Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity

Molecular Pharmaceutics

Volumn 5, Issue 1, 2008, Pages 77-91

  Cheng, Qiuqiong ^a   Aleksunes, Lauren M ^b   Manautou, José E ^b   Cherrington, Nathan J ^c   Scheffer, George L ^d   Yamasaki, Hideki ^e   Slitt, Angela L ^a,f  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

^e BROWN UNIVERSITY   (United States)

^f UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Diabetes; Drug metabolizing enzymes; Mrp4; Multidrug resistance associated protein; Oatp1a1; Ob ob mice; Obesity; Organic anion transporting polypeptide; Transporters

Indexed keywords

CARRIER PROTEIN; CYTOCHROME P450 2B10; CYTOCHROME P450 4A14; DRUG METABOLIZING ENZYME; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SODIUM TAUROCHOLATE COTRANSPORTING POLYPEPTIDE; SULFOTRANSFERASE; SULFOTRANSFERASE 2A1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; KIDNEY; LIVER; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CYTOCHROME P-450 ENZYME SYSTEM; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; FEMALE; KIDNEY; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MIXED FUNCTION OXYGENASES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NADPH DEHYDROGENASE; OBESITY; ORGANIC ANION TRANSPORTERS; RNA, MESSENGER; STEROID HYDROXYLASES; SUBCELLULAR FRACTIONS;

EID: 39749101222     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp700114j     Document Type: Article

References (76)