Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 41, 2005, Pages 14557-14562

  Cha, Seung Hun ^a   Hu, Zhiyuan ^a   Chohnan, Shigeru ^b   Lane, M Daniel ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IBARAKI UNIVERSITY   (Japan)

Author keywords

Acetyl CoA carboxylase; Malonyl CoA; Obesity; Uncoupling protein 3

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; C 75; CARNITINE PALMITOYLTRANSFERASE; FATTY ACID; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; MALONYL COENZYME A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHENTOLAMINE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; ENERGY BALANCE; ENERGY EXPENDITURE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; FEEDING BEHAVIOR; FOOD INTAKE; HYPOTHALAMUS; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSCRIPTION INITIATION;

4-BUTYROLACTONE; ANIMALS; BLOTTING, WESTERN; CARNITINE O-PALMITOYLTRANSFERASE; CARRIER PROTEINS; DNA PRIMERS; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; HYPOTHALAMUS; ION CHANNELS; MALONYL COENZYME A; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION; PPAR ALPHA; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM;

EID: 26844446285     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507300102     Document Type: Article

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