Regulated expression of neuronal SIRT1 and related genes by aging and neuronal β2-containing nicotinic cholinergic receptors

Neuroscience

Volumn 196, Issue , 2011, Pages 189-202

  Huang, P S ^a,c   Son, J H ^b   Abbott, L C ^a   Winzer Serhan, U H ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A M COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

Hippocampus; In situ hybridization; Longevity genes; NAChR; Neocortex; Nicotine

Indexed keywords

KU ANTIGEN; MESSENGER RNA; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NICOTINIC RECEPTOR BETA2; PROTEIN P53; PROTEIN UCP5; SIRTUIN 1; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN SIZE; CELL AGING; CELL DENSITY; CONTROLLED STUDY; FRONTAL CORTEX; GENE EXPRESSION REGULATION; GENOTYPE; HABENULA; HIPPOCAMPUS; IN SITU HYBRIDIZATION; LONGEVITY; MALE; MOUSE; NEOCORTEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; WILD TYPE;

AGING; ANIMALS; ANTIGENS, NUCLEAR; ATROPHY; CEREBRAL CORTEX; CHOLINERGIC NEURONS; CYTOKINES; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; RECEPTORS, NICOTINIC; SIRTUIN 1;

EID: 80054027568     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.09.007     Document Type: Article

References (63)

1. Agarwal B., Baur J.A. Resveratrol and life extension. Ann N Y Acad Sci 2011, 1215:138-143.
2. Andrews Z.B., Diano S., Horvath T.L. Mitochondrial uncoupling proteins in the CNS: in support of function and survival. Nat Rev Neurosci 2005, 6:829-840.
3. Armstrong J.F., Kaufman M.H., Harrison D.J., Clarke A.R. High-frequency developmental abnormalities in p53-deficient mice. Curr Biol 1995, 5:931-936.
4. Bao J., Lei D., Du Y., Ohlemiller K.K., Beaudet A.L., Role L.W. Requirement of nicotinic acetylcholine receptor subunit beta2 in the maintenance of spiral ganglion neurons during aging. J Neurosci 2005, 25:3041-3045.
5. Barnes C.A. Neurological and behavioral investigations of memory failure in aging animals. Int J Neurol 1987, 21-22:130-136.
6. Bitterman K.J., Anderson R.M., Cohen H.Y., Latorre-Esteves M., Sinclair D.A. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 2002, 277:45099-45107.
7. Borradaile N.M., Pickering J.G. NAD(+), sirtuins, and cardiovascular disease. Curr Pharm Des 2009, 15:110-117.
8. Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., Hu L.S., Cheng H.L., Jedrychowski M.P., Gygi S.P., Sinclair D.A., Alt F.W., Greenberg M.E. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004, 303:2011-2015.
9. Buss R.R., Sun W., Oppenheim R.W. Adaptive roles of programmed cell death during nervous system development. Annu Rev Neurosci 2006, 29:1-35.
10. Calhoun M.E., Kurth D., Phinney A.L., Long J.M., Hengemihle J., Mouton P.R., Ingram D.K., Jucker M. Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice. Neurobiol Aging 1998, 19:599-606.
11. Cameron H.A., Woolley C.S., McEwen B.S., Gould E. Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience 1993, 56:337-344.
12. Chen J., Zhou Y., Mueller-Steiner S., Chen L.F., Kwon H., Yi S., Mucke L., Gan L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. J Biol Chem 2005, 280:40364-40374.
13. Cohen H.Y., Lavu S., Bitterman K.J., Hekking B., Imahiyerobo T.A., Miller C., Frye R., Ploegh H., Kessler B.M., Sinclair D.A. Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol Cell 2004, 13:627-638.
14. Cohen H.Y., Miller C., Bitterman K.J., Wall N.R., Hekking B., Kessler B., Howitz K.T., Gorospe M., de Cabo R., Sinclair D.A. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004, 305:390-392.
15. Cooper E., Couturier S., Ballivet M. Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor. Nature 1991, 350:235-238.
16. Deupree D.L., Bradley J., Turner D.A. Age-related alterations in potentiation in the CA1 region in F344 rats. Neurobiol Aging 1993, 14:249-258.
17. Giannakou M.E., Partridge L. The interaction between FOXO and SIRT1: tipping the balance towards survival. Trends Cell Biol 2004, 14:408-412.
18. Grady S.R., Moretti M., Zoli M., Marks M.J., Zanardi A., Pucci L., Clementi F., Gotti C. Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release. J Neurosci 2009, 29:2272-2282.
19. Harrist A., Beech R.D., King S.L., Zanardi A., Cleary M.A., Caldarone B.J., Eisch A., Zoli M., Picciotto M.R. Alteration of hippocampal cell proliferation in mice lacking the beta 2 subunit of the neuronal nicotinic acetylcholine receptor. Synapse 2004, 54:200-206.
20. Hastings N.B., Gould E. Rapid extension of axons into the CA3 region by adult-generated granule cells. J Comp Neurol 1999, 413:146-154.
21. Hellström-Lindahl E., Court J.A. Nicotinic acetylcholine receptors during prenatal development and brain pathology in human aging. Behav Brain Res 2000, 113:159-168.
22. Herrup K., Yang Y. Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?. Nat Rev Neurosci 2007, 8:368-378.
23. Hoekman M.F., Jacobs F.M., Smidt M.P., Burbach J.P. Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr Patterns 2006, 6:134-140.
24. Huang L.Z., Winzer-Serhan U.H. Nicotine regulates mRNA expression of feeding peptides in the arcuate nucleus in neonatal rat pups. Dev Neurobiol 2007, 67:363-377.
25. Imai S., Armstrong C.M., Kaeberlein M., Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000, 403:795-800.
26. Ju Y.J., Lee K.H., Park J.E., Yi Y.S., Yun M.Y., Ham Y.H., Kim T.J., Choi H.M., Han G.J., Lee J.H., Lee J., Han J.S., Lee K.M., Park G.H. Decreased expression of DNA repair proteins Ku70 and Mre11 is associated with aging and may contribute to the cellular senescence. Exp Mol Med 2006, 38:686-693.
27. Kaeberlein M., McVey M., Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 1999, 13:2570-2580.
28. Kanfi Y., Peshti V., Gozlan Y.M., Rathaus M., Gil R., Cohen H.Y. Regulation of SIRT1 protein levels by nutrient availability. FEBS Lett 2008, 582:2417-2423.
29. Karlin A. Emerging structure of the nicotinic acetylcholine receptors. Nat Rev Neurosci 2002, 3:102-114.
30. Kim D., Nguyen M.D., Dobbin M.M., Fischer A., Sananbenesi F., Rodgers J.T., Delalle I., Baur J.A., Sui G., Armour S.M., Puigserver P., Sinclair D.A., Tsai L.H. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 2007, 26:3169-3179.
31. Kim-Han J.S., Reichert S.A., Quick K.L., Dugan L.L. BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production. J Neurochem 2001, 79:658-668.
32. Lin S.J., Defossez P.A., Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000, 289:2126-2128.
33. Liu D., Chan S.L., de Souza-Pinto N.C., Slevin J.R., Wersto R.P., Zhan M., Mustafa K., de Cabo R., Mattson M.P. Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress. Neuromol Med 2006, 8:389-414.
34. Lovell M.A., Markesbery W.R. Oxidative damage in mild cognitive impairment and early Alzheimer's disease. J Neurosci Res 2007, 85:3036-3040.
35. Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001, 107:137-148.
36. Mechawar N., Saghatelyan A., Grailhe R., Scoriels L., Gheusi G., Gabellec M.M., Lledo P.M., Changeux J.P. Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proc Natl Acad Sci U S A 2004, 101:9822-9826.
37. Michan S., Sinclair D. Sirtuins in mammals: insights into their biological function. Biochem J 2007, 404:1-13.
38. Narasimhaiah R., Tuchman A., Lin S.L., Naegele J.R. Oxidative damage and defective DNA repair is linked to apoptosis of migrating neurons and progenitors during cerebral cortex development in Ku70-deficient mice. Cereb Cortex 2005, 15:696-707.
39. Nemoto S., Fergusson M.M., Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004, 306:2105-2108.
40. Picciotto M.R., Zoli M. Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Front Biosci 2008, 13:492-504.
41. Picciotto M.R., Zoli M., Rimondini R., Léna C., Marubio L.M., Pich E.M., Fuxe K., Changeux J.P. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature 1998, 391:173-177.
42. + hematopoietic stem and progenitor cells. Mech Ageing Dev 2007, 128:503-510.
43. Quick M.W., Ceballos R.M., Kasten M., McIntosh J.M., Lester R.A. Alpha3beta4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons. Neuropharmacology 1999, 38:769-783.
44. Ramadori G., Lee C.E., Bookout A.L., Lee S., Williams K.W., Anderson J., Elmquist J.K., Coppari R. Brain SIRT1: anatomical distribution and regulation by energy availability. J Neurosci 2008, 28:9989-9996.
45. Rasmussen T., Schliemann T., Sørensen J.C., Zimmer J., West M.J. Memory impaired aged rats: no loss of principal hippocampal and subicular neurons. Neurobiol Aging 1996, 17:143-147.
46. Revollo J.R., Grimm A.A., Imai S. The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J Biol Chem 2004, 279:50754-50763.
47. Rosen G., Williams A., Capra J., Connolly M., Cruz B., Lu L., Airey D., Kulkarni K., Williams R. The Mouse Brain Library. Int Mouse Genome Conference 2000, 14:166. www.mbl.org.
48. Salminen A., Kaarniranta K. NF-kappaB signaling in the aging process. J Clin Immunol 2009, 29:397-405.
49. Sanchis D., Fleury C., Chomiki N., Goubern M., Huang Q., Neverova M., Grégoire F., Easlick J., Raimbault S., Lévi-Meyrueis C., Miroux B., Collins S., Seldin M., Richard D., Warden C., Bouillaud F., Ricquier D. BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast. J Biol Chem 1998, 273:34611-34615.
50. Sargent P.B. The diversity of neuronal nicotinic acetylcholine receptors. Annu Rev Neurosci 1993, 16:403-443.
51. Sibille E., Su J., Leman S., Le Guisquet A.M., Ibarguen-Vargas Y., Joeyen-Waldorf J., Glorioso C., Tseng G.C., Pezzone M., Hen R., Belzung C. Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity. Mol Psychiatry 2007, 12:1042-1056. 1975.
52. Smith G.C., Jackson S.P. The DNA-dependent protein kinase. Genes Dev 1999, 13:916-934.
53. Socci D.J., Sanberg P.R., Arendash G.W. Nicotine enhances Morris water maze performance of young and aged rats. Neurobiol Aging 1995, 16:857-860.
54. Stanfield B.B., Trice J.E. Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections. Exp Brain Res 1988, 72:399-406.
55. Sugano T., Yanagita T., Yokoo H., Satoh S., Kobayashi H., Wada A. Enhancement of insulin-induced PI3K/Akt/GSK-3beta and ERK signaling by neuronal nicotinic receptor/PKC-alpha/ERK pathway: up-regulation of IRS-1/-2 mRNA and protein in adrenal chromaffin cells. J Neurochem 2006, 98:20-33.
56. van der Veer E., Ho C., O'Neil C., Barbosa N., Scott R., Cregan S.P., Pickering J.G. Extension of human cell lifespan by nicotinamide phosphoribosyltransferase. J Biol Chem 2007, 282:10841-10845.
57. van Lookeren Campagne M., Gill R. Tumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain: comparison with expression of the cell cycle regulators p21Waf1/Cip1, p27Kip1, p57Kip2, p16Ink4a, cyclin G1, and the proto-oncogene Bax. J Comp Neurol 1998, 397:181-198.
58. Vaziri H., Dessain S.K., Ng Eaton E., Imai S.I., Frye R.A., Pandita T.K., Guarente L., Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001, 107:149-159.
59. von Bohlen und Halbach O., Unsicker K. Morphological alterations in the amygdala and hippocampus of mice during ageing. Eur J Neurosci 2002, 16:2434-2440.
60. Xu W., Orr-Urtreger A., Nigro F., Gelber S., Sutcliffe C.B., Armstrong D., Patrick J.W., Role L.W., Beaudet A.L., De Biasi M. Multiorgan autonomic dysfunction in mice lacking the beta2 and the beta4 subunits of neuronal nicotinic acetylcholine receptors. J Neurosci 1999, 19:9298-9305.
61. Yang H., Lavu S., Sinclair D.A. Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity?. Exp Gerontol 2006, 41:718-726.
62. Zarrindast M.R., Sadegh M., Shafaghi B. Effects of nicotine on memory retrieval in mice. Eur J Pharmacol 1996, 295:1-6.
63. Zoli M., Picciotto M.R., Ferrari R., Cocchi D., Changeux J.P. Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. EMBO J 1999, 18:1235-1244.