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Volumn 11, Issue 5, 2011, Pages 284-294

Total synthesis and functional analysis of non-ribosomal peptides

Author keywords

biological activity; ion channels; natural products; structure activity relationships; total synthesis

Indexed keywords

ANTILLATOXIN; BIOLOGICAL PRODUCT; CYCLOPEPTIDE; LIPOPEPTIDE; POLYTHEONAMIDE B; PROTEIN; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

EID: 80053571473     PISSN: 15278999     EISSN: 15280691     Source Type: Journal    
DOI: 10.1002/tcr.201100014     Document Type: Article
Times cited : (15)

References (66)
  • 21
    • 0033525466 scopus 로고    scopus 로고
    • The first proposed NMR-based structure (4S, 5R)-1 was revised to be (4R, 5R)-1 by Shioiri and co-workers through total syntheses of the isomers: (a), F. Yokokawa, H. Fujiwara, T. Shioiri, Tetrahedron Lett. 1999, 40, 1915
    • (1999) Tetrahedron Lett , vol.40 , pp. 1915
    • Yokokawa, F.1    Fujiwara, H.2    Shioiri, T.3
  • 25
    • 33749655377 scopus 로고    scopus 로고
    • total synthesis of (4S, 5S)- and (4R, 5R)-1: (e), K-C. Lee, T-P. Loh, Chem. Comm. 2006, 40, 4209.
    • (2006) Chem. Comm , vol.40 , pp. 4209
    • Lee, K.-C.1    Loh, T.-P.2
  • 28
    • 0033231630 scopus 로고    scopus 로고
    • Gerwick and Murray reported the extensive biological studies of antillatoxin as well as the SAR studies of (4S, 5S)-, (4S, 5R)-, (4R, 5S)- and (4R, 5R)-1. (a), F. W. Berman, W. H. Gerwick, T. F. Murray, Toxicon 1999, 37, 1645
    • (1999) Toxicon , vol.37 , pp. 1645
    • Berman, F.W.1    Gerwick, W.H.2    Murray, T.F.3
  • 41
    • 0003784282 scopus 로고    scopus 로고
    • The channel formation through β-helical conformation is known for a head-to-head dimer of a non-ribosomal pentadecapeptide antibiotic gramicidin A. The tubular structure of polytheonamide B is three times as long as that of gramicidin A. For a review, see: Gramicidin and related ion channel-forming peptides; Wiley & Sons, Chichester, 1999.
    • (1999) Gramicidin and Related Ion Channel-forming Peptides


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.