-
1
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
A. Grakoui, S. K. Bromley, C. Sumen, M. M. Davis, A. S. Shaw, P. M. Allen, M. L. Dustin, The immunological synapse: A molecular machine controlling T cell activation. Science 285, 221-227 (1999).
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
Davis, M.M.4
Shaw, A.S.5
Allen, P.M.6
Dustin, M.L.7
-
2
-
-
0031012266
-
Selective modulation of protein kinase C-θ during T-cell activation
-
C. R. Monks, H. Kupfer, I. Tamir, A. Barlow, A. Kupfer, Selective modulation of protein kinase C-θ during T-cell activation. Nature 385, 83-86 (1997).
-
(1997)
Nature
, vol.385
, pp. 83-86
-
-
Monks, C.R.1
Kupfer, H.2
Tamir, I.3
Barlow, A.4
Kupfer, A.5
-
3
-
-
66149112471
-
Spatiotemporal patterning during T cell activation is highly diverse
-
K. L. Singleton, K. T. Roybal, Y. Sun, G. Fu, N. R. Gascoigne, N. S. Van Oers, C. Wülfing, Spatiotemporal patterning during T cell activation is highly diverse. Sci. Signal. 2, ra15 (2009).
-
(2009)
Sci. Signal.
, vol.2
-
-
Singleton, K.L.1
Roybal, K.T.2
Sun, Y.3
Fu, G.4
Gascoigne, N.R.5
Van Oers, N.S.6
Wülfing, C.7
-
4
-
-
14544307446
-
T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells
-
B. Purtic, L. A. Pitcher, N. S. Van Oers, C. Wülfing, T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells. Proc. Natl. Acad. Sci. U.S.A. 102, 2904-2909 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2904-2909
-
-
Purtic, B.1
Pitcher, L.A.2
Van Oers, N.S.3
Wülfing, C.4
-
5
-
-
77951158406
-
Protein kinase C-θ mediates negative feedback on regulatory T cell function
-
A. Zanin-Zhorov, Y. Ding, S. Kumari, M. Attur, K. L. Hippen, M. Brown, B. R. Blazar, S. B. Abramson, J. J. Lafaille, M. L. Dustin, Protein kinase C-θ mediates negative feedback on regulatory T cell function. Science 328, 372-376 (2010).
-
(2010)
Science
, vol.328
, pp. 372-376
-
-
Zanin-Zhorov, A.1
Ding, Y.2
Kumari, S.3
Attur, M.4
Hippen, K.L.5
Brown, M.6
Blazar, B.R.7
Abramson, S.B.8
Lafaille, J.J.9
Dustin, M.L.10
-
6
-
-
69949185998
-
Coordination of Rho GTPase activities during cell protrusion
-
M. Machacek, L. Hodgson, C. Welch, H. Elliott, O. Pertz, P. Nalbant, A. Abell, G. L. Johnson, K. M. Hahn, G. Danuser, Coordination of Rho GTPase activities during cell protrusion. Nature 461, 99-103 (2009).
-
(2009)
Nature
, vol.461
, pp. 99-103
-
-
Machacek, M.1
Hodgson, L.2
Welch, C.3
Elliott, H.4
Pertz, O.5
Nalbant, P.6
Abell, A.7
Johnson, G.L.8
Hahn, K.M.9
Danuser, G.10
-
7
-
-
43049156015
-
Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks
-
S. R. Neves, P. Tsokas, A. Sarkar, E. A. Grace, P. Rangamani, S. M. Taubenfeld, C. M. Alberini, J. C. Schaff, R. D. Blitzer, I. I. Moraru, R. Iyengar, Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks. Cell 133, 666-680 (2008).
-
(2008)
Cell
, vol.133
, pp. 666-680
-
-
Neves, S.R.1
Tsokas, P.2
Sarkar, A.3
Grace, E.A.4
Rangamani, P.5
Taubenfeld, S.M.6
Alberini, C.M.7
Schaff, J.C.8
Blitzer, R.D.9
Moraru, I.I.10
Iyengar, R.11
-
8
-
-
0242497659
-
The immunological synapse balances T cell receptor signaling and degradation
-
K. H. Lee, A. R. Dinner, C. Tu, G. Campi, S. Raychaudhuri, R. Varma, T. N. Sims, W. R. Burack, H. Wu, J. Wang, O. Kanagawa, M. Markiewicz, P. M. Allen, M. L. Dustin, A. K. Chakraborty, A. S. Shaw, The immunological synapse balances T cell receptor signaling and degradation. Science 302, 1218-1222 (2003).
-
(2003)
Science
, vol.302
, pp. 1218-1222
-
-
Lee, K.H.1
Dinner, A.R.2
Tu, C.3
Campi, G.4
Raychaudhuri, S.5
Varma, R.6
Sims, T.N.7
Burack, W.R.8
Wu, H.9
Wang, J.10
Kanagawa, O.11
Markiewicz, M.12
Allen, P.M.13
Dustin, M.L.14
Chakraborty, A.K.15
Shaw, A.S.16
-
9
-
-
0037154747
-
T cell receptor signaling precedes immunological synapse formation
-
K. H. Lee, A. D. Holdorf, M. L. Dustin, A. C. Chan, P. M. Allen, A. S. Shaw, T cell receptor signaling precedes immunological synapse formation. Science 295, 1539-1542 (2002).
-
(2002)
Science
, vol.295
, pp. 1539-1542
-
-
Lee, K.H.1
Holdorf, A.D.2
Dustin, M.L.3
Chan, A.C.4
Allen, P.M.5
Shaw, A.S.6
-
10
-
-
0035655587
-
The immunological synapse of CTL contains a secretory domain and membrane bridges
-
J. C. Stinchcombe, G. Bossi, S. Booth, G. M. Griffiths, The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 15, 751-761 (2001).
-
(2001)
Immunity
, vol.15
, pp. 751-761
-
-
Stinchcombe, J.C.1
Bossi, G.2
Booth, S.3
Griffiths, G.M.4
-
11
-
-
17144384996
-
Tec family kinases in T lymphocyte development and function
-
L. J. Berg, L. D. Finkelstein, J. A. Lucas, P. L. Schwartzberg, Tec family kinases in T lymphocyte development and function. Annu. Rev. Immunol. 23, 549-600 (2005).
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 549-600
-
-
Berg, L.J.1
Finkelstein, L.D.2
Lucas, J.A.3
Schwartzberg, P.L.4
-
13
-
-
33745986018
-
+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk
-
+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. Immunity 25, 93-104 (2006).
-
(2006)
Immunity
, vol.25
, pp. 93-104
-
-
Broussard, C.1
Fleischacker, C.2
Horai, R.3
Chetana, M.4
Venegas, A.M.5
Sharp, L.L.6
Hedrick, S.M.7
Fowlkes, B.J.8
Schwartzberg, P.L.9
-
14
-
-
0033597440
-
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity
-
E. M. Schaeffer, J. Debnath, G. Yap, D. McVicar, X. C. Liao, D. R. Littman, A. Sher, H. E. Varmus, M. J. Lenardo, P. L. Schwartzberg, Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science 284, 638-641 (1999).
-
(1999)
Science
, vol.284
, pp. 638-641
-
-
Schaeffer, E.M.1
Debnath, J.2
Yap, G.3
McVicar, D.4
Liao, X.C.5
Littman, D.R.6
Sher, A.7
Varmus, H.E.8
Lenardo, M.J.9
Schwartzberg, P.L.10
-
15
-
-
0032543221
-
T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells
-
K. Q. Liu, S. C. Bunnell, C. B. Gurniak, L. J. Berg, T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. J. Exp. Med. 187, 1721-1727 (1998).
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1721-1727
-
-
Liu, K.Q.1
Bunnell, S.C.2
Gurniak, C.B.3
Berg, L.J.4
-
16
-
-
0033213484
-
+ T cells
-
+ T cells. Immunity 11, 399-409 (1999).
-
(1999)
Immunity
, vol.11
, pp. 399-409
-
-
Fowell, D.J.1
Shinkai, K.2
Liao, X.C.3
Beebe, A.M.4
Coffman, R.L.5
Littman, D.R.6
Locksley, R.M.7
-
17
-
-
34249854024
-
SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK
-
Y. Bogin, C. Ainey, D. Beach, D. Yablonski, SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK. Proc. Natl. Acad. Sci. U.S.A. 104, 6638-6643 (2007).
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 6638-6643
-
-
Bogin, Y.1
Ainey, C.2
Beach, D.3
Yablonski, D.4
-
18
-
-
19944431032
-
Kinaseindependent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton
-
D. Dombroski, R. A. Houghtling, C. M. Labno, P. Precht, A. Takesono, N. J. Caplen, D. D. Billadeau, R. L. Wange, J. K. Burkhardt, P. L. Schwartzberg, Kinaseindependent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. J. Immunol. 174, 1385-1392 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 1385-1392
-
-
Dombroski, D.1
Houghtling, R.A.2
Labno, C.M.3
Precht, P.4
Takesono, A.5
Caplen, N.J.6
Billadeau, D.D.7
Wange, R.L.8
Burkhardt, J.K.9
Schwartzberg, P.L.10
-
19
-
-
0037446773
-
Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor
-
J. A. Grasis, C. D. Browne, C. D. Tsoukas, Inducible T cell tyrosine kinase regulates actin-dependent cytoskeletal events induced by the T cell antigen receptor. J. Immunol. 170, 3971-3976 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 3971-3976
-
-
Grasis, J.A.1
Browne, C.D.2
Tsoukas, C.D.3
-
20
-
-
10744228513
-
Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP
-
C. M. Labno, C. M. Lewis, D. You, D. W. Leung, A. Takesono, N. Kamberos, A. Seth, L. D. Finkelstein, M. K. Rosen, P. L. Schwartzberg, J. K. Burkhardt, Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP. Curr. Biol. 13, 1619-1624 (2003).
-
(2003)
Curr. Biol.
, vol.13
, pp. 1619-1624
-
-
Labno, C.M.1
Lewis, C.M.2
You, D.3
Leung, D.W.4
Takesono, A.5
Kamberos, N.6
Seth, A.7
Finkelstein, L.D.8
Rosen, M.K.9
Schwartzberg, P.L.10
Burkhardt, J.K.11
-
21
-
-
73349137004
-
Hematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cγ1 Microcluster dynamics during T cell spreading
-
E. Carrizosa, T. S. Gomez, C. M. Labno, D. A. Klos Dehring, X. Liu, B. D. Freedman, D. D. Billadeau, J. K. Burkhardt, Hematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cγ1 Microcluster dynamics during T cell spreading. J. Immunol. 183, 7352-7361 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 7352-7361
-
-
Carrizosa, E.1
Gomez, T.S.2
Labno, C.M.3
Klos Dehring, D.A.4
Liu, X.5
Freedman, B.D.6
Billadeau, D.D.7
Burkhardt, J.K.8
-
22
-
-
33746215226
-
Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization
-
I. Tskvitaria-Fuller, A. Seth, N. Mistry, H. Gu, M. K. Rosen, C. Wülfing, Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization. J. Immunol. 177, 1708-1720 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 1708-1720
-
-
Tskvitaria-Fuller, I.1
Seth, A.2
Mistry, N.3
Gu, H.4
Rosen, M.K.5
Wülfing, C.6
-
23
-
-
33646053861
-
+ T cells to exert, but not gain, Th2 effector function
-
+ T cells to exert, but not gain, Th2 effector function. J. Immunol. 176, 3895-3899 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 3895-3899
-
-
Au-Yeung, B.B.1
Katzman, S.D.2
Fowell, D.J.3
-
24
-
-
8044250881
-
Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells
-
S. J. Szabo, A. S. Dighe, U. Gubler, K. M. Murphy, Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185, 817-824 (1997).
-
(1997)
J. Exp. Med.
, vol.185
, pp. 817-824
-
-
Szabo, S.J.1
Dighe, A.S.2
Gubler, U.3
Murphy, K.M.4
-
25
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
C. R. Monks, B. A. Freiberg, H. Kupfer, N. Sciaky, A. Kupfer, Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998).
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
26
-
-
0031759170
-
Kip1 induces cell migration
-
Kip1 induces cell migration. Nat. Med. 4, 1449-1452 (1998).
-
(1998)
Nat. Med.
, vol.4
, pp. 1449-1452
-
-
Nagahara, H.1
Vocero-Akbani, A.M.2
Snyder, E.L.3
Ho, A.4
Latham, D.G.5
Lissy, N.A.6
Becker-Hapak, M.7
Ezhevsky, S.A.8
Dowdy, S.F.9
-
27
-
-
33846200371
-
Protein transduction as a means of effective manipulation of Cdc42 activity in primary T cells
-
I. Tskvitaria-Fuller, N. Mistry, S. Sun, C. Wülfing, Protein transduction as a means of effective manipulation of Cdc42 activity in primary T cells. J. Immunol. Methods 319, 64-78 (2007).
-
(2007)
J. Immunol. Methods
, vol.319
, pp. 64-78
-
-
Tskvitaria-Fuller, I.1
Mistry, N.2
Sun, S.3
Wülfing, C.4
-
28
-
-
55349108147
-
Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation
-
S. Bécart, A. J. Balancio, C. Charvet, S. Feau, C. E. Sedwick, A. Altman, Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation. Immunity 29, 704-719 (2008).
-
(2008)
Immunity
, vol.29
, pp. 704-719
-
-
Bécart, S.1
Balancio, A.J.2
Charvet, C.3
Feau, S.4
Sedwick, C.E.5
Altman, A.6
-
29
-
-
0035905308
-
The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis
-
M. K. McGavin, K. Badour, L. A. Hardy, T. J. Kubiseski, J. Zhang, K. A. Siminovitch, The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis. J. Exp. Med. 194, 1777-1787 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1777-1787
-
-
McGavin, M.K.1
Badour, K.2
Hardy, L.A.3
Kubiseski, T.J.4
Zhang, J.5
Siminovitch, K.A.6
-
30
-
-
44349127316
-
αPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling
-
K. Missy, B. Hu, K. Schilling, A. Harenberg, V. Sakk, K. Kuchenbecker, K. Kutsche, K. D. Fischer, αPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling. Mol. Cell. Biol. 28, 3776-3789 (2008).
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3776-3789
-
-
Missy, K.1
Hu, B.2
Schilling, K.3
Harenberg, A.4
Sakk, V.5
Kuchenbecker, K.6
Kutsche, K.7
Fischer, K.D.8
-
31
-
-
18844449626
-
Vav-family proteins in T-cell signalling
-
V. L. Tybulewicz, Vav-family proteins in T-cell signalling. Curr. Opin. Immunol. 17, 267-274 (2005).
-
(2005)
Curr. Opin. Immunol.
, vol.17
, pp. 267-274
-
-
Tybulewicz, V.L.1
-
32
-
-
24944560377
-
A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
-
F. Stegmeier, G. Hu, R. J. Rickles, G. J. Hannon, S. J. Elledge, A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 102, 13212-13217 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 13212-13217
-
-
Stegmeier, F.1
Hu, G.2
Rickles, R.J.3
Hannon, G.J.4
Elledge, S.J.5
-
33
-
-
51349131307
-
The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality
-
S. Cemerski, J. Das, E. Giurisato, M. A. Markiewicz, P. M. Allen, A. K. Chakraborty, A. S. Shaw, The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality. Immunity 29, 414-422 (2008).
-
(2008)
Immunity
, vol.29
, pp. 414-422
-
-
Cemerski, S.1
Das, J.2
Giurisato, E.3
Markiewicz, M.A.4
Allen, P.M.5
Chakraborty, A.K.6
Shaw, A.S.7
-
34
-
-
77955382096
-
Transience in polarization of cytolytic effectors is required for efficient killing and controlled by Cdc42
-
P. Sinai, C. Nguyen, J. D. Schatzle, C. Wülfing, Transience in polarization of cytolytic effectors is required for efficient killing and controlled by Cdc42. Proc. Natl. Acad. Sci. U.S.A. 107, 11912-11917 (2010).
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 11912-11917
-
-
Sinai, P.1
Nguyen, C.2
Schatzle, J.D.3
Wülfing, C.4
-
35
-
-
0037144842
-
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
-
S. C. Bunnell, D. I. Hong, J. R. Kardon, T. Yamazaki, C. J.McGlade, V. A. Barr, L. E. Samelson, T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J. Cell Biol. 158, 1263-1275 (2002).
-
(2002)
J. Cell Biol.
, vol.158
, pp. 1263-1275
-
-
Bunnell, S.C.1
Hong, D.I.2
Kardon, J.R.3
Yamazaki, T.4
McGlade, C.J.5
Barr, V.A.6
Samelson, L.E.7
-
36
-
-
38049136514
-
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells
-
Y. Kaizuka, A. D. Douglass, R. Varma, M. L. Dustin, R. D. Vale, Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proc. Natl. Acad. Sci. U.S.A. 104, 20296-20301 (2007).
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 20296-20301
-
-
Kaizuka, Y.1
Douglass, A.D.2
Varma, R.3
Dustin, M.L.4
Vale, R.D.5
-
37
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
R. Varma, G. Campi, T. Yokosuka, T. Saito, M. L. Dustin, T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 25, 117-127 (2006).
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
38
-
-
30044441433
-
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
-
T. Yokosuka, K. Sakata-Sogawa, W. Kobayashi, M. Hiroshima, A. Hashimoto-Tane, M. Tokunaga, M. L. Dustin, T. Saito, Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat. Immunol. 6, 1253-1262 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1253-1262
-
-
Yokosuka, T.1
Sakata-Sogawa, K.2
Kobayashi, W.3
Hiroshima, M.4
Hashimoto-Tane, A.5
Tokunaga, M.6
Dustin, M.L.7
Saito, T.8
-
39
-
-
74049157769
-
TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation
-
B. F. Lillemeier, M. A. Mortelmaier, M. B. Forstner, J. B. Huppa, J. T. Groves, M. M. Davis, TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. Nat. Immunol. 11, 90-96 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 90-96
-
-
Lillemeier, B.F.1
Mortelmaier, M.A.2
Forstner, M.B.3
Huppa, J.B.4
Groves, J.T.5
Davis, M.M.6
-
40
-
-
0036856493
-
Optimizing anti-CD3 affinity for effective T cell targeting against tumor cells
-
N. Bortoletto, E. Scotet, Y. Myamoto, U. D'Oro, A. Lanzavecchia, Optimizing anti-CD3 affinity for effective T cell targeting against tumor cells. Eur. J. Immunol. 32, 3102-3107 (2002).
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 3102-3107
-
-
Bortoletto, N.1
Scotet, E.2
Myamoto, Y.3
D'Oro, U.4
Lanzavecchia, A.5
-
41
-
-
77949316162
-
Formation of a mast cell synapse: FcεRI membrane dynamics upon binding mobile or immobilized ligands on surfaces
-
A. Carroll-Portillo, K. Spendier, J. Pfeiffer, G. Griffiths, H. Li, K. A. Lidke, J. M. Oliver, D. S. Lidke, J. L. Thomas, B. S. Wilson, J. A. Timlin, Formation of a mast cell synapse: FcεRI membrane dynamics upon binding mobile or immobilized ligands on surfaces. J. Immunol. 184, 1328-1338 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 1328-1338
-
-
Carroll-Portillo, A.1
Spendier, K.2
Pfeiffer, J.3
Griffiths, G.4
Li, H.5
Lidke, K.A.6
Oliver, J.M.7
Lidke, D.S.8
Thomas, J.L.9
Wilson, B.S.10
Timlin, J.A.11
-
42
-
-
68849090313
-
Mechanisms and functions for the duration of intercellular contacts made by lymphocytes
-
D. M. Davis, Mechanisms and functions for the duration of intercellular contacts made by lymphocytes. Nat. Rev. Immunol. 9, 543-555 (2009).
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 543-555
-
-
Davis, D.M.1
-
44
-
-
0034176856
-
Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease
-
G. L. Costa, J. M. Benson, C. M. Seroogy, P. Achacoso, C. G. Fathman, G. P. Nolan, Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease. J. Immunol. 164, 3581-3590 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 3581-3590
-
-
Costa, G.L.1
Benson, J.M.2
Seroogy, C.M.3
Achacoso, P.4
Fathman, C.G.5
Nolan, G.P.6
-
45
-
-
0037341302
-
SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells
-
Y. Tanaka, K. Bi, R. Kitamura, S. Hong, Y. Altman, A. Matsumoto, H. Tabata, S. Lebedeva, P. J. Bushway, A. Altman, SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells. Immunity 18, 403-414 (2003).
-
(2003)
Immunity
, vol.18
, pp. 403-414
-
-
Tanaka, Y.1
Bi, K.2
Kitamura, R.3
Hong, S.4
Altman, Y.5
Matsumoto, A.6
Tabata, H.7
Lebedeva, S.8
Bushway, P.J.9
Altman, A.10
-
46
-
-
80053494855
-
-
note
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Acknowledgments: We thank L. Berg for Itk mutant constructs, J. Albanesi and G. Koretzky for the myosin 1C and SLP-76 GFP fusion proteins, and C. Happel and A. Hughson for technical help. Funding: The work was supported by grants from the NIH (to C.W., A.A., and D.J.F.) and the Medical Research Council (to V.L.J.T.). Author contributions: K.L.S. and C.W. designed the experiments; K.L.S., M.G., R.D.D., and C.W. executed the experiments and analyzed the data; B.B.A.-Y., O.K., V.L.J.T., A.A., and D.J.F. provided key reagents; V.L.J.T., A.A., and D.J.F. provided input in the preparation of the manuscript; and C.W. wrote the paper. Competing interests: The authors declare that they have no competing interests.
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