., Bachmann, M. F., Zinkernagel, R. M., Morse, H. C., III, Ozato, K., and Horak, I.. (1996). Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation in the ICSBP gene. Cell 87, 307-317.
19. Kalvakolanu, D. V., and Borden, E. C. (1996). An overview of the interferon system: Signal transduction and mechanisms of action. Cancer Invest. 14, 25-53.
20. Kanno, Y., Kozak, C. A., Schindler, C., Driggers, P. H., Ennist, D. L., Gleason, S. L., Darnell, J. E., Jr., and Ozato, K. (1993). The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3α subunit (or similar) molecule binds. Mol. Cell. Biol. 3, 3951-3963.
21. Lang, R. A., and Bishop, M. J. (1993). Macrophages are required for cell death and tissue remodeling in the developing mouse eye. Cell 74, 453-452.
22. Matsuyama, T., Grossman, A., Mittrucker, H.-W., Siderovski, D. P., Kiefer, F., Kawakami, T., Richardson, C. D., Taniguchi, T., Yoshinaga, S. K., and Mak, T. W. (1995). Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE). Nucleic Acids Res. 23, 2127-2136.
23. McAvoy, J. W. (1981). Developmental biology of the lens. In "Mechanisms of Cataract Formation in the Human Lens" (G. Duncan, Ed.), pp. 7-46. Academic Press, New York.
24. Mittrucker, H. W., Matsuyama, T., Grossman, A., Kundig, T. M., Potter, J., Shahinian, A., Wakeham, A., Patterson, B., Ohashi, P. S., and Mak, T. W. (1997). Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275, 540-543.
25. Miyamoto, M., Fujita, T., Kimura, Y., Maruyama, M., Harada, H., Sudo, Y., Miyata, T., and Taniguchi, T. (1988). Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to the IFN-beta gene regulatory elements. Cell 54, 903-913.
26. Moore, P. S., Boshoff, C., Weiss, R. A., and Chang, Y. (1996). Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 274, 1739-1744.
27. Nelson, N., Kanno, Y., Hong, C., Cantursi, C., Fujita, T., Fowlkes, B. J., O'Connell, E., Hu-Li, J., Paul, W. E., Jankovic, D., Sher, A. F., Coligan, J. E., Thorton, A., Appella, E., Yang, Y., and Ozato, K. (1996). Expression of IFN regulatory factor family proteins in lymphocytes. J. Immunol. 156, 3711-3720.
28. Nguyen, H., Hiscott, J., and Pitha, P. M. (1997). The growing family of interferon regulatory factors. Cytokine Growth Factor Rev. 8, 293-312.
29. Ohtaka-Maruyama, C., Hanaoka, F., and Chepelinsky, A. B. (1998). A novel alternative spliced variant of the transcription factor AP2alpha is expressed in the murine ocular lens. Dev. Biol. 202, 125-135.
30. Piatigorsky, J. (1981). Lens differentiation in vertebrates: A review of cellular and molecular features. Differentiation 19, 134-153.
31. Pine, R., Decker, T., Kessler, D. S., Levy, D. E., and Darnell, J. E., Jr. (1990). Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to promoters of both interferon- and interferon-stimulated genes but is not a primary transcriptional activator. Mol. Cell. Biol. 10, 2448-2457.
32. Politis, A. D., Ozato, K., Coligan, J. E., and Vogel, S. N. (1994). Regulation of IFNγ-induced nuclear expression of IFN consensus sequence binding protein in murine macrophages. J. Immunol. 152, 2270-2278.
33. Sabath, D. E., Broome, H. E., and Prystowsky, M. B. (1990). Glyceraldehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte. Gene 91, 185-191.
34. Saunders, N., Dahler, A., Jones, S., Smith, R., and Jetten, A. (1996). Interferon-γ as a regulator of squamous differentiation. J. Dermatol. Sci. 13, 98-106.
35. Saunders, N. A., and Jetter, A. M. (1994). Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon-γ. J. Biol. Chem. 269, 2016-2022.
36. Sax, C. M., Dziedzic, D. C., Piatigorsky, J., and Reddan, J. R. (1995). Analysis of α-crystallin expression in cultured mouse and rabbit lens cells. Exp. Eye Res. 61, 125-127.
37. Schindler, C., and Darnell, J. E., Jr. (1995). Transcriptional responses to polypeptide ligands: The JAK-STAT pathway. Annu. Rev. Biochem. 64, 621-651.
38. Schreiber, E., Matthias, P., Muller, M. M., and Schaffner, W. (1989). Rapid detection of octamer binding proteins with mini-extracts, prepared from a small number of cells. Nucleic Acids Res. 17, 6419.
39. Taniguchi, T. (1997). Transcription factors IRF1 and IRF2: Linking the immune responses and tumor suppression. J. Cell. Physiol. 173, 128-130.
40. Taniguchi, T., Harada, H., and Lamphier, M. (1995). Regulation of the interferon system and cell growth by the IRF transcription factors. J. Cancer Res. Clin. Oncol. 121, 516-520.
41. Vaughan, P. S., van Wijnen, A. J., Stein, J. L., and Stein, G. S. (1997). Interferon regulatory factors: Growth control and histone gene regulation - It's not just interferon anymore. J. Mol. Med. 75, 348-359.
42. Vilcek, J., and Sen, G. C. (1996). Interferons and other cytokines. In "Fields Virology" (B. N. Fields et al., Eds.), pp. 375-398. Lippincott-Raven, Philadelphia.
43. Wistow, G. J., Shaughnessy, M. P., Lee, D. C., Hodin, J., and Zelenka, P. S. (1993). A macrophage migration inhibitory factor is expressed in the differentiating cells of the eye lens. Proc. Natl. Acad. Sci. USA 90, 1772-1775.
44. Yamada, T., Nakamura, T., Westphal, H., and Russell, P. (1990). Synthesis of α-crystallin by a cell line derived from the lens of a transgenic animal. Curr. Eye Res. 9, 31-37.
45. Yamagata, T., Nishida, J., Tanaka, T., Sakai, R., Mitani, K., YoShida, M., Taniguchi, T., Yazaki, Y., and Hirai, H. (1996). A novel interferon regulatory factor family transcription factor, ICSAT/ Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes. Mol. Cell. Biol. 16, 1283-1294.
46. Yoshida, K., Imaki, J., Koyama, Y., Harada, T., Shinmei, Y., Oishi, C., Matsushima-Hibiya, Y., Matsuda, A., Nishi, S., Matsuda, H., and Sakai, M. (1997). Differential expression of maf-1 and maf-2 genes in the developing rat lens. Invest. Ophthalmol Visual Sci. 38, 2679-83