-
1
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
DOI 10.1016/S0092-8674(00)81333-1
-
KW Kinzler, B Vogelstein Lessons from hereditary colorectal cancer Cell 87 1996 159 170 (Pubitemid 26358996)
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
2
-
-
0031557898
-
The adenomatous polyposis coil (APC) tumor suppressor
-
DOI 10.1016/S0304-419X(97)00008-5, PII S0304419X97000085
-
P Polakis The adenomatous polyposis coli (APC) tumor suppressor Biochim Biophys Acta 1332 1997 F127 F147 (Pubitemid 27272621)
-
(1997)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1332
, Issue.3
-
-
Polakis, P.1
-
3
-
-
0031000489
-
Colon cancer. Molecular biology of the APC protein
-
RL White Colon cancer. Molecular biology of the APC protein Pathol Biol (Paris) 45 1997 240 244 (Pubitemid 27207337)
-
(1997)
Pathologie Biologie
, vol.45
, Issue.3
, pp. 240-244
-
-
White, R.L.1
-
5
-
-
0028957642
-
Mutations in the APC gene and their implications for protein structure and function
-
P Polakis Mutations in the APC gene and their implications for protein structure and function Curr Opin Genet Dev 5 1995 66 71
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 66-71
-
-
Polakis, P.1
-
6
-
-
33745276261
-
The Third 20 Amino Acid Repeat Is the Tightest Binding Site of APC for Beta-Catenin
-
DOI 10.1016/j.jmb.2006.04.064, PII S0022283606005572
-
J Liu, Y Xing, TR Hinds et al. The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin J Mol Biol 360 2006 133 144 (Pubitemid 43927813)
-
(2006)
Journal of Molecular Biology
, vol.360
, Issue.1
, pp. 133-144
-
-
Liu, J.1
Xing, Y.2
Hinds, T.R.3
Zheng, J.4
Xu, W.5
-
7
-
-
4344684495
-
Crystal structure of a Beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function
-
DOI 10.1016/j.molcel.2004.08.001, PII S1097276504004460
-
Y Xing, WK Clements, I Le Trong et al. Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function Mol Cell 15 2004 523 533 (Pubitemid 39141780)
-
(2004)
Molecular Cell
, vol.15
, Issue.4
, pp. 523-533
-
-
Xing, Y.1
Clements, W.K.2
Le Trong, I.3
Hinds, T.R.4
Stenkamp, R.5
Kimelman, D.6
Xu, W.7
-
8
-
-
0033895709
-
Wnt signaling and cancer
-
P Polakis Wnt signaling and cancer Genes Dev 14 2000 1837 1851 (Pubitemid 30639518)
-
(2000)
Genes and Development
, vol.14
, Issue.15
, pp. 1837-1851
-
-
Polakis, P.1
-
9
-
-
0031975738
-
The role of beta-catenin in cell adhesion, signal transduction, and cancer
-
LC Bullions, AJ Levine The role of beta-catenin in cell adhesion, signal transduction, and cancer Curr Opin Oncol 10 1998 81 87 (Pubitemid 28039246)
-
(1998)
Current Opinion in Oncology
, vol.10
, Issue.1
, pp. 81-87
-
-
Bullions, L.C.1
Levine, A.J.2
-
10
-
-
0032843036
-
Cadherins and catenins: Role in signal transduction and tumor progression
-
DOI 10.1023/A:1006200102166
-
J Behrens Cadherins and catenins: role in signal transduction and tumor progression Cancer Metastasis Rev 18 1999 15 30 (Pubitemid 29411089)
-
(1999)
Cancer and Metastasis Reviews
, vol.18
, Issue.1
, pp. 15-30
-
-
Behrens, J.1
-
11
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
LK Su, B Vogelstein, KW Kinzler Association of the APC tumor suppressor protein with catenins Science 262 1993 1734 1737 (Pubitemid 24030097)
-
(1993)
Science
, vol.262
, Issue.5140
, pp. 1734-1737
-
-
Su, L.-K.1
Vogelstein, B.2
Kinzler, K.W.3
-
12
-
-
0027738023
-
Association of the APC gene product with Beta-catenin
-
B Rubinfeld, B Souza, I Albert et al. Association of the APC gene product with beta-catenin Science 262 1993 1731 1734 (Pubitemid 24030096)
-
(1993)
Science
, vol.262
, Issue.5140
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
Munemitsu, S.7
Polakis, P.8
-
13
-
-
0028987249
-
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
-
S Munemitsu, I Albert, B Souza et al. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein Proc Natl Acad Sci USA 92 1995 3046 3050
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3046-3050
-
-
Munemitsu, S.1
Albert, I.2
Souza, B.3
-
14
-
-
0029664368
-
Binding of GSK3Beta to the APC-Beta-catenin complex and regulation of complex assembly
-
B Rubinfeld, I Albert, E Porfiri et al. Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly Science 272 1996 1023 1026 (Pubitemid 26259322)
-
(1996)
Science
, vol.272
, Issue.5264
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
15
-
-
0030978351
-
Beta-catenin is a target for the ubiquitin-proteasome pathway
-
H Aberle, A Bauer, J Stappert et al. beta-catenin is a target for the ubiquitin-proteasome pathway EMBO J 16 1997 3797 3804
-
(1997)
EMBO J
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
-
16
-
-
0030975671
-
Constitutive transcriptional activation by a Beta-catenin-Tcf complex in APC(-/-) colon carcinoma
-
DOI 10.1126/science.275.5307.1784
-
V Korinek, N Barker, PJ Morin et al. Constitutive transcriptional activation by a b-catenin-Tcf complex in APC-/- colon carcinoma Science 275 1997 1784 1787 (Pubitemid 27136714)
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
17
-
-
0030949463
-
Activation of Beta-catenin-Tcf signaling in colon cancer by mutations in Beta-catenin or APC
-
DOI 10.1126/science.275.5307.1787
-
PJ Morin, AB Sparks, V Korinek et al. Activation of b-catenin-Tcf signaling in colon cancer by mutations in b-catenin or APC Science 275 1997 1787 1790 (Pubitemid 27136715)
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
18
-
-
0030662273
-
Human cancer syndromes: Clues to the origin and nature of cancer
-
DOI 10.1126/science.278.5340.1043
-
ER Fearon Human cancer syndromes: clues to the origin and nature of cancer Science 278 1997 1043 1050 (Pubitemid 27517872)
-
(1997)
Science
, vol.278
, Issue.5340
, pp. 1043-1050
-
-
Fearon, E.R.1
-
19
-
-
0032483375
-
How a growth control path takes a wrong turn to cancer
-
1441.
-
E Pennisi How a growth control path takes a wrong turn to cancer Science 281 1998 1438 1439 1441.
-
(1998)
Science
, vol.281
, pp. 1438-1439
-
-
Pennisi, E.1
-
20
-
-
0032830931
-
TCF transcription factors: Molecular switches in carcinogenesis
-
DOI 10.1016/S0304-419X(99)00026-8, PII S0304419X99000268
-
J Roose, H Clevers TCF transcription factors: molecular switches in carcinogenesis Biochim Biophys Acta 1424 1999 M23 M37 (Pubitemid 29488713)
-
(1999)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1424
, Issue.2-3
-
-
Roose, J.1
Clevers, H.2
-
21
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
DOI 10.1126/science.281.5382.1509
-
TC He, AB Sparks, C Rago et al. Identification of c-MYC as a target of the APC pathway Science 281 1998 1509 1512 (Pubitemid 28425575)
-
(1998)
Science
, vol.281
, Issue.5382
, pp. 1509-1512
-
-
He, T.-C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
Da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
22
-
-
13044281685
-
Target genes of Beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas
-
DOI 10.1073/pnas.96.4.1603
-
B Mann, M Gelos, A Siedow et al. Target genes of β-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas Proc Natl Acad Sci USA 96 1999 1603 1608 (Pubitemid 29098498)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.4
, pp. 1603-1608
-
-
Mann, B.1
Gelos, M.2
Siedow, A.3
Hanski, M.L.4
Gratchev, A.5
Ilyas, M.6
Bodmer, W.F.7
Moyer, M.P.8
Riecken, E.O.9
Buhr, H.J.10
Hanski, C.11
-
23
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
DOI 10.1038/18884
-
O Tetsu, F McCormick β-catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 1999 422 426 (Pubitemid 29180374)
-
(1999)
Nature
, vol.398
, Issue.6726
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
24
-
-
0033545845
-
The cyclin D1 gene is a target of the Beta-catenin/LEF-1 pathway
-
DOI 10.1073/pnas.96.10.5522
-
M Shtutman, J Zhurinsky, I Simcha et al. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway Proc Natl Acad Sci USA 96 1999 5522 5527 (Pubitemid 29234650)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.10
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
Pestell, R.6
Ben-Ze'ev, A.7
-
25
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
SM Powell, N Zilz, Y Beazer-Barclay et al. APC mutations occur early during colorectal tumorigenesis Nature 359 1992 235 237
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
-
26
-
-
0032521433
-
Mutational analysis of the APC/Beta-catenin/Tcf pathway in colorectal cancer
-
AB Sparks, PJ Morin, B Vogelstein et al. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer Cancer Res 58 1998 1130 1134 (Pubitemid 28183198)
-
(1998)
Cancer Research
, vol.58
, Issue.6
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
27
-
-
0031984227
-
Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
-
M Takahashi, K Fukuda, T Sugimura et al. β-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors Cancer Res 58 1998 42 46 (Pubitemid 28027714)
-
(1998)
Cancer Research
, vol.58
, Issue.1
, pp. 42-46
-
-
Takahashi, M.1
Fukuda, K.2
Sugimura, T.3
Wakabayashi, K.4
-
28
-
-
0032521538
-
High frequency of Beta-catenin (CTNNB1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat
-
RH Dashwood, M Suzui, H Nakagama et al. High frequency of β-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat Cancer Res 58 1998 1127 1129 (Pubitemid 28183197)
-
(1998)
Cancer Research
, vol.58
, Issue.6
, pp. 1127-1129
-
-
Dashwood, R.H.1
Suzui, M.2
Nakagama, H.3
Sugimura, T.4
Nagao, M.5
-
29
-
-
0032958592
-
Frequent mutations of the rat Beta-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone
-
DOI 10.1002/(SICI)1098-2744(199903)24:3<232::AID-MC10>3.0.CO;2-M
-
M Suzui, T Ushijima, RH Dashwood et al. Frequent mutations of the rat beta-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone Mol Carcinog 24 1999 232 237 (Pubitemid 29169864)
-
(1999)
Molecular Carcinogenesis
, vol.24
, Issue.3
, pp. 232-237
-
-
Suzui, M.1
Ushijima, T.2
Dashwood, R.H.3
Yoshimi, N.4
Sugimura, T.5
Mori, H.6
Nagao, M.7
-
30
-
-
0033230616
-
Intestinal polyposis in mice with a dominant stable mutation of the Beta-catenin gene
-
DOI 10.1093/emboj/18.21.5931
-
N Harada, Y Tamai, T Ishikawa et al. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene EMBO J 18 1999 5931 5942 (Pubitemid 29515670)
-
(1999)
EMBO Journal
, vol.18
, Issue.21
, pp. 5931-5942
-
-
Harada, N.1
Tamai, Y.2
Ishikawa, T.-O.3
Sauer, B.4
Takaku, K.5
Oshima, M.6
Taketo, M.M.7
-
31
-
-
0033566821
-
Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated Beta-catenin
-
B Romagnolo, D Berrebi, S Saadi-Keddoucci et al. Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated beta-catenin Cancer Res 59 1999 3875 3879 (Pubitemid 29393543)
-
(1999)
Cancer Research
, vol.59
, Issue.16
, pp. 3875-3879
-
-
Romagnolo, B.1
Berrebi, D.2
Saadi-Keddoucci, S.3
Porteu, A.4
Pichard, A.-L.5
Peuchmaur, M.6
Vandewalle, A.7
Kahn, A.8
Perret, C.9
-
32
-
-
0033568145
-
Frequent mutation of Beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer
-
M Miyaki, T Iijima, J Kimura et al. Frequent mutation of beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer Cancer Res 59 1999 4506 4509 (Pubitemid 29428947)
-
(1999)
Cancer Research
, vol.59
, Issue.18
, pp. 4506-4509
-
-
Miyaki, M.1
Iijima, T.2
Kimura, J.3
Yasuno, M.4
Mori, T.5
Hayashi, Y.6
Koike, M.7
Shitara, N.8
Iwama, T.9
Kuroki, T.10
-
33
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
DOI 10.1242/jcs.00384
-
BW Doble, JR Woodgett GSK-3: tricks of the trade for a multi-tasking kinase J Cell Sci 116 2003 1175 1186 (Pubitemid 36410657)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.7
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
34
-
-
0034859101
-
The multifaceted roles of glycogen synthase kinase 3Beta in cellular signaling
-
DOI 10.1016/S0301-0082(01)00011-9, PII S0301008201000119
-
CA Grimes, RS Jope The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling Prog Neurobiol 65 2001 391 426 (Pubitemid 32781670)
-
(2001)
Progress in Neurobiology
, vol.65
, Issue.4
, pp. 391-426
-
-
Grimes, C.A.1
Jope, R.S.2
-
35
-
-
62849122466
-
Post-transcriptional regulation of cadherin-11 expression by GSK-3 and beta-catenin in prostate and breast cancer cells
-
AK Farina, YS Bong, CM Feltes et al. Post-transcriptional regulation of cadherin-11 expression by GSK-3 and beta-catenin in prostate and breast cancer cells PLoS ONE 4 2009 e4797
-
(2009)
PLoS ONE
, vol.4
, pp. 4797
-
-
Farina, A.K.1
Bong, Y.S.2
Feltes, C.M.3
-
36
-
-
0029683606
-
The axis-inducing activity, stability, and subcellular distribution of Beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
-
C Yost, M Torres, JR Miller et al. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3 Genes Dev 10 1996 1443 1454 (Pubitemid 26260702)
-
(1996)
Genes and Development
, vol.10
, Issue.12
, pp. 1443-1454
-
-
Yost, C.1
Torres, M.2
Miller, J.R.3
Huang, E.4
Kimelman, D.5
Moon, R.T.6
-
38
-
-
6844242339
-
Aberrant expression and phosphorylation of Beta-catenin in human colorectal cancer
-
T Takayama, H Shiozaki, Y Doki et al. Aberrant expression and phosphorylation of beta-catenin in human colorectal cancer Br J Cancer 77 1998 605 613 (Pubitemid 28059468)
-
(1998)
British Journal of Cancer
, vol.77
, Issue.4
, pp. 605-613
-
-
Takayama, T.1
Shiozaki, H.2
Doki, Y.3
Oka, H.4
Inoue, M.5
Yamamoto, M.6
Tamura, S.7
Shibamoto, S.8
Ito, F.9
Monden, M.10
-
39
-
-
0030805794
-
Patterns of - and Beta-catenin and E-cadherin expression in colorectal adenomas and carcinomas
-
DOI 10.1002/(SICI)1096-9896(199707)182:3<325::AID-PATH865>3.0.CO;2- Y
-
AA Van der Wurff, SJ Vermeulen, EP Van der Linden et al. Patterns of alpha- and beta-catenin and E-cadherin expression in colorectal adenomas and carcinomas J Pathol 182 1997 325 330 (Pubitemid 27285786)
-
(1997)
Journal of Pathology
, vol.182
, Issue.3
, pp. 325-330
-
-
Van Der Wurff, A.A.M.1
Vermeulen, S.J.T.2
Van Der Linden, E.P.M.3
Mareel, M.M.4
Bosman, F.T.5
Arends, J.-W.6
-
40
-
-
0030923587
-
Beta-Catenin mutations in cell lines established from human colorectal cancers
-
DOI 10.1073/pnas.94.19.10330
-
M Ilyas, IP Tomlinson, A Rowan et al. Beta-catenin mutations in cell lines established from human colorectal cancers Proc Natl Acad Sci USA 94 1997 10330 10334 (Pubitemid 27407041)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.19
, pp. 10330-10334
-
-
Ilyas, M.1
Tomlinson, I.P.M.2
Rowan, A.3
Pignatelli, M.4
Bodmer, W.F.5
-
41
-
-
0036783391
-
Elevated protein expression of cyclin D1 and Fra-1 but decreased expression of c-Myc in human colorectal adenocarcinomas overexpressing Beta-catenin
-
DOI 10.1002/ijc.10630
-
HL Wang, J Wang, SY Xiao et al. Elevated protein expression of cyclin D1 and Fra-1 but decreased expression of c-Myc in human colorectal adenocarcinomas overexpressing beta-catenin Int J Cancer 101 2002 301 310 (Pubitemid 34983184)
-
(2002)
International Journal of Cancer
, vol.101
, Issue.4
, pp. 301-310
-
-
Wang, H.L.1
Wang, J.2
Xiao, S.-Y.3
Haydon, R.4
Stoiber, D.5
He, T.-C.6
Bissonnette, M.7
Hart, J.8
-
42
-
-
0027930019
-
Use of a synthetic peptide as a selective substrate for glycogen synthase kinase 3
-
DOI 10.1006/abio.1994.1356
-
QM Wang, PJ Roach, CJ Fiol Use of a synthetic peptide as a selective substrate for glycogen synthase kinase 3 Anal Biochem 220 1994 397 402 (Pubitemid 24261187)
-
(1994)
Analytical Biochemistry
, vol.220
, Issue.2
, pp. 397-402
-
-
Wang, Q.M.1
Roach, P.J.2
Fiol, C.J.3
-
43
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
-
J Behrens, BA Jerchow, M Wurtele et al. Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β Science 280 1998 596 599
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
-
44
-
-
0032492954
-
Downregulation of Beta-catenin by human Axin and its association with the APC tumor suppressor, Beta-catenin and GSK3Beta
-
MJ Hart, R de los Santos, IN Albert et al. Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta Curr Biol 8 1998 573 581 (Pubitemid 28222891)
-
(1998)
Current Biology
, vol.8
, Issue.10
, pp. 573-581
-
-
Hart, M.J.1
De Los Santos, R.2
Albert, I.N.3
Rubinfeld, B.4
Polakis, P.5
-
45
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3Beta and Beta-catenin and promotes GSK-3Beta-dependent phosphorylation of Beta-catenin
-
DOI 10.1093/emboj/17.5.1371
-
S Ikeda, S Kishida, H Yamamoto et al. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin EMBO J 17 1998 1371 1384 (Pubitemid 28105516)
-
(1998)
EMBO Journal
, vol.17
, Issue.5
, pp. 1371-1384
-
-
Ikeda, S.1
Kishida, S.2
Yamamoto, H.3
Murai, H.4
Koyama, S.5
Kikuchi, A.6
-
46
-
-
0032079884
-
Axin, a negative regulator of the Wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of Beta-catenin
-
DOI 10.1074/jbc.273.18.10823
-
S Kishida, H Yamamoto, S Ikeda et al. Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin J Biol Chem 273 1998 10823 10826 (Pubitemid 28204914)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.18
, pp. 10823-10826
-
-
Kishida, S.1
Yamamoto, H.2
Ikeda, S.3
Kishida, M.4
Sakamoto, I.5
Koyama, S.6
Kikuchi, A.7
-
47
-
-
0031813650
-
Axin, an inhibitor of the Wnt signalling pathway, interacts with Beta- catenin, GSK-3Beta and APC and reduces the Beta-catenin level
-
T Nakamura, F Hamada, T Ishidate et al. Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level Genes Cells 3 1998 395 403 (Pubitemid 28387083)
-
(1998)
Genes to Cells
, vol.3
, Issue.6
, pp. 395-403
-
-
Nakamura, T.1
Hamada, F.2
Ishidate, T.3
Anai, K.-I.4
Kawahara, K.5
Toyoshima, K.6
Akiyama, T.7
-
49
-
-
0033574527
-
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
-
H Yamamoto, S Kishida, M Kishida et al. Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability J Biol Chem 274 1999 10681 10684
-
(1999)
J Biol Chem
, vol.274
, pp. 10681-10684
-
-
Yamamoto, H.1
Kishida, S.2
Kishida, M.3
-
50
-
-
23044444841
-
Deregulated GSK3Beta activity in colorectal cancer: Its association with tumor cell survival and proliferation
-
DOI 10.1016/j.bbrc.2005.07.041, PII S0006291X05014920
-
A Shakoori, A Ougolkov, ZW Yu et al. Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation Biochem Biophys Res Commun 334 2005 1365 1373 (Pubitemid 41074725)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.334
, Issue.4
, pp. 1365-1373
-
-
Shakoori, A.1
Ougolkov, A.2
Zhi, W.Y.3
Zhang, B.4
Modarressi, M.H.5
Billadeau, D.D.6
Mai, M.7
Takahashi, Y.8
Minamoto, T.9
-
51
-
-
84898700790
-
Mutations in the b-catenin gene (CTNNB1) are associated with increased protein expression of β-catenin, GSK-3β, and c-Myc in AOM-induced tumors
-
abstract
-
R Mustafi, Y Zhang, S Khare et al. Mutations in the b-catenin gene (CTNNB1) are associated with increased protein expression of β-catenin, GSK-3β, and c-Myc in AOM-induced tumors Gastroenterology 116 1999 A471 (abstract).
-
(1999)
Gastroenterology
, vol.116
, pp. 471
-
-
Mustafi, R.1
Zhang, Y.2
Khare, S.3
-
52
-
-
60549098654
-
Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity
-
S Song, N Mazurek, C Liu et al. Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity Cancer Res 69 2009 1343 1349
-
(2009)
Cancer Res
, vol.69
, pp. 1343-1349
-
-
Song, S.1
Mazurek, N.2
Liu, C.3
-
53
-
-
0033600239
-
The TAK1-NLK-MAPK-related pathway antagonizes signalling between Beta- catenin and transcription factor TCF
-
DOI 10.1038/21674
-
T Ishitani, J Ninomiya-Tsuji, S Nagai et al. The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF Nature 399 1999 798 802 (Pubitemid 29293177)
-
(1999)
Nature
, vol.399
, Issue.6738
, pp. 798-802
-
-
Ishitani, T.1
Ninomiya-Tsuji, J.2
Nagai, S.-I.3
Nishita, M.4
Meneghini, M.5
Barker, N.6
Waterman, M.7
Bowerman, B.8
Clevers, H.9
Shibuya, H.10
Matsumoto, K.11
-
54
-
-
0033486152
-
Beta-catenin signaling and cancer
-
PJ Morin beta-catenin signaling and cancer Bioessays 21 1999 1021 1030
-
(1999)
Bioessays
, vol.21
, pp. 1021-1030
-
-
Morin, P.J.1
-
55
-
-
42049098911
-
Human APC sequesters Beta-catenin even in the absence of GSK-3Beta in a Drosophila model
-
DOI 10.1038/sj.onc.1210890, PII 1210890
-
PR Rao, K Makhijani, LS Shashidhara Human APC sequesters beta-catenin even in the absence of GSK-3beta in a Drosophila model Oncogene 27 2008 2488 2493 (Pubitemid 351521097)
-
(2008)
Oncogene
, vol.27
, Issue.17
, pp. 2488-2493
-
-
Rao, P.R.1
Makhijani, K.2
Shashidhara, L.S.3
-
56
-
-
56649084987
-
Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample
-
K Nosho, N Irahara, K Shima et al. Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample PLoS ONE 3 2008 e3698
-
(2008)
PLoS ONE
, vol.3
, pp. 3698
-
-
Nosho, K.1
Irahara, N.2
Shima, K.3
-
57
-
-
33947259556
-
APC mutations and other genetic and epigenetic changes in colon cancer
-
DOI 10.1158/1541-7786.MCR-06-0398
-
WS Samowitz, ML Slattery, C Sweeney et al. APC mutations and other genetic and epigenetic changes in colon cancer Mol Cancer Res 5 2007 165 170 (Pubitemid 46423997)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.2
, pp. 165-170
-
-
Samowitz, W.S.1
Slattery, M.L.2
Sweeney, C.3
Herrick, J.4
Wolff, R.K.5
Albertsen, H.6
-
58
-
-
34547166662
-
Correlation of Beta-catenin localization with cyclooxygenase-2 expression and CpG Island Methylator Phenotype (CIMP) in colorectal cancer
-
DOI 10.1593/neo.07334
-
T Kawasaki, K Nosho, M Ohnishi et al. Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer Neoplasia 9 2007 569 577 (Pubitemid 47121831)
-
(2007)
Neoplasia
, vol.9
, Issue.7
, pp. 569-577
-
-
Kawasaki, T.1
Nosho, K.2
Ohnishi, M.3
Suemoto, Y.4
Kirkner, G.J.5
Dehari, R.6
Meyerhardt, J.A.7
Fuchs, C.S.8
Ogino, S.9
-
59
-
-
0034612636
-
Requirement for glycogen synthase kinase-3Beta in cell survival and NF-kappaB activation
-
DOI 10.1038/35017574
-
KP Hoeflich, J Luo, EA Rubie et al. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation Nature 406 2000 86 90 (Pubitemid 30460216)
-
(2000)
Nature
, vol.406
, Issue.6791
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.-S.4
Jin, O.5
Woodgett, J.R.6
-
60
-
-
0027478346
-
Negative regulation of Jun/AP-1: Conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy
-
RP de Groot, J Auwerx, M Bourouis et al. Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy Oncogene 8 1993 841 847 (Pubitemid 23087414)
-
(1993)
Oncogene
, vol.8
, Issue.4
, pp. 841-847
-
-
De Groot, R.P.1
Auwerx, J.2
Bourouis, M.3
Sassone-Corsi, P.4
-
61
-
-
0027512538
-
Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells
-
E Nikolakaki, PJ Coffer, R Hemelsoet et al. Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells Oncogene 8 1993 833 840 (Pubitemid 23087413)
-
(1993)
Oncogene
, vol.8
, Issue.4
, pp. 833-840
-
-
Nikolakaki, E.1
Coffer, P.J.2
Hemelsoet, R.3
Woodgett, J.R.4
Defize, L.H.K.5
-
62
-
-
0032533225
-
Glycogen synthase kinase-3Beta regulates cyclin D1 proteolysis and subcellular localization
-
JA Diehl, M Cheng, MF Roussel et al. Glycogen synthase kinase-3b regulates cyclin D1 proteolysis and subcellular localization Genes Dev 12 1998 3499 3511 (Pubitemid 28553242)
-
(1998)
Genes and Development
, vol.12
, Issue.22
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.J.4
-
63
-
-
4043088499
-
IKKBeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
-
FR Greten, L Eckmann, TF Greten et al. Ikkbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer Cell 118 2004 285 296 (Pubitemid 39061110)
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.-W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
64
-
-
62449130185
-
Knockin of mutant PIK3CA activates multiple oncogenic pathways
-
JP Gustin, B Karakas, MB Weiss et al. Knockin of mutant PIK3CA activates multiple oncogenic pathways Proc Natl Acad Sci USA 106 2009 2835 2840
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2835-2840
-
-
Gustin, J.P.1
Karakas, B.2
Weiss, M.B.3
-
65
-
-
55249120170
-
Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
-
Z Wang, KS Smith, M Murphy et al. Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy Nature 455 2008 1205 1209
-
(2008)
Nature
, vol.455
, pp. 1205-1209
-
-
Wang, Z.1
Smith, K.S.2
Murphy, M.3
-
66
-
-
33746239119
-
Glycogen synthase kinase-3Beta positively regulates the proliferation of human ovarian cancer cells
-
DOI 10.1038/sj.cr.7310078, PII 7310078
-
Q Cao, X Lu, YJ Feng Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells Cell Res 16 2006 671 677 (Pubitemid 44091443)
-
(2006)
Cell Research
, vol.16
, Issue.7
, pp. 671-677
-
-
Cao, Q.1
Lu, X.2
Feng, Y.-J.3
-
67
-
-
34147168760
-
Inactivation of glycogen synthase kinase-3Beta, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells
-
DOI 10.1158/1535-7163.MCT-06-0665
-
M Kunnimalaiyaan, AM Vaccaro, MA Ndiaye et al. Inactivation of glycogen synthase kinase-3beta, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells Mol Cancer Ther 6 2007 1151 1158 (Pubitemid 46554586)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.3
, pp. 1151-1158
-
-
Kunnimalaiyaan, M.1
Vaccaro, A.M.2
Ndiaye, M.A.3
Chen, H.4
-
68
-
-
0030458010
-
Increased apoptosis accompanies neoplastic development in the human colorectum
-
FA Sinicrope, G Roddey, TJ McDonnell et al. Increased apoptosis accompanies neoplastic development in the human colorectum Clin Cancer Res 2 1996 1999 2006 (Pubitemid 27006632)
-
(1996)
Clinical Cancer Research
, vol.2
, Issue.12
, pp. 1999-2006
-
-
Sinicrope, F.A.1
Roddey, G.2
McDonnell, T.J.3
Shen, Y.4
Cleary, K.R.5
Stephens, L.C.6
-
69
-
-
25444519182
-
Pharmacologic modulation of glycogen synthase kinase-3Beta promotes p53-dependent apoptosis through a direct bax-mediated mitochondrial pathway in colorectal cancer cells
-
DOI 10.1158/0008-5472.CAN-05-1226
-
J Tan, L Zhuang, HS Leong et al. Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells Cancer Res 65 2005 9012 9020 (Pubitemid 41377393)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 9012-9020
-
-
Tan, J.1
Zhuang, L.2
Leong, H.-S.3
Iyer, N.G.4
Liu, E.T.5
Yu, Q.6
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