Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1

Journal of Biochemical and Molecular Toxicology

Volumn 25, Issue 5, 2011, Pages 320-329

  Cheng, Qiuqiong ^a   Taguchi, Keiko ^b   Aleksunes, Lauren M ^c   Manautou, José E ^c   Cherrington, Nathan J ^d   Yamamoto, Masayuki ^b   Slitt, Angela L ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Abcc4; Kelch Like ECH Associated Protein 1(Kea p1); Multidrug Resistance Associated Protein(Mrp); Nfe2Lz) Organic Anion Transporting Polypeptide (Oatp); Nuclear Factor E2 Related Factor 2(nrfz

Indexed keywords

CARRIER PROTEIN; CYTOCHROME P450; CYTOCHROME P450 2B10; CYTOCHROME P450 3A11; GLUTAMATE CYSTEINE LIGASE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; ORGANIC ANION TRANSPORTER; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SULFOTRANSFERASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME SUBUNIT; GENE ACTIVATION; GENE DELETION; LIVER; LIVER CELL; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; UPREGULATION; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSKELETAL PROTEINS; DRUG RESISTANCE, MULTIPLE; GENE DELETION; GENE EXPRESSION REGULATION; GLUTAMATE-CYSTEINE LIGASE; HEPATOCYTES; LIVER; MICE; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; ORGANIC ANION TRANSPORTERS; SIGNAL TRANSDUCTION;

MUS;

EID: 80053906100     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.20392     Document Type: Article

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