-
1
-
-
22144438350
-
Rethinking the "diseases of affluence"paradigm: Global patterns of nutritional risks in relation to economic development
-
Ezzati M, Vander Hoorn S, Lawes CM, Leach R, James WP, Lopez AD, Rodgers A, Murray CJ 2005 Rethinking the "diseases of affluence"paradigm: global patterns of nutritional risks in relation to economic development. PLoS Med 2:e133
-
(2005)
PLoS Med
, vol.2
-
-
Ezzati, M.1
Vander Hoorn, S.2
Lawes, C.M.3
Leach, R.4
James, W.P.5
Lopez, A.D.6
Rodgers, A.7
Murray, C.J.8
-
2
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG 2000 Obesity as a medical problem. Nature 404:635-643 (Pubitemid 30205068)
-
(2000)
Nature
, vol.404
, Issue.6778
, pp. 635-643
-
-
Kopelman, P.G.1
-
3
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte Jr D, Seeley RJ, Baskin DG 2000 Central nervous system control of food intake. Nature 404:661-671 (Pubitemid 30205071)
-
(2000)
Nature
, vol.404
, Issue.6778
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
4
-
-
0035936764
-
Obesity and the regulation of energy balance
-
DOI 10.1016/S0092-8674(01)00240-9
-
Spiegelman BM, Flier JS 2001 Obesity and the regulation of energy balance. Cell 104:531-543 (Pubitemid 32201948)
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 531-543
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
5
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
DOI 10.1038/27376
-
Friedman JM, Halaas JL 1998 Leptin and the regulation of body weight in mammals. Nature 395:763-770 (Pubitemid 28485436)
-
(1998)
Nature
, vol.395
, Issue.6704
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
6
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
DOI 10.1038/nature02440
-
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, FerréP, Birnbaum MJ, Stuck BJ, Kahn BB 2004 AMPkinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428:569-574 (Pubitemid 38480541)
-
(2004)
Nature
, vol.428
, Issue.6982
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, H.3
Kim, Y.-B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
7
-
-
0037122766
-
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
-
DOI 10.1038/415339a
-
Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Müller C, Carling D, Kahn BB 2002 Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 415:339-343 (Pubitemid 34087557)
-
(2002)
Nature
, vol.415
, Issue.6869
, pp. 339-343
-
-
Minokoshi, Y.1
Kim, Y.-B.2
Peroni, O.D.3
Fryer, L.G.D.4
Muller, C.5
Carling, D.6
Kahn, B.B.7
-
8
-
-
1842405349
-
Leptin directly alters lipid partitioning in skeletal muscle
-
Muoio DM, Dohm GL, Fiedorek Jr FT, Tapscott EB, Coleman RA 1997 Leptin directly alters lipid partitioning in skeletal muscle. Diabetes 46:1360-1363 (Pubitemid 27315287)
-
(1997)
Diabetes
, vol.46
, Issue.8
, pp. 1360-1363
-
-
Muoio, D.M.1
Lynis, D.G.2
Fiedorek Jr., F.T.3
Tapscott, E.B.4
Coleman, R.A.5
-
9
-
-
1842582870
-
AMP-activated Protein Kinase Plays a Role in the Control of Food Intake
-
DOI 10.1074/jbc.C300557200
-
Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ 2004 AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem 279:12005-12008 (Pubitemid 38445761)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.13
, pp. 12005-12008
-
-
Andersson, U.1
Filipsson, K.2
Abbott, C.R.3
Woods, A.4
Smith, K.5
Bloom, S.R.6
Carling, D.7
Small, C.J.8
-
11
-
-
36849071229
-
Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake
-
DOI 10.1073/pnas.0708385104
-
Gao S, Kinzig KP, Aja S, Scott KA, Keung W, Kelly S, Strynadka K, Chohnan S, Smith WW, Tamashiro KL, Ladenheim EE, Ronnett GV, Tu Y, Birnbaum MJ, Lopaschuk GD, Moran TH 2007 Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake. Proc Natl Acad Sci USA 104:17358-17363 (Pubitemid 350219847)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.44
, pp. 17358-17363
-
-
Gao, S.1
Kinzig, K.P.2
Aja, S.3
Scott, K.A.4
Keung, W.5
Kelly, S.6
Strynadka, K.7
Chohnan, S.8
Smith, W.W.9
Tamashiro, K.L.K.10
Ladenheim, E.E.11
Ronnett, G.V.12
Tu, Y.13
Birnbaum, M.J.14
Lopaschuk, G.D.15
Moran, T.H.16
-
12
-
-
0037329602
-
Role of AMP-activated protein kinase in leptin-induced fatty acid oxidation in muscle
-
Minokoshi Y, Kahn BB 2003 Role of AMP-activated protein kinase in leptin-induced fatty acid oxidation in muscle. Biochem Soc Trans 31:196-201 (Pubitemid 36241427)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.1
, pp. 196-201
-
-
Minokoshi, Y.1
Kahn, B.B.2
-
13
-
-
26844446285
-
Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle
-
DOI 10.1073/pnas.0507300102
-
Cha SH, Hu Z, Chohnan S, Lane MD 2005 Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle. Proc Natl Acad Sci USA 102:14557-14562 (Pubitemid 41457096)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.41
, pp. 14557-14562
-
-
Cha, S.H.1
Hu, Z.2
Chohnan, S.3
Lane, M.D.4
-
16
-
-
0028116128
-
Acetyl-CoA carboxylase involvement in the rapid maturation of fatty acid oxidation in the newborn rabbit heart
-
Lopaschuk GD, Witters LA, Itoi T, Barr R, Barr A 1994 Acetyl-CoA carboxylase involvement in the rapid maturation of fatty acid oxidation in the newborn rabbit heart. J Biol Chem 269:25871-25878 (Pubitemid 24336288)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.41
, pp. 25871-25878
-
-
Lopaschuk, G.D.1
Witters, L.A.2
Itoi, T.3
Barr, R.4
Barr, A.5
-
17
-
-
0024210550
-
Determination of short-chain coenzyme A compounds by reversed-phase high-performance liquid chromatography
-
DOI 10.1016/S0076-6879(88)66012-5
-
King MT, Reiss PD, Cornell NW 1988 Determination of short-chain coenzyme A compounds by reversed-phase high-performance liquid chromatography. Methods Enzymol 166:70-79 (Pubitemid 19048579)
-
(1988)
Methods in Enzymology
, vol.166
, pp. 70-79
-
-
King, M.T.1
Reiss, P.D.2
Cornell, N.W.3
-
18
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch J, Lees M, Sloane Stanley GH 1957 A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226:497-509
-
(1957)
J Biol Chem
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
19
-
-
0022970190
-
Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells
-
Preiss J, Loomis CR, Bishop WR, Stein R, Niedel JE, Bell RM 1986 Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells. J Biol Chem 261:8597-8600 (Pubitemid 17205050)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.19
, pp. 8597-8600
-
-
Preiss, J.1
Loomis, C.R.2
Bishop, W.R.3
-
20
-
-
33646582664
-
Hypothalamic mTOR signaling regulates food intake
-
DOI 10.1126/science.1124147
-
Cota D, Proulx K, Smith KA, Kozma SC, Thomas G, Woods SC, Seeley RJ 2006 Hypothalamic mTOR signaling regulates food intake. Science 312:927-930 (Pubitemid 43727328)
-
(2006)
Science
, vol.312
, Issue.5775
, pp. 927-930
-
-
Cota, D.1
Proulx, K.2
Blake, S.K.A.3
Kozma, S.C.4
Thomas, G.5
Woods, S.C.6
Seeley, R.J.7
-
21
-
-
33745576798
-
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
-
DOI 10.1038/nn1731, PII N1731
-
Kim MS, Pak YK, Jang PG, Namkoong C, Choi YS, Won JC, Kim KS, Kim SW, Kim HS, Park JY, Kim YB, Lee KU 2006 Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis. Nat Neurosci 9:901-906 (Pubitemid 43980504)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.7
, pp. 901-906
-
-
Kim, M.-S.1
Pak, Y.K.2
Jang, P.-G.3
Namkoong, C.4
Choi, Y.-S.5
Won, J.-C.6
Kim, K.-S.7
Kim, S.-W.8
Kim, H.-S.9
Park, J.-Y.10
Kim, Y.-B.11
Lee, K.-U.12
-
22
-
-
70350203976
-
Central leptin action improves skeletal muscle AKT, AMPK, and PGC1α activation by hypothalamic PI3K-dependent mechanism
-
Roman EA, Reis D, Romanatto T, Maimoni D, Ferreira EA, Santos GA, Torsoni AS, Velloso LA, Torsoni MA 2010 Central leptin action improves skeletal muscle AKT, AMPK, and PGC1α activation by hypothalamic PI3K-dependent mechanism. Mol Cell Endocrinol 314:62-69
-
(2010)
Mol Cell Endocrinol
, vol.314
, pp. 62-69
-
-
Roman, E.A.1
Reis, D.2
Romanatto, T.3
Maimoni, D.4
Ferreira, E.A.5
Santos, G.A.6
Torsoni, A.S.7
Velloso, L.A.8
Torsoni, M.A.9
-
23
-
-
33745224043
-
Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle
-
DOI 10.1074/jbc.M512831200
-
Martin TL, Alquier T, Asakura K, Furukawa N, Preitner F, Kahn BB 2006 Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. J Biol Chem 281:18933-18941 (Pubitemid 44035396)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.28
, pp. 18933-18941
-
-
Martin, T.L.1
Alquier, T.2
Asakura, K.3
Furukawa, N.4
Preitner, F.5
Kahn, B.B.6
-
24
-
-
0037388560
-
Differential mechanisms and development of leptin resistance in A/J versus C57BL/6J mice during diet-induced obesity
-
DOI 10.1210/en.2002-220835
-
Prpic V, Watson PM, Frampton IC, Sabol MA, Jezek GE, Gettys TW 2003 Differential mechanisms and development of leptin resistance in A/J versus C57BL/6J mice during diet-induced obesity. Endocrinology 144:1155-1163 (Pubitemid 36428455)
-
(2003)
Endocrinology
, vol.144
, Issue.4
, pp. 1155-1163
-
-
Prpic, V.1
Watson, P.M.2
Frampton, I.C.3
Sabol, M.A.4
Jezek, G.E.5
Gettys, T.W.6
-
25
-
-
9244219587
-
Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
-
DOI 10.1210/en.2004-0726
-
Münzberg H, Flier JS, Bjørbaek C 2004 Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology 145:4880-4889 (Pubitemid 39551104)
-
(2004)
Endocrinology
, vol.145
, Issue.11
, pp. 4880-4889
-
-
Munzberg, H.1
Flier, J.S.2
Bjorbaek, C.3
-
26
-
-
37649003524
-
Regulation of hypothalamic malonyl-CoA by central glucose and leptin
-
Wolfgang MJ, Cha SH, Sidhaye A, Chohnan S, Cline G, Shulman GI, Lane MD 2007 Regulation of hypothalamic malonyl-CoA by central glucose and leptin. Proc Natl Acad Sci USA 104:19285-19290
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19285-19290
-
-
Wolfgang, M.J.1
Cha, S.H.2
Sidhaye, A.3
Chohnan, S.4
Cline, G.5
Shulman, G.I.6
Lane, M.D.7
-
28
-
-
0242300121
-
Hypothalamic malonyl-CoA as a mediator of feeding behavior
-
DOI 10.1073/pnas.1834402100
-
Hu Z, Cha SH, Chohnan S, Lane MD 2003 Hypothalamic malonyl- CoA as a mediator of feeding behavior. Proc Natl Acad Sci USA 100:12624-12629 (Pubitemid 37339949)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.22
, pp. 12624-12629
-
-
Hu, Z.1
Cha, S.H.2
Chohnan, S.3
Lane, M.D.4
-
29
-
-
0034733730
-
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
-
DOI 10.1126/science.288.5475.2379
-
Loftus TM, Jaworsky DE, Frehywot GL, Townsend CA, Ronnett GV, Lane MD, Kuhajda FP 2000 Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science 288:2379-2381 (Pubitemid 30448165)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2379-2381
-
-
Loftus, T.M.1
Jaworsky, D.E.2
Frehywot, C.L.3
Townsend, C.A.4
Ronnett, G.V.5
Daniel, L.M.6
Kuhajda, F.P.7
-
30
-
-
57349093501
-
Central exercise action increases the AMPK and mTOR response to leptin
-
Ropelle ER, Fernandes MF, Flores MB, Ueno M, Rocco S, Marin R, Cintra DE, Velloso LA, Franchini KG, Saad MJ, Carvalheira JB 2008 Central exercise action increases the AMPK and mTOR response to leptin. PLoS One 3:e3856
-
(2008)
PLoS One
, vol.3
-
-
Ropelle, E.R.1
Fernandes, M.F.2
Flores, M.B.3
Ueno, M.4
Rocco, S.5
Marin, R.6
Cintra, D.E.7
Velloso, L.A.8
Franchini, K.G.9
Saad, M.J.10
Carvalheira, J.B.11
-
31
-
-
40949150324
-
A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss
-
Ropelle ER, Pauli JR, Fernandes MF, Rocco SA, Marin RM, Morari J, Souza KK, Dias MM, Gomes-Marcondes MC, Gontijo JA, Franchini KG, Velloso LA, Saad MJ, Carvalheira JB 2008 A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss. Diabetes 57:594-605
-
(2008)
Diabetes
, vol.57
, pp. 594-605
-
-
Ropelle, E.R.1
Pauli, J.R.2
Fernandes, M.F.3
Rocco, S.A.4
Marin, R.M.5
Morari, J.6
Souza, K.K.7
Dias, M.M.8
Gomes-Marcondes, M.C.9
Gontijo, J.A.10
Franchini, K.G.11
Velloso, L.A.12
Saad, M.J.13
Carvalheira, J.B.14
-
32
-
-
34547651092
-
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
-
DOI 10.1172/JCI31516
-
Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, Clements M, Al-Qassab H, Heffron H, Xu AW, Speakman JR, Barsh GS, Viollet B, Vaulont S, Ashford ML, Carling D, Withers DJ 2007 AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J Clin Invest 117:2325-2336 (Pubitemid 47219577)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.8
, pp. 2325-2336
-
-
Claret, M.1
Smith, M.A.2
Batterham, R.L.3
Selman, C.4
Choudhury, A.I.5
Fryer, L.G.D.6
Clements, M.7
Al-Qassab, H.8
Heffron, H.9
Xu, A.W.10
Speakman, J.R.11
Barsh, G.S.12
Viollet, B.13
Vaulont, S.14
Ashford, M.L.J.15
Carling, D.16
Withers, D.J.17
-
33
-
-
3142677140
-
Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase
-
DOI 10.1038/nm1061
-
Kim MS, Park JY, Namkoong C, Jang PG, Ryu JW, Song HS, Yun JY, Namgoong IS, Ha J, Park IS, Lee IK, Viollet B, Youn JH, Lee HK, Lee KU 2004 Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med 10:727-733 (Pubitemid 38937638)
-
(2004)
Nature Medicine
, vol.10
, Issue.7
, pp. 727-733
-
-
Kim, M.-S.1
Park, J.-Y.2
Namkoong, C.3
Jang, P.-G.4
Ryu, J.-W.5
Song, H.-S.6
Yun, J.-Y.7
Namgoong, I.-S.8
Ha, J.9
Park, I.-S.10
Lee, I.-K.11
Viollet, B.12
Youn, J.H.13
Lee, H.-K.14
Lee, K.-U.15
-
34
-
-
0035950093
-
Intracellular signalling: Key enzyme in leptin-induced anorexia
-
Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers Jr MG, Schwartz MW 2001 Intracellular signalling. Key enzyme in leptininduced anorexia. Nature 413:794-795 (Pubitemid 33026839)
-
(2001)
Nature
, vol.413
, Issue.6858
, pp. 794-795
-
-
Niswender, K.D.1
Morton, G.J.2
Stearns, W.H.3
Rhodes, C.J.4
Myers Jr., M.G.5
Schwartz, M.W.6
-
35
-
-
33644665508
-
Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling
-
DOI 10.1152/ajpendo.00094.2005
-
Morrison CD, Morton GJ, Niswender KD, Gelling RW, Schwartz MW 2005 Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling. Am J Physiol Endocrinol Metab 289:E1051-E1057 (Pubitemid 43772054)
-
(2005)
American Journal of Physiology - Endocrinology and Metabolism
, vol.289
, Issue.6
-
-
Morrison, C.D.1
Morton, G.J.2
Niswender, K.D.3
Gelling, R.W.4
Schwartz, M.W.5
-
36
-
-
33646590947
-
Forkhead protein FoxO1 mediates Agrpdependent effects of leptin on food intake
-
Kitamura T, Feng Y, Kitamura YI, Chua Jr SC, Xu AW, Barsh GS, Rossetti L, Accili D 2006 Forkhead protein FoxO1 mediates Agrpdependent effects of leptin on food intake. Nat Med 12:534-540
-
(2006)
Nat Med
, vol.12
, pp. 534-540
-
-
Kitamura, T.1
Feng, Y.2
Kitamura, Y.I.3
Chua Jr., S.C.4
Xu, A.W.5
Barsh, G.S.6
Rossetti, L.7
Accili, D.8
-
37
-
-
62749109421
-
Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin
-
Rahmouni K, Sigmund CD, Haynes WG, Mark AL 2009 Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin. Diabetes 58:536-542
-
(2009)
Diabetes
, vol.58
, pp. 536-542
-
-
Rahmouni, K.1
Sigmund, C.D.2
Haynes, W.G.3
Mark, A.L.4
-
38
-
-
78951481202
-
Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet
-
Keung W, Cadete VJ, Palaniyappan A, Jablonski A, Fischer M, Lopaschuk GD 2011 Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet. J Cardiovasc Pharmacol 57:103-113
-
(2011)
J Cardiovasc Pharmacol
, vol.57
, pp. 103-113
-
-
Keung, W.1
Cadete, V.J.2
Palaniyappan, A.3
Jablonski, A.4
Fischer, M.5
Lopaschuk, G.D.6
-
39
-
-
1842426694
-
Long-term effects of a fatty acid synthase inhibitor on obese mice: Food intake, hypothalamic neuropeptides, and UCP3
-
DOI 10.1016/j.bbrc.2004.03.026, PII S0006291X0400498X
-
Cha SH, Hu Z, Lane MD 2004 Long-term effects of a fatty acid synthase inhibitor on obese mice: food intake, hypothalamic neuropeptides, and UCP3. Biochem Biophys Res Commun 317:301-308 (Pubitemid 38452482)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.317
, Issue.2
, pp. 301-308
-
-
Cha, S.H.1
Hu, Z.2
Lane, M.D.3
-
40
-
-
62749140758
-
Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance
-
Bruce CR, Hoy AJ, Turner N, Watt MJ, Allen TL, Carpenter K, Cooney GJ, Febbraio MA, Kraegen EW 2009 Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance. Diabetes 58:550-558
-
(2009)
Diabetes
, vol.58
, pp. 550-558
-
-
Bruce, C.R.1
Hoy, A.J.2
Turner, N.3
Watt, M.J.4
Allen, T.L.5
Carpenter, K.6
Cooney, G.J.7
Febbraio, M.A.8
Kraegen, E.W.9
-
41
-
-
0036788292
-
AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats
-
Iglesias MA, Ye JM, Frangioudakis G, Saha AK, Tomas E, Ruderman NB, Cooney GJ, Kraegen EW 2002 AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats. Diabetes 51:2886-2894
-
(2002)
Diabetes
, vol.51
, pp. 2886-2894
-
-
Iglesias, M.A.1
Ye, J.M.2
Frangioudakis, G.3
Saha, A.K.4
Tomas, E.5
Ruderman, N.B.6
Cooney, G.J.7
Kraegen, E.W.8
-
42
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and Δ
-
DOI 10.1073/pnas.94.9.4312
-
Forman BM, Chen J, Evans RM 1997 Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and Δ. Proc Natl Acad Sci USA 94:4312-4317 (Pubitemid 27194238)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.9
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
43
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, Muoio DM 2008 Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab 7:45-56
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
Slentz, D.4
Mosedale, M.5
Ilkayeva, O.6
Bain, J.7
Stevens, R.8
Dyck, J.R.9
Newgard, C.B.10
Lopaschuk, G.D.11
Muoio, D.M.12
-
44
-
-
34547588219
-
Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
-
DOI 10.2337/db07-0093
-
Turner N, Bruce CR, Beale SM, Hoehn KL, So T, Rolph MS, Cooney GJ 2007 Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents. Diabetes 56:2085-2092 (Pubitemid 47195821)
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 2085-2092
-
-
Turner, N.1
Bruce, C.R.2
Beale, S.M.3
Hoehn, K.L.4
So, T.5
Rolph, M.S.6
Cooney, G.J.7
-
45
-
-
45549089279
-
High-fat diets cause insulin resistance despite an increase in muscle mitochondria
-
DOI 10.1073/pnas.0802057105
-
Hancock CR, Han DH, Chen M, Terada S, Yasuda T, Wright DC, Holloszy JO 2008 High-fat diets cause insulin resistance despite an increase in muscle mitochondria. Proc Natl Acad Sci USA 105: 7815-7820 (Pubitemid 351872721)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.22
, pp. 7815-7820
-
-
Hancock, C.R.1
Han, D.-H.2
Chen, M.3
Terada, S.4
Yasuda, T.5
Wright, D.C.6
Holloszy, J.O.7
-
46
-
-
0035133331
-
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
-
DOI 10.1007/s001250051596
-
Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS 2001 Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 44:173-183 (Pubitemid 32156201)
-
(2001)
Diabetologia
, vol.44
, Issue.2
, pp. 173-183
-
-
Hajduch, E.1
Balendran, A.2
Batty, I.H.3
Litherland, G.J.4
Blair, A.S.5
Downes, C.P.6
Hundal, H.S.7
-
47
-
-
0031841949
-
Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide
-
Summers SA, Garza LA, Zhou H, Birnbaum MJ 1998 Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide. Mol Cell Biol 18:5457-5464 (Pubitemid 28388128)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.9
, pp. 5457-5464
-
-
Summers, S.A.1
Garza, L.A.2
Zhou, H.3
Birnbaum, M.J.4
-
48
-
-
0034803855
-
Inhibition of insulin signaling and glycogen synthesis by phorbol dibutyrate in rat skeletal muscle
-
Lin Y, Itani SI, Kurowski TG, Dean DJ, Luo Z, Yaney GC, Ruderman NB 2001 Inhibition of insulin signaling and glycogen synthesis by phorbol dibutyrate in rat skeletal muscle. Am J Physiol Endocrinol Metab 281:E8-E15
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Lin, Y.1
Itani, S.I.2
Kurowski, T.G.3
Dean, D.J.4
Luo, Z.5
Yaney, G.C.6
Ruderman, N.B.7
-
49
-
-
0033834079
-
Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle
-
Ellis BA, Poynten A, Lowy AJ, Furler SM, Chisholm DJ, Kraegen EW, Cooney GJ 2000 Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle. Am J Physiol Endocrinol Metab 279:E554-E560
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Ellis, B.A.1
Poynten, A.2
Lowy, A.J.3
Furler, S.M.4
Chisholm, D.J.5
Kraegen, E.W.6
Cooney, G.J.7
|