-
1
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virag L, Szabo C. (2002) The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol. Rev. 54:375-429.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabo, C.2
-
2
-
-
0036710459
-
The functional role of poly(ADP-ribose) polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders
-
Hassa PO, Hottiger MO. (2002) The functional role of poly(ADP-ribose) polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders. Cell. Mol. Life Sci. 59:1534-53.
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, pp. 1534-1553
-
-
Hassa, P.O.1
Hottiger, M.O.2
-
3
-
-
0032990560
-
Endothelial dysfunction in human disease
-
Drexler H, Harnig B. (1999) Endothelial dysfunction in human disease. J. Mol. Cell. Cardiol. 31:51-60.
-
(1999)
J. Mol. Cell. Cardiol.
, vol.31
, pp. 51-60
-
-
Drexler, H.1
Harnig, B.2
-
4
-
-
0034167908
-
Free radical production and angiotensin
-
Wolf G. (2000) Free radical production and angiotensin. Curr. Hypertens. Rep. 2:167-73.
-
(2000)
Curr. Hypertens. Rep.
, vol.2
, pp. 167-173
-
-
Wolf, G.1
-
5
-
-
0037673081
-
Interactions between the renin-angiotensin system and dyslipidemia: Relevance in the therapy of hypertension and coronary heart disease
-
Singh BM, Mehta JL. (2003) Interactions between the renin-angiotensin system and dyslipidemia: relevance in the therapy of hypertension and coronary heart disease. Arch. Intern. Med. 163:1296-304.
-
(2003)
Arch. Intern. Med.
, vol.163
, pp. 1296-1304
-
-
Singh, B.M.1
Mehta, J.L.2
-
6
-
-
0042134568
-
The renin-angiotensin system and the long-term complications of diabetes: Pathophysiological and therapeutic considerations
-
Gilbert RE, Krum H, Wilkinson-Berka J, Kelly DJ. (2003) The renin-angiotensin system and the long-term complications of diabetes: pathophysiological and therapeutic considerations. Diabet. Med. 20:607-21.
-
(2003)
Diabet. Med.
, vol.20
, pp. 607-621
-
-
Gilbert, R.E.1
Krum, H.2
Wilkinson-Berka, J.3
Kelly, D.J.4
-
7
-
-
0031041547
-
Role of superoxide in angiotensin II-induced but not catecholamine- induced hypertension
-
Laursen JB, Rajagopalan S, Galis Z, Tarpey M, Freeman BA, Harrison DG. (1997) Role of superoxide in angiotensin II-induced but not catecholamine- induced hypertension. Circulation 95:588-93.
-
(1997)
Circulation
, vol.95
, pp. 588-593
-
-
Laursen, J.B.1
Rajagopalan, S.2
Galis, Z.3
Tarpey, M.4
Freeman, B.A.5
Harrison, D.G.6
-
8
-
-
0142151745
-
Role of oxidative stress in endothelial dysfunction and enhanced responses to angiotensin II of afferent arterioles from rabbits infused with angiotensin II
-
Wang D, Chen Y, Chabrashvili T, Aslam S, Barrego Candle LJ, Umans JG, Wilcox CS. (2003) Role of oxidative stress in endothelial dysfunction and enhanced responses to angiotensin II of afferent arterioles from rabbits infused with angiotensin II. J. Am. Soc. Nephrol. 14:2783-9.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 2783-2789
-
-
Wang, D.1
Chen, Y.2
Chabrashvili, T.3
Aslam, S.4
Barrego Candle, L.J.5
Umans, J.G.6
Wilcox, C.S.7
-
10
-
-
0036792751
-
Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II
-
Landmesser U, Cai H, Dikalov S, McCann L, Hwang J, Jo H, Holland SM, Harrison DG. (2002) Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II. Hypertension 40:511-5.
-
(2002)
Hypertension
, vol.40
, pp. 511-515
-
-
Landmesser, U.1
Cai, H.2
Dikalov, S.3
McCann, L.4
Hwang, J.5
Jo, H.6
Holland, S.M.7
Harrison, D.G.8
-
11
-
-
0033966101
-
Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders
-
Wattanapitayakul SK, Weinstein DM, Holycross BJ, Bauer JA. (2000) Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders. FASEB J. 14:271-8.
-
(2000)
FASEB J.
, vol.14
, pp. 271-278
-
-
Wattanapitayakul, S.K.1
Weinstein, D.M.2
Holycross, B.J.3
Bauer, J.A.4
-
12
-
-
0345268767
-
Effects of angiotensin II on vascular endothelial cells: Formation of receptor-mediated reactive nitrogen species
-
Mihm MJ, Wattanapitayakul SK, Piao SF, Hoyt DG, Bauer JA. (2003) Effects of angiotensin II on vascular endothelial cells: formation of receptor-mediated reactive nitrogen species. Biochem. Pharmacol. 65:1189-97.
-
(2003)
Biochem. Pharmacol.
, vol.65
, pp. 1189-1197
-
-
Mihm, M.J.1
Wattanapitayakul, S.K.2
Piao, S.F.3
Hoyt, D.G.4
Bauer, J.A.5
-
13
-
-
17144447467
-
Novel phenanthridinone inhibitors of poly (adenosine 5′- diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents
-
Jagtap P et al. (2002) Novel phenanthridinone inhibitors of poly (adenosine 5′-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents. Crit. Care Med. 30:1071-82.
-
(2002)
Crit. Care Med.
, vol.30
, pp. 1071-1082
-
-
Jagtap, P.1
-
14
-
-
0035136240
-
Diabetic endothelial dysfunction: The role of poly (ADP-ribose) polymerase activation
-
Garcia Soriano F et al. (2001) Diabetic endothelial dysfunction: the role of poly (ADP-ribose) polymerase activation. Nat. Med. 7:108-13.
-
(2001)
Nat. Med.
, vol.7
, pp. 108-113
-
-
Garcia Soriano, F.1
-
15
-
-
17044456663
-
Effect of poly (ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep
-
Shimoda K et al. (2003) Effect of poly (ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep. Am. J. Physiol. Lung Cell. Mol. Physiol. 285:240-9.
-
(2003)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.285
, pp. 240-249
-
-
Shimoda, K.1
-
16
-
-
0042166004
-
Poly (ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass
-
Khan TA et al. (2003) Poly (ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass. J. Am. Coll. Surg. 197:270-7.
-
(2003)
J. Am. Coll. Surg.
, vol.197
, pp. 270-277
-
-
Khan, T.A.1
-
17
-
-
0037019589
-
Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure
-
Pacher P, Liaudet L, Mabley J, Komjati K, Szabo C. (2002) Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure. J. Am. Coll. Cardiol. 40:1006-16.
-
(2002)
J. Am. Coll. Cardiol.
, vol.40
, pp. 1006-1016
-
-
Pacher, P.1
Liaudet, L.2
Mabley, J.3
Komjati, K.4
Szabo, C.5
-
18
-
-
0037448784
-
Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction
-
Pacher P et al. (2003) Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction. Circulation 107:896-904.
-
(2003)
Circulation
, vol.107
, pp. 896-904
-
-
Pacher, P.1
-
19
-
-
0036615996
-
Activation of poly (ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging
-
Pacher P, Mabley JG, Soriano FG, Liaudet L, Szabo C. (2002) Activation of poly (ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging. Int. J. Mol. Med. 9:659-64.
-
(2002)
Int. J. Mol. Med.
, vol.9
, pp. 659-664
-
-
Pacher, P.1
Mabley, J.G.2
Soriano, F.G.3
Liaudet, L.4
Szabo, C.5
-
20
-
-
0030854951
-
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite
-
Szabo C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL. (1997) Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J. Clin. Invest. 100:723-35.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 723-735
-
-
Szabo, C.1
Cuzzocrea, S.2
Zingarelli, B.3
O'Connor, M.4
Salzman, A.L.5
-
21
-
-
0030788898
-
Beneficial effects of 3-aminobenzamide, an inhibitor of poly(ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion
-
Cuzzocrea S et al. (1997) Beneficial effects of 3-aminobenzamide, an inhibitor of poly(ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br. J. Pharmacol. 121:1065-74.
-
(1997)
Br. J. Pharmacol.
, vol.121
, pp. 1065-1074
-
-
Cuzzocrea, S.1
-
22
-
-
0035851210
-
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase
-
Soriano FG, Pacher P, Mabley J, Liaudet L, Szabo C. (2001) Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase. Circ. Res. 89:684-91.
-
(2001)
Circ. Res.
, vol.89
, pp. 684-691
-
-
Soriano, F.G.1
Pacher, P.2
Mabley, J.3
Liaudet, L.4
Szabo, C.5
-
23
-
-
0033215046
-
Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: Role of membrane-bound NADH-/NADPH-oxidases
-
Zhang H et al. (1999) Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH- oxidases. Cardiovasc. Res. 44:215-22.
-
(1999)
Cardiovasc. Res.
, vol.44
, pp. 215-222
-
-
Zhang, H.1
-
24
-
-
0034060298
-
Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress
-
Pueyo ME et al. (2000) Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress. Arterioscler. Thromb. Vasc. Biol. 20:645-51.
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
, pp. 645-651
-
-
Pueyo, M.E.1
-
25
-
-
0035096812
-
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes
-
Mervaala EM et al. (2001) Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes. Hypertension 37:414-8.
-
(2001)
Hypertension
, vol.37
, pp. 414-418
-
-
Mervaala, E.M.1
-
26
-
-
0037073677
-
NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II
-
Cai H et al. (2002) NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II. J. Biol. Chem. 277:48311-7.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48311-48317
-
-
Cai, H.1
-
27
-
-
0037040947
-
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling
-
Mollnau H et al. (2002) Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ. Res. 90:58-65.
-
(2002)
Circ. Res.
, vol.90
, pp. 58-65
-
-
Mollnau, H.1
-
28
-
-
0033774380
-
Renin-angiotensin system blockade improves endothelial dysfunction in hypertension
-
Goto K, Fujii K, Onaka U, Abe I, Fujishima M. (2000) Renin-angiotensin system blockade improves endothelial dysfunction in hypertension. Hypertension 36:575-80.
-
(2000)
Hypertension
, vol.36
, pp. 575-580
-
-
Goto, K.1
Fujii, K.2
Onaka, U.3
Abe, I.4
Fujishima, M.5
-
29
-
-
0036910690
-
Regression of ventricular and vascular hypertrophy: Are there differences between structurally different ACE inhibitors?
-
Raasch W et al. (2002) Regression of ventricular and vascular hypertrophy: are there differences between structurally different ACE inhibitors? J. Hypertens. 20:2495-504.
-
(2002)
J. Hypertens.
, vol.20
, pp. 2495-2504
-
-
Raasch, W.1
-
30
-
-
0043132430
-
Cardiac effects of amilaride and of enalapril in the spontaneously hypertensive rat
-
Ji Y, Huang Y, Han Y, Xu Y, Ferra A. (2003) Cardiac effects of amilaride and of enalapril in the spontaneously hypertensive rat. J Hypertens. 21:1583-9.
-
(2003)
J Hypertens.
, vol.21
, pp. 1583-1589
-
-
Ji, Y.1
Huang, Y.2
Han, Y.3
Xu, Y.4
Ferra, A.5
-
31
-
-
0032738983
-
Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase
-
Go YM et al. (1999) Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase. Am. J. Physiol. 277:1647-53.
-
(1999)
Am. J. Physiol.
, vol.277
, pp. 1647-1653
-
-
Go, Y.M.1
-
32
-
-
0035726286
-
Flow pulsatility is a critical determinant of oxidative stress in endothelial cells
-
Silacci P, Desgeorges A, Mazzolai L, Chambaz C, Hayoz D. (2001) Flow pulsatility is a critical determinant of oxidative stress in endothelial cells. Hypertension 38:1162-6.
-
(2001)
Hypertension
, vol.38
, pp. 1162-1166
-
-
Silacci, P.1
Desgeorges, A.2
Mazzolai, L.3
Chambaz, C.4
Hayoz, D.5
-
33
-
-
0037216768
-
Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase
-
Fleming I, Busse R. (2003) Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284:1-12.
-
(2003)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.284
, pp. 1-12
-
-
Fleming, I.1
Busse, R.2
-
34
-
-
0037009883
-
Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs
-
Tham DM et al. (2002) Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs. Physiol. Genomics 11:21-30.
-
(2002)
Physiol. Genomics
, vol.11
, pp. 21-30
-
-
Tham, D.M.1
-
35
-
-
0038300382
-
Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin
-
Castanza A et al. (2003) Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin. J. Cell. Physiol. 195:402-10.
-
(2003)
J. Cell. Physiol.
, vol.195
, pp. 402-410
-
-
Castanza, A.1
|