Synthetic ciguatoxins selectively activate Nav1.8-derived chimeric sodium channels expressed in HEK293 cells

Journal of Biological Chemistry

Volumn 284, Issue 12, 2009, Pages 7597-7605

  Yamaoka, Kaoru ^a,h   Inoue, Masayuki ^b   Miyazaki, Keisuke ^c   Hirama, Masahiro ^c   Kondo, Chie ^d   Kinoshita, Eiji ^e   Miyoshi, Hiroshi ^f   Seyama, Issei ^g  

^a HIROSHIMA INTERNATIONAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e HIROSHIMA UNIVERSITY   (Japan)

^f HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^g Hiroshima Jogakuin University   (Japan)

^h NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION KINETICS; ACTIVATION PROCESS; HEK293 CELLS; HIGH SENSITIVITY; HYPERPOLARIZATION; MOLECULAR DOMAINS; N-TERMINAL; NEUROLOGICAL SYMPTOMS; SODIUM CHANNEL; TRANSDUCING; WILD TYPES;

TOXIC MATERIALS;

SODIUM;

CIGUATOXIN; SODIUM CHANNEL; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.8; TETRODOTOXIN; UNCLASSIFIED DRUG; HYBRID PROTEIN; MUSCLE PROTEIN; NA(V)1.4 CHANNEL, HUMAN; NA(V)1.4 PROTEIN, RAT; NA(V)1.8 PROTEIN, RAT; NERVE PROTEIN; SENSORY NEURON SPECIFIC (SNS) SODIUM CHANNEL;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CIGUATERA; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; SODIUM CONDUCTANCE; SODIUM CURRENT; WILD TYPE; ANIMAL; CELL LINE; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR GENETICS; PEPTIDE MAPPING; PROTEIN TERTIARY STRUCTURE;

CIGUATERA;

ANIMALS; BASE SEQUENCE; CELL LINE; CIGUATERA POISONING; CIGUATOXINS; GENE EXPRESSION; HUMANS; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; NERVE TISSUE PROTEINS; PEPTIDE MAPPING; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS; SODIUM CHANNELS;

EID: 65549157995     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M806481200     Document Type: Article

References (39)

1. Yasumoto, T. (2001) Chem. Rec. 1, 228-242
2. Benoit, E., Legrand, A. M., and Dubois, J. M. (1986) Toxicon 24, 357-364
3. Strachan, L. C., Lewis, R. J., and Nicholson, G. M. (1999) J. Pharmacol. Exp. Ther. 288, 379-388
4. Trainer, V. L., Thomsen, W. J., Catterall, W. A., and Baden, D. G. (1991) Mol. Pharmacol. 40, 988-994
5. Trainer, V. L., Baden, D. G., and Catterall, W. A. (1994) J. Biol. Chem. 269, 19904-19909
6. Rush, A. M., Cummins, T. R., and Waxman, S. G. (2007) J. Physiol. (Lond.) 579, 1-14
7. Akopian, A. N., Sivilotti, L., and Wood, J. N. (1996) Nature 379, 257-262
8. Akopian, A. N., Souslova, V., England, S., Okuse, K., Ogata, N., Ure, J., Smith, A., Kerr, B. J., McMahon, S. B., Boyce, S., Hill, R., Stanfa, L. C., Dickenson, A. H., and Wood, J. N. (1999) Nat. Neurosci. 2, 541-548
9. Renganathan, M., Cummins, T. R., and Waxman, S. G. (2001) J. Neurophysiol. 86, 629-640
10. Lai, J., Gold, M. S., Kim, C. S., Bian, D., Ossipov, M. H., Hunter, J. C., and Porreca, F. (2002) Pain 95, 143-152
11. Jarvis, M. F., Honore, P., Shieh, C. C., Chapman, M., Joshi, S., Zhang, X. F., Kort, M., Carroll, W., Marron, B., Atkinson, R., Thomas, J., Liu, D., Krambis, M., Liu, Y., McGaraughty, S., Chu, K., Roeloffs, R., Zhong, C., Mikusa, J. P., Hernandez, G., Gauvin, D., Wade, C., Zhu, C., Pai, M., Scanio, M., Shi, L., Drizin, I., Gregg, R., Matulenko, M., Hakeem, A., Gross, M., Johnson, M., Marsh, K., Wagoner, P. K., Sullivan, J. P., Faltynek, C. R., and Krafte, D. S. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 8520-8525
12. Trimmer, J. S., Cooperman, S. S., Tomiko, S. A., Zhou, J. Y., Crean, S. M., Boyle, M. B., Kallen, R. G., Sheng, Z. H., Barchi, R. L., Sigworth, F. J., Goodman, R. G., Agnew, S. A., and Mandel, G. (1989) Neuron 3, 33-49
13. Noda, M., Ikeda, T., Kayano, T., Suzuki, H., Takeshima, H., Kurasaki, M., Takahashi, H., and Numa, S. (1986) Nature 320, 188-192
14. Moriyoshi, K., Richards, L. J., Akazawa, C., O'Leary, D. D., and Nakanishi, S. (1996) Neuron 16, 255-260
15. Hong, S., Morrow, T. J., Paulson, P. E., Isom, L. L., and Wiley, J. W. (2004) J. Biol. Chem. 279, 29341-29350
16. John, V. H., Main, M. J., Powell, A. J., Gladwell, Z. M., Hick, C., Sidhu, H. S., Clare, J. J., Tate, S., and Trezise, D. J. (2004) Neuropharmacology 46, 425-438
17. Okuse, K., Malik-Hall, M., Baker, M. D., Poon, W. Y., Kong, H., Chao, M. V., and Wood, J. N. (2002) Nature 417, 653-656
18. Hirama, M., Oishi, T., Uehara, H., Inoue, M., Maruyama, M., Oguri, H., and Satake, M. (2001) Science 294, 1904-1907
19. Inoue, M., Miyazaki, K., Uehara, H., Maruyama, M., and Hirama, M. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 12013-12018
20. Inoue, M., Miyazaki, K., Ishihara, Y., Tatami, A., Ohnuma, Y., Kawada, Y., Komano, K., Yamashita, S., Lee, N., and Hirama, M. (2006) J. Am. Chem. Soc. 128, 9352-9354
21. Yamaoka, K., Inoue, M., Miyahara, H., Miyazaki, K., and Hirama, M. (2004) Br. J. Pharmacol. 142, 879-889
22. Armstrong, C. M., and Bezanilla, F. (1974) J. Gen. Physiol. 63, 533-552
23. Dunn, P. M., Coote, P. R., Wood, J. N., Burgess, G. M., and Rang, H. P. (1991) Brain Res. 545, 80-86
24. Kerr, B. J., Souslova, V., McMahon, S. B., and Wood, J. N. (2001) Neuroreport 12, 3077-3080
25. Laird, J. M., Souslova, V., Wood, J. N., and Cervero, F. (2002) J. Neurosci. 22, 8352-8356
26. Roza, C., Laird, J. M., Souslova, V., Wood, J. N., and Cervero, F. (2003) J. Physiol. (Lond.) 550, 921-926
27. Gold, M. S., Weinreich, D., Kim, C. S., Wang, R., Treanor, J., Porreca, F., and Lai, J. (2003) J. Neurosci. 23, 158-166
28. Khasar, S. G., Gold, M. S., and Levine, J. D. (1998) Neurosci. Lett. 256, 17-20
29. Porreca, F., Lai, J., Bian, D., Wegert, S., Ossipov, M. H., Eglen, R. M., Kassotakis, L., Novakovic, S., Rabert, D. K., Sangameswaran, L., and Hunter, J. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7640-7644
30. Yoshimura, N., Seki, S., Erickson, V., Erickson, K., Kassotakis, L., Novakovic, S., Fraser, M. O., Chancellor, M. B., and de Groat, W. C. (2001) Urology 57, 116-117
31. Toledo-Aral, J. J., Moss, B. L., He, Z. J., Koszowski, A. G., Whisenand, T., Levinson, S. R., Wolf, J. J., Silos-Santiago, I., Halegoua, S., and Mandel, G. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1527-1532
32. Nassar, M. A., Stirling, L. C., Forlani, G., Baker, M. D., Matthews, E. A., Dickenson, A. H., and Wood, J. N. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 12706-12711
33. Yang, Y., Wang, Y., Li, S., Xu, Z., Li, H., Ma, L., Fan, J., Bu, D., Liu, B., Fan, Z., Wu, G., Jin, J., Ding, B., Zhu, X., and Shen, Y. (2004) J. Med. Genet. 41, 171-174
34. Black, J. A., Liu, S., Tanaka, M., Cummins, T. R., and Waxman, S. G. (2004) Pain 108, 237-247
35. Tanaka, M., Cummins, T. R., Ishikawa, K., Dib-Hajj, S. D., Black, J. A., and Waxman, S. G. (1998) Neuroreport 9, 967-972
36. Cardenas, L. M., Cardenas, C. G., and Scroggs, R. S. (2001) J. Neurophysiol. 86, 241-248
37. Gold, M. S., Reichling, D. B., Shuster, M. J., and Levine, J. D. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1108-1112
38. Gold, M. S. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7645-7649
39. Baker, M. D., Chandra, S. Y., Ding, Y., Waxman, S. G., and Wood, J. N. (2003) J. Physiol. (Lond.) 548, 373-382