Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by polyic in vivo

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Fuertes Marraco, Silvia A ^a   Scott, Clare L ^b,c   Bouillet, Philippe ^b,c   Ives, Annette ^a   Masina, Slavica ^a   Vremec, David ^b   Jansen, Elisa S ^b   O'Reilly, Lorraine A ^b,c   Schneider, Pascal ^a   Fasel, Nicolas ^a   Shortman, Ken ^b,c   Strasser, Andreas ^b,c   Acha Orbea, Hans ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BH3 PROTEIN; BIM PROTEIN; CD11B ANTIGEN; INTERFERON; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN BCL 2; PROTEIN BID; PROTEIN MAVS; PROTEIN NOXA; PUMA PROTEIN; SIGNAL PEPTIDE; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CROSS PRESENTATION; CYTOTOXIC LYMPHOCYTE; DENDRITIC CELL; DRUG EFFECT; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; IMMUNE DEFICIENCY; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INTERFERON INDUCTION; INTERFERON PRODUCTION; LEISHMANIASIS; LYMPHOCYTE COUNT; MALE; MOUSE; NONHUMAN; PROTEIN FUNCTION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

MUS;

EID: 80053354500     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020189     Document Type: Article

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