Serine protease inhibitor, 4-(2-aminoethyl)-benzene sulfonyl fluoride, impairs IL-12-induced activation of pSTAT4β, NFκB, and select pro-inflammatory mediators from estrogen-treated mice

Immunobiology

Volumn 216, Issue 12, 2011, Pages 1264-1273

  Karpuzoglu, Ebru ^b   Gogal, Robert M ^b   Ansar Ahmed, S ^a  

^a CENTER FOR MOLECULAR MEDICINE AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Estrogen; IL 12; Lymphocytes; NF B; PSTAT4 ; Serine protease inhibitor; Shorter p50 isoform; Spleen

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; CONCANAVALIN A; ESTROGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR BETA2; INTERLEUKIN 6; MESSENGER RNA; PROTEIN BCL 3; PROTEIN P50; SERINE PROTEINASE INHIBITOR; STAT4 PROTEIN; STAT4 PROTEIN BETA; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; IN VIVO STUDY; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; TH1 CELL;

ANIMALS; CELLS, CULTURED; CYTOKINES; ESTROGENS; GENE EXPRESSION REGULATION; INFLAMMATION; INFLAMMATION MEDIATORS; MICE; MICE, INBRED C57BL; NF-KAPPA B; RECEPTORS, INTERLEUKIN-12; SERINE PROTEASES; SERINE PROTEINASE INHIBITORS; SPLEEN; SULFONES; T-BOX DOMAIN PROTEINS; TH1-TH2 BALANCE;

EID: 80054925749     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2011.07.003     Document Type: Article

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