The wiskott-aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling

Haematologica

Volumn 96, Issue 10, 2011, Pages 1415-1423

  Calvez, Ronan ^a,b   Lafouresse, Fanny ^a,b   de Meester, Julie ^a,b   Galy, Anne ^c   Valitutti, Salvatore ^a,b   Dupré, Loïc ^a,b  

^a University of Toulouse III   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c GÉNÉTHON   (France)

Author keywords

Immunological synapse; T lymphocytes; Wiskott aldrich syndrome

Indexed keywords

ACTIN; T LYMPHOCYTE RECEPTOR; WISKOTT ALDRICH SYNDROME PROTEIN;

ANTIGEN PRESENTING CELL; ARTICLE; CALCIUM TRANSPORT; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; LYMPHOCYTE PROLIFERATION; MICROTUBULE; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN STRUCTURE; T LYMPHOCYTE ACTIVATION; WISKOTT ALDRICH SYNDROME;

ANTIGEN-PRESENTING CELLS; CALCIUM; CD4-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELL LINE; HUMANS; IMMUNOLOGICAL SYNAPSES; LYMPHOCYTE ACTIVATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SUPERANTIGENS; WISKOTT-ALDRICH SYNDROME; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 80053626114     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.040204     Document Type: Article

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