메뉴 건너뛰기




Volumn 51, Issue 9, 2011, Pages 1774-1788

Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury

Author keywords

Cisplatin; Free radicals; Nephropathy; Poly(ADP ribose) polymerase

Indexed keywords

3 NITROTYROSINE; 5 AMINOISOQUINOLINE; CISPLATIN; CREATININE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 ACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 80053602773     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.08.006     Document Type: Article
Times cited : (80)

References (106)
  • 1
    • 0022879127 scopus 로고
    • Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity
    • F. Ries, and J. Klastersky Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity Am. J. Kidney Dis. 8 1986 368 379 (Pubitemid 17235084)
    • (1986) American Journal of Kidney Diseases , vol.8 , Issue.5 , pp. 368-379
    • Ries, F.1    Klastersky, J.2
  • 2
    • 0036738495 scopus 로고    scopus 로고
    • Cancer therapy and renal injury
    • R.W. Schrier Cancer therapy and renal injury J. Clin. Invest. 110 2002 743 745
    • (2002) J. Clin. Invest. , vol.110 , pp. 743-745
    • Schrier, R.W.1
  • 3
    • 18244379333 scopus 로고    scopus 로고
    • Cellular processing of platinum anticancer drugs
    • DOI 10.1038/nrd1691
    • D. Wang, and S.J. Lippard Cellular processing of platinum anticancer drugs Nat. Rev. Drug Discov. 4 2005 307 320 (Pubitemid 41130944)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.4 , pp. 307-320
    • Wang, D.1    Lippard, S.J.2
  • 4
    • 0035195536 scopus 로고    scopus 로고
    • Manganese superoxide dismutase attenuates cisplatin-induced renal injury: Importance of superoxide
    • C.A. Davis, H.S. Nick, and A. Agarwal Manganese superoxide dismutase attenuates cisplatin-induced renal injury: importance of superoxide J. Am. Soc. Nephrol. 12 2001 2683 2690 (Pubitemid 33115415)
    • (2001) Journal of the American Society of Nephrology , vol.12 , Issue.12 , pp. 2683-2690
    • Davis, C.A.1    Nick, H.S.2    Agarwal, A.3
  • 6
    • 0036738517 scopus 로고    scopus 로고
    • TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity
    • G. Ramesh, and W.B. Reeves TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity J. Clin. Invest. 110 2002 835 842
    • (2002) J. Clin. Invest. , vol.110 , pp. 835-842
    • Ramesh, G.1    Reeves, W.B.2
  • 7
    • 42149187768 scopus 로고    scopus 로고
    • Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies
    • DOI 10.1038/sj.ki.5002786, PII 5002786
    • N. Pabla, and Z. Dong Cisplatin nephrotoxicity: mechanisms and renoprotective strategies Kidney Int. 73 2008 994 1007 (Pubitemid 351543900)
    • (2008) Kidney International , vol.73 , Issue.9 , pp. 994-1007
    • Pabla, N.1    Dong, Z.2
  • 9
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
    • L. Virag, and C. Szabo The therapeutic potential of poly(ADP-ribose) polymerase inhibitors Pharmacol. Rev. 54 2002 375 429
    • (2002) Pharmacol. Rev. , vol.54 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 10
    • 18944390248 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
    • DOI 10.1038/nrd1718
    • P. Jagtap, and C. Szabo Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors Nat. Rev. Drug Discov. 4 2005 421 440 (Pubitemid 40704125)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.5 , pp. 421-440
    • Jagtap, P.1    Szabo, C.2
  • 12
    • 0036550855 scopus 로고    scopus 로고
    • Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice
    • F.G. Soriano, L. Liaudet, E. Szabo, L. Virag, J.G. Mabley, P. Pacher, and C. Szabo Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice Shock 17 2002 286 292
    • (2002) Shock , vol.17 , pp. 286-292
    • Soriano, F.G.1    Liaudet, L.2    Szabo, E.3    Virag, L.4    Mabley, J.G.5    Pacher, P.6    Szabo, C.7
  • 13
    • 21644454451 scopus 로고    scopus 로고
    • Role of nitrosative stress and activation of poly(ADP-ribose) polymerase-1 in cardiovascular failure associated with septic and hemorrhagic shock
    • DOI 10.2174/1570161054368580
    • O.V. Evgenov, and L. Liaudet Role of nitrosative stress and activation of poly(ADP-ribose) polymerase-1 in cardiovascular failure associated with septic and hemorrhagic shock Curr. Vasc. Pharmacol. 3 2005 293 299 (Pubitemid 40933051)
    • (2005) Current Vascular Pharmacology , vol.3 , Issue.3 , pp. 293-299
    • Evgenov, O.V.1    Liaudet, L.2
  • 14
    • 0035851210 scopus 로고    scopus 로고
    • Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase
    • F.G. Soriano, P. Pacher, J. Mabley, L. Liaudet, and C. Szabo Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase Circ. Res. 89 2001 684 691 (Pubitemid 34627068)
    • (2001) Circulation Research , vol.89 , Issue.8 , pp. 684-691
    • Soriano, F.G.1    Pacher, P.2    Mabley, J.3    Liaudet, L.4    Szabo, C.5
  • 15
    • 79955479655 scopus 로고    scopus 로고
    • PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: Correlation with peripheral nerve function
    • S. Lupachyk, H. Shevalye, Y. Maksimchyk, V.R. Drel, and I.G. Obrosova PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function Free Radic. Biol. Med. 50 2011 1400 1409
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 1400-1409
    • Lupachyk, S.1    Shevalye, H.2    Maksimchyk, Y.3    Drel, V.R.4    Obrosova, I.G.5
  • 16
    • 77956649770 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease
    • H. Shevalye, Y. Maksimchyk, P. Watcho, and I.G. Obrosova Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease Biochim. Biophys. Acta 1802 2010 1020 1027
    • (2010) Biochim. Biophys. Acta , vol.1802 , pp. 1020-1027
    • Shevalye, H.1    Maksimchyk, Y.2    Watcho, P.3    Obrosova, I.G.4
  • 20
    • 0036064154 scopus 로고    scopus 로고
    • The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes
    • P. Pacher, L. Liaudet, F.G. Soriano, J.G. Mabley, E. Szabo, and C. Szabo The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes Diabetes 51 2002 514 521 (Pubitemid 34764811)
    • (2002) Diabetes , vol.51 , Issue.2 , pp. 514-521
    • Pacher, P.1    Liaudet, L.2    Soriano, F.G.3    Mabley, J.G.4    Szabo, E.5    Szabo, C.6
  • 21
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • DOI 10.1152/physrev.00029.2006
    • P. Pacher, J.S. Beckman, and L. Liaudet Nitric oxide and peroxynitrite in health and disease Physiol. Rev. 87 2007 315 424 (Pubitemid 46217686)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 28
    • 79953240108 scopus 로고    scopus 로고
    • MYC, PARP1, and chemoresistance: BIN there, done that?
    • S. Ganesan MYC, PARP1, and chemoresistance: BIN there, done that? Sci. Signal. 4 2011 pe15
    • (2011) Sci. Signal. , vol.4 , pp. 15
    • Ganesan, S.1
  • 29
    • 79953251340 scopus 로고    scopus 로고
    • C-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: A mechanism by which cancer cells acquire cisplatin resistance
    • S. Pyndiah, S. Tanida, K.M. Ahmed, E.K. Cassimere, C. Choe, and D. Sakamuro c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance Sci. Signal. 4 2011 ra19
    • (2011) Sci. Signal. , vol.4 , pp. 19
    • Pyndiah, S.1    Tanida, S.2    Ahmed, K.M.3    Cassimere, E.K.4    Choe, C.5    Sakamuro, D.6
  • 30
    • 77957555168 scopus 로고    scopus 로고
    • Synergistic chemosensitivity of triple-negative breast cancer cell lines to poly(ADP-ribose) polymerase inhibition, gemcitabine, and cisplatin
    • K. Hastak, E. Alli, and J.M. Ford Synergistic chemosensitivity of triple-negative breast cancer cell lines to poly(ADP-ribose) polymerase inhibition, gemcitabine, and cisplatin Cancer Res. 70 2010 7970 7980
    • (2010) Cancer Res. , vol.70 , pp. 7970-7980
    • Hastak, K.1    Alli, E.2    Ford, J.M.3
  • 31
    • 75149194886 scopus 로고    scopus 로고
    • Renal dendritic cells ameliorate nephrotoxic acute kidney injury
    • R.K. Tadagavadi, and W.B. Reeves Renal dendritic cells ameliorate nephrotoxic acute kidney injury J. Am. Soc. Nephrol. 21 2010 53 63
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 53-63
    • Tadagavadi, R.K.1    Reeves, W.B.2
  • 33
    • 67651124846 scopus 로고    scopus 로고
    • Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice
    • M. Liu, D.N. Grigoryev, M.T. Crow, M. Haas, M. Yamamoto, S.P. Reddy, and H. Rabb Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice Kidney Int. 76 2009 277 285
    • (2009) Kidney Int. , vol.76 , pp. 277-285
    • Liu, M.1    Grigoryev, D.N.2    Crow, M.T.3    Haas, M.4    Yamamoto, M.5    Reddy, S.P.6    Rabb, H.7
  • 34
    • 78049500964 scopus 로고    scopus 로고
    • Endogenous IL-10 attenuates cisplatin nephrotoxicity: Role of dendritic cells
    • R.K. Tadagavadi, and W.B. Reeves Endogenous IL-10 attenuates cisplatin nephrotoxicity: role of dendritic cells J. Immunol. 185 2010 4904 4911
    • (2010) J. Immunol. , vol.185 , pp. 4904-4911
    • Tadagavadi, R.K.1    Reeves, W.B.2
  • 36
    • 66449121454 scopus 로고    scopus 로고
    • Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
    • C. Brooks, Q. Wei, S.G. Cho, and Z. Dong Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models J. Clin. Invest. 119 2009 1275 1285
    • (2009) J. Clin. Invest. , vol.119 , pp. 1275-1285
    • Brooks, C.1    Wei, Q.2    Cho, S.G.3    Dong, Z.4
  • 38
    • 67449095329 scopus 로고    scopus 로고
    • Functional TauT protects against acute kidney injury
    • X. Han, J. Yue, and R.W. Chesney Functional TauT protects against acute kidney injury J. Am. Soc. Nephrol. 20 2009 1323 1332
    • (2009) J. Am. Soc. Nephrol. , vol.20 , pp. 1323-1332
    • Han, X.1    Yue, J.2    Chesney, R.W.3
  • 39
    • 44049103058 scopus 로고    scopus 로고
    • TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity
    • B. Zhang, G. Ramesh, S. Uematsu, S. Akira, and W.B. Reeves TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity J. Am. Soc. Nephrol. 19 2008 923 932
    • (2008) J. Am. Soc. Nephrol. , vol.19 , pp. 923-932
    • Zhang, B.1    Ramesh, G.2    Uematsu, S.3    Akira, S.4    Reeves, W.B.5
  • 41
    • 34248178529 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: Effects on macrophage recruitment, nuclear factor-κB nuclear translocation, and foam cell death
    • DOI 10.1161/CIRCULATIONAHA.106.668756
    • K. Oumouna-Benachour, C.P. Hans, Y. Suzuki, A. Naura, R. Datta, S. Belmadani, K. Fallon, C. Woods, and A.H. Boulares Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death Circulation 115 2007 2442 2450 (Pubitemid 46717967)
    • (2007) Circulation , vol.115 , Issue.18 , pp. 2442-2450
    • Oumouna-Benachour, K.1    Hans, C.P.2    Suzuki, Y.3    Naura, A.4    Datta, R.5    Belmadani, S.6    Fallon, K.7    Woods, C.8    Boulares, A.H.9
  • 43
    • 38349158077 scopus 로고    scopus 로고
    • Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy
    • DOI 10.1038/nprot.2007.327, PII NPROT.2007.327
    • P. Mukhopadhyay, M. Rajesh, G. Hasko, B.J. Hawkins, M. Madesh, and P. Pacher Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy Nat. Protoc. 2 2007 2295 2301 (Pubitemid 351565867)
    • (2007) Nature Protocols , vol.2 , Issue.9 , pp. 2295-2301
    • Mukhopadhyay, P.1    Rajesh, M.2    Hasko, G.3    Hawkins, B.J.4    Madesh, M.5    Pacher, P.6
  • 45
    • 0032127666 scopus 로고    scopus 로고
    • Role of poly(ADP-ribose) synthetase in inflammation and ischaemia- reperfusion
    • DOI 10.1016/S0165-6147(98)01193-6
    • C. Szabo, and V.L. Dawson Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion Trends Pharmacol. Sci. 19 1998 287 298 (Pubitemid 28358088)
    • (1998) Trends in Pharmacological Sciences , vol.19 , Issue.7 , pp. 287-298
    • Szabo, C.1    Dawson, V.L.2
  • 46
    • 3342933276 scopus 로고    scopus 로고
    • Introduction to serial reviews on 4-hydroxy-2-nonenal as a signaling molecule
    • DOI 10.1016/j.freeradbiomed.2004.06.009, PII S0891584904004629
    • H.J. Forman, and D.A. Dickinson Introduction to serial reviews on 4-hydroxy-2-nonenal as a signaling molecule Free Radic. Biol. Med. 37 2004 594 596 (Pubitemid 38993507)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.5 , pp. 594-596
    • Forman, H.J.1    Dickinson, D.A.2
  • 47
    • 50949103793 scopus 로고    scopus 로고
    • The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal
    • H.J. Forman, J.M. Fukuto, T. Miller, H. Zhang, A. Rinna, and S. Levy The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal Arch. Biochem. Biophys. 477 2008 183 195
    • (2008) Arch. Biochem. Biophys. , vol.477 , pp. 183-195
    • Forman, H.J.1    Fukuto, J.M.2    Miller, T.3    Zhang, H.4    Rinna, A.5    Levy, S.6
  • 49
    • 0022931584 scopus 로고
    • Hydroxyl free radical adduct of deoxyguanosine: Sensitive detection and mechanisms of formation
    • R.A. Floyd, J.J. Watson, P.K. Wong, D.H. Altmiller, and R.C. Rickard Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation Free Radic. Res. Commun. 1 1986 163 172
    • (1986) Free Radic. Res. Commun. , vol.1 , pp. 163-172
    • Floyd, R.A.1    Watson, J.J.2    Wong, P.K.3    Altmiller, D.H.4    Rickard, R.C.5
  • 50
    • 0022518237 scopus 로고
    • Formation of 8-hydroxydeoxyguanosine, hydroxyl free radical adduct of DNA in granulocytes exposed to the tumor promoter, tetradeconylphorbolacetate
    • R.A. Floyd, J.J. Watson, J. Harris, M. West, and P.K. Wong Formation of 8-hydroxydeoxyguanosine, hydroxyl free radical adduct of DNA in granulocytes exposed to the tumor promoter, tetradecanoylphorbolacetate Biochem. Biophys. Res. Commun. 137 1986 841 846 (Pubitemid 16044464)
    • (1986) Biochemical and Biophysical Research Communications , vol.137 , Issue.2 , pp. 841-846
    • Floyd, R.A.1    Watson, J.J.2    Harris, J.3
  • 51
    • 0025045198 scopus 로고
    • The role of 8-hydroxyguanine in carcinogenesis
    • R.A. Floyd The role of 8-hydroxyguanine in carcinogenesis Carcinogenesis 11 1990 1447 1450 (Pubitemid 20281454)
    • (1990) Carcinogenesis , vol.11 , Issue.9 , pp. 1447-1450
    • Floyd, R.A.1
  • 52
    • 0026577281 scopus 로고
    • Lipid peroxidation products mediate the formation of 8- hydroxydeoxyguanosine in DNA
    • J.W. Park, and R.A. Floyd Lipid peroxidation products mediate the formation of 8-hydroxydeoxyguanosine in DNA Free Radic. Biol. Med. 12 1992 245 250
    • (1992) Free Radic. Biol. Med. , vol.12 , pp. 245-250
    • Park, J.W.1    Floyd, R.A.2
  • 53
    • 0028369212 scopus 로고
    • 8-Hydroxydeoxyguanosine in DNA from TPA-stimulated human granulocytes
    • H.C. Birnboim, L. Maidt, T. Raynor, and R.A. Floyd 8- Hydroxydeoxyguanosine in DNA from TPA-stimulated human granulocytes Free Radic. Res. 20 1994 113 117 (Pubitemid 2051922)
    • (1994) Free Radical Research , vol.20 , Issue.2 , pp. 113-117
    • Birnboim, H.C.1    Maidt, L.2    Raynor, T.3    Floyd, R.A.4
  • 55
    • 0032556905 scopus 로고    scopus 로고
    • Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
    • DOI 10.1038/34923
    • J.P. Eiserich, M. Hristova, C.E. Cross, A.D. Jones, B.A. Freeman, B. Halliwell, and A. van der Vliet Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils Nature 391 1998 393 397 (Pubitemid 28093514)
    • (1998) Nature , vol.391 , Issue.6665 , pp. 393-397
    • Eiserich, J.P.1    Hristova, M.2    Cross, C.E.3    Jones, A.D.4    Freeman, B.A.5    Halliwell, B.6    Van Der Vliet, A.7
  • 57
    • 0344196903 scopus 로고    scopus 로고
    • NO-dependent protein nitration: A cell signaling event or an oxidative inflammatory response?
    • DOI 10.1016/j.tibs.2003.10.006
    • F.J. Schopfer, P.R. Baker, and B.A. Freeman NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response? Trends Biochem. Sci. 28 2003 646 654 (Pubitemid 37500899)
    • (2003) Trends in Biochemical Sciences , vol.28 , Issue.12 , pp. 646-654
    • Schopfer, F.J.1    Baker, P.R.S.2    Freeman, B.A.3
  • 58
    • 34547673497 scopus 로고    scopus 로고
    • Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
    • DOI 10.1038/nrd2222, PII NRD2222
    • C. Szabo, H. Ischiropoulos, and R. Radi Peroxynitrite: biochemistry, pathophysiology and development of therapeutics Nat. Rev. Drug Discov. 6 2007 662 680 (Pubitemid 47207751)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.8 , pp. 662-680
    • Szabo, C.1    Ischiropoulos, H.2    Radi, R.3
  • 59
    • 79953040755 scopus 로고    scopus 로고
    • The poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide suppresses cell growth and migration, enhancing suppressive effects of cisplatin in osteosarcoma cells
    • Y.D. Zheng, X.Q. Xu, F. Peng, J.Z. Yu, and H. Wu The poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide suppresses cell growth and migration, enhancing suppressive effects of cisplatin in osteosarcoma cells Oncol. Rep. 25 2011 1399 1405
    • (2011) Oncol. Rep. , vol.25 , pp. 1399-1405
    • Zheng, Y.D.1    Xu, X.Q.2    Peng, F.3    Yu, J.Z.4    Wu, H.5
  • 62
    • 79956195555 scopus 로고    scopus 로고
    • Novel agents and future directions for refractory breast cancer
    • H.J. Burstein Novel agents and future directions for refractory breast cancer Semin. Oncol. 38 Suppl. 2 2011 S17 S24
    • (2011) Semin. Oncol. , vol.38 , Issue.SUPPL. 2
    • Burstein, H.J.1
  • 63
    • 79251564088 scopus 로고    scopus 로고
    • A review of PARP inhibitors: From bench to bedside
    • C. Underhill, M. Toulmonde, and H. Bonnefoi A review of PARP inhibitors: from bench to bedside Ann. Oncol. 22 2011 268 279
    • (2011) Ann. Oncol. , vol.22 , pp. 268-279
    • Underhill, C.1    Toulmonde, M.2    Bonnefoi, H.3
  • 64
    • 79551652531 scopus 로고    scopus 로고
    • The clinical development of inhibitors of poly(ADP-ribose) polymerase
    • H. Calvert, and A. Azzariti The clinical development of inhibitors of poly(ADP-ribose) polymerase Ann. Oncol. 22 Suppl. 1 2011 i53 i59
    • (2011) Ann. Oncol. , vol.22 , Issue.SUPPL. 1
    • Calvert, H.1    Azzariti, A.2
  • 65
    • 19444362951 scopus 로고    scopus 로고
    • Clinical perspectives of PARP inhibitors
    • DOI 10.1016/j.phrs.2005.02.013, PII S1043661805000460
    • G. Graziani, and C. Szabo Clinical perspectives of PARP inhibitors Pharmacol. Res. 52 2005 109 118 (Pubitemid 40725605)
    • (2005) Pharmacological Research , vol.52 , Issue.1 SPEC. ISS. , pp. 109-118
    • Graziani, G.1    Szabo, C.2
  • 66
    • 36849017995 scopus 로고    scopus 로고
    • Clinical poly(ADP-ribose) polymerase inhibitors for the treatment of cancer
    • C. Lewis, and J.A. Low Clinical poly(ADP-ribose) polymerase inhibitors for the treatment of cancer Curr. Opin. Investig. Drugs 8 2007 1051 1056 (Pubitemid 350224330)
    • (2007) Current Opinion in Investigational Drugs , vol.8 , Issue.12 , pp. 1051-1056
    • Lewis, C.1    Low, J.A.2
  • 67
    • 78649601369 scopus 로고    scopus 로고
    • How to kill tumor cells with inhibitors of poly(ADP-ribosyl)ation
    • A. Mangerich, and A. Burkle How to kill tumor cells with inhibitors of poly(ADP-ribosyl)ation Int. J. Cancer 128 2011 251 265
    • (2011) Int. J. Cancer , vol.128 , pp. 251-265
    • Mangerich, A.1    Burkle, A.2
  • 69
    • 62449330864 scopus 로고    scopus 로고
    • Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death
    • H. Pan, P. Mukhopadhyay, M. Rajesh, V. Patel, B. Mukhopadhyay, B. Gao, G. Hasko, and P. Pacher Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death J. Pharmacol. Exp. Ther. 328 2009 708 714
    • (2009) J. Pharmacol. Exp. Ther. , vol.328 , pp. 708-714
    • Pan, H.1    Mukhopadhyay, P.2    Rajesh, M.3    Patel, V.4    Mukhopadhyay, B.5    Gao, B.6    Hasko, G.7    Pacher, P.8
  • 71
    • 0026453418 scopus 로고
    • Peroxynitrite formation from macrophage-derived nitric oxide
    • H. Ischiropoulos, L. Zhu, and J.S. Beckman Peroxynitrite formation from macrophage-derived nitric oxide Arch. Biochem. Biophys. 298 1992 446 451
    • (1992) Arch. Biochem. Biophys. , vol.298 , pp. 446-451
    • Ischiropoulos, H.1    Zhu, L.2    Beckman, J.S.3
  • 72
    • 4644324913 scopus 로고    scopus 로고
    • Inflammatory cytokines in acute renal failure
    • G. Ramesh, and W.B. Reeves Inflammatory cytokines in acute renal failure Kidney Int. Suppl. 91 2004 S56 S61
    • (2004) Kidney Int. Suppl. , Issue.91
    • Ramesh, G.1    Reeves, W.B.2
  • 73
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
    • R. Radi, J.S. Beckman, K.M. Bush, and B.A. Freeman Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide Arch. Biochem. Biophys. 288 1991 481 487
    • (1991) Arch. Biochem. Biophys. , vol.288 , pp. 481-487
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 76
    • 0037067317 scopus 로고    scopus 로고
    • Mediation of poty(ADP-ribose) polymerase-1 - Dependent cell death by apoptosis-inducing factor
    • DOI 10.1126/science.1072221
    • S.W. Yu, H. Wang, M.F. Poitras, C. Coombs, W.J. Bowers, H.J. Federoff, G.G. Poirier, T.M. Dawson, and V.L. Dawson Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor Science 297 2002 259 263 (Pubitemid 34761289)
    • (2002) Science , vol.297 , Issue.5579 , pp. 259-263
    • Yu, S.-W.1    Wang, H.2    Poitras, M.F.3    Coombs, C.4    Bowers, W.J.5    Federoff, H.J.6    Poirier, G.G.7    Dawson, T.M.8    Dawson, V.L.9
  • 80
    • 1142285446 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase activation in the reperfused myocardium
    • DOI 10.1016/j.cardiores.2003.09.029
    • G. Szabo, L. Liaudet, S. Hagl, and C. Szabo Poly(ADP-ribose) polymerase activation in the reperfused myocardium Cardiovasc. Res. 61 2004 471 480 (Pubitemid 38210153)
    • (2004) Cardiovascular Research , vol.61 , Issue.3 , pp. 471-480
    • Szabo, G.1    Liaudet, L.2    Hagl, S.3    Szabo, C.4
  • 82
    • 13244278121 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation
    • DOI 10.1016/j.ejcts.2004.10.055, PII S1010794004007778
    • G. Szabo, P. Soos, U. Heger, C. Flechtenmacher, S. Bahrle, Z. Zsengeller, C. Szabo, and S. Hagl Poly(ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation Eur. J. Cardiothorac. Surg. 27 2005 226 234 (Pubitemid 40193131)
    • (2005) European Journal of Cardio-thoracic Surgery , vol.27 , Issue.2 , pp. 226-234
    • Szabo, G.1    Soos, P.2    Heger, U.3    Flechtenmacher, C.4    Bahrle, S.5    Zsengeller, Z.6    Szabo, C.7    Hagl, S.8
  • 83
    • 0032514225 scopus 로고    scopus 로고
    • Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury
    • B. Zingarelli, A.L. Salzman, and C. Szabo Genetic disruption of poly(ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury Circ. Res. 83 1998 85 94 (Pubitemid 28322102)
    • (1998) Circulation Research , vol.83 , Issue.1 , pp. 85-94
    • Zingarelli, B.1    Salzman, A.L.2    Szabo, C.3
  • 84
    • 19444377566 scopus 로고    scopus 로고
    • Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications
    • DOI 10.1016/j.phrs.2005.02.015, PII S1043661805000484
    • C. Szabo Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications Pharmacol. Res. 52 2005 60 71 (Pubitemid 40725600)
    • (2005) Pharmacological Research , vol.52 , Issue.1 SPEC. ISS. , pp. 60-71
    • Szabo, C.1
  • 85
    • 7044229731 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-κB
    • DOI 10.2337/diabetes.53.11.2960
    • L. Zheng, C. Szabo, and T.S. Kern Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB Diabetes 53 2004 2960 2967 (Pubitemid 39425922)
    • (2004) Diabetes , vol.53 , Issue.11 , pp. 2960-2967
    • Zheng, L.1    Szabo, C.2    Kern, T.S.3
  • 86
    • 0037137287 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity
    • DOI 10.1161/01.CIR.0000038365.78031.9C
    • C. Szabo, A. Zanchi, K. Komjati, P. Pacher, A.S. Krolewski, W.C. Quist, F.W. LoGerfo, E.S. Horton, and A. Veves Poly(ADP-ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity Circulation 106 2002 2680 2686 (Pubitemid 35364922)
    • (2002) Circulation , vol.106 , Issue.21 , pp. 2680-2686
    • Szabo, C.1    Zanchi, A.2    Komjati, K.3    Pacher, P.4    Krolewski, A.S.5    Quist, W.C.6    LoGerfo, F.W.7    Horton, E.S.8    Veves, A.9
  • 89
    • 0030854951 scopus 로고    scopus 로고
    • Endothelial dysfunction in a rat model of endotoxic shock: Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite
    • C. Szabo, S. Cuzzocrea, B. Zingarelli, M. O'Connor, and A.L. Salzman Endothelial dysfunction in a rat model of endotoxic shock: importance of the activation of poly(ADP-ribose) synthetase by peroxynitrite J. Clin. Invest. 100 1997 723 735 (Pubitemid 27340522)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.3 , pp. 723-735
    • Szabo, C.1    Cuzzocrea, S.2    Zingarelli, B.3    O'Connor, M.4    Salzman, A.L.5
  • 90
    • 0032059832 scopus 로고    scopus 로고
    • Potential role of the peroxynitrite-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock
    • C. Szabo Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock Shock 9 1998 341 344 (Pubitemid 128463882)
    • (1998) Shock , vol.9 , Issue.5 , pp. 341-344
    • Szabo, C.1
  • 91
    • 0032196891 scopus 로고    scopus 로고
    • 3-Aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, improves hemodynamics and prolongs survival in a porcine model of hemorrhagic shock
    • A. Szabo, P. Hake, A.L. Salzman, and C. Szabo 3-Aminobenzamide, an inhibitor of poly(ADP-ribose) synthetase, improves hemodynamics and prolongs survival in a porcine model of hemorrhagic shock Shock 10 1998 347 353 (Pubitemid 128463273)
    • (1998) Shock , vol.10 , Issue.5 , pp. 347-353
    • Szabo, A.1    Hake, P.2    Salzman, A.L.3    Szabo, C.4
  • 92
    • 0029934194 scopus 로고    scopus 로고
    • Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite
    • C. Szabo, B. Zingarelli, and A.L. Salzman Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite Circ. Res. 78 1996 1051 1063 (Pubitemid 26168580)
    • (1996) Circulation Research , vol.78 , Issue.6 , pp. 1051-1063
    • Szabo, C.1    Zingarelli, B.2    Salzman, A.L.3
  • 94
    • 14344266084 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase promotes cardiac remodeling, contractile failure, and translocation of apoptosis-inducing factor in a murine experimental model of aortic banding and heart failure
    • DOI 10.1124/jpet.104.077164
    • C.Y. Xiao, M. Chen, Z. Zsengeller, H. Li, L. Kiss, M. Kollai, and C. Szabo Poly(ADP-ribose) polymerase promotes cardiac remodeling, contractile failure, and translocation of apoptosis-inducing factor in a murine experimental model of aortic banding and heart failure J. Pharmacol. Exp. Ther. 312 2005 891 898 (Pubitemid 40293746)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.312 , Issue.3 , pp. 891-898
    • Xiao, C.-Y.1    Chen, M.2    Zsengeller, Z.3    Li, H.4    Kiss, L.5    Kollai, M.6    Szabo, C.7
  • 95
    • 0037448784 scopus 로고    scopus 로고
    • Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction
    • DOI 10.1161/01.CIR.0000048192.52098.DD
    • P. Pacher, L. Liaudet, P. Bai, J.G. Mabley, P.M. Kaminski, L. Virag, A. Deb, E. Szabo, Z. Ungvari, M.S. Wolin, J.T. Groves, and C. Szabo Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction Circulation 107 2003 896 904 (Pubitemid 36241050)
    • (2003) Circulation , vol.107 , Issue.6 , pp. 896-904
    • Pacher, P.1    Liaudet, L.2    Bai, P.3    Mabley, J.G.4    Kaminski, P.M.5    Virag, L.6    Deb, A.7    Szabo, E.8    Ungvari, Z.9    Wolin, M.S.10    Groves, J.T.11    Szabo, C.12
  • 98
    • 0037019589 scopus 로고    scopus 로고
    • Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure
    • DOI 10.1016/S0735-1097(02)02062-4, PII S0735109702020624
    • P. Pacher, L. Liaudet, J. Mabley, K. Komjati, and C. Szabo Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure J. Am. Coll. Cardiol. 40 2002 1006 1016 (Pubitemid 34994999)
    • (2002) Journal of the American College of Cardiology , vol.40 , Issue.5 , pp. 1006-1016
    • Pacher, P.1    Liaudet, L.2    Mabley, J.G.3    Komjati, K.4    Szabo, C.5
  • 99
    • 33644861815 scopus 로고    scopus 로고
    • Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure
    • P. Pacher, L. Liaudet, J.G. Mabley, A. Cziraki, G. Hasko, and C. Szabo Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure Int. J. Mol. Med. 17 2006 369 375
    • (2006) Int. J. Mol. Med. , vol.17 , pp. 369-375
    • Pacher, P.1    Liaudet, L.2    Mabley, J.G.3    Cziraki, A.4    Hasko, G.5    Szabo, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.