SCOPUS 정보 검색 플랫폼

Volumn 64, Issue 10, 2011, Pages 1390-1396

Synthesis and pharmacological evaluation of novel homocamptothecin- dihydropyridine derivative conjugates as potent topoisomerase i inhibitors

(9) Zhu, Ling Jian a Zhuang, Chun Lin a Lei, Ning b Sheng, Chun Quan a Guo, Wei a Miao, Zhen Yuan a Liu, Wen Feng a Yao, Jian Zhong a Zhang, Wan Nian a

a SECOND MILITARY MEDICAL UNIVERSITY (China)

b Lian Yun Gang JARI Pharmaceutical Co Ltd (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUMOUR ACTIVITY; CYTOTOXIC ACTIVITIES; DIHYDROPYRIDINES; DNA TOPOISOMERASE; INHIBITION ACTIVITY; SYNTHETIC ROUTES; TOPOISOMERASE I; TUMOUR CELLS;

CELL CULTURE; CYTOTOXICITY; PLASMA STABILITY;

PYRIDINE;

EID: 80054680667 PISSN: 00049425 EISSN: None Source Type: Journal
DOI: 10.1071/CH11091 Document Type: Article

Times cited : (6)

References (28)

1
- 7144248725
- doi:10.1021/JA00968A057
- M. E.Wall,M. C.Wani, C. E. Cook,K. H. Palmer,A. T.McPhail,G. A. Sim, J. Am. Chem. Soc. 1966, 88, 3888. doi:10.1021/JA00968A057
- (1966) J. Am. Chem. Soc. , vol.88 , pp. 3888
- Wall, M.E.¹ Wani, M.C.² Cook, C.E.³ Palmer, K.H.⁴ McPhail, A.T.⁵ Sim, G.A.⁶

2
- 0036431991
- Current status and perspectives in the development of camptothecins
- DOI 10.2174/1381612023392801
- F. Zunino, S. Dallavalleb, D. Laccabuea, G. Berettaa, L. Merlinib, G. Pratesi, Curr. Pharm. Des. 2002, 8, 2505. doi:10.2174/ 1381612023392801 (Pubitemid 35331535)
- (2002) Current Pharmaceutical Design , vol.8 , Issue.27 , pp. 2505-2520
- Zunino, F.¹ Dallavalle, S.² Laccabue, D.³ Beretta, G.⁴ Merlini, L.⁵ Pratesi, G.⁶

3
- 67650682519
- doi:10.1021/CR900097C
- Y. Pommier, Chem. Rev. 2009, 109, 2894. doi:10.1021/CR900097C
- (2009) Chem. Rev. , vol.109 , pp. 2894
- Pommier, Y.¹

4
- 1542507062
- Camptothecin: Current perspectives
- DOI 10.1016/j.bmc.2003.11.036, PII S0968089603008848
- C. J. Thomas, N. J. Rahier, S. M. Hecht, Bioorg. Med. Chem. 2004, 12, 1585. doi:10.1016/J.BMC.2003.11.036 (Pubitemid 38344159)
- (2004) Bioorganic and Medicinal Chemistry , vol.12 , Issue.7 , pp. 1585-1604
- Thomas, C.J.¹ Rahier, N.J.² Hecht, S.M.³

5
- 0036399299
- doi:10.2165/ 00003495-200262140-00004
- H. Ulukan, P. W. Swaan, Drugs 2002, 62, 2039. doi:10.2165/ 00003495-200262140-00004
- (2002) Drugs , vol.62 , pp. 2039
- Ulukan, H.¹ Swaan, P.W.²

6
- 0030931517
- BN 80245: An E-ring modified camptothecin with potent antiproliferative and topoisomerase I inhibitory activities
- DOI 10.1016/S0960-894X(97)00398-3, PII S0960894X97003983
- O. Lavergne, L. Lesueur-Ginot, F. P. Rodas, D. C. H. Bigg, Bioorg. Med. Chem. Lett. 1997, 7, 2235. doi:10.1016/S0960-894X(97)00398-3 (Pubitemid 27387420)
- (1997) Bioorganic and Medicinal Chemistry Letters , vol.7 , Issue.17 , pp. 2235-2238
- Lavergne, O.¹ Lesueur-Ginot, L.² Rodas, F.P.³ Bigg, D.C.H.⁴

7
- 0033598698
- doi:10.1021/BI990947H
- C. Bailly, A. Lansiaux, L. Dassonneville, D. Demarquay, H. Coulomb, M. Huchet, O. Lavergne, D. C. Bigg, Biochemistry 1999, 38, 15556. doi:10.1021/BI990947H
- (1999) Biochemistry , vol.38 , pp. 15556
- Bailly, C.¹ Lansiaux, A.² Dassonneville, L.³ Demarquay, D.⁴ Coulomb, H.⁵ Huchet, M.⁶ Lavergne, O.⁷ Bigg, D.C.⁸

8
- 0032585548
- Homocamptothecins: Synthesis and antitumor activity of novel E-ring- modified camptothecin analogues
- DOI 10.1021/jm980400l
- O. Lavergne, L. Lesueur-Ginot, R. F. Pla, P. G. Kasprzyk, J. Pommier, D. Demarquay, G. Prevost, G. Ulibarri, A. Rolland, A. M. Schiano- Liberatore, J. Harnett, D. Pons, J. Camara, D. C. Bigg, J. Med. Chem. 1998, 41, 5410. doi:10.1021/JM980400L (Pubitemid 29031325)
- (1998) Journal of Medicinal Chemistry , vol.41 , Issue.27 , pp. 5410-5419
- Lavergne, O.¹ Lesueur-Ginot, L.² Rodas, F.P.³ Kasprzyk, P.G.⁴ Pommier, J.⁵ Demarquay, D.⁶ Prevost, G.⁷ Ulibarri, G.⁸ Rolland, A.⁹ Schiano-Liberatore, A.-M.¹⁰ Harnett, J.¹¹ Pons, D.¹² Camara, J.¹³ Bigg, D.C.H.¹⁴

9
- 0033530146
- BN 80927: A novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II
- DOI 10.1016/S0960-894X(99)00428-X, PII S0960894X9900428X
- O. Lavergne, J. Harnett, A. Rolland, C. Lanco, L. Lesueur-Ginot, D. Demarquay, M. Huchet, H. Coulomb, D. C. H. Bigg, Bioorg. Med. Chem. Lett. 1999, 9, 2599. doi:10.1016/S0960-894X(99)00428-X (Pubitemid 29435546)
- (1999) Bioorganic and Medicinal Chemistry Letters , vol.9 , Issue.17 , pp. 2599-2602
- Lavergne, O.¹ Harnett, J.² Rolland, A.³ Lanco, C.⁴ Lesueur-Ginot, L.⁵ Demarquay, D.⁶ Huchet, M.⁷ Coulomb, H.⁸ Bigg, D.C.H.⁹

10
- 0034214095
- Topoisomerase I-mediated antiproliferative activity of enantiomerically pure fluorinated homocamptothecins
- DOI 10.1021/jm000129j
- O. Lavergne, D. Demarquay, C. Bailly, C. Lanco, A. Rolland, M. Huchet, H. Coulomb, N. Muller, N. Baroqqi, J. Camara, C. Le Breton, E. Manqinot, J. B. Cazaux, D. C. Bigg, J. Med. Chem. 2000, 43, 2285. doi:10.1021/JM000129J (Pubitemid 30354554)
- (2000) Journal of Medicinal Chemistry , vol.43 , Issue.11 , pp. 2285-2289
- Lavergne, O.¹ Demarquay, D.² Bailly, C.³ Lanco, C.⁴ Rolland, A.⁵ Huchet, M.⁶ Coulomb, H.⁷ Muller, N.⁸ Baroggi, N.⁹ Camara, J.¹⁰ Le Breton, C.¹¹ Manginot, E.¹² Cazaux, J.-B.¹³ Bigg, D.C.H.¹⁴

11
- 0033549870
- doi:10.1021/ JM9902279
- D. Bom, D. P. Curran, A. J. Chavan, S. Kruszewski, S. G. Zimmer, K. A. Fraley, T. G. Burke, J. Med. Chem. 1999, 42, 3018. doi:10.1021/ JM9902279
- (1999) J. Med. Chem. , vol.42 , pp. 3018
- Bom, D.¹ Curran, D.P.² Chavan, A.J.³ Kruszewski, S.⁴ Zimmer, S.G.⁵ Fraley, K.A.⁶ Burke, T.G.⁷

12
- 33747129180
- Synthesis and biological assays of E-ring analogs of camptothecin and homocamptothecin
- DOI 10.1016/j.bmc.2006.05.073, PII S0968089606004408, Tetrahedron Prize for Creativity in Organic Chemistry 2005: B. Giese
- R. S. Tangirala, S. Antony, K. Agama, Y. Pommier, B. D. Anderson, R. Bevins, D. P. Curran, Bioorg. Med. Chem. 2006, 14, 6202. doi:10.1016/J.BMC.2006. 05.073 (Pubitemid 44224089)
- (2006) Bioorganic and Medicinal Chemistry , vol.14 , Issue.18 , pp. 6202-6212
- Tangirala, R.S.¹ Antony, S.² Agama, K.³ Pommier, Y.⁴ Anderson, B.D.⁵ Bevins, R.⁶ Curran, D.P.⁷

13
- 0141455147
- H. Gelderblom, R. Salazar, J. Verweij, G. Pentheroudakis, M. J. De Jonge, M. Devlin, C. van Hooije, F. Seguy, R. Obach, J. Prunonosa, P. Principe, C. Twelves, Clin. Cancer Res. 2003, 9, 4101.
- (2003) Clin. Cancer Res. , vol.9 , pp. 4101
- Gelderblom, H.¹ Salazar, R.² Verweij, J.³ Pentheroudakis, G.⁴ De Jonge, M.J.⁵ Devlin, M.⁶ Van Hooije, C.⁷ Seguy, F.⁸ Obach, R.⁹ Prunonosa, J.¹⁰ Principe, P.¹¹ Twelves, C.¹²

14
- 3142686746
- BN80927: A novel homocamptothechin that inhibits proliferation of human tumor cells in vitro and in vivo
- DOI 10.1158/0008-5472.CAN-03-3872
- D. Demarquay, M. Huchet, H. Coulomb, L. Lesueur-Ginot, O. Lavergne, J. Camara, P. G. Kasprzyk, G. Prevost, D. C. Bigg, Cancer Res. 2004, 64, 4942. doi:10.1158/0008-5472.CAN-03-3872 (Pubitemid 38924541)
- (2004) Cancer Research , vol.64 , Issue.14 , pp. 4942-4949
- Demarquay, D.¹ Huchet, M.² Coulomb, H.³ Lesueur-Ginot, L.⁴ Lavergne, O.⁵ Camara, J.⁶ Kasprzyk, P.G.⁷ Prevost, G.⁸ Bigg, D.C.H.⁹

15
- 38549161260
- doi:10.1124/ MOL.107.041178
- Z. Liao, R. W. Robey, J. Guirouilh-Barbat, K. K. To, O. Polgar, S. E. Bates, Y. Pommier, Mol. Pharmacol. 2008, 73, 490. doi:10.1124/ MOL.107.041178
- (2008) Mol. Pharmacol. , vol.73 , pp. 490
- Liao, Z.¹ Robey, R.W.² Guirouilh-Barbat, J.³ To, K.K.⁴ Polgar, O.⁵ Bates, S.E.⁶ Pommier, Y.⁷

16
- 77954348852
- doi:10.1016/J.EJMECH.2010.02.051
- L. J. Zhu, Z. Y. Miao, C. Q. Sheng, W. Guo, J. Z. Yao, W. F. Liu, X. Y. Che, W. Y. Wang, P. F. Cheng, W. N. Zhang, Eur. J. Med. Chem. 2010, 45, 2726. doi:10.1016/J.EJMECH.2010.02.051
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 2726
- Zhu, L.J.¹ Miao, Z.Y.² Sheng, C.Q.³ Guo, W.⁴ Yao, J.Z.⁵ Liu, W.F.⁶ Che, X.Y.⁷ Wang, W.Y.⁸ Cheng, P.F.⁹ Zhang, W.N.¹⁰

17
- 38849193487
- New homocamptothecins: Synthesis, antitumor activity, and molecular modeling
- DOI 10.1016/j.bmc.2007.10.046, PII S0968089607009157
- Z. Y. Miao, C. Q. Sheng, W. N. Zhang, H. T. Ji, J. Zhang, L. C. Shao, L. You, M. Zhang, J. Z. Yao, X. Y. Che, Bioorg. Med. Chem. 2008, 16, 1493. doi:10.1016/J.BMC.2007.10.046 (Pubitemid 351191756)
- (2008) Bioorganic and Medicinal Chemistry , vol.16 , Issue.3 , pp. 1493-1510
- Miao, Z.¹ Sheng, C.² Zhang, W.³ Ji, H.⁴ Zhang, J.⁵ Shao, L.⁶ You, L.⁷ Zhang, M.⁸ Yao, J.⁹ Che, X.¹⁰

18
- 77951203595
- doi:10.1016/J.BMC.2010.03.039
- Z. Miao, J. Zhang, L. You, J. Wang, C. Sheng, J. Yao, W. Zhang, H. Feng, W. Guo, L. Zhou, W. Liu, L. Zhu, P. Cheng, X. Che, W. Wang, C. Luo, Y. Xu, G. Dong, Bioorg. Med. Chem. 2010, 18, 3140. doi:10.1016/J.BMC.2010.03.039
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 3140
- Miao, Z.¹ Zhang, J.² You, L.³ Wang, J.⁴ Sheng, C.⁵ Yao, J.⁶ Zhang, W.⁷ Feng, H.⁸ Guo, W.⁹ Zhou, L.¹⁰ Liu, W.¹¹ Zhu, L.¹² Cheng, P.¹³ Che, X.¹⁴ Wang, W.¹⁵ Luo, C.¹⁶ Xu, Y.¹⁷ Dong, G.¹⁸

19
- 77950859671
- doi:10.1016/J.EJMECH.2010.01.063
- W. Guo, Z. Miao, C. Sheng, J. Yao, H. Feng, W. Zhang, L. Zhu, W. Liu, P. Cheng, J. Zhang, X. Che, W. Wang, C. Luo, Y. Xu, Eur. J. Med. Chem. 2010, 45, 2223. doi:10.1016/J.EJMECH.2010.01.063
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 2223
- Guo, W.¹ Miao, Z.² Sheng, C.³ Yao, J.⁴ Feng, H.⁵ Zhang, W.⁶ Zhu, L.⁷ Liu, W.⁸ Cheng, P.⁹ Zhang, J.¹⁰ Che, X.¹¹ Wang, W.¹² Luo, C.¹³ Xu, Y.¹⁴

20
- 36749018204
- Privileged structures: A useful concept for the rational design of new lead drug candidates
- DOI 10.2174/138955707782331722
- C. D. Duarte, E. J. Barreiro, C. A. Fraga, Mini Rev. Med. Chem. 2007, 7, 1108. doi:10.2174/138955707782331722 (Pubitemid 350200217)
- (2007) Mini-Reviews in Medicinal Chemistry , vol.7 , Issue.11 , pp. 1108-1119
- Duarte, C.D.¹ Barreiro, E.J.² Fraga, C.A.M.³

21
- 0034519777
- doi:10.1016/S0223- 5234(00)01189-2
- C. O. Kappe, Eur. J. Med. Chem. 2000, 35, 1043. doi:10.1016/S0223- 5234(00)01189-2
- (2000) Eur. J. Med. Chem. , vol.35 , pp. 1043
- Kappe, C.O.¹

22
- 0026065919
- doi:10.1021/ JM00106A048
- K. S. Atwal, B. N. Swanson, S. E. Unger, D. M. Floyd, S. Moreland, A. Hedberg, B. C. O'Reilly, J. Med. Chem. 1991, 34, 806. doi:10.1021/ JM00106A048
- (1991) J. Med. Chem. , vol.34 , pp. 806
- Atwal, K.D.¹ Swanson, B.N.² Unger, S.E.³ Floyd, D.M.⁴ Moreland, S.⁵ Hedberg, A.⁶ O'Reilly, B.C.⁷

23
- 0034601292
- 2 receptors
- DOI 10.1016/S0165-1838(00)00128-4, PII S0165183800001284
- K. A. Jacobson, Y. C. Kim, B. F. King, J. Auton. Nerv. Syst. 2000, 81, 152. doi:10.1016/S0165-1838(00)00128-4 (Pubitemid 30408492)
- (2000) Journal of the Autonomic Nervous System , vol.81 , Issue.1-3 , pp. 152-157
- Jacobson, K.A.¹ Kim, Y.-C.² King, B.F.³

24
- 0029834607
- P. Hamet, Hypertension 1996, 28, 321.
- (1996) Hypertension , vol.28 , pp. 321
- Hamet, P.¹

25
- 0037091088
- Is there an association between hypertension and cancer mortality?
- DOI 10.1016/S0002-9343(02)01049-5, PII S0002934302010495
- E. Grossman, F. H. Messerli, V. Boyko, U. Goldbourt, Am. J. Med. 2002, 112, 479. doi:10.1016/S0002-9343(02)01049-5 (Pubitemid 34450709)
- (2002) American Journal of Medicine , vol.112 , Issue.6 , pp. 479-486
- Grossman, E.¹ Messerli, F.H.² Boyko, V.³ Goldbourt, U.⁴

26
- 17144371295
- doi:10.1021/ JM049146P
- B. L. Staker, M. D. Feese, M. Cushman, Y. Pommier, D. Zembower, L. Stewart, A. B. Burgin, J. Med. Chem. 2005, 48, 2336. doi:10.1021/ JM049146P
- (2005) J. Med. Chem. , vol.48 , pp. 2336
- Staker, B.L.¹ Feese, M.D.² Cushman, M.³ Pommier, Y.⁴ Zembower, D.⁵ Stewart, L.⁶ Burgin, A.B.⁷

27
- 0004913196
- doi:10.1021/JO01302A020
- R. M. Kellogg, T. J. Van Bergen, H. Van Doren, D. Hedstrand, J. Kooi, W. H. Kruizinga, C. B. Troostwijk, J. Org. Chem. 1980, 45, 2854. doi:10.1021/JO01302A020
- (1980) J. Org. Chem. , vol.45 , pp. 2854
- Kellogg, R.M.¹ Van Bergen, T.J.² Van Doren, H.³ Hedstrand, D.⁴ Kooi, J.⁵ Kruizinga, W.H.⁶ Troostwijk, C.B.⁷

28
- 0025948430
- S. Sawada, K. Nokata, T. Furuta, T. Yokokura, T. Miyasaka, Chem. Pharm. Bull. (Tokyo) 1991, 39, 2574.
- (1991) Chem. Pharm. Bull. (Tokyo) , vol.39 , pp. 2574
- Sawada, S.¹ Nokata, K.² Furuta, T.³ Yokokura, T.⁴ Miyasaka, T.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.