Glycerophospholipid synthesis as a novel drug target against cancer

Current Molecular Pharmacology

Volumn 4, Issue 3, 2011, Pages 167-175

  Dolce, Vincenza ^a   Cappello, Anna Rita ^a   Lappano, Rosamaria ^a   Maggiolini, Marcello ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Cancer; Glycerophospholipid synthesis; Lipogenesis; PI3K Akt pathway; Ras Raf ERK pathway

Indexed keywords

ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE CITRATE LYASE; ANTIPORTER; ARACHIDONIC ACID; CERULENIN; CT 32228; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTRADIOL; ESTROGEN RECEPTOR; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCEROPHOSPHOLIPID; LYSOPHOSPHATIDIC ACID; MEVALONIC ACID; MONOCLONAL ANTIBODY; MYCOTOXIN; PALMITIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PROTEIN KINASE; PROTEIN KINASE B; RITUXIMAB; SMALL INTERFERING RNA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; CANCER GROWTH; CELL STRAIN HCT116; CELL STRAIN MCF 7; CELL SURVIVAL; CELLULAR DISTRIBUTION; CHRONIC MYELOID LEUKEMIA; COLON CARCINOGENESIS; DISEASE ASSOCIATION; DRUG TARGETING; ENDOMETRIUM CANCER; FATTY ACID OXIDATION; GENE EXPRESSION; GLUCOSE METABOLISM; HEMATOLOGIC MALIGNANCY; HUMAN; LIPOGENESIS; MULTIPLE MYELOMA; MYELOID LEUKEMIA; NEOPLASM; NONHODGKIN LYMPHOMA; OVARY CANCER; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TUMOR CELL;

ANIMALS; ENZYME INHIBITORS; ENZYMES; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; GLYCEROPHOSPHOLIPIDS; HUMANS; LIPOGENESIS; NEOPLASMS; SIGNAL TRANSDUCTION;

EID: 80053527117     PISSN: 18744672     EISSN: 18744702     Source Type: Journal    
DOI: 10.2174/1874467211104030167     Document Type: Review

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