Nuclear factor-κB activation and innate immune response in microbial pathogen infection

Biochemical Pharmacology

Volumn 60, Issue 8, 2000, Pages 1109-1114

  Naumann, Michael ^a  

^a MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

Helicobacter pylori; Inflammation; Innate immune response; NF B; Signal transduction

Indexed keywords

CD14 ANTIGEN; CHEMOKINE; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

BACTERIAL COLONIZATION; BACTERIAL INFECTION; GENE EXPRESSION REGULATION; HELICOBACTER PYLORI; HOST RESISTANCE; HUMAN; IMMUNOREACTIVITY; IMMUNOREGULATION; INFECTION RESISTANCE; INFLAMMATION; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0034668206     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00390-7     Document Type: Article

References (61)

1. Hedges S.R., Agace W.W., Svanborg C. Epithelial cytokine responses and mucosal cytokine networks. Trends Microbiol. 3:1995;266-271.
2. Karin M. How NF-κB is activated The role of the IκB kinase (IKK) complex . Oncogene. 18:1999;6867-6874.
3. Hatada E.N., Krappmann D., Scheidereit C. NF-κB and the innate immune response. Curr Opin Immunol. 12:2000;52-58.
4. Mercurio F., Manning A.M. Multiple signals converging on NF-κB. Curr Opin Cell Biol. 11:1999;226-232.
5. Henderson B., Poole S., Wilson M. Bacterial modulins A novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis . Microbiol Rev. 60:1996;316-341.
6. Agace W., Hedges S., Andersson U., Andersson J., Ceska M., Svanborg C. Selective cytokine production by epithelial cells following exposure to Escherichia coli. Infect Immun. 61:1993;602-609.
7. Naumann M., Wessler S., Bartsch C., Wieland B., Meyer T.F. Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines. J Exp Med. 186:1997;247-258.
8. Naumann M., Rudel T., Wieland B., Bartsch C., Meyer T.F. Coordinate activation of activator protein 1 and inflammatory cytokines in response to Neisseria gonorrhoeae epithelial cell contact involves stress response kinases. J Exp Med. 188:1998;1277-1286.
9. Hedges S., Agace W., Svensson M., Sjogren A.C., Ceska M., Svanborg C. Uroepithelial cells are part of a mucosal cytokine network. Infect Immun. 62:1994;2315-2321.
10. Pahl H.L. Activators and target genes of Rel/NF-κB transcription factors. Oncogene. 18:1999;6853-6866.
11. Kreft B., Bohnet S., Carstensen O., Hacker J., Marre R. Differential expression of interleukin-6, intracellular adhesion molecule 1, and major histocompatibility complex class II molecules in renal carcinoma cells stimulated with S. fimbriae of uropathogenic Escherichia coli. Infect Immun. 61:1993;3060-3063.
12. Goodwin C.S., Armstrong J.A., Marshall B.J. Campylobacter pyloridis, gastritis, and peptic ulceration. J Clin Pathol. 39:1986;353-365.
13. Sipponen P., Hyvärinen H., Seppäla K., Blaser M.J. Review article Pathogenesis of the transformation from gastritis to malignancy . Aliment Pharmacol Ther. 12:1998;61-71.
14. Covacci A., Telford J.L., Del Giudice G., Parsonnet J., Rappuoli R. Helicobacter pylori virulence and genetic geography. Science. 284:1999;1328-1333.
15. Segal E.D., Cha J., Lo J., Falkow S., Tompkins L.S. Altered state Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori . Proc Natl Acad Sci USA. 96:1999;14559-14564.
16. Stein M., Rappuoli R., Covacci A. Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation. Proc Natl Acad Sci USA. 97:2000;1263-1268.
17. Asahi M., Azuma T., Ito S., Ito Y., Suto H., Nagai Y., Tsubokawa M., Tohyama Y., Maeda S., Omata M., Suzuki T., Sasakawa C. Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells. J Exp Med. 191:2000;593-602.
18. Odenbreit S., Püls J., Sedlmaier B., Gerland E., Fischer W., Haas R. Translocation of Helicobacter pylori CagA into epithelial cells by type IV secretion. Science. 287:2000;1497-1500.
19. Backert S., Ziska E., Brinkmann V., Zimny-Arndt U., Fauconnier A., Jungblut P., Naumann M., Meyer T.F. Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus. Cell Microbiol. 2:2000;155-164.
20. Münzenmaier A., Lange C., Glocker E., Covacci A., Moran A., Bereswill S., Baeuerle P.A., Kist M., Pahl H.L. A secreted/shed product of Helicobacter pylori activates transcription factor nuclear factor-kappa-B. J Immunol. 159:1997;6140-6147.
21. Keates S., Hitti Y.S., Upton M., Kelly C.P. Helicobacter pylori infection activates NF-kappa B in gastric epithelial cells. Gastroenterology. 113:1997;1099-1109.
22. Glocker E., Lange C., Covacci A., Bereswill S., Kist M., Pahl H.L. Proteins encoded by the Cag pathogenicity island of Helicobacter pylori are required for NF-kappa-B activation. Infect Immun. 66:1998;2346-2348.
23. Sharma S.A., Tummuru M.K., Blaser M.J., Kerr L.D. Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells. J Immunol. 160:1998;2401-2407.
24. Naumann M., Wessler S., Bartsch C., Wieland B., Covacci A., Haas R., Meyer T.F. Activation of activator protein 1 and stress response kinases in gastric cells colonized by Helicobacter pylori encoding the pathogenicity island. J Biol Chem. 274:1999;31655-31662.
25. Bodger K., Crabtree J.E. Helicobacter pylori and gastric inflammation. Br Med Bull. 54:1998;139-150.
26. Cornelis G.R., Wolf-Watz H. The Yersinia Yop virulon A bacterial system for subverting eukaryotic cells . Mol Microbiol. 23:1997;861-867.
27. Palmer L.E., Hobbie S., Galian J.E., Bliska J.B. YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNFα production and downregulation of the MAP kinases p38 and JNK. Mol Microbiol. 27:1998;953-965.
28. Boland A., Cornelis G.R. Role of YopJ in suppression of tumor necrosis factor α release by macrophages during Yersinia infection. Infect Immun. 66:1998;1878-1884.
29. Schesser K., Splik A.K., Dukuzumuremyi J.M., Neurath M.F., Pettersson S., Wolf-Watz H. The YopJ locus is required for Yersinia-mediated inhibition of NF-κB activation and cytokine expression YopJ contains a eukaryotic SH2-like domain that is essential for its repressive activity . Mol Microbiol. 28:1998;1067-1079.
30. Monack D., Mecsas J., Ghori N., Falkow S. Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death. Proc Natl Acad Sci USA. 94:1997;10385-10390.
31. Ruckdeschel K., Harb S., Roggenkamp A., Hornef M., Zumbihl R., Kohler S., Heesemann J., Rouot B. Yersinia enteroclitica impairs activation of transcription factor NF-κB Involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor α production . J Exp Med. 187:1998;1069-1079.
32. Orth K., Palmer L.E., Bao Z.Q., Stewart S., Rudolph A.E., Bliska J.B., Dixon J.E. Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector. Science. 285:1999;1920-1923.
33. Freiberg C., Fellay R., Bairoch A., Broughton W.J., Perret X. Molecular basis of symbiosis between Rhizobium and legumes. Nature. 387:1997;394-401.
34. Hardt W.D., Galan J.E. A secreted Salmonella protein with homology to an avirulence determinant of plant pathogenic bacteria. Proc Natl Acad Sci USA. 94:1997;9887-9892.
35. Collins T., Read M.A., Neish A.S., Whitley M.Z., Thanos D., Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules NF-kappa B and cytokine-inducible enhancers . FASEB J. 9:1995;899-909.
36. Hoffmann J.A., Kafatos F.C., Janeway C.A., Ezekowitz R.A. Phylogenetic perspectives in innate immunity. Science. 284:1999;1313-1318.
37. Williams M., Rodriguez A., Kimbrell D., Eldon E. The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense. EMBO J. 16:1997;6120-6130.
38. Medzhitov R., Preston-Hurlburt P., Janeway C. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:1997;394-397.
39. Rock F., Hardiman G., Timans J., Kastelein R., Bazan J. A family of human receptors structurally related to Drosphila Toll. Proc Natl Acad Sci USA. 95:1998;588-593.
40. Takeuchi O., Kawai T., Sanjo H., Copeland N.G., Gilbert D.J., Jenkins N.A., Takeda K., Akira S. TLR6 A novel member of an expanding toll-like receptor family . Gene. 231:1999;59-65.
41. Beutler B. Tlr4 Central component of the sole mammalian LPS sensor . Curr Opin Immunol. 12:2000;20-26.
42. Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., Takeda K., Akira S. Toll-like receptor 4 (TLR4)-deficient mice are hyperresponsive to lipopolysaccharide Evidence for TLR4 as the Lps gene product . J Immunol. 162:1999;3749-3752.
43. Poltorak A., Riccardi-Castagnoli P., Citterio A., Beutler B. Physical contact between LPS and Tlr4 revealed by genetic complementation. Proc Natl Acad Sci USA. 97:2000;2163-2167.
44. Wright S.D. Toll, a new piece in the puzzle of innate immunity. J Exp Med. 189:2000;605-609.
45. Haziot A., Ferrero E., Kontgen F., Hijiya N., Yamamoto S., Silver J., Stewart C.L., Gloyert S.M. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity. 4:1996;407-414.
46. Schwandner R., Dziarski R., Wesche H., Rothe M., Kirschning C.J. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J Biol Chem. 274:1999;17406-17409.
47. Hirschfeld M., Kirschning C.J., Schwandner R., Wesche H., Weis J.H., Wooten R.M., Weis J.J. Cutting edge Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2 . J Immunol. 163:1999;2382-2386.
48. Brightbill H.D., Libraty D.H., Krutzik S.R., Yang R.B., Belisle J.T., Bleharski J.R., Maitland M., Norgard M.V., Plevy S.E., Smale S.T., Brennan P.J., Bloom B.R., Godowski P.J., Modlin R.L. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science. 285:1999;732-736.
49. Aliprantis A.O., Yang R.B., Mark M.R., Sugett S., Devaux B., Radolf J.D., Klimpel G.R., Godowski P., Zychlinsky A. Cell activation and apoptsis by bacterial lipoproteins through toll-like receptor 2. Science. 285:1999;736-739.
50. Yoshimura A., Lien E., Ingalls R.R., Tuomanen E., Dziarski R., Golenbock D. Cutting edge Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2 . J Immunol. 163:1999;1-5.
51. Anderson K.V. Toll signaling pathways in the innate immune response. Curr Opin Immunol. 12:2000;13-19.
52. Kopp E., Medzihitov R., Carothers J., Xiao C., Douglas I., Janeway C.A. ECSIT is an evolutionary conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev. 13:1999;2059-2071.
53. Liu H., Su Y.C., Becker E., Treisman J., Skolnik E.Y. A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshappen and activates Jun kinase. Curr Biol. 9:1999;101-104.
54. Ninomiya-Tsuji J., Kishimoto K., Hiyama A., Inoue J., Cao Z., Matsumoto K. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature. 398:1999;252-256.
55. Shinkura R., Kitada K., Matsuda F., Tashiro K., Ikuta K., Suzuki M., Kogishi K., Serikawa T., Honjo T. Alymphoplasia is caused by a point mutation in the mouse gene encoding NF-κB-inducing kinase. Nat Genet. 22:1999;74-77.
56. Takeda K., Tajeuchi O., Tsujimura T., Itami S., Adachi O., Kawai T., Sanjo H., Yoshikawa K., Terada N., Akira S. Limb and skin abnormalities in mice lacking IKKα Science. 284:1999;313-316.
57. Hu Y., Baud V., Delhase M., Zhang P., Deerinck T., Ellisman M., Johnson R., Karin M. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase. Science. 284:1999;316-320.
58. Li Q., Lu Q., Hwang J.Y., Büscher D., Lee K.F., Ispisuma-Belmonte J.C., Verma I.M. IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev. 13:1999;1322-1328.
59. Li Z.W., Chu W., Hu Y., Delhase M., Deerinck T., Ellisman M., Johnson R., Karin M. The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis. J Exp Med. 189:1999;1839-1845.
60. Li Q., Van Antwerp D., Mercurio F., Lee K.F., Verma I.M. Severe liver degeneration in mice lacking the IκB kinase 2 gene. Science. 284:1999;321-325.
61. Grosshans J., Schnorrer F., Nüsslein-Volhard C. Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal. Mech Dev. 81:1999;127-138.