Analysis of the context dependent sequence requirements of active site residues in the metallo-β-lactamase IMP-1

Journal of Molecular Biology

Volumn 344, Issue 3, 2004, Pages 653-663

  Materon, Isabel C ^a   Beharry, Zanna ^a   Huang, Wanzhi ^a   Perez, Carla ^a   Palzkill, Timothy ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

information content; randomization; selection; substrate specificity; lactamase

Indexed keywords

AMPICILLIN; CEFALORIDINE; CEFOTAXIME; IMIPENEM; PENICILLINASE;

ARTICLE; CHELATION; CODON; CONTROLLED STUDY; DNA SEQUENCE; ESCHERICHIA COLI; GENE IDENTIFICATION; GENE LIBRARY; GENE MUTATION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 7944238165     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.09.074     Document Type: Article

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