Patterns of α- and β-catenin and E-cadherin expression in colorectal adenomas and carcinomas

Journal of Pathology

Volumn 182, Issue 3, 1997, Pages 325-330

  Van Der Wurff, Anna A M ^a   Vermeulen, Stefan J T ^b   Van Der Linden, Edith P M ^c   Mareel, Marc M ^b   Bosman, Fred T ^d   Arends, Jan Willem ^c  

^a CPRLab   (Netherlands)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

catenin; catenin; Colorectal carcinoma; E cadherin; Liver metastases; Lymph node metastasis

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CATENIN; CELL ADHESION MOLECULE; UVOMORULIN;

ADENOMA; ARTICLE; CANCER INVASION; CLINICAL ARTICLE; COLORECTAL CARCINOMA; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; LYMPH NODE METASTASIS; PRIORITY JOURNAL; PROGNOSIS;

ADENOCARCINOMA; ADENOMA; ALPHA CATENIN; BETA CATENIN; CADHERINS; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CYTOSKELETAL PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; TRANS-ACTIVATORS;

EID: 0030805794     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199707)182:3<325::AID-PATH865>3.0.CO;2-Y     Document Type: Article

References (24)

1. Edelman GM, Crossin KL. Cell adhesion molecules: implications for a molecular histology. Annu Rev Biochem 1991; 60: 155-190.
2. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 1991; 251: 1451-1455.
3. Takeichi M. Cadherins: a molecular family important in selective cell-cell adhesion. Annu Rev Biochem 1990; 59: 237-252.
4. Ozawa M, Ringwald M, Kemler R. Uvomoruilin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc Natl Acad Sci USA 1990; 87: 4246-4250.
5. Vleminckx K, Vakaet L Jr, Marcel M, Fiers W, van-Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991; 66: 107-119.
6. Dorudi S, Sheffield JP, Poulsom R, Northover JM, Hart IR. E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am J Pathol 1993; 142: 981-986.
7. Schipper JH, Frixen UH, Behrens J, Unger A, Jahnke K, Birchmeier W. E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res 1991; 51: 6328-6337.
8. Mareel M, Bracke M, Van-Roy F. Invasion promoter versus invasion suppressor molecules: the paradigm of E-cadherin. Mol Biol Rep 1994; 19: 45-67.
9. van-der-Wurff AA, ten-Kate J, van-der-Linden EP, Dinjens WN, Arends JW, Bosman FT. L-CAM expression in normal, premalignant, and malignant colon mucosa. J Pathol 1992; 168: 287-291.
10. Shimoyama Y, Nagafuchi A, Fujita S, et al. Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesiveness. Cancer Res 1992; 52: 5770-5774.
11. Morton RA, Ewing CM, Nagafuchi A, Tsukita S, Isaacs WB. Reduction of E-cadherin levels and deletion of the alpha-catenin gene in human prostate cancer cells. Cancer Res 1993; 53: 3585-3590.
12. Breen E, Clarke A, Steele G Jr, Mercurio AM. Poorly differentiated colon carcinoma cell lines deficient in alpha-catenin expression express high levels of surface E-cadherin but lack Ca(2+)-dependent cell-cell adhesion. Cell Adhes Commun 1993; 1: 239-250.
13. Vermeulen SJ, Bruyneel EA, Bracke ME, et al. Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells. Cancer Res 1995; 55: 4722-4728.
14. Shiozaki H, Iihara K, Oka H, et al. Immunohistochemical detection of alpha-catenin expression in human cancers. Am J Pathol 1994; 144: 667-674.
15. Kadowaki T, Shiozaki H, Inoue M, et al. E-cadherin and alpha-catenin expression in human esophageal cancer. Cancer Res 1994; 54: 291-296.
16. Matsui S, Shiozaki H, Inoue M, et al. Immunohistochemical evaluation of alpha-catenin expression in human gastric cancer. Virchows Arch 1994; 424: 375-381.
17. van-der-Wurff AA, Arends JW, van-der-Linden EP, ten-Kate J, Bosman FT. L-CAM expression in lymph node and liver metastases of colorectal carcinomas. J Pathol 1994; 172: 177-181.
18. Vermeulen SJ, Bruyneel EA, Roy FM van, Mareel MM, Bracke ME. Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid. Br J Cancer 1995; 72: 1447-1453.
19. Frixen UH, Behrens J, Sachs M, et at. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 1991; 113: 173-185.
20. Takayama T, Shiozaki H, Shibamoto S, et al. β-catenin expression in human cancers. Am J Pathol 1996; 148: 39-46.
21. Behrens J, Vakaet L, Friis R, et al. Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/ beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol 1993; 120: 757-766.
22. Shiozaki H, Kadowaki T, Doki Y, et al. Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line. Br J Cancer 1995; 71: 250-258.
23. Su LK, Vogelstein B, Kinzler KW. Association of the APC tumor suppressor protein with catenins. Science 1993; 262: 1734-1737.
24. Rubinfeld B, Souza B, Albert I, et al. Association of the APC gene product with beta-catenin. Science 1993; 262: 1731-1734.