Post-transcriptional regulation of cadherin-11 expression by GSK-3 and β-catenin in prostate and breast cancer cells

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Farina, Anne K ^a   Bong, Yong Sik ^a   Feltes, Carolyn M ^a   Byers, Stephen W ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CADHERIN; CADHERIN 11; CELL PROTEIN; DICER; LITHIUM CHLORIDE; MESSENGER RNA; MICRORNA; OXIME; PROTEIN GSK3; RNA POLYMERASE II; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE KINASE 3; OSTEOBLAST CADHERIN;

3' UNTRANSLATED REGION; ARTICLE; BREAST CANCER; CELL DENSITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOSTASIS; HUMAN; HUMAN CELL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN STABILITY; TRANSCRIPTION REGULATION; BREAST TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; PHYSIOLOGY; PROSTATE TUMOR; PROTEIN SYNTHESIS; RNA STABILITY;

3' UNTRANSLATED REGIONS; BETA CATENIN; BREAST NEOPLASMS; CADHERINS; FEMALE; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MALE; PROSTATIC NEOPLASMS; PROTEIN BIOSYNTHESIS; RNA STABILITY; RNA, MESSENGER;

EID: 62849122466     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004797     Document Type: Article

References (43)

1. Simonneau L, Kitagawa M, Suzuki S, Thiery JP (1995) Cadherin 11 expression marks the mesenchymal phenotype: towards new functions for cadherins? Cell Adhes Commun 3: 115-130.
2. Kiener HP, Lee DM, Agarwal SK, Brenner MB (2006) Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro. Am J Pathol 168: 1486-1499.
3. Lee DM, Kiener HP, Agarwal SK, Noss EH, Watts GF, et al. (2007) Cadherin-11 in synovial lining formation and pathology in arthritis. Science 315: 1006-1010.
4. Bussemakers MJ, Van Bokhoven A, Tomita K, Jansen CF, Schalken JA (2000) Complex cadherin expression in human prostate cancer cells. Int J Cancer 85: 446-450.
5. Guise TA (2000) Molecular mechanisms of osteolytic bone metastases. Cancer 88: 2892-2898.
6. Guise TA, Chirgwin JM (2003) Transforming growth factor-beta in osteolytic breast cancer bone metastases. Clin Orthop. pp S32-38.
7. Pishvaian MJ, Feltes CM, Thompson P, Bussemakers MJ, Schalken JA, et al. (1999) Cadherin-11 is expressed in invasive breast cancer cell lines. Cancer Res 59: 947-952.
8. Tomita K, van Bokhoven A, van Leenders GJ, Ruijter ET, Jansen CF, et al. (2000) Cadherin switching in human prostate cancer progression. Cancer Res 60: 3650-3654.
9. Chen GT, Getsios S, MacCalman CD (1999) Cadherin-11 is a hormonally regulated cellular marker of decidualization in human endometrial stromal cells. Mol Reprod Dev 52: 158-165.
10. Getsios S, Chen GT, Huang DT, MacCalman CD (1998) Regulated expression of cadherin-11 in human extravillous cytotrophoblasts undergoing aggregation and fusion in response to transforming growth factor beta 1. J Reprod Fertil 114: 357-363.
11. Hadeball B, Borchers A, Wedlich D (1998) Xenopus cadherin-11 (Xcadherin-11) expression requires the Wg/Wnt signal. Mech Dev 72: 101-113.
12. Vallin J, Girault JM, Thiery JP, Broders F (1998) Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells. Mech Dev 75: 171-174.
13. Laney JD, Hochstrasser M (1999) Substrate targeting in the ubiquitin system. Cell 97: 427-430.
14. Maniatis T (1999) A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev 13: 505-510.
15. Orford K, Crockett C, Jensen JP, Weissman AM, Byers SW (1997) Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin. J Biol Chem 272: 24735-24738.
16. Yook JI, Li XY, Ota I, Hu C, Kim HS, et al. (2006) A Wnt-Axin2-GSK3-beta cascade regulates Snail1 activity in breast cancer cells. Nat Cell Biol 8: 1398-1406.
17. Polakis P (2000) Wnt signaling and cancer. Genes Dev 14: 1837-1851.
18. Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789.
19. Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH (2004) Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 10: 55-63.
20. Stambolic V, Ruel L, Woodgett JR (1996) Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr Biol 6: 1664-1668.
21. McMenamin ME, Soung P, Perera S, Kaplan I, Loda M, et al. (1999) Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res 59: 4291-4296.
22. Zhou BP, Deng J, Xia W, Xu J, Li YM, et al. (2004) Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 6: 931-940.
23. Doench JG, Petersen CP, Sharp PA (2003) siRNAs can function as miRNAs. Genes Dev 17: 438-442.
24. Doench JG, Sharp PA (2004) Specificity of microRNA target selection in translational repression. Genes Dev 18: 504-511.
25. Petersen CP, Bordeleau ME, Pelletier J, Sharp PA (2006) Short RNAs repress translation after initiation in mammalian cells. Mol Cell 21: 533-542.
26. Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, et al. (1996) Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 272: 1023-1026.
27. Chirgwin JM, Guise TA (2000) Molecular mechanisms of tumor-bone interactions in osteolytic metastases. Crit Rev Eukaryot Gene Expr 10: 159-178.
28. Ohigashi T, Mizuno R, Nakashima J, Marumo K, Murai M (2005) Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells. Prostate 62: 61-68.
29. Hu X, Paik PK, Chen J, Yarilina A, Kockeritz L, et al. (2006) IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity 24: 563-574.
30. Whittle BJ, Varga C, Posa A, Molnar A, Collin M, et al. (2006) Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta. Br J Pharmacol 147: 575-582.
31. Barker N, Morin PJ, Clevers H (2000) The Yin-Yang of TCF/beta-catenin signaling. Adv Cancer Res 77: 1-24.
32. Easwaran V, Pishvaian M, Salimuddin, Byers S (1999) Cross-regulation of betacatenin-LEF/TCF and retinoid signaling pathways. Curr Biol 9: 1415-1418.
33. Shah S, Islam MN, Dakshanamurthy S, Rizvi I, Rao M, et al. (2006) The molecular basis of vitamin D receptor and beta-catenin crossregulation. Mol Cell 21: 799-809.
34. Edwards TA, Pyle SE, Wharton RP, Aggarwal AK (2001) Structure of Pumilio reveals similarity between RNA and peptide binding motifs. Cell 105: 281-289.
35. Lee HK, Choi YS, Park YA, Jeong S (2006) Modulation of oncogenic transcription and alternative splicing by beta-catenin and an RNA aptamer in colon cancer cells. Cancer Res 66: 10560-10566.
36. Lee HK, Jeong S (2006) Beta-Catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3′-UTR. Nucleic Acids Res 34: 5705-5714.
37. Lee HK, Kwak HY, Hur J, Kim IA, Yang JS, et al. (2007) beta-catenin regulates multiple steps of RNA metabolism as revealed by the RNA aptamer in colon cancer cells. Cancer Res 67: 9315-9321.
38. Orlandini M, Semboloni S, Oliviero S (2003) Beta-catenin inversely regulates vascular endothelial growth factor-D mRNA stability. J Biol Chem 278: 44650-44656.
39. Chendrimada TP, Finn KJ, Ji X, Baillat D, Gregory RI, et al. (2007) MicroRNA silencing through RISC recruitment of eIF6. Nature 447: 823-828.
40. Ji Y, Shah S, Soanes K, Islam MN, Hoxter B, et al. (2008) Eukaryotic initiation factor 6 selectively regulates Wnt signaling and beta-catenin protein synthesis. Oncogene 27: 755-762.
41. Biffo S, Sanvito F, Costa S, Preve L, Pignatelli R, et al. (1997) Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells. J Biol Chem 272: 30314-30321.
42. Yamasaki H, Sekimoto T, Ohkubo T, Douchi T, Nagata Y, et al. (2005) Zinc finger domain of Snail functions as a nuclear localization signal for importin beta-mediated nuclear import pathway. Genes Cells 10: 455-464.
43. Dussault AA, Pouliot M (2006) Rapid and simple comparison of messenger RNA levels using real-time PCR. Biol Proced Online 8: 1-10.