Determination of the amino acid sequence requirements for catalysis by the highly proficient orotidine monophosphate decarboxylase

Protein Science

Volumn 20, Issue 11, 2011, Pages 1891-1906

  Yuan, Ji ^a   Cardenas, Ana Maria ^a   Gilbert, Hiram F ^a   Palzkill, Timothy ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Active site residue stringency; High proficiency; Information content; Orotidine decarboxylase

Indexed keywords

ASPARTIC ACID; CYSTEINE; OROTIDINE 5' PHOSPHATE DECARBOXYLASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ESCHERICHIA COLI; GENE LOCUS; MOLECULAR GENETICS; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BIOCATALYSIS; CATALYSIS; CATALYTIC DOMAIN; ESCHERICHIA COLI; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; OROTIDINE-5'-PHOSPHATE DECARBOXYLASE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT;

EID: 80054720806     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.728     Document Type: Article

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