Identification of active antiviral compounds against a New York isolate of West Nile virus

Antiviral Research

Volumn 55, Issue 1, 2002, Pages 107-116

  Morrey, John D ^a   Smee, Donald F ^a   Sidwell, Robert W ^a   Tseng, Christopher ^b  

^a UTAH STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

6 Azauridine; Antiviral; Flavivirus; Ribavirin; West Nile virus

Indexed keywords

1 (4,5 DIHYDROXY 3 HYDROXYMETHYL 2 CYCLOPENTEN 1 YL)CYTOSINE; 3 DEAZAGUANOSINE; 3 DEAZANEPLANOCIN A; 5,6 DIHYDROAZACITIDINE; 6 BROMOTOYOCAMYCIN; 9 (2,3 DIHYDROXYPROPYL)ADENINE; ANTIVIRUS AGENT; AZACITIDINE; AZARIBINE; AZAURIDINE; AZAURIDINE DERIVATIVE; CYCLOPENTYLURACIL; ENZYME INHIBITOR; FLUOROURIDINE; FORMYCIN B; HYPERICIN; INOSINATE DEHYDROGENASE INHIBITOR; MYCOPHENOLIC ACID; NEUTRAL RED; OROTIDINE 5' PHOSPHATE DECARBOXYLASE; OROTIDINE 5' PHOSPHATE DECARBOXYLASE INHIBITOR; PIRAZOFURIN; RIBAMIDINE; RIBAVIRIN; SELENAZOFURIN; SURAMIN; THIOURACIL; TIAZOFURIN; UNCLASSIFIED DRUG; URIDINE 2',3' DIALDEHYDE; 2-THIO-6-AZAURIDINE; CYCLOPENTENYL CYTOSINE; CYTIDINE; DRUG DERIVATIVE; RIBONUCLEOSIDE; THIOURIDINE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; ASSAY; CERCOPITHECIDAE; CONTROLLED STUDY; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; EMBRYO; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; VERO CELL; VIRUS ISOLATION; VIRUS STRAIN; WEST NILE FLAVIVIRUS; ANIMAL; CERCOPITHECUS; COMPARATIVE STUDY; CYTOPATHOGENIC EFFECT; DRUG EFFECT; IC 50; ISOLATION AND PURIFICATION; PHYSIOLOGY; UNITED STATES; VIRUS REPLICATION;

ANIMAL; ANTIVIRAL AGENTS; AZAURIDINE; CERCOPITHECUS AETHIOPS; COMPARATIVE STUDY; CYTIDINE; CYTOPATHOGENIC EFFECT, VIRAL; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; MYCOPHENOLIC ACID; NEW YORK; RIBAVIRIN; RIBONUCLEOSIDES; SUPPORT, U.S. GOV'T, P.H.S.; THIOURIDINE; VERO CELLS; VIRUS REPLICATION; WEST NILE VIRUS; ANIMALS;

FLAVIVIRUS; WEST NILE VIRUS;

EID: 0035997936     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(02)00013-X     Document Type: Article

References (37)

1. Treatment of rabies in mice and foxes with antiviral compounds
2. Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo
3. Outbreak of West Nile-like viral encephalitis - New York
4. Guidelines for surveillance, prevention, and control of West Nile infection - United States
5. Update: West Nile virus activity - Northeastern United States
6. Selection of antiviral compounds active on several flaviviruses: Clinical perspectives
7. Antiviral substances inhibiting in vitro replication of several flaviviruses
8. RNA virus error catastrophe: Direct molecular test by using ribavirin
9. The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen
10. Antiviral agents: Characteristic activity spectrum depending on the molecular target with which they interact
11. Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine
12. Potentiation of the anti-HIV activity of zalcitabine and lamivudine by a CTP synthase inhibitor, 3-deazauridine
13. Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells
14. Effect of ribavirin and tributyl ribavirin on Argentine hemorrhagic fever (Junin virus) in guinea pigs
15. Herpes simplex virus skin infection in hairless mice: Treatment with antiviral compounds
16. Cyclopentenylcytosine. A carbocyclic nucleoside with antitumor and antiviral properties
17. Ribavirin prophylaxis and therapy for experimental Argentine hemorrhagic fever
18. Use of the yellow fever virus vaccine strain 17D for the study of strategies for the treatment of yellow fever virus infections
19. Potent inhibition of respiratory syncitial virus replication using a 2-5 A-antisense chimera targeted to signals within the virus genomic RNA
20. Antiviral action and selectivity of 6-azauridine
21. Changes in hepatitis C virus RNA viremia concentrations in long-term renal transplant patients after introduction of mycophenolate mofetil
22. Sindbis virus mutants resistant to mycophenolic acid and ribavirin
23. Effect of 1-β-D-ribafuranosyl-1,2,4-triazole-3-carboxamide (Virazole, ICN1229) on herpes and vaccinia keratitis and encephalitis in laboratory animals
24. Ribavirin: A review of antiviral efficacy
25. Twelve die of West Nile virus in Israel [news]
26. Antiviral activity and mode of action of ribavirin 5′-sulfamate against Semliki Forest virus
27. Mode of action of ribavirin against cowpox and monkeypox viruses
28. Novel Pyrazolo[3,4-D]pyrimidine nucleoside analog with broad-spectrum antiviral activity
29. Selective inhibition of arthropod-borne and arenavirus in vitro by 3′-fluoro-3′-deoxyadenosine
30. Inhibition of bluetongue and Colorado tick fever orbiviruses by selected antiviral substances
31. Evaluation of 6-azauridine and 5-iododeoxyuridine in the treatment of experimental viral infections
32. Ribavirin treatment of toga-, arena-, and bunyavirus infections in subhuman primates and other laboratory animal species
33. In vitro inhibition of cytidine triphosphate synthetase activity by cyclopentenyl cytosine in paediatric acute lymphocytic leukemia
34. Therapeutic effect of the antiviral agent ribavirin in Junin virus infection of primates
35. Comparison of the anti-respiratory syncytial virus activity and toxicity of papaverine hydrochloride and pyrazofurin in vitro and in vivo
36. West Nile virus: A migrating arbovirus of current interest
37. Biohazards - Emerging diseases. A plum of an Island