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Volumn 128, Issue 29, 2006, Pages 9352-9354

Total synthesis of ciguatoxin and 51-hydroxyCTX3C

Author keywords

[No Author keywords available]

Indexed keywords

51 HYDROXYCIGUATOXIN 3C; CIGUATOXIN; UNCLASSIFIED DRUG;

EID: 33746379107     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja063041p     Document Type: Article
Times cited : (94)

References (54)
  • 2
  • 18
    • 30744459350 scopus 로고    scopus 로고
    • For recent reviews on syntheses of polycyclic ethers, see: (a) Nakata, T. Chem. Rev. 2005, 105, 4314.
    • (2005) Chem. Rev. , vol.105 , pp. 4314
    • Nakata, T.1
  • 19
    • 30744476469 scopus 로고    scopus 로고
    • (b) Inoue, M. Chem. Rev. 2005, 105, 4379.
    • (2005) Chem. Rev. , vol.105 , pp. 4379
    • Inoue, M.1
  • 26
    • 33646441286 scopus 로고    scopus 로고
    • and references cited therein
    • (g) Hamajima, A.; Isobe, M. Org. Lett. 2006, 8, 1205 and references cited therein.
    • (2006) Org. Lett. , vol.8 , pp. 1205
    • Hamajima, A.1    Isobe, M.2
  • 41
    • 33746355717 scopus 로고    scopus 로고
    • note
    • 3] to the acrylate tailed to increase the yield of the 7-exo product due to the acid-sensitive nature of the O,S-acetal.
  • 45
    • 33746375466 scopus 로고    scopus 로고
    • note
    • Pentafluorophenyl esters 10d and 19d were more stable to hydrolysis than the 7-exo products presumably because of their vinylogous carbonate structures.
  • 51
    • 0001325114 scopus 로고    scopus 로고
    • NAP is known to be oxidatively removable similarly to p-methoxybenzyl. but is more acid-stable. For the development of our protective group strategy, see ref 8b. For NAP ether references, see: (a) Gaunt, M. J.; Yu. J.; Spencer, J. B. J. Org. Chem. 1998, 63, 4172.
    • (1998) J. Org. Chem. , vol.63 , pp. 4172
    • Gaunt, M.J.1    Yu, J.2    Spencer, J.B.3
  • 54
    • 33746382364 scopus 로고    scopus 로고
    • note
    • 50, intraperitoneal injection) of 1 and 2 was determined to be 1.64 and 0.31 μg/kg. respectively.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.